NO940676L - - Google Patents
Info
- Publication number
- NO940676L NO940676L NO940676A NO940676A NO940676L NO 940676 L NO940676 L NO 940676L NO 940676 A NO940676 A NO 940676A NO 940676 A NO940676 A NO 940676A NO 940676 L NO940676 L NO 940676L
- Authority
- NO
- Norway
- Prior art keywords
- cyclic
- branched
- alkyl
- hydrogen
- straight
- Prior art date
Links
- 125000004122 cyclic group Chemical group 0.000 abstract 5
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- OZDAOHVKBFBBMZ-UHFFFAOYSA-N 2-aminopentanedioic acid;hydrate Chemical compound O.OC(=O)C(N)CCC(O)=O OZDAOHVKBFBBMZ-UHFFFAOYSA-N 0.000 abstract 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 108010011562 aspartic acid receptor Proteins 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 235000013922 glutamic acid Nutrition 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75116591A | 1991-08-28 | 1991-08-28 | |
| US83185192A | 1992-02-05 | 1992-02-05 | |
| PCT/EP1992/001999 WO1993005043A1 (en) | 1991-08-28 | 1992-08-27 | Novel isatinoxime derivatives, their preparation and use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO940676D0 NO940676D0 (no) | 1994-02-25 |
| NO940676L true NO940676L (enExample) | 1994-04-27 |
| NO301117B1 NO301117B1 (no) | 1997-09-15 |
Family
ID=27115380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO940676A NO301117B1 (no) | 1991-08-28 | 1994-02-25 | Nye isatinoksimderivater, farmasöytiske preparater som inneholder en slik forbindelse, samt anvendelse og en fremgangsmåte for fremstilling av slike forbindelser |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0529636B1 (enExample) |
| JP (1) | JP3170584B2 (enExample) |
| KR (1) | KR100277481B1 (enExample) |
| AT (1) | ATE181552T1 (enExample) |
| AU (1) | AU655672B2 (enExample) |
| CA (1) | CA2076948C (enExample) |
| CZ (1) | CZ282759B6 (enExample) |
| DE (1) | DE69229461T2 (enExample) |
| DK (1) | DK0529636T3 (enExample) |
| FI (1) | FI107156B (enExample) |
| GE (1) | GEP20002329B (enExample) |
| HU (2) | HUT70753A (enExample) |
| MX (1) | MX9204914A (enExample) |
| NO (1) | NO301117B1 (enExample) |
| PL (1) | PL170920B1 (enExample) |
| RU (1) | RU2114827C1 (enExample) |
| SK (1) | SK280578B6 (enExample) |
| WO (1) | WO1993005043A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08502483A (ja) | 1992-10-13 | 1996-03-19 | ワーナー−ランバート・コンパニー | 新規なキノキサリンジオン誘導体、それらの製造および使用 |
| US5843945A (en) * | 1993-05-13 | 1998-12-01 | Neurosearch A/S | AMPA antagonists and a method of treatment |
| FI954965L (fi) * | 1993-05-13 | 1995-11-10 | Neurosearch As | AMPA-antagonisteja ja hoitomenetelmä, jossa niitä käytetään |
| DK81593D0 (da) * | 1993-07-07 | 1993-07-07 | Neurosearch As | Nye isatinoximderivater, deres fremstilling og anvendelse |
| EP0781285B1 (en) * | 1994-09-14 | 2000-01-12 | Neurosearch A/S | Fused indole and quinoxaline derivatives, their preparation and use as glutamate antagonists |
| CA2199613C (en) * | 1994-09-14 | 2000-02-29 | Peter Moldt | Indole-2,3-dione-3-oxime derivatives, their preparation and use |
| UA54403C2 (uk) * | 1996-10-01 | 2003-03-17 | Н'Юросерч А/С | Похідні індол-2,3-діон-3-оксиму, фармацевтична композиція, спосіб лікування розладу чи захворювання ссавців, у тому числі людини та спосіб одержання похідних індол-2,3-діон-3-оксиму |
| FR2768624B1 (fr) * | 1997-09-25 | 1999-11-12 | Oreal | Utilisation d'un inhibiteur d'acides amines excitateurs dans une composition cosmetique ou dermatologique pour peaux sensibles et composition obtenue |
| DE60041399D1 (de) | 1999-05-19 | 2009-03-05 | Painceptor Pharma Corp | Hemmer der protonenabhängigen kationenkanäle und deren verwendung in der behandlung von ischemiebedingten erkrankungen |
