NO934146L - Nye derivater av tiopyranopyrrol, deres fremstilling og farmasoeytiske preparater inneholdende forbindelsene - Google Patents

Nye derivater av tiopyranopyrrol, deres fremstilling og farmasoeytiske preparater inneholdende forbindelsene

Info

Publication number
NO934146L
NO934146L NO934146A NO934146A NO934146L NO 934146 L NO934146 L NO 934146L NO 934146 A NO934146 A NO 934146A NO 934146 A NO934146 A NO 934146A NO 934146 L NO934146 L NO 934146L
Authority
NO
Norway
Prior art keywords
thiopyranopyrrole
compounds
preparation
pharmaceutical preparations
preparations containing
Prior art date
Application number
NO934146A
Other languages
English (en)
Norwegian (no)
Other versions
NO934146D0 (no
Inventor
Daniel Achard
Claude Moutonnier
Jean-Francois Peyronel
Michel Tabart
Alain Truchon
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of NO934146D0 publication Critical patent/NO934146D0/no
Publication of NO934146L publication Critical patent/NO934146L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO934146A 1991-05-17 1993-11-16 Nye derivater av tiopyranopyrrol, deres fremstilling og farmasoeytiske preparater inneholdende forbindelsene NO934146L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9106037A FR2676446B1 (fr) 1991-05-17 1991-05-17 Nouveaux derives du thiopyranopyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent.
PCT/FR1992/000431 WO1992020685A1 (fr) 1991-05-17 1992-05-15 Nouveaux derives du thiopyranopyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
NO934146D0 NO934146D0 (no) 1993-11-16
NO934146L true NO934146L (no) 1993-11-16

Family

ID=9412909

Family Applications (1)

Application Number Title Priority Date Filing Date
NO934146A NO934146L (no) 1991-05-17 1993-11-16 Nye derivater av tiopyranopyrrol, deres fremstilling og farmasoeytiske preparater inneholdende forbindelsene

Country Status (17)

