NO941186L - Hormonanaloger med multiple CTP-forlengelser - Google Patents

Hormonanaloger med multiple CTP-forlengelser

Info

Publication number
NO941186L
NO941186L NO941186A NO941186A NO941186L NO 941186 L NO941186 L NO 941186L NO 941186 A NO941186 A NO 941186A NO 941186 A NO941186 A NO 941186A NO 941186 L NO941186 L NO 941186L
Authority
NO
Norway
Prior art keywords
amino acid
ctp units
partial
complete
hormone analogues
Prior art date
Application number
NO941186A
Other languages
English (en)
Other versions
NO941186D0 (no
Inventor
Irving Boime
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington filed Critical Univ Washington
Publication of NO941186D0 publication Critical patent/NO941186D0/no
Publication of NO941186L publication Critical patent/NO941186L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/11—Gonadotropin; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/141—Interleukin

Abstract

Oppfinnelsen tilveiebringer peptid- og proteinfamasøytika med forlengede halveringstider. De modifiserte peptider og proteiner ifølge oppfinnelsen inneholder minst to tandemforlengelser ved sin C-ende omfattende den karboksyterminale del av humant korionisk gonadotropin. Disse "CTP- enheter" består vesentlig av den naturlige HCG-/3-sekvens fra posisjon 112-118 til posisjon 145 eller konservative modifika- sjoner derav.
NO941186A 1991-10-04 1994-03-30 Hormonanaloger med multiple CTP-forlengelser NO941186L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/771,262 US6225449B1 (en) 1991-10-04 1991-10-04 Hormone analogs with multiple CTP extensions
PCT/US1992/008424 WO1993006844A1 (en) 1991-10-04 1992-10-02 Hormone analogs with multiple ctp extensions

Publications (2)

Publication Number Publication Date
NO941186D0 NO941186D0 (no) 1994-03-30
NO941186L true NO941186L (no) 1994-03-30

Family

ID=25091246

Family Applications (1)

Application Number Title Priority Date Filing Date
NO941186A NO941186L (no) 1991-10-04 1994-03-30 Hormonanaloger med multiple CTP-forlengelser

Country Status (11)

Country Link
US (2) US6225449B1 (no)
EP (1) EP0607297B1 (no)
JP (2) JP4081137B2 (no)
KR (1) KR100281811B1 (no)
AT (1) ATE248922T1 (no)
CA (1) CA2120358A1 (no)
DE (1) DE69233188T2 (no)
ES (1) ES2204893T3 (no)
FI (1) FI941500A (no)
NO (1) NO941186L (no)
WO (1) WO1993006844A1 (no)

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Also Published As

Publication number Publication date
DE69233188T2 (de) 2004-05-27
CA2120358A1 (en) 1993-04-15
ES2204893T3 (es) 2004-05-01
EP0607297B1 (en) 2003-09-03
FI941500A (fi) 1994-05-23
NO941186D0 (no) 1994-03-30
JP4081137B2 (ja) 2008-04-23
US6225449B1 (en) 2001-05-01
KR100281811B1 (ko) 2001-02-15
EP0607297A4 (en) 1995-10-25
WO1993006844A1 (en) 1993-04-15
ATE248922T1 (de) 2003-09-15
AU667489B2 (en) 1996-03-28
US5759818A (en) 1998-06-02
EP0607297A1 (en) 1994-07-27
DE69233188D1 (de) 2003-10-09
AU2864892A (en) 1993-05-03
FI941500A0 (fi) 1994-03-30
JP2008073057A (ja) 2008-04-03
JPH07502166A (ja) 1995-03-09

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