DE68917499T2 - Catechol-Derivate und sie enthaltende pharmazeutische Präparate. - Google Patents
Catechol-Derivate und sie enthaltende pharmazeutische Präparate.Info
- Publication number
- DE68917499T2 DE68917499T2 DE68917499T DE68917499T DE68917499T2 DE 68917499 T2 DE68917499 T2 DE 68917499T2 DE 68917499 T DE68917499 T DE 68917499T DE 68917499 T DE68917499 T DE 68917499T DE 68917499 T2 DE68917499 T2 DE 68917499T2
- Authority
- DE
- Germany
- Prior art keywords
- pharmaceutical preparations
- preparations containing
- catechol derivatives
- catechol
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/22—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/36—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/38—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6351688 | 1988-03-18 | ||
JP6351588A JPH0696520B2 (ja) | 1988-03-18 | 1988-03-18 | カテコールアミン誘導体を含有してなる中枢性神経退行性疾患の進行防止および治療剤 |
JP20186588 | 1988-08-15 | ||
JP63201866A JPH0720929B2 (ja) | 1988-08-15 | 1988-08-15 | ジヒドロカフェイン酸アミド化合物およびそれを有効成分として含有する治療剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68917499D1 DE68917499D1 (de) | 1994-09-22 |
DE68917499T2 true DE68917499T2 (de) | 1995-02-09 |
Family
ID=27464327
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68917499T Expired - Fee Related DE68917499T2 (de) | 1988-03-18 | 1989-03-20 | Catechol-Derivate und sie enthaltende pharmazeutische Präparate. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0333522B1 (de) |
KR (1) | KR910008665B1 (de) |
AU (1) | AU602628B2 (de) |
DE (1) | DE68917499T2 (de) |
DK (1) | DK130389A (de) |
FI (1) | FI891227A (de) |
NO (1) | NO891191L (de) |
NZ (1) | NZ228329A (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DD299424A5 (de) * | 1989-05-23 | 1992-04-16 | Sankyo Company Limited,Jp | Phenolderivate zur foerderung des menschlichen nervenwachstumsfaktors |
JPH0660141B2 (ja) * | 1989-09-12 | 1994-08-10 | 三井東圧化学株式会社 | ジヒドロカフェイン酸誘導体およびそれを有効成分として含有する治療剤 |
US5290793A (en) * | 1989-09-12 | 1994-03-01 | Mitsui Toatsu Chemicals, Incorporated | Dihydrocaffeic acid derivatives and pharmaceutical preparation containing same |
FR2669029B1 (fr) * | 1990-11-14 | 1994-09-02 | Adir | Nouveaux derives de la n-benzoyl proline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
ATE148098T1 (de) * | 1991-02-21 | 1997-02-15 | Sankyo Co | Benzolderivate zum fördern der produktion des nervenwachstumsfaktors |
US5480907A (en) * | 1991-05-16 | 1996-01-02 | Takeda Chemical Industries, Ltd. | Aromatic amide compounds and their production and use |
CA2103367A1 (en) * | 1991-05-20 | 1992-11-21 | Akihide Koda | Phellodendrine analogs and allergy type iv suppressor containing the same as active ingredient |
US6207665B1 (en) | 1997-06-12 | 2001-03-27 | Schering Aktiengesellschaft | Piperazine derivatives and their use as anti-inflammatory agents |
CN1210274C (zh) * | 2000-02-11 | 2005-07-13 | 沃泰克斯药物股份有限公司 | 哌嗪和哌啶衍生物 |
RS51117B (sr) * | 2005-02-28 | 2010-10-31 | Tseti, Ioulia | Lekovi za alchajmerovu bolest |
KR100957465B1 (ko) * | 2006-08-10 | 2010-05-14 | (주)아모레퍼시픽 | 히드록시신남산 유도체 화합물과 그 제조방법 및 이를함유하는 화장료 조성물 |
JP5848698B2 (ja) * | 2009-04-20 | 2016-01-27 | アッヴィ・インコーポレイテッド | 新規アミドおよびアミジン誘導体ならびにこれらの使用 |
EP2243479A3 (de) | 2009-04-20 | 2011-01-19 | Abbott Laboratories | Neuartige Amid- und Amidinderivate und deren Verwendungen |
DE102009031342A1 (de) | 2009-07-01 | 2011-01-05 | Daimler Ag | Verwendung von Schmierölen mit mikrogekapselten Schmierstoffadditiven, Verwendung derselben in Schmierölen für Kraftfahrzeuge mit Verbrennungsmotor und Verbrennungsmotor mit mikrogekapselte Schmierstoffadditive enthaltenden Schmieröl |
FR2964866B1 (fr) * | 2010-09-22 | 2013-03-29 | Oreal | Utilisation comme antipelliculaire de derives ortho-diphenol, nouveaux composes et composition cosmetique les comprenant |
EP2753324B1 (de) * | 2011-09-06 | 2017-12-20 | Novaliq GmbH | Lipophile dopaminderivate und ihre verwendung |
KR101327817B1 (ko) | 2012-03-22 | 2013-11-08 | (주)에이씨티 | 미백 효과를 나타내는 아마이드 유도체의 제조방법 및 상기 아마이드 유도체를 함유하는 화장료 조성물 |
US9540462B2 (en) | 2014-12-05 | 2017-01-10 | Massachusetts Institute Of Technology | Catechol-rich polymers from N-substituted maleimides |
EP3781149A4 (de) * | 2018-04-20 | 2022-03-16 | The General Hospital Corporation | Acetylierte prodrugs zur verabreichung über die blut-hirn-schranke hinweg |
CN114478296A (zh) * | 2022-02-14 | 2022-05-13 | 河南旭瑞新材料科技有限公司 | 一种二氢燕麦生物碱的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4181738A (en) * | 1976-11-30 | 1980-01-01 | Cornell Research Foundation, Inc. | Catecholamine derivatives, a process for their preparation and pharmaceutical compositions thereof |
US4529604A (en) * | 1977-03-28 | 1985-07-16 | Smithkline Beckman Corporation | N,N-Di-(n-Propyl)dopamine derivatives |
US4424205A (en) * | 1982-03-18 | 1984-01-03 | The Procter & Gamble Company | Hydroxyphenylacetamides having analgesic and anti-irritant activity |
PT80304B (en) * | 1984-04-17 | 1987-03-16 | Glaxo Group Ltd | Process for preparing phenethanolamine compounds |
US4579866A (en) * | 1984-05-29 | 1986-04-01 | Usv Pharmaceutical Corp. | Phenylacetamides as anti-allergy, anti-asthma and anti-inflammatory agents |
GB2178031B (en) * | 1985-06-10 | 1989-07-26 | Procter & Gamble | Phenylacetic acid amides having anti-inflammatory and analgesic activity |
FI874163A (fi) * | 1986-09-26 | 1988-03-27 | Mitsui Toatsu Chemicals | Katekolderivat samt preparat innehaollande desamma foer haemmande och botande av regressiva sjukdomar i det centrala nervsystemet. |
-
1989
- 1989-03-14 NZ NZ228329A patent/NZ228329A/en unknown
- 1989-03-15 FI FI891227A patent/FI891227A/fi not_active IP Right Cessation
- 1989-03-17 DK DK130389A patent/DK130389A/da not_active Application Discontinuation
- 1989-03-17 NO NO89891191A patent/NO891191L/no unknown
- 1989-03-17 AU AU31443/89A patent/AU602628B2/en not_active Ceased
- 1989-03-18 KR KR1019890003387A patent/KR910008665B1/ko not_active IP Right Cessation
- 1989-03-20 DE DE68917499T patent/DE68917499T2/de not_active Expired - Fee Related
- 1989-03-20 EP EP89302742A patent/EP0333522B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DK130389D0 (da) | 1989-03-17 |
KR890014098A (ko) | 1989-10-21 |
DK130389A (da) | 1989-09-19 |
FI891227A0 (fi) | 1989-03-15 |
AU3144389A (en) | 1989-09-21 |
EP0333522A3 (de) | 1991-04-17 |
AU602628B2 (en) | 1990-10-18 |
FI891227A (fi) | 1989-09-19 |
NO891191D0 (no) | 1989-03-17 |
NZ228329A (en) | 1991-12-23 |
KR910008665B1 (ko) | 1991-10-19 |
DE68917499D1 (de) | 1994-09-22 |
EP0333522A2 (de) | 1989-09-20 |
NO891191L (no) | 1989-09-19 |
EP0333522B1 (de) | 1994-08-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |