NO930891L - Nye diarylsulfonamider - Google Patents

Nye diarylsulfonamider

Info

Publication number
NO930891L
NO930891L NO93930891A NO930891A NO930891L NO 930891 L NO930891 L NO 930891L NO 93930891 A NO93930891 A NO 93930891A NO 930891 A NO930891 A NO 930891A NO 930891 L NO930891 L NO 930891L
Authority
NO
Norway
Prior art keywords
sulphonamides
halogen
alkyl
compounds
new diaryl
Prior art date
Application number
NO93930891A
Other languages
English (en)
Norwegian (no)
Other versions
NO930891D0 (no
Inventor
Fariborz Mohanedi
Michael Marriott Spees
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO930891D0 publication Critical patent/NO930891D0/no
Publication of NO930891L publication Critical patent/NO930891L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Indole Compounds (AREA)
NO93930891A 1992-03-13 1993-03-11 Nye diarylsulfonamider NO930891L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/850,531 US5169860A (en) 1992-03-13 1992-03-13 Antitumor compositions and methods of treatment

Publications (2)

Publication Number Publication Date
NO930891D0 NO930891D0 (no) 1993-03-11
NO930891L true NO930891L (no) 1993-09-14

Family

ID=25308394

Family Applications (1)

Application Number Title Priority Date Filing Date
NO93930891A NO930891L (no) 1992-03-13 1993-03-11 Nye diarylsulfonamider

Country Status (19)

Country Link
US (1) US5169860A (cs)
EP (1) EP0560554A2 (cs)
JP (1) JPH0649052A (cs)
KR (1) KR930019655A (cs)
CN (1) CN1076447A (cs)
AU (2) AU662605B2 (cs)
BR (1) BR9301137A (cs)
CA (1) CA2091207A1 (cs)
CZ (1) CZ36893A3 (cs)
FI (1) FI931085A7 (cs)
HU (1) HUT63830A (cs)
IL (1) IL104981A0 (cs)
MX (1) MX9301296A (cs)
MY (1) MY111178A (cs)
NO (1) NO930891L (cs)
NZ (1) NZ247083A (cs)
TW (1) TW215083B (cs)
YU (1) YU16893A (cs)
ZA (1) ZA931645B (cs)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254582A (en) * 1992-02-05 1993-10-19 Eli Lilly And Company Antitumor compositions and methods
US5270329A (en) * 1992-12-10 1993-12-14 Eli Lilly And Company Antitumor compositions and methods of treatment
CA2110524A1 (en) * 1992-12-10 1994-06-11 Gerald Burr Grindey Antitumor compositions and methods of treatment
ZA941500B (en) * 1993-03-10 1995-09-04 Lilly Co Eli Antitumor compositions and methods of treatment
US5529999A (en) * 1994-03-04 1996-06-25 Eli Lilly And Company Antitumor compositions and methods of treatment
US5629425A (en) * 1994-09-19 1997-05-13 Eli Lilly And Company Haloalkyl hemisolvates of 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-piperidinoethoxy)-benzoyl]benzo[b]thiophene
CO4410190A1 (es) * 1994-09-19 1997-01-09 Lilly Co Eli 3-[4-(2-AMINOETOXI)-BENZOIL]-2-ARIL-6-HIDROXIBENZO [b] TIOFENO CRISTALINO
US5863936A (en) * 1995-04-18 1999-01-26 Geron Corporation Telomerase inhibitors
AU5258696A (en) * 1996-03-19 1997-10-10 Eli Lilly And Company Synthesis of 3-{4-(2-aminoethoxy)-benzoyl}-2-aryl-6-hydroxy-benzo{b}thiop henes
DE69708340T2 (de) * 1996-08-22 2002-05-16 Dong Wha Pharmaceutical Industrial Co. Ltd., Seoul Arylsulfonylimidazolon-derivate als antitumormittel
CA2267998A1 (en) * 1996-10-04 1998-04-09 Eli Lilly And Company Antitumor compositions and methods of treatment
JP2000247949A (ja) * 1999-02-26 2000-09-12 Eisai Co Ltd スルホンアミド含有インドール化合物
ES2156550B1 (es) * 1999-04-19 2002-02-01 Univ Navarra Publica Derivados de benzo(b) tiofenosulfonamida-1,1-dioxido y su uso como agentes antineoplasicos.
JP4505876B2 (ja) * 1999-05-25 2010-07-21 東ソー株式会社 ４−ハロベンゾフラン誘導体及びその製造方法
TWI281916B (en) * 2001-10-25 2007-06-01 Lilly Co Eli Antitumor compounds and methods
US20050119318A1 (en) * 2003-10-31 2005-06-02 Hudyma Thomas W. Inhibitors of HCV replication
JP5745855B2 (ja) 2007-11-28 2015-07-08 セコイア、ファーマシューティカルズ、インコーポレイテッドＳｅｑｕｏｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． シトクロムｐ４５０ ２ｄ６を阻害するための組成物および方法
KR101300702B1 (ko) * 2011-01-20 2013-08-26 대우조선해양 주식회사 탈가스 장치
CN103450149B (zh) * 2012-06-01 2015-10-14 中国科学院上海有机化学研究所 苯基噻吩磺酰胺类化合物及其制备方法和用途
CN104564805B (zh) * 2013-10-29 2017-11-10 海尔集团公司 一种离心风机的扇叶结构、离心风机及嵌入式空调内机
MA47440B1 (fr) * 2015-02-16 2021-08-31 The Provost Fellows Found Scholars And The Other Members Of Board Of The College Of The Holy & Undiv Sulfonylurées, composés apparentés, et leur utilisation
JP2019518071A (ja) 2016-04-18 2019-06-27 アイエフエム トレ インコーポレイテッド Ｎｌｒｐ活性に関連する状態を処置するための化合物および組成物
JP7235742B2 (ja) 2017-07-07 2023-03-08 インフレイゾーム リミテッド 新規なスルホンアミドカルボキサミド化合物
IL271259B2 (en) 2017-07-24 2024-06-01 Novartis Inflammasome Res Inc Compounds and compositions for treating conditions associated with nlrp activity
WO2019034692A1 (en) 2017-08-15 2019-02-21 Inflazome Limited SULFONYLURATES AND SULFONYLTHIOURES AS INHIBITORS OF NLRP3
RU2020110219A (ru) 2017-08-15 2021-09-17 Инфлазоум Лимитед Сульфонилмочевины и сульфонилтиомочевины в качестве ингибиторов nlrp3
WO2019034693A1 (en) 2017-08-15 2019-02-21 Inflazome Limited SULFONYLURATES AND SULFONYLTHIOURES AS INHIBITORS OF NLRP3
KR20200087759A (ko) 2017-11-09 2020-07-21 인플라좀 리미티드 신규한 설폰아마이드 카복스아마이드 화합물
US12221434B2 (en) 2017-11-09 2025-02-11 Inflazome Limited Sulfonamide carboxamide compounds
WO2019166619A1 (en) 2018-03-02 2019-09-06 Inflazome Limited Novel compounds
JP2022505525A (ja) * 2018-10-24 2022-01-14 ノバルティス アーゲー Ｎｌｒｐ活性に関連する状態を治療するための化合物及び組成物
CN109384764B (zh) * 2018-12-12 2021-09-03 中国科学院上海有机化学研究所 苯基噻吩磺酰胺类化合物、药物组合物、其制备方法和应用
WO2022022646A1 (zh) * 2020-07-29 2022-02-03 南京明德新药研发有限公司 含硒五元杂芳环化合物

