ATE113282T1 - Heteroaryl piperazine als antipsychotische mittel. - Google Patents

Heteroaryl piperazine als antipsychotische mittel.

Info

Publication number
ATE113282T1
ATE113282T1 AT90307166T AT90307166T ATE113282T1 AT E113282 T1 ATE113282 T1 AT E113282T1 AT 90307166 T AT90307166 T AT 90307166T AT 90307166 T AT90307166 T AT 90307166T AT E113282 T1 ATE113282 T1 AT E113282T1
Authority
AT
Austria
Prior art keywords
sychotic
agents
heteroaryl piperazines
piperazines
heteroaryl
Prior art date
Application number
AT90307166T
Other languages
English (en)
Inventor
Harry R Howard
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE113282T1 publication Critical patent/ATE113282T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Gas Separation By Absorption (AREA)
  • Treating Waste Gases (AREA)
  • Hydrogenated Pyridines (AREA)
AT90307166T 1989-07-07 1990-06-29 Heteroaryl piperazine als antipsychotische mittel. ATE113282T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1989/002954 WO1991000863A1 (en) 1989-07-07 1989-07-07 Heteroaryl piperazine antipsychotic agents

Publications (1)

Publication Number Publication Date
ATE113282T1 true ATE113282T1 (de) 1994-11-15

Family

ID=22215102

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90307166T ATE113282T1 (de) 1989-07-07 1990-06-29 Heteroaryl piperazine als antipsychotische mittel.

Country Status (11)

Country Link
EP (1) EP0409435B1 (de)
JP (1) JPH0717633B2 (de)
AT (1) ATE113282T1 (de)
CA (1) CA2020611A1 (de)
DE (1) DE69013601T2 (de)
DK (1) DK0409435T3 (de)
ES (1) ES2062374T3 (de)
FI (1) FI920023A0 (de)
IE (1) IE63134B1 (de)
PT (1) PT94608A (de)
WO (1) WO1991000863A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0179063B1 (ko) * 1993-02-04 1999-03-20 사사이 아키라 항정신병 작용을 갖는 화합물
FR2761067B1 (fr) * 1997-03-20 1999-04-23 Synthelabo Derives de quinolein-2-(1h)-one, leur preparation et leur application en therapeutique
OA12923A (en) * 2002-09-17 2006-10-13 Warner Lambert Co Heterocyclic substituted piperazines for the treatment of schizophrenia.
EP1546145A1 (de) * 2002-09-26 2005-06-29 Warner-Lambert Company Llc Heterocyclisch substituierte piperazine zur behandlung von schizophrenie
US7160888B2 (en) * 2003-08-22 2007-01-09 Warner Lambert Company Llc [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia
TWI320783B (en) 2005-04-14 2010-02-21 Otsuka Pharma Co Ltd Heterocyclic compound
EP2591784B1 (de) 2005-05-10 2016-09-14 Intermune, Inc. Pyridin-2-on-Derivate als Modulatoren des Stress-aktivierten Proteinkinase Systems
TWI329641B (en) 2005-08-31 2010-09-01 Otsuka Pharma Co Ltd (benzo[b]thiophen-4-yl)piperazine compounds, pharmaceutical compositions comprising the same, uses of the same and processes for preparing the same
WO2008015516A1 (en) * 2006-07-28 2008-02-07 Pfizer Products Inc. Fused tricyclic heterocycles for the treatment of schizophrenia
EP2094686A1 (de) 2006-09-26 2009-09-02 Glaxo Group Limited 5-{2-[4-(2-methyl-5-chinolinyl)-l-piperidinyl]ethyl}chinolinonderivate als modulatoren des 5ht1a-rezeptors zur behandlung sexueller dysfunktion, kognitiver störungen, psychotischer erkrankungen, angst, depression usw.
US8304413B2 (en) 2008-06-03 2012-11-06 Intermune, Inc. Compounds and methods for treating inflammatory and fibrotic disorders
CA2766088C (en) 2009-06-25 2017-06-13 Alkermes, Inc. Heterocyclic compounds for the treatment of neurological and psychological disorders
CA2766033C (en) 2009-06-25 2016-09-20 Alkermes, Inc. Prodrugs of nh-acidic compounds
EP4327872A2 (de) 2011-03-18 2024-02-28 Alkermes Pharma Ireland Limited Pharmazeutische zusammensetzungen enthaltend sorbitanester
ES2715562T3 (es) 2011-12-15 2019-06-04 Alkermes Pharma Ireland Ltd Profármacos de compuestos de amina secundaria
ES2950418T3 (es) 2012-03-19 2023-10-09 Alkermes Pharma Ireland Ltd Composiciones farmacéuticas que comprenden alcohol bencílico
ES2765036T3 (es) 2012-03-19 2020-06-05 Alkermes Pharma Ireland Ltd Composiciones farmacéuticas que comprenden esteres de ácidos grasos
ES2764383T3 (es) 2012-03-19 2020-06-03 Alkermes Pharma Ireland Ltd Composiciones farmacéuticas que comprenden ésteres de glicerol
WO2014080285A2 (en) 2012-09-19 2014-05-30 Alkermes Pharma Ireland Limited Pharmaceutical compositions having improved storage stability
AR092742A1 (es) 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
US9452131B2 (en) 2014-03-20 2016-09-27 Alkermes Pharma Ireland Limited Aripiprazole formulations having increased injection speeds
JP5714152B2 (ja) * 2014-03-26 2015-05-07 江蘇恒誼薬業有限公司 アラルキルピペリジン（又はピペラジン）誘導体及びその統合失調症治療のための使用
KR102373700B1 (ko) 2014-04-02 2022-03-11 인터뮨, 인크. 항섬유성 피리디논
US11273158B2 (en) 2018-03-05 2022-03-15 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4721721A (en) * 1984-12-18 1988-01-26 Rorer Pharmaceutical Corporation 6-(4-thiazole) compounds, cardiotonic compositions including the same, and their uses
MX173362B (es) * 1987-03-02 1994-02-23 Pfizer Compuestos de piperazinil heterociclicos y procedimiento para su preparacion
ATE81123T1 (de) * 1987-11-20 1992-10-15 Hoechst Roussel Pharma 3-(4(1-substituierte-4-piperazinyl)butyl>-4thiazolidinone, verfahren zu deren herstellung und ihre anwendung als arzneimittel.
US4880930A (en) * 1987-11-30 1989-11-14 New James S Psychotropic acyclic amide derivatives
US4831031A (en) * 1988-01-22 1989-05-16 Pfizer Inc. Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity

Also Published As

Publication number Publication date
JPH0344388A (ja) 1991-02-26
PT94608A (pt) 1991-03-20
IE902450A1 (en) 1991-02-13
EP0409435B1 (de) 1994-10-26
FI920023A0 (fi) 1992-01-03
CA2020611A1 (en) 1991-01-08
EP0409435A1 (de) 1991-01-23
DE69013601D1 (de) 1994-12-01
DE69013601T2 (de) 1995-03-02
ES2062374T3 (es) 1994-12-16
JPH0717633B2 (ja) 1995-03-01
WO1991000863A1 (en) 1991-01-24
IE63134B1 (en) 1995-03-22
DK0409435T3 (da) 1994-11-21

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee