ATE248922T1 - Hormonanaloge mit mehreren ctp-erweiterungen - Google Patents

Hormonanaloge mit mehreren ctp-erweiterungen

Info

Publication number
ATE248922T1
ATE248922T1 AT92921759T AT92921759T ATE248922T1 AT E248922 T1 ATE248922 T1 AT E248922T1 AT 92921759 T AT92921759 T AT 92921759T AT 92921759 T AT92921759 T AT 92921759T AT E248922 T1 ATE248922 T1 AT E248922T1
Authority
AT
Austria
Prior art keywords
amino acid
ctp units
partial
complete
hormone analogues
Prior art date
Application number
AT92921759T
Other languages
English (en)
Inventor
Irving Boime
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington filed Critical Univ Washington
Application granted granted Critical
Publication of ATE248922T1 publication Critical patent/ATE248922T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/11—Gonadotropin; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/141—Interleukin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT92921759T 1991-10-04 1992-10-02 Hormonanaloge mit mehreren ctp-erweiterungen ATE248922T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/771,262 US6225449B1 (en) 1991-10-04 1991-10-04 Hormone analogs with multiple CTP extensions
PCT/US1992/008424 WO1993006844A1 (en) 1991-10-04 1992-10-02 Hormone analogs with multiple ctp extensions

Publications (1)

Publication Number Publication Date
ATE248922T1 true ATE248922T1 (de) 2003-09-15

Family

ID=25091246

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92921759T ATE248922T1 (de) 1991-10-04 1992-10-02 Hormonanaloge mit mehreren ctp-erweiterungen

Country Status (11)

Country Link
US (2) US6225449B1 (de)
EP (1) EP0607297B1 (de)
JP (2) JP4081137B2 (de)
KR (1) KR100281811B1 (de)
AT (1) ATE248922T1 (de)
CA (1) CA2120358A1 (de)
DE (1) DE69233188T2 (de)
ES (1) ES2204893T3 (de)
FI (1) FI941500A (de)
NO (1) NO941186D0 (de)
WO (1) WO1993006844A1 (de)

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EP0461200B1 (de) 1989-02-21 1997-01-22 Washington University Modifizierte formen von fortpflanzungshormonen
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ES2141229T3 (es) * 1993-04-20 2000-03-16 Univ Washington Productos farmaceuticos de proteinas y peptidos modificados.
US6737515B2 (en) 1993-11-19 2004-05-18 Washington University Follicle stimulating hormone-glycosylation analogs
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ATE295887T1 (de) * 1996-02-20 2005-06-15 Applied Research Systems Heterodimerebildende hybrid-proteine
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US20030036181A1 (en) * 2000-06-30 2003-02-20 Okkels Jens Sigurd Peptide extended glycosylated polypeptides
WO2002048194A1 (en) * 2000-12-11 2002-06-20 Cheil Jedang Corporation Fusion protein having the enhanced in vivo activity of erythropoietin
KR101229995B1 (ko) * 2000-12-11 2013-02-06 씨제이 주식회사 생체내 에리스로포이에틴 활성이 증진된 융합단백질
US6987172B2 (en) * 2001-03-05 2006-01-17 Washington University In St. Louis Multifunctional single chain glycoprotein hormones comprising three or more β subunits
CA2464368A1 (en) * 2001-10-22 2003-05-01 Applied Research Systems Ars Holding N.V. Compositions of fsh with high sialylation degree and their use for the preparation of medicaments
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US7173113B2 (en) * 2002-01-31 2007-02-06 The Trustees Of Columbia University In The City Of New York Long-acting hormone and growth factor compositions and uses thereof
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US20150038413A1 (en) 2006-02-03 2015-02-05 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
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Also Published As

Publication number Publication date
US5759818A (en) 1998-06-02
JP2008073057A (ja) 2008-04-03
DE69233188T2 (de) 2004-05-27
AU667489B2 (en) 1996-03-28
EP0607297A1 (de) 1994-07-27
AU2864892A (en) 1993-05-03
KR100281811B1 (ko) 2001-02-15
EP0607297A4 (en) 1995-10-25
US6225449B1 (en) 2001-05-01
FI941500A0 (fi) 1994-03-30
DE69233188D1 (de) 2003-10-09
JPH07502166A (ja) 1995-03-09
NO941186L (no) 1994-03-30
WO1993006844A1 (en) 1993-04-15
CA2120358A1 (en) 1993-04-15
ES2204893T3 (es) 2004-05-01
NO941186D0 (no) 1994-03-30
EP0607297B1 (de) 2003-09-03
FI941500A (fi) 1994-05-23
JP4081137B2 (ja) 2008-04-23

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