| EP1736468A3 (en) | 2000-01-24 | 2007-01-03 | NeuroSearch A/S | Isatin derivatives with neurotrophic activity useful in the treatment of diseases mediated by the nerve growth factor (NGF) activation |
| WO2004039372A1 (en) | 2002-10-29 | 2004-05-13 | Sungkyunkwan University | Medicament component of berberine for the use of prevention and treatment of psycological dependence on and analgesic tolerance to morphine |
| EP1957486A4 (en) | 2005-11-23 | 2009-11-11 | Painceptor Pharma Corp | COMPOSITIONS AND METHODS FOR MODULATION OF IONIC CHANNELS |
| WO2014095675A1 (en) | 2012-12-19 | 2014-06-26 | Bayer Cropscience Ag | Difluoromethyl-nicotinic-indanyl carboxamides as fungicides |
| US9815768B2 (en) * | 2014-02-28 | 2017-11-14 | Sumitomo Chemical Company, Limited | Method for producing 2-(halogenomethyl)-3-methylnitrobenzene |
| HUE055651T2 (hu) | 2016-03-17 | 2021-12-28 | Fmc Corp | Eljárás S-enantiomer konvertálására racém formájává |
| CN112266368B (zh) * | 2017-11-15 | 2024-03-19 | 中山光禾医疗科技有限公司 | 光交联水凝胶材料的制备、原料、产品及应用 |
| CN108912127B (zh) * | 2018-08-27 | 2019-12-10 | 青岛农业大学 | 一种基于靛红骨架的苯并[b,e]氮杂卓化合物及其制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE69677B1 (en) * | 1989-12-11 | 1996-10-02 | Neurosearch As | Isatine derivatives their preparation and use |
-
1992
- 1992-08-26 MX MX9204914A patent/MX9204914A/es not_active IP Right Cessation
- 1992-08-26 CA CA002076948A patent/CA2076948C/en not_active Expired - Fee Related
- 1992-08-27 KR KR1019940700676A patent/KR100277481B1/ko not_active Expired - Fee Related
- 1992-08-27 AU AU24820/92A patent/AU655672B2/en not_active Ceased
- 1992-08-27 JP JP50493393A patent/JP3170584B2/ja not_active Expired - Fee Related
- 1992-08-27 CZ CZ94395A patent/CZ282759B6/cs not_active IP Right Cessation
- 1992-08-27 SK SK238-94A patent/SK280578B6/sk unknown
- 1992-08-27 PL PL92302584A patent/PL170920B1/pl unknown
- 1992-08-27 GE GEAP19922683A patent/GEP20002329B/en unknown
- 1992-08-27 EP EP92114654A patent/EP0529636B1/en not_active Expired - Lifetime
- 1992-08-27 WO PCT/EP1992/001999 patent/WO1993005043A1/en not_active Ceased
- 1992-08-27 RU RU94019425/04A patent/RU2114827C1/ru not_active IP Right Cessation
- 1992-08-27 AT AT92114654T patent/ATE181552T1/de not_active IP Right Cessation
- 1992-08-27 DE DE69229461T patent/DE69229461T2/de not_active Expired - Lifetime
- 1992-08-27 HU HU9400595A patent/HUT70753A/hu unknown
- 1992-08-27 DK DK92114654T patent/DK0529636T3/da active
-
1994
- 1994-02-25 FI FI940889A patent/FI107156B/fi active
- 1994-02-25 NO NO940676A patent/NO301117B1/no unknown
-
1995
- 1995-06-21 HU HU95P/P00323P patent/HU211632A9/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1993005043A1 (en) | 1993-03-18 |
| AU655672B2 (en) | 1995-01-05 |
| FI107156B (fi) | 2001-06-15 |
| EP0529636A1 (en) | 1993-03-03 |
| FI940889A7 (fi) | 1994-02-25 |
| CZ39594A3 (en) | 1994-11-16 |
| NO940676D0 (no) | 1994-02-25 |
| SK23894A3 (en) | 1994-12-07 |
| NO301117B1 (no) | 1997-09-15 |
| MX9204914A (es) | 1993-07-01 |
| GEP20002329B (en) | 2000-12-25 |
| HU9400595D0 (en) | 1994-05-30 |
| DE69229461T2 (de) | 1999-10-21 |
| SK280578B6 (sk) | 2000-04-10 |
| JPH06510056A (ja) | 1994-11-10 |
| DK0529636T3 (da) | 1999-12-13 |
| RU2114827C1 (ru) | 1998-07-10 |
| CA2076948C (en) | 2002-04-16 |
| HUT70753A (en) | 1995-10-30 |
| FI940889A0 (fi) | 1994-02-25 |
| DE69229461D1 (de) | 1999-07-29 |
| HU211632A9 (en) | 1995-12-28 |
| AU2482092A (en) | 1993-04-05 |
| ATE181552T1 (de) | 1999-07-15 |
| JP3170584B2 (ja) | 2001-05-28 |
| PL170920B1 (pl) | 1997-02-28 |
| CA2076948A1 (en) | 1993-03-01 |
| EP0529636B1 (en) | 1999-06-23 |
| CZ282759B6 (cs) | 1997-09-17 |
| KR100277481B1 (ko) | 2001-02-01 |
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