FI960364A0 - Uusia 1,4-(difenyylialkyyli)piperatsiinijohdoksia - Google Patents

Uusia 1,4-(difenyylialkyyli)piperatsiinijohdoksia

Info

Publication number
FI960364A0
FI960364A0 FI960364A FI960364A FI960364A0 FI 960364 A0 FI960364 A0 FI 960364A0 FI 960364 A FI960364 A FI 960364A FI 960364 A FI960364 A FI 960364A FI 960364 A0 FI960364 A0 FI 960364A0
Authority
FI
Finland
Prior art keywords
diphenylalkyl
new
different
same
piperazine derivatives
Prior art date
Application number
FI960364A
Other languages
English (en)
Swedish (sv)
Other versions
FI960364A (fi
Inventor
Yoichi Kawashima
Junzo Matsumoto
Kiyoshi Matsuno
Toshihiko Senda
Keiko Hirano
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Publication of FI960364A publication Critical patent/FI960364A/fi
Publication of FI960364A0 publication Critical patent/FI960364A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI960364A 1993-07-28 1996-01-26 Uusia 1,4-(difenyylialkyyli)piperatsiinijohdoksia FI960364A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP18583993 1993-07-28
PCT/JP1994/001220 WO1995004050A1 (fr) 1993-07-28 1994-07-25 Nouveau derive de 1,4-di(phenylalkyl)piperazine

Publications (2)

Publication Number Publication Date
FI960364A FI960364A (fi) 1996-01-26
FI960364A0 true FI960364A0 (fi) 1996-01-26

Family

ID=16177784

Family Applications (1)

Application Number Title Priority Date Filing Date
FI960364A FI960364A0 (fi) 1993-07-28 1996-01-26 Uusia 1,4-(difenyylialkyyli)piperatsiinijohdoksia

Country Status (11)

Country Link
US (1) US5736546A (fi)
EP (1) EP0711763B1 (fi)
KR (1) KR100299734B1 (fi)
CN (1) CN1042029C (fi)
AT (1) ATE197047T1 (fi)
CA (1) CA2168264A1 (fi)
DE (1) DE69426157T2 (fi)
ES (1) ES2151930T3 (fi)
FI (1) FI960364A0 (fi)
NO (1) NO960270D0 (fi)
WO (1) WO1995004050A1 (fi)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5859295A (en) * 1994-12-05 1999-01-12 University Of Kentucky Research Foundation Canavanine analogs and their use as chemotherapeutic agents
US5889006A (en) * 1995-02-23 1999-03-30 Schering Corporation Muscarinic antagonists
IL117149A0 (en) * 1995-02-23 1996-06-18 Schering Corp Muscarinic antagonists
HUP9601331A3 (en) * 1996-05-17 2000-06-28 Egyt Gyogyszervegyeszeti Gyar Piperazine- and homopiperazine-derivatives, process for producing them and pharmaceutical compositions containing them
WO1998001425A1 (en) * 1996-07-10 1998-01-15 Schering Corporation 1,4-di-sustituted piperidines as muscarinic antagonists
US5952349A (en) * 1996-07-10 1999-09-14 Schering Corporation Muscarinic antagonists for treating memory loss
US5860391A (en) * 1996-08-06 1999-01-19 First Brands Corporation Absorbents containing activated carbons
US6713651B1 (en) * 1999-06-07 2004-03-30 Theravance, Inc. β2-adrenergic receptor agonists
CA2349452C (en) 1998-11-09 2009-02-10 Santen Pharmaceutical Co., Ltd. Therapeutic agents for drug dependence
AU5569800A (en) * 1999-06-30 2001-01-31 Santen Pharmaceutical Co. Ltd. Brain sigma-1 receptor-binding ligand
DE10050236A1 (de) * 2000-10-11 2002-04-25 Merck Patent Gmbh Verwendung bestimmter Substanzen, die an den Sigma-Rezeptor binden, zur Behandlung von Sarkomen und Karzinomen
CN1181065C (zh) * 2002-05-08 2004-12-22 上海医药工业研究院 芳烷甲酰烷基哌嗪衍生物及其作为脑神经保护剂的应用
CN1172919C (zh) 2002-06-03 2004-10-27 上海医药工业研究院 芳烷醇哌嗪衍生物及其在制备抗抑郁症药物中的应用
US20050032827A1 (en) * 2003-06-12 2005-02-10 Donna Oksenberg Sigma ligands for neuronal regeneration and functional recovery
WO2005028457A1 (en) * 2003-09-23 2005-03-31 Fermion Oy Preparation of quetiapine
DE102004061593A1 (de) * 2004-12-21 2006-06-22 Abbott Gmbh & Co. Kg Substituierte N-heterocyclische Verbindungen und ihre therapeutische Verwendung
JP2009504648A (ja) * 2005-08-09 2009-02-05 株式会社エムズサイエンス ピペラジン誘導体
WO2008096189A2 (en) * 2005-09-23 2008-08-14 M's Science Corporation Piperidine and piperazine derivatives
EP2377530A3 (en) 2005-10-21 2012-06-20 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
US20070112017A1 (en) 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
AU2007210251A1 (en) 2006-01-27 2007-08-09 M's Science Corporation Piperidine and piperazine derivatives
CN101384260A (zh) * 2006-02-15 2009-03-11 株式会社爱慕知科学 哌嗪衍生物
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7678808B2 (en) 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
EP2377531A2 (en) 2006-05-09 2011-10-19 Braincells, Inc. Neurogenesis by modulating angiotensin
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2008060271A1 (en) * 2006-11-13 2008-05-22 M's Science Corporation Sigma ligands for neuronal regeneration and functional recovery
WO2009128057A2 (en) * 2008-04-18 2009-10-22 UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN et al Psycho-pharmaceuticals
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
US8673920B2 (en) 2009-05-06 2014-03-18 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9073882B2 (en) 2010-10-27 2015-07-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2012058134A1 (en) 2010-10-29 2012-05-03 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
BR112014003801A2 (pt) 2011-08-19 2017-03-07 Merck Sharp & Dohme composto, composição farmacêutica, e, métodos para a inibição de romk, para a provocação de diurese, natriurese ou ambas, e para o tratamento ou a profilaxia de um ou mais distúrbios
WO2013039802A1 (en) 2011-09-16 2013-03-21 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US8999991B2 (en) 2011-10-25 2015-04-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US8999990B2 (en) 2011-10-25 2015-04-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2013066717A1 (en) 2011-10-31 2013-05-10 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9139585B2 (en) 2011-10-31 2015-09-22 Merck Sharp & Dohme Corp. Inhibitors of the Renal Outer Medullary Potassium channel
EP2773351B1 (en) 2011-10-31 2017-08-23 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9206199B2 (en) 2011-12-16 2015-12-08 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
AR092031A1 (es) 2012-07-26 2015-03-18 Merck Sharp & Dohme Inhibidores del canal de potasio medular externo renal
WO2014085210A1 (en) 2012-11-29 2014-06-05 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
EP2934533B1 (en) 2012-12-19 2017-11-15 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9604998B2 (en) 2013-02-18 2017-03-28 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
EP2968288B1 (en) 2013-03-15 2018-07-04 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
EP3027625B1 (en) 2013-07-31 2018-05-30 Merck Sharp & Dohme Corp. Spiro-fused derivatives of piperidine useful for the treatment of inter alia hypertension and acute or chronic heart failure
US9951052B2 (en) 2013-10-31 2018-04-24 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2016127358A1 (en) 2015-02-12 2016-08-18 Merck Sharp & Dohme Corp. Inhibitors of renal outer medullary potassium channel

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5583771A (en) * 1978-12-20 1980-06-24 Kanebo Ltd N-substituted trimethoxybenzylpiperazine derivative and its acid addition salt
JPS60155171A (ja) * 1983-12-10 1985-08-15 Wako Pure Chem Ind Ltd ポリメトキシベンジルピペラジン誘導体
JPS6133827A (ja) * 1984-07-27 1986-02-17 Mitsubishi Electric Corp 放電加工装置
JP2722250B2 (ja) * 1989-05-30 1998-03-04 興和株式会社 新規なジアミン化合物及びこれを含有する脳機能障害改善剤
EP0507863A4 (en) * 1989-12-28 1993-07-07 Virginia Commonwealth University Sigma receptor ligands and the use thereof
EP0566189A1 (en) * 1992-04-13 1993-10-20 Akzo N.V. Psychotropic piperazine derivative
US5428037A (en) * 1993-04-09 1995-06-27 Syntex Pharmaceuticals, Ltd. Heterocyclic derivatives in the treatment of Ischaemia and related diseases

Also Published As

Publication number Publication date
EP0711763B1 (en) 2000-10-18
FI960364A (fi) 1996-01-26
DE69426157D1 (de) 2000-11-23
US5736546A (en) 1998-04-07
NO960270L (no) 1996-01-23
ATE197047T1 (de) 2000-11-15
ES2151930T3 (es) 2001-01-16
DE69426157T2 (de) 2001-05-17
EP0711763A4 (fi) 1996-06-12
CN1128026A (zh) 1996-07-31
KR100299734B1 (ko) 2002-01-09
WO1995004050A1 (fr) 1995-02-09
NO960270D0 (no) 1996-01-23
EP0711763A1 (en) 1996-05-15
CN1042029C (zh) 1999-02-10
CA2168264A1 (en) 1995-02-09

Similar Documents

Publication Publication Date Title
FI960364A0 (fi) Uusia 1,4-(difenyylialkyyli)piperatsiinijohdoksia
PT778277E (pt) Derivados heterociclicos substituidos como antagonistas do crf
ATE264856T1 (de) Heterocyclisch substituierte benzolderivate und herbizide
FI903331A0 (fi) Substituerade kinazolinoner, vilka aer anvaendbara som angiotensin-ii-antagonister.
ATE91684T1 (de) 1,2-cyclohexylaminoarylamide zu verwendung als analgetika.
DE69028136D1 (de) Alkoxyiminoacetamid-Derivate und ihre Verwendung als pilztötendes Mittel
ATE71373T1 (de) 1,4-disubstituierte piperazin-verbindungen, ihre herstellung und ihre verwendung.
ATE119774T1 (de) Imidazopyridinderivate und ihre verwendung.
DE69021639D1 (de) Disäuren von Diarylstyrylchinolin.
AU9281198A (en) Benzofuran derivatives
DK240084D0 (da) New beta-carboline-3-oxadiazolyl derivatives
TR199500954A1 (tr) Yeni pirokarbazoller.
ES2061794T3 (es) Nuevos derivados de benzazepina.
DE69906243D1 (de) 2-Indanmethanolderivate und ihre Verwendung als Riechstoffe
DE69624459D1 (de) Kondensierte indan-derivate und ihre salze
ATE396187T1 (de) Indolmethyl-n,n'-bisacylpiperazine als neurokininrezeptorantagonisten
ATE61580T1 (de) 3-propenylpyridine und ihre verwendung als fungizide.
ATE148449T1 (de) Neue verwendung von (s) amino-2-dichloro-3,4- benzyl)-2-propanol-1 enantiomere derivate

Legal Events

Date Code Title Description
FD Application lapsed