Country Link
EP (2) EP0514275A1 (fi)
JP (1) JPH06507894A (fi)
AU (1) AU653033B2 (fi)
CA (1) CA2109296A1 (fi)
CZ (1) CZ244993A3 (fi)
FI (1) FI935073A (fi)
FR (1) FR2676446B1 (fi)
HU (1) HUT70490A (fi)
IE (1) IE921543A1 (fi)
IL (1) IL101864A0 (fi)
MX (1) MX9202289A (fi)
NO (1) NO934146L (fi)
NZ (1) NZ242737A (fi)
SK (1) SK126993A3 (fi)
TW (1) TW201748B (fi)
WO (1) WO1992020685A1 (fi)
ZA (1) ZA923513B (fi)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2676447B1 (fr) * 1991-05-17 1993-08-06 Rhone Poulenc Rorer Sa Nouveaux derives du thiopyranopyrrole et leur preparation.
FR2725900B1 (fr) * 1994-10-21 1997-07-18 Sanofi Sa Utilisation d'antagonistes des recepteurs nk1 pour la preparation de medicaments a action cardioregulatrice
FR2728169A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
FR2728166A1 (fr) 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
FR2728165A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
FR2733750B1 (fr) * 1995-05-03 1997-06-13 Synthelabo Derives de l'acide gamma-oxo-alpha-(phenylmethyl)-5,6- dihydro-4h-thieno(3,4-c)pyrrole-5-butanoique, leur preparation et leur application en therapeutique
FR2741262B1 (fr) 1995-11-20 1999-03-05 Oreal Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene
FR2777566B1 (fr) * 1998-04-15 2003-02-21 Synthelabo Derives d'azacycloalcanes, leur preparation et leur application en therapeutique
US7163949B1 (en) 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
EP1246806B1 (en) 1999-11-03 2008-02-27 AMR Technology, Inc. Arly- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
WO2002004455A2 (en) 2000-07-11 2002-01-17 Albany Molecular Research, Inc 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
KR101389246B1 (ko) 2004-07-15 2014-04-24 브리스톨-마이어스스퀴브컴파니 아릴- 및 헤테로아릴-치환된 테트라히드로이소퀴놀린, 및 이것의 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 용도
US8362075B2 (en) 2005-05-17 2013-01-29 Merck Sharp & Dohme Corp. Cyclohexyl sulphones for treatment of cancer
KR101594898B1 (ko) 2005-07-15 2016-02-18 알바니 몰레큘라 리써치, 인크. 아릴- 및 헤테로아릴-치환된 테트라히드로벤자제핀, 및 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 용도
GB0603041D0 (en) 2006-02-15 2006-03-29 Angeletti P Ist Richerche Bio Therapeutic compounds
US20110218176A1 (en) 2006-11-01 2011-09-08 Barbara Brooke Jennings-Spring Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
GEP20115337B (en) 2007-01-10 2011-11-25 St Di Ricerche Di Biologia Molecolare P Angeletti Spa Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
EP2117538A1 (en) 2007-01-24 2009-11-18 Glaxo Group Limited Pharmaceutical compositions comprising 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-)
US8389553B2 (en) 2007-06-27 2013-03-05 Merck Sharp & Dohme Corp. 4-carboxybenzylamino derivatives as histone deacetylase inhibitors
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
UA105182C2 (ru) 2008-07-03 2014-04-25 Ньюрексон, Інк. Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность
WO2010114780A1 (en) 2009-04-01 2010-10-07 Merck Sharp & Dohme Corp. Inhibitors of akt activity
EA020553B1 (ru) 2009-05-12 2014-12-30 Олбани Молекьюлар Рисерч, Инк. 7-([1,2,4]ТРИАЗОЛО[1,5-α]ПИРИДИН-6-ИЛ)-4-(3,4-ДИХЛОРФЕНИЛ)-1,2,3,4-ТЕТРАГИДРОИЗОХИНОЛИН, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ЕГО ОСНОВЕ И СПОСОБЫ ЛЕЧЕНИЯ НЕВРОЛОГИЧЕСКИХ И ПСИХИЧЕСКИХ РАССТРОЙСТВ
WO2010132437A1 (en) 2009-05-12 2010-11-18 Albany Molecular Research, Inc. Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof
JP5739415B2 (ja) 2009-05-12 2015-06-24 ブリストル−マイヤーズ スクウィブ カンパニー （Ｓ）−７−（［１，２，４］トリアゾロ［１，５−ａ］ピリジン−６−イル）−４−（３，４−ジクロロフェニル）−１，２，３，４−テトラヒドロイソキノリンの結晶形態およびその使用
MX2012004377A (es) 2009-10-14 2012-06-01 Merck Sharp & Dohme Piperidinas sustituidas que aumentan la actividad de p53 y sus usos.
EP2601293B1 (en) 2010-08-02 2017-12-06 Sirna Therapeutics, Inc. RNA INTERFERENCE MEDIATED INHIBITION OF CATENIN (CADHERIN-ASSOCIATED PROTEIN), BETA 1 (CTNNB1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
AU2011292261B2 (en) 2010-08-17 2015-05-14 Sirna Therapeutics, Inc. RNA interference mediated inhibition of Hepatitis B virus (HBV) gene expression using short interfering nucleic acid (siNA)
EP2608669B1 (en) 2010-08-23 2016-06-22 Merck Sharp & Dohme Corp. NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS
EP2613782B1 (en) 2010-09-01 2016-11-02 Merck Sharp & Dohme Corp. Indazole derivatives useful as erk inhibitors
EP2615916B1 (en) 2010-09-16 2017-01-04 Merck Sharp & Dohme Corp. Fused pyrazole derivatives as novel erk inhibitors
EP3327125B1 (en) 2010-10-29 2020-08-05 Sirna Therapeutics, Inc. Rna interference mediated inhibition of gene expression using short interfering nucleic acids (sina)
WO2012087772A1 (en) 2010-12-21 2012-06-28 Schering Corporation Indazole derivatives useful as erk inhibitors
US20140045832A1 (en) 2011-04-21 2014-02-13 Piramal Enterprises Limited Insulin-Like Growth Factor-1 Receptor Inhibitors
WO2013063214A1 (en) 2011-10-27 2013-05-02 Merck Sharp & Dohme Corp. Novel compounds that are erk inhibitors
EP3453762B1 (en) 2012-05-02 2021-04-21 Sirna Therapeutics, Inc. Short interfering nucleic acid (sina) compositions
MX2015004041A (es) 2012-09-28 2015-07-06 Merck Sharp & Dohme Compuestos novedosos que son inhibidores de erk.
RU2660349C2 (ru) 2012-11-28 2018-07-05 Мерк Шарп И Доум Корп. Композиции и способы для лечения злокачественной опухоли
US8846657B2 (en) 2012-12-20 2014-09-30 Merck Sharp & Dohme Corp. Substituted imidazopyridines as HDM2 inhibitors
EP2951180B1 (en) 2013-01-30 2018-05-02 Merck Sharp & Dohme Corp. 2,6,7,8 substituted purines as hdm2 inhibitors
CN103317438B (zh) * 2013-06-18 2015-08-19 浙江工业大学 动压浮离抛光盘动压浮离位置精密调整机构
WO2015034925A1 (en) 2013-09-03 2015-03-12 Moderna Therapeutics, Inc. Circular polynucleotides
EP3706742B1 (en) 2017-11-08 2023-03-15 Merck Sharp & Dohme LLC Prmt5 inhibitors
WO2020033284A1 (en) 2018-08-07 2020-02-13 Merck Sharp & Dohme Corp. Prmt5 inhibitors
US11993602B2 (en) 2018-08-07 2024-05-28 Merck Sharp & Dohme Llc PRMT5 inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4042707A (en) * 1976-02-19 1977-08-16 E. I. Du Pont De Nemours And Company 3α-Arylhydroisoindoles
EP0058567B1 (en) * 1981-02-17 1984-07-25 Warner-Lambert Company Substituted acyl derivatives of octahydro-1h-isoindole-1-carboxylic acids and esters
US4439229A (en) * 1981-06-29 1984-03-27 Rohm And Haas Company Substituted phthalimides herbicides
FR2676447B1 (fr) * 1991-05-17 1993-08-06 Rhone Poulenc Rorer Sa Nouveaux derives du thiopyranopyrrole et leur preparation.

Also Published As

Publication number Publication date
CA2109296A1 (fr) 1992-11-18
NO934146D0 (no) 1993-11-16
AU653033B2 (en) 1994-09-15
ZA923513B (en) 1993-02-24
AU1914092A (en) 1992-12-30
NZ242737A (en) 1993-06-25
FI935073A0 (fi) 1993-11-16
WO1992020685A1 (fr) 1992-11-26
EP0514275A1 (fr) 1992-11-19
CZ244993A3 (en) 1994-03-16
SK126993A3 (en) 1994-11-09
IE921543A1 (en) 1992-11-18
FR2676446B1 (fr) 1993-08-06
MX9202289A (es) 1993-02-01
HU9303252D0 (en) 1994-03-28
IL101864A0 (en) 1992-12-30
JPH06507894A (ja) 1994-09-08
HUT70490A (en) 1995-10-30
FR2676446A1 (fr) 1992-11-20
TW201748B (fi) 1993-03-11
EP0586486A1 (fr) 1994-03-16
FI935073A (fi) 1993-11-16

Similar Documents

Publication Publication Date Title
NO934146L (no) Nye derivater av tiopyranopyrrol, deres fremstilling og farmasoeytiske preparater inneholdende forbindelsene
NO934723L (no) Nye derivater av taksolanaloger, deres fremstilling og preparater inneholdende derivatene
FI942181A0 (fi) Uudet lupaanijohdannaiset, niiden valmistus ja niitä sisältävät farmaseuttiset valmisteet
NO922940D0 (no) Fem-leddete heterocykliske forbindelser, fremgangsmaate for deres fremstilling og legemidler inneholdende dem
NO933690L (no) Nye tiopyranopyrrolderivater og deres fremstilling
NO900276D0 (no) Nye benzopyranderivater, deres fremstilling og anvendelsei farmasoeytiske preparater.
EE9400455A (et) Peptiidi derivaadid, nende valmistamise protsess, neid sisaldavad ravimpreparaadid ja nende kasutamine
NO952677D0 (no) Nye dihydropyrrolopyridinon- og oksazolopyridinonforbindelser, deres fremstilling og farmasöytiske preparater
NO894539D0 (no) Fremgangsmaate for fremstilling av nye 2'-halomethyliden-,2'-ethenyliden- og 2'-ethynylcytidin-, uriden og guanosinderivater.
DK162491D0 (da) Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne
NO951283D0 (no) Nye taxanderivater, deres fremstilling samt farmasöytiske preparater inneholdende derivatene
NO860857L (no) Nye oksadiazolyl-imidazobenzodiazepin-derivater og fremgangsmaate for fremstilling av slike forbindelser.
DK635988A (da) 1,3-butandiolacetoacetat-derivater og anvendelse af 1,3-butandiolacetoacetat-forbindelser til fremstilling af farmaceutiske praeparater
NO932129D0 (no) Fremgangsmaate for fremstilling og anvendelse av nye tienotiazinderivater
NO922358D0 (no) Tert.-butylfenyl-1-amino-4-hydroksybutanderivater, fremgangsmaate ved deres fremstilling og farmasoeytiske preparaterinneholdende forbindelsene
DK269289D0 (da) Cyklopentanderivater og farmaceutiske praeparater indeholdende saadanne forbindelser
NO921908D0 (no) Aminosyreazetidinylsubstituerte pyridonderivater, deres fremstilling og anvendelse som medikamenter
NO902473D0 (no) Nye pyridobenzoindolderivater, deres fremstilling og preparater inneholdende forbindelsene.
DK463189A (da) 1,4-dihydropyridin-derivater, farmaceutiske praeparater indeholdende disse og deres anvendelse til fremstilling af antiallergiske og antiinflammatoriske laegemidler
NO942181D0 (no) Nye, substituerte oksazinoisokinolinderivater, farmasöytiske preparater inneholdende disse og fremgangsmåte for fremstilling av disse
NO893291D0 (no) Fremgangsmaate for fremstilling av nye benzasolderivater og farmasoeytiske preparater derav.
NO901239D0 (no) Nye platinakompleksderivater, deres fremstilling og deresanvendelse i farmasoeytiske preparater.
DK155692D0 (da) Benzofuranylimidazolderivater, fremgangsmaade til deres fremstilling og farmaceutiske praeparater indeholdende disse
DK9086A (da) Naphthalenderivater af benzonorbornen, fremgangsmaade til deres fremstilling og laegemidler og kosmetikpraeparater indeholdende saadanne forbindelser
NO924563L (no) Benzokinoksaliner, fremgangsmaate for deres fremstilling og farmasoeytiske preparater inneholdende de nevnte forbindelser