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3083207A (en) * 1963-03-26 Indolinesulfonylureas
DE1144259B (de) * 1956-05-29 1963-02-28 Hoechst Ag Verfahren zur Herstellung von Sulfonylharnstoffen
US3097242A (en) * 1960-06-29 1963-07-09 Olin Mathieson Hydrindene sulfonylureas
US3102121A (en) * 1961-06-29 1963-08-27 Olin Mathieson Novel cumaransulfonylureas and 2,3-dihydrothionaphthenesulfonylureas
DE1240866B (de) * 1961-06-29 1967-05-24 Heyden Chem Fab Verfahren zur Herstellung von Indolin-6-sulfonylharnstoffen
NL295122A (cs) * 1962-04-11
US3849110A (en) * 1963-01-07 1974-11-19 Lilly Co Eli Herbicidal method employing aryl-sulfonylureas or salts thereof
US3736122A (en) * 1969-04-10 1973-05-29 C Tung Method of controlling plant growth
IL69621A0 (en) * 1982-09-02 1983-12-30 Duphar Int Res Pharmaceutical compositions having antitumor activity,comprising certain phenylurea derivatives
CA1208561A (en) * 1984-01-19 1986-07-29 Marius S. Brouwer Pharmaceutical compositions containing benzoylurea compounds
US4845128A (en) * 1984-06-27 1989-07-04 Eli Lilly And Company N([(4-trifluoromethylphenyl)amino]carbonyl)benzene sulfonamides
IL80032A (en) * 1985-09-23 1992-07-15 Lilly Co Eli Anti-tumor phenyl-aminocarbonylsulfonamides,their preparation and pharmaceutical compositions containing them
CA1331464C (en) * 1987-05-12 1994-08-16 Eli Lilly And Company Anti-tumor method and compounds
IL98784A0 (en) * 1990-07-17 1992-07-15 Lilly Co Eli Heterocyclyl sulfonamide derivatives,process for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
NO930891D0 (no) 1993-03-11
MY111178A (en) 1999-09-30
ZA931645B (en) 1994-09-08
HU9300688D0 (en) 1993-05-28
AU3519893A (en) 1993-09-16
KR930019655A (ko) 1993-10-18
EP0560554A3 (cs) 1994-01-19
NZ247083A (en) 1995-09-26
HUT63830A (en) 1993-10-28
AU662605B2 (en) 1995-09-07
TW215083B (cs) 1993-10-21
CZ36893A3 (en) 1994-04-13
MX9301296A (es) 1993-10-01
EP0560554A2 (en) 1993-09-15
FI931085L (fi) 1993-09-14
US5169860A (en) 1992-12-08
FI931085A7 (fi) 1993-09-14
CA2091207A1 (en) 1993-09-14
BR9301137A (pt) 1993-09-28
AU4028995A (en) 1996-02-15
FI931085A0 (fi) 1993-03-11
IL104981A0 (en) 1993-07-08
CN1076447A (zh) 1993-09-22
JPH0649052A (ja) 1994-02-22
YU16893A (sh) 1996-07-24

Similar Documents

Publication Publication Date Title
NO930891L (no) Nye diarylsulfonamider
NO159653C (no) Analogifremgangsm te for fremstilling av terapeutisk aktive, sure indol-derivater.
NO986055D0 (no) Nye heterocykliske forbindelser, deres fremstilling, farmas÷ytiske preparat
NO166126C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive kinolonkarboksylsyrederivater.
EP0354777A3 (en) 3-(4-piperidine)-5-(2-sulfonylaminoethyl) indole derivatives
ES2108717T3 (es) Derivados de la tetrahidropirrolo(1,2-a)pirazina-4-espiro-3'-pirrolidina, procedimientos para su preparacion y composiciones farmaceuticas que los contienen.
RU94038255A (ru) Производные бензодиазепина, способ их получения, фармацевтическая композиция
NO163568C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive kinolonkarboksylsyrederivater.
HUT51612A (en) Process for producing quinolinone derivatives and pharmaceutical preparations containing these derivatives as active agents
ATE117677T1 (de) Indolderivate.
NO172340C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktiv 1,5-dideoxy-1,5-imino-(n-omega-methyl-caproat)-l-fucitol
DK154385D0 (da) Tetrahydrothienopyridiner eller farmaceutisk uskadelige salte deraf, deres fremstilling og anvendelse som laegemidler
DE3477664D1 (en) 2-(n-pyrrolidino)-3-isobutoxy-n-phenyl-substituted n-benzylpropyl amines, their preparation and their pharmaceutical use
NO159927C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive aromatiske aminoacetylener.
GR3006108T3 (cs)
NO171639C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive imidazolpyrazolderivater
DE69000806D1 (de) Indol-derivate.
NO159271C (no) Analogifremgangsmaate for fremstiling av terapeutisk aktive substituerte isokinolinderivater.
DK573981A (da) Fremgangsmaade til fremstilling af cis-c-3",c4"-carbonatderivater af o-demethyl-oleandomycin og mellemprodukter herfor
FR2708604A1 (fr) Utilisation de dérivés de benzènesulfonyl-indole pour la préparation de médicaments.
YU47017B (sh) Derivati indola, postupak za njihovo dobijanje i postupak za dobijanje farmaceutskih preparata koji ih sadrže