FI942181A0 - Uudet lupaanijohdannaiset, niiden valmistus ja niitä sisältävät farmaseuttiset valmisteet - Google Patents

Uudet lupaanijohdannaiset, niiden valmistus ja niitä sisältävät farmaseuttiset valmisteet

Info

Publication number
FI942181A0
FI942181A0 FI942181A FI942181A FI942181A0 FI 942181 A0 FI942181 A0 FI 942181A0 FI 942181 A FI942181 A FI 942181A FI 942181 A FI942181 A FI 942181A FI 942181 A0 FI942181 A0 FI 942181A0
Authority
FI
Finland
Prior art keywords
preparation
pharmaceutical preparations
preparations containing
lupane derivatives
new
Prior art date
Application number
FI942181A
Other languages
English (en)
Swedish (sv)
Other versions
FI942181A (fi
Inventor
Romaine Bouboutou
Norbert Dereu
Michel Evers
Jean-Christophe Gueguen
Claude James
Christele Poujade
Daniel Reisdorf
Yves Ribeill
Francoise Soler
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of FI942181A publication Critical patent/FI942181A/fi
Publication of FI942181A0 publication Critical patent/FI942181A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI942181A 1991-11-13 1994-05-11 Uudet lupaanijohdannaiset, niiden valmistus ja niitä sisältävät farmaseuttiset valmisteet FI942181A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9113907A FR2683531B1 (fr) 1991-11-13 1991-11-13 Nouveaux derives du lupane, leur preparation et les compositions pharmaceutiques qui les contiennent.
PCT/FR1992/001046 WO1993010142A1 (fr) 1991-11-13 1992-11-12 Nouveaux derives du lupane, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
FI942181A FI942181A (fi) 1994-05-11
FI942181A0 true FI942181A0 (fi) 1994-05-11

Family

ID=9418832

Family Applications (1)

Application Number Title Priority Date Filing Date
FI942181A FI942181A0 (fi) 1991-11-13 1994-05-11 Uudet lupaanijohdannaiset, niiden valmistus ja niitä sisältävät farmaseuttiset valmisteet

Country Status (11)

Country Link
US (1) US5468888A (fi)
EP (2) EP0613483A1 (fi)
CA (1) CA2121692A1 (fi)
FI (1) FI942181A0 (fi)
FR (1) FR2683531B1 (fi)
HU (1) HUT66959A (fi)
IL (1) IL103731A0 (fi)
MX (1) MX9206503A (fi)
TW (1) TW224103B (fi)
WO (1) WO1993010142A1 (fi)
YU (1) YU97492A (fi)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
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US5962527A (en) * 1995-03-21 1999-10-05 The Board Of Trustees Of The University Of Illinois Method and composition for treating cancers
US5658947A (en) * 1995-03-21 1997-08-19 Board Of Trustees Of The University Of Illinois Method and composition for selectively inhibiting melanoma using betalinic acid
US5869535A (en) 1995-03-21 1999-02-09 The Board Of Trustees Of The University Of Illinois Method and composition for selectively inhibiting melanoma
US5679828A (en) * 1995-06-05 1997-10-21 Biotech Research Labs, Inc. Betulinic acid and dihydrobetulinic acid derivatives and uses therefor
EP0988311B9 (en) * 1997-06-04 2004-12-15 Cornell Research Foundation, Inc. Betulinol derivatives
US6403816B1 (en) * 1997-09-30 2002-06-11 Dabur Research Foundation Betulinic acid derivatives having antiangiogenic activity, processes for producing such derivatives and their use for treating tumor associated angiogenesis
NZ506623A (en) * 1998-03-02 2002-10-25 Univ North Carolina Acylated betulin and dihydrobetulin derivatives, preparation thereof and use in treatment of retroviral infections
US6369101B1 (en) 1999-02-26 2002-04-09 Regents Of The University Of Minnesota Therapeutic method to treat herpes virus infection
US6392070B1 (en) * 1999-08-10 2002-05-21 Regents Of The University Of Minnesota Birch bark processing and the isolation of natural products from birch bark
ES2224735T3 (es) * 1999-09-09 2005-03-01 Dabur Research Foundation Nuevos derivados de acido betulinico que tienen actividad antiangiogenica , procesos para producir dichos derivados y su uso para tratar angiogenesis relacionadas con tumores.
CA2418479C (en) * 2000-08-18 2007-12-18 The Board Of Trustees Of The University Of Illinois Prodrugs of betulinic acid derivatives for the treatment of cancer
WO2002091858A1 (en) * 2001-05-11 2002-11-21 University Of Ottawa Anxiolytic marcgraviaceae compositions containing betulinic acid, betulinic acid derivatives, and methods
GB0128071D0 (en) * 2001-11-22 2002-01-16 Cyclacel Ltd Medicament
US7537765B2 (en) * 2003-01-29 2009-05-26 Panacos Pharmaceuticals, Inc. Inhibition of HIV-1 replication by disruption of the processing of the viral capsid-spacer peptide 1 protein
AU2004210162A1 (en) * 2003-01-29 2004-08-19 Panacos Pharmaceuticals, Inc. Inhibition of HIV-1 replication by disruption of the processing of the viral capsid-spacer peptide 1 protein
US7026305B2 (en) * 2003-04-14 2006-04-11 Meharry Medical College Anti-HIV agents with dual sites of action
US7326717B2 (en) * 2003-05-06 2008-02-05 L'oreal Pyrimidine n-oxide compounds for stimulating the growth of keratin fibers and/or reducing loss thereof
RU2387665C2 (ru) * 2004-03-17 2010-04-27 Панакос Фармасьютикалз, Инк. Фармацевтические соли 3-о-(3', 3'-диметилсукцинил)бетулиновой кислоты
US20060019934A1 (en) * 2004-05-20 2006-01-26 Saxena Brij B Anti-HIV-1 activity of betulinol derivatives
US7282521B2 (en) * 2004-05-24 2007-10-16 University Of North Carolina At Chapel Hill Anti-retroviral moronic acid derivatives
EA200700611A1 (ru) * 2004-09-10 2008-02-28 Бридж Б. Саксена Производные бетулинола в качестве противораковых агентов
TW200628161A (en) * 2004-11-12 2006-08-16 Panacos Pharmaceuticals Inc Novel betulin derivatives, preparation thereof and use thereof
US20060193804A1 (en) * 2005-02-24 2006-08-31 L'oreal Haircare use of cyclic amine derivatives
RU2007141631A (ru) 2005-04-12 2009-05-20 Панакос Фармасьютикалз, Инк. (Us) Полиморфы ди-n-метил-d-глюкамина 3-о-(3',3'-диметилсукцинил)бетулиновой кислоты
JP2008543945A (ja) * 2005-06-22 2008-12-04 ミリアド ジェネティクス， インコーポレイテッド 抗ウイルス化合物
EP1986654A2 (en) * 2006-02-21 2008-11-05 Achillion Pharmaceuticals, Inc. Substituted taraxastanes useful for treating viral infections
US20080039428A1 (en) * 2006-06-29 2008-02-14 Panacos Pharmaceuticals, Inc. Antiretroviral combination therapy
WO2008115281A2 (en) * 2006-10-16 2008-09-25 Myriad Genetics, Inc. Compounds for treating viral infections
RU2317996C1 (ru) * 2006-10-30 2008-02-27 Институт нефтехимии и катализа РАН N'-{n-[3-оксо-лупан-28-оил]-9-аминононаноил}-3-амино-3-фенил-пропионовая кислота и ее соли как противовирусные и иммуностимулирующие агенты
EP2178376A4 (en) * 2007-08-03 2011-12-14 Advanced Life Sciences Inc LUPANIC TRITERPENOIDS MODIFIED IN 30-POSITION AND ITS ANALOG
FR2920309B1 (fr) 2007-08-28 2010-05-28 Galderma Res & Dev Utilisation de travoprost pour traiter la chute des cheveux
WO2009090063A1 (en) * 2008-01-16 2009-07-23 Jado Technologies Gmbh Steroid sapogenin, androstane and triterpenoid sapogenin derivatives for the treatment and prevention of infectious diseases
FR2929118B1 (fr) 2008-03-28 2010-05-07 Oreal Utilisation de l'association de madecassoside et/ou de terminoloside et d'une arginine pour induire et/ou stimuler la croissance de ces fibres keratiniques humaines et/ou freiner leur chute
FR2929117B1 (fr) 2008-03-28 2010-05-07 Oreal Utilisation de l'association du 2,4-diaminopyrimidine 3-n-oxyde et du madecassosside et/ou du terminoloside pour induire et/ou stimuler la croissance de ces fibres keratiniques humaines et/ou freiner leur chute
KR100941595B1 (ko) * 2008-06-05 2010-02-11 주식회사 알앤엘바이오 바이러스 억제제로서 유용한 트리테르페노이드계 화합물
FR2949052B1 (fr) 2009-08-13 2015-03-27 Oreal Procede de traitement cosmetique du cuir chevelu.
CN102558280B (zh) * 2011-11-18 2014-09-17 温州大学 一种30-卤代桦木酸的生产方法
DK2838533T3 (da) 2012-04-16 2017-11-27 Univ Case Western Reserve Sammensætninger og fremgangsmåder til at modulere 15-pgdh-aktivitet
EP2953960A1 (en) * 2013-02-06 2015-12-16 Bristol-Myers Squibb Company C-19 modified triterpenoids with hiv maturation inhibitory activity
US9789116B2 (en) 2013-10-15 2017-10-17 Case Western Reserve University Compositions and methods of modulating short-chain dehydrogenase activity
CN104045680B (zh) 2014-06-20 2016-09-14 东北林业大学 桦木醇的乙酰氨基酸酰类衍生物及其制备方法
PL227790B1 (pl) 2015-08-13 2018-01-31 Slaski Univ Medyczny W Katowicach Fosfoniany acetylenowych pochodnych betuliny o działaniu przeciwnowotworowym, sposób ich wytwarzania i zastosowanie.
US11690847B2 (en) 2016-11-30 2023-07-04 Case Western Reserve University Combinations of 15-PGDH inhibitors with corticosteroids and/or TNF inhibitors and uses thereof
WO2018145080A1 (en) 2017-02-06 2018-08-09 Case Western Reserve University Compositions and methods of modulating short-chain dehydrogenase activity
PL237998B1 (pl) 2018-05-28 2021-06-28 Narodowy Inst Lekow Fosfonowe pochodne kwasu 3-karboksyacylobetulinowego, sposób ich otrzymywania oraz ich zastosowanie
MX2021005982A (es) 2018-11-21 2021-09-23 Univ Case Western Reserve Composiciones y metodos para modular la actividad de deshidrogenasas de cadena corta.
AU2021275122A1 (en) 2020-05-20 2022-12-15 Board Of Regents Of The University Of Texas System Compositions and methods of modulating short-chain dehydrogenase activity

Also Published As

Publication number Publication date
FR2683531A1 (fr) 1993-05-14
YU97492A (sh) 1995-12-04
CA2121692A1 (fr) 1993-05-27
EP0613483A1 (fr) 1994-09-07
US5468888A (en) 1995-11-21
FI942181A (fi) 1994-05-11
IL103731A0 (en) 1993-04-04
FR2683531B1 (fr) 1993-12-31
HU9401353D0 (en) 1994-08-29
HUT66959A (en) 1995-01-30
MX9206503A (es) 1993-05-01
TW224103B (fi) 1994-05-21
EP0542622A1 (fr) 1993-05-19
WO1993010142A1 (fr) 1993-05-27

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