DE69708340T2 - Arylsulfonylimidazolon-derivate als antitumormittel - Google Patents

Arylsulfonylimidazolon-derivate als antitumormittel

Info

Publication number
DE69708340T2
DE69708340T2 DE69708340T DE69708340T DE69708340T2 DE 69708340 T2 DE69708340 T2 DE 69708340T2 DE 69708340 T DE69708340 T DE 69708340T DE 69708340 T DE69708340 T DE 69708340T DE 69708340 T2 DE69708340 T2 DE 69708340T2
Authority
DE
Germany
Prior art keywords
antituary
agent
arylsulfonylimidazolone
derivatives
arylsulfonylimidazolone derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69708340T
Other languages
English (en)
Other versions
DE69708340D1 (de
Inventor
June Yoon
Ho Chung
Sun Lee
Rack Choi
A Lee
Soon Lee
Ran Yun
Keun Lee
Yi Moon
Sook Hwang
Ha Choi
Hun Jung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dong Wha Pharm Co Ltd
Original Assignee
Dong Wha Pharm Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1019960034920A external-priority patent/KR19980015550A/ko
Priority claimed from KR1019960051939A external-priority patent/KR100438482B1/ko
Priority claimed from KR1019960053450A external-priority patent/KR100435085B1/ko
Priority claimed from KR1019970019365A external-priority patent/KR100437670B1/ko
Application filed by Dong Wha Pharm Ind Co Ltd filed Critical Dong Wha Pharm Ind Co Ltd
Publication of DE69708340D1 publication Critical patent/DE69708340D1/de
Application granted granted Critical
Publication of DE69708340T2 publication Critical patent/DE69708340T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
  • Lubricants (AREA)
  • Developing Agents For Electrophotography (AREA)
DE69708340T 1996-08-22 1997-08-20 Arylsulfonylimidazolon-derivate als antitumormittel Expired - Fee Related DE69708340T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
KR1019960034920A KR19980015550A (ko) 1996-08-22 1996-08-22 신규한 벤조일로 치환된 인돌린설포닐우레아 유도체
KR1019960051939A KR100438482B1 (ko) 1996-11-05 1996-11-05 신규한디아릴설포닐이미다졸론유도체
KR1019960053450A KR100435085B1 (ko) 1996-11-12 1996-11-12 신규설포닐이미다졸론유도체
KR1019970019365A KR100437670B1 (ko) 1997-05-19 1997-05-19 (s)-이성체형태의인돌린설포닐우레아유도체
PCT/KR1997/000154 WO1998007719A1 (en) 1996-08-22 1997-08-20 Arylsulfonylimidazolone derivatives as an antitumor agent

Publications (2)

Publication Number Publication Date
DE69708340D1 DE69708340D1 (de) 2001-12-20
DE69708340T2 true DE69708340T2 (de) 2002-05-16

Family

ID=27483149

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69708340T Expired - Fee Related DE69708340T2 (de) 1996-08-22 1997-08-20 Arylsulfonylimidazolon-derivate als antitumormittel

Country Status (9)

