NO953070L - 4-hydroksy-benzopyran-2-oner og 4-hydroksysykloalkyl[BÅpyran-2-oner anvendbare for behandling av retrovirusinfeksjoner - Google Patents

4-hydroksy-benzopyran-2-oner og 4-hydroksysykloalkyl[BÅpyran-2-oner anvendbare for behandling av retrovirusinfeksjoner

Info

Publication number
NO953070L
NO953070L NO953070A NO953070A NO953070L NO 953070 L NO953070 L NO 953070L NO 953070 A NO953070 A NO 953070A NO 953070 A NO953070 A NO 953070A NO 953070 L NO953070 L NO 953070L
Authority
NO
Norway
Prior art keywords
hydroxy
benzopyran
pyran
cycloalkyl
pct
Prior art date
Application number
NO953070A
Other languages
English (en)
Norwegian (no)
Other versions
NO953070D0 (no
Inventor
David John Anderson
Lee S Banitt
Paul Kosta Tomich
Michael John Bohanon
Steven Ronald Turner
Joseph Walter Strohbach
Suvit Thaisrivongs
Chih-Ping Yang
Richard Charles Thomas
Karen Rene Romines
Paul Adrian Aristoff
Harvey Irving Skulnick
Paul D Johnson
Ronald B Gammill
Qingwei Zhang
Gordon L Bundy
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of NO953070D0 publication Critical patent/NO953070D0/no
Publication of NO953070L publication Critical patent/NO953070L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
    • C07D311/56—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 without hydrogen atoms in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO953070A 1993-02-05 1995-08-04 4-hydroksy-benzopyran-2-oner og 4-hydroksysykloalkyl[BÅpyran-2-oner anvendbare for behandling av retrovirusinfeksjoner NO953070L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1445993A 1993-02-05 1993-02-05
US6871593A 1993-05-27 1993-05-27
US16930293A 1993-12-17 1993-12-17
PCT/US1994/000938 WO1994018188A1 (fr) 1993-02-05 1994-02-03 4-hydroxy-benzopyrane-2-ones et 4-hydroxy-cycloalkyle-[b]pyrane-2-ones utiles pour le traitement des infections retrovirales

Publications (2)

Publication Number Publication Date
NO953070D0 NO953070D0 (no) 1995-08-04
NO953070L true NO953070L (no) 1995-10-04

Family

ID=27360109

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953070A NO953070L (no) 1993-02-05 1995-08-04 4-hydroksy-benzopyran-2-oner og 4-hydroksysykloalkyl[BÅpyran-2-oner anvendbare for behandling av retrovirusinfeksjoner

Country Status (22)

Country Link
US (1) US5686486A (fr)
EP (1) EP0682663B1 (fr)
JP (2) JPH08505641A (fr)
CN (1) CN1117291A (fr)
AT (1) ATE200669T1 (fr)
AU (1) AU6166194A (fr)
CA (1) CA2153237A1 (fr)
CZ (1) CZ9502002A3 (fr)
DE (1) DE69427120T2 (fr)
DK (1) DK0682663T3 (fr)
FI (1) FI953717A0 (fr)
GR (1) GR3036189T3 (fr)
HU (1) HUT72755A (fr)
IL (1) IL108459A0 (fr)
LV (1) LV12863B (fr)
NO (1) NO953070L (fr)
NZ (1) NZ262255A (fr)
PL (1) PL310111A1 (fr)
PT (1) PT682663E (fr)
RU (1) RU2125999C1 (fr)
SK (1) SK95695A3 (fr)
WO (1) WO1994018188A1 (fr)

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US6319929B1 (en) 1994-04-29 2001-11-20 The University Of North Carolina At Chapel Hill Suksdorfin analogs, compositions thereof, and methods for making and using thereof
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AU5417696A (en) * 1995-03-20 1996-10-08 Upjohn Company, The Substituted tetronic acids useful for treating hiv and other retroviruses
US6037157A (en) 1995-06-29 2000-03-14 Abbott Laboratories Method for improving pharmacokinetics
CA2222471A1 (fr) * 1996-03-27 1997-10-02 Toray Industries, Inc. Derives de cetone et utilisation medicale connexe
US6410777B1 (en) * 1997-04-04 2002-06-25 Teijin Limited Salicylic acid ester derivative and its production
DE69833952T2 (de) * 1997-09-26 2006-12-07 Toray Industries, Inc. Zyklische ketonderivate und ihre pharmazeutische verwendung
US7145020B2 (en) * 2001-04-24 2006-12-05 Aryx Therapeutics Materials and methods for treating coagulation disorders
ATE388143T1 (de) * 2001-04-24 2008-03-15 Aryx Therapeutics Cumarin derivate und ihre verwendung als anticoagulantien
WO2002088298A1 (fr) * 2001-04-27 2002-11-07 The Procter & Gamble Company Composes, compositions et procedes permettant de reguler des films biologiques
US7202928B2 (en) * 2003-10-16 2007-04-10 Lg. Philips Lcd Co., Ltd Array substrate for in-plane switching mode liquid crystal display device and method of fabricating the same
BRPI0508392A (pt) * 2004-04-08 2007-08-07 Aryx Therapeutics materiais e métodos para tratar distúrbios de coagulação
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AR059339A1 (es) * 2006-02-09 2008-03-26 Chugai Pharmaceutical Co Ltd Derivados de la cumarina para trastornos proliferativos de celulas, composicion farmaceutica y agente terapeutico que los contiene
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CA2705318C (fr) * 2007-11-15 2013-12-31 Boehringer Ingelheim International Gmbh Inhibiteurs de la replication du virus de l'immunodeficience humaine
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EP2379504A2 (fr) * 2008-12-22 2011-10-26 Sloan Kettering Institute For Cancer Research Composés à base de coumarine
CN102040592B (zh) * 2009-10-10 2015-07-15 西南大学 具有抗微生物活性的香豆素唑类化合物、制备方法和医药用途
EP2928459A4 (fr) * 2012-12-06 2016-10-26 Baruch S Blumberg Inst Dérivés fonctionnalisés de benzamide en tant qu'agents antiviraux contre une infection à vhb
US9487485B2 (en) 2013-02-28 2016-11-08 Takeda Pharmaceutical Company Limited Method for producing sulfonyl chloride compound
EP2970037A4 (fr) 2013-03-15 2016-10-26 Micromidas Inc Procédés de préparation d'alkylfurannes
EA032713B1 (ru) * 2013-12-30 2019-07-31 Лайфсай Фармасьютикалс, Инк. Терапевтические ингибирующие соединения
WO2016040527A1 (fr) * 2014-09-09 2016-03-17 Vanderbilt University Sondes du métabolisme pour la thérapie et le diagnostic
CN104374858B (zh) * 2014-11-21 2016-06-29 宜昌人福药业有限责任公司 一种枸橼酸舒芬太尼合成原料及杂质的检测方法
CN105218530B (zh) * 2015-10-20 2019-07-02 青岛农业大学 3-(1-芳基-2-(2-氮杂芳烃)乙基)-4-羟基香豆素及其制备方法
CN109608421A (zh) * 2019-01-22 2019-04-12 河北科技大学 一种5-氨基酮戊酸盐酸盐的合成方法
RU2707103C1 (ru) * 2019-06-15 2019-11-22 Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр "КОМИ научный центр Уральского отделения Российской академии наук" Кумарины с бициклическими монотерпеновыми заместителями
WO2021158575A1 (fr) * 2020-02-03 2021-08-12 Natural Extraction Systems, LLC Compositions associées à des agents bioactifs qui convertissent des anions en molécules
WO2022182523A1 (fr) * 2021-02-26 2022-09-01 Natural Extraction Systems, LLC Compositions associées à des agents bioactifs qui convertissent des anions en molécules

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Also Published As

Publication number Publication date
CZ9502002A3 (en) 1995-12-13
HUT72755A (en) 1996-05-28
AU6166194A (en) 1994-08-29
CA2153237A1 (fr) 1994-08-18
FI953717A (fi) 1995-08-04
DK0682663T3 (da) 2001-06-18
US5686486A (en) 1997-11-11
CN1117291A (zh) 1996-02-21
NZ262255A (en) 1997-05-26
JPH08505641A (ja) 1996-06-18
ATE200669T1 (de) 2001-05-15
DE69427120T2 (de) 2001-08-23
GR3036189T3 (en) 2001-10-31
IL108459A0 (en) 1994-04-12
JP2005002133A (ja) 2005-01-06
RU2125999C1 (ru) 1999-02-10
WO1994018188A1 (fr) 1994-08-18
EP0682663A1 (fr) 1995-11-22
DE69427120D1 (de) 2001-05-23
NO953070D0 (no) 1995-08-04
HU9501968D0 (en) 1995-09-28
EP0682663B1 (fr) 2001-04-18
LV12863B (en) 2002-11-20
FI953717A0 (fi) 1995-08-04
SK95695A3 (en) 1995-12-06
PT682663E (pt) 2001-10-30
PL310111A1 (en) 1995-11-27

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