Country Link
US (2) US5929103A (de)
EP (1) EP1021437B1 (de)
JP (1) JP3226100B2 (de)
CN (1) CN1079096C (de)
AT (1) ATE208774T1 (de)
AU (1) AU709107B2 (de)
CA (1) CA2263353C (de)
DE (1) DE69708340T2 (de)
WO (1) WO1998007719A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19919793A1 (de) 1999-04-30 2000-11-02 Bayer Ag Neue Sulfonamide
AU2001256733A1 (en) * 2000-05-16 2001-11-26 Takeda Chemical Industries Ltd. Melanin-concentrating hormone antagonist
KR20030082294A (ko) * 2002-04-17 2003-10-22 주식회사 엘지생명과학 신규한 아릴설포닐우레아 유도체, 그의 제조방법 및 그를함유하는 항암제 조성물
KR20030082292A (ko) * 2002-04-17 2003-10-22 주식회사 엘지생명과학 신규한 인돌린설포닐우레아 유도체 및 그를 함유하는항암제 조성물
US7091232B2 (en) * 2002-05-21 2006-08-15 Allergan, Inc. 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds
US7358269B2 (en) 2002-05-21 2008-04-15 Allergan, Inc. 2-((2-Thioxo-2,3-dihydro-1H-imidazol-4-yl)methyl)-3,4-dihydronapthalen-1(2H)-one
US7323485B2 (en) 2002-05-21 2008-01-29 Allergan, Inc. 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds
GB0421525D0 (en) * 2004-09-28 2004-10-27 Novartis Ag Inhibitors of protein kineses
TWI329102B (en) * 2006-08-15 2010-08-21 Nat Health Research Institutes Thiourea compounds and method for inhibiting hepatitis c virus infection
US7985763B2 (en) * 2007-04-10 2011-07-26 National Health Research Institutes Hepatitis C virus inhibitors
WO2008154091A1 (en) * 2007-06-08 2008-12-18 National Health Research Institutes Thiourea derivatives
KR100965247B1 (ko) * 2008-02-13 2010-06-22 일동제약주식회사 신규한 아릴설포닐이미다졸론 유도체 화합물 및 그화합물을 함유한 항암제 조성물
US8198284B2 (en) * 2008-04-30 2012-06-12 National Health Research Institutes Treatment of neurodegenerative disorders with thiourea compounds
KR101458494B1 (ko) * 2010-07-08 2014-11-07 충남대학교산학협력단 신규한 아릴설포닐이미다졸론 유도체 및 이를 함유하는 항암제 조성물
PL231063B1 (pl) 2013-04-10 2019-01-31 Oncoarendi Therapeutics Spolka Z Ograniczona Odpowiedzialnoscia Pochodne 1-(podstawionej sulfonylo)-2-aminoimidazoliny jako środki przeciwnowotworowe

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110830A (en) * 1984-06-27 1992-05-05 Eli Lilly And Company Benzenesulfonamides treatment of tumors susceptible to
US4845128A (en) * 1984-06-27 1989-07-04 Eli Lilly And Company N([(4-trifluoromethylphenyl)amino]carbonyl)benzene sulfonamides
US5116874A (en) * 1985-09-23 1992-05-26 Eli Lilly And Company Anti-tumor method and compounds
GR862353B (en) * 1985-09-23 1987-01-19 Lilly Co Eli Anti-tumor method and compounds
US4677131A (en) * 1985-11-01 1987-06-30 Merck & Co., Inc. Cyclic ureas as dermal penetration enhancers
JP2764262B2 (ja) * 1987-08-28 1998-06-11 持田製薬株式会社 ヒダントイン誘導体及びそれを有効成分とする医薬組成物
WO1990002126A1 (en) * 1988-08-24 1990-03-08 Mochida Pharmaceutical Co., Ltd. Hydantoin derivatives
IL98784A0 (en) * 1990-07-17 1992-07-15 Lilly Co Eli Heterocyclyl sulfonamide derivatives,process for their preparation and pharmaceutical compositions containing them
US5254582A (en) * 1992-02-05 1993-10-19 Eli Lilly And Company Antitumor compositions and methods
US5169860A (en) * 1992-03-13 1992-12-08 Eli Lilly And Company Antitumor compositions and methods of treatment
CA2110524A1 (en) * 1992-12-10 1994-06-11 Gerald Burr Grindey Antitumor compositions and methods of treatment
US5270329A (en) * 1992-12-10 1993-12-14 Eli Lilly And Company Antitumor compositions and methods of treatment
ZA941500B (en) * 1993-03-10 1995-09-04 Lilly Co Eli Antitumor compositions and methods of treatment

Also Published As

Publication number Publication date
EP1021437A1 (de) 2000-07-26
WO1998007719A1 (en) 1998-02-26
AU709107B2 (en) 1999-08-19
EP1021437B1 (de) 2001-11-14
CN1079096C (zh) 2002-02-13
US5932742A (en) 1999-08-03
CN1228088A (zh) 1999-09-08
CA2263353C (en) 2002-04-23
DE69708340D1 (de) 2001-12-20
JP2000505096A (ja) 2000-04-25
AU3952997A (en) 1998-03-06
CA2263353A1 (en) 1998-02-26
ATE208774T1 (de) 2001-11-15
US5929103A (en) 1999-07-27
JP3226100B2 (ja) 2001-11-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee