YU16893A - Derivati diarilsulfonamida i postupak za njihovo dobijanje - Google Patents
Derivati diarilsulfonamida i postupak za njihovo dobijanjeInfo
- Publication number
- YU16893A YU16893A YU16893A YU16893A YU16893A YU 16893 A YU16893 A YU 16893A YU 16893 A YU16893 A YU 16893A YU 16893 A YU16893 A YU 16893A YU 16893 A YU16893 A YU 16893A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- derivatives
- diarylsulphonamide
- procedure
- production
- halo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Indole Compounds (AREA)
Abstract
DERIVATI DIARILSULFONAMIDA I POSTUPAK ZA NJIHOVO DOBIJANJE, jedinjenje sledeće formule: u kojoj: B je -O-, ili -S-; R1 je halo, C1-C3 alkil, ili vodonik; i R2 je halo, C1-C3 alkil, ili trifluormetil, ili njegova farmaceutski prihvatljiva so ili solvat.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/850,531 US5169860A (en) | 1992-03-13 | 1992-03-13 | Antitumor compositions and methods of treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
YU16893A true YU16893A (sh) | 1996-07-24 |
Family
ID=25308394
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU16893A YU16893A (sh) | 1992-03-13 | 1993-03-11 | Derivati diarilsulfonamida i postupak za njihovo dobijanje |
Country Status (19)
Country | Link |
---|---|
US (1) | US5169860A (sh) |
EP (1) | EP0560554A2 (sh) |
JP (1) | JPH0649052A (sh) |
KR (1) | KR930019655A (sh) |
CN (1) | CN1076447A (sh) |
AU (2) | AU662605B2 (sh) |
BR (1) | BR9301137A (sh) |
CA (1) | CA2091207A1 (sh) |
CZ (1) | CZ36893A3 (sh) |
FI (1) | FI931085A (sh) |
HU (1) | HUT63830A (sh) |
IL (1) | IL104981A0 (sh) |
MX (1) | MX9301296A (sh) |
MY (1) | MY111178A (sh) |
NO (1) | NO930891L (sh) |
NZ (1) | NZ247083A (sh) |
TW (1) | TW215083B (sh) |
YU (1) | YU16893A (sh) |
ZA (1) | ZA931645B (sh) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5254582A (en) * | 1992-02-05 | 1993-10-19 | Eli Lilly And Company | Antitumor compositions and methods |
CA2110524A1 (en) * | 1992-12-10 | 1994-06-11 | Gerald Burr Grindey | Antitumor compositions and methods of treatment |
US5270329A (en) * | 1992-12-10 | 1993-12-14 | Eli Lilly And Company | Antitumor compositions and methods of treatment |
ZA941500B (en) * | 1993-03-10 | 1995-09-04 | Lilly Co Eli | Antitumor compositions and methods of treatment |
US5529999A (en) * | 1994-03-04 | 1996-06-25 | Eli Lilly And Company | Antitumor compositions and methods of treatment |
US5629425A (en) * | 1994-09-19 | 1997-05-13 | Eli Lilly And Company | Haloalkyl hemisolvates of 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-piperidinoethoxy)-benzoyl]benzo[b]thiophene |
CO4410191A1 (es) | 1994-09-19 | 1997-01-09 | Lilly Co Eli | SINTESIS DE 3-[4-(2-AMINOETOXI)BENZOIL]-2-ARIL-6- HIDROXIBENZO [b] TIOFENOS |
US5863936A (en) * | 1995-04-18 | 1999-01-26 | Geron Corporation | Telomerase inhibitors |
CA2249406A1 (en) * | 1996-03-19 | 1997-09-25 | Eli Lilly And Company | Synthesis of 3-¬4-(2-aminoethoxy)-benzoyl|-2-aryl-6-hydroxy-benzo¬b|thiophenes |
ATE208774T1 (de) * | 1996-08-22 | 2001-11-15 | Dong Wha Pharm Ind Co Ltd | Arylsulfonylimidazolon-derivate als antitumormittel |
CA2267998A1 (en) * | 1996-10-04 | 1998-04-09 | Eli Lilly And Company | Antitumor compositions and methods of treatment |
ES2156550B1 (es) * | 1999-04-19 | 2002-02-01 | Univ Navarra Publica | Derivados de benzo(b) tiofenosulfonamida-1,1-dioxido y su uso como agentes antineoplasicos. |
JP4505876B2 (ja) * | 1999-05-25 | 2010-07-21 | 東ソー株式会社 | 4−ハロベンゾフラン誘導体及びその製造方法 |
TWI281916B (en) | 2001-10-25 | 2007-06-01 | Lilly Co Eli | Antitumor compounds and methods |
US20050119318A1 (en) * | 2003-10-31 | 2005-06-02 | Hudyma Thomas W. | Inhibitors of HCV replication |
CA2707161C (en) | 2007-11-28 | 2016-08-16 | Sequoia Pharmaceuticals, Inc. | Compositions and methods for inhibiting cytochrome p450 2d6 |
KR101300702B1 (ko) * | 2011-01-20 | 2013-08-26 | 대우조선해양 주식회사 | 탈가스 장치 |
CN103450149B (zh) * | 2012-06-01 | 2015-10-14 | 中国科学院上海有机化学研究所 | 苯基噻吩磺酰胺类化合物及其制备方法和用途 |
CN104564805B (zh) * | 2013-10-29 | 2017-11-10 | 海尔集团公司 | 一种离心风机的扇叶结构、离心风机及嵌入式空调内机 |
MA47440B1 (fr) * | 2015-02-16 | 2021-08-31 | The Provost Fellows Found Scholars And The Other Members Of Board Of The College Of The Holy & Undiv | Sulfonylurées, composés apparentés, et leur utilisation |
EP3445757B1 (en) * | 2016-04-18 | 2020-11-25 | Novartis Inflammasome Research, Inc. | Compounds and compositions for treating conditions associated with nlrp activity |
EP3978489A1 (en) | 2017-07-07 | 2022-04-06 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
CU24615B1 (es) | 2017-07-24 | 2022-07-08 | Novartis Ag | Compuestos para tratar afecciones asociadas con la actividad nlrp |
US11926600B2 (en) | 2017-08-15 | 2024-03-12 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors |
UY37848A (es) | 2017-08-15 | 2019-03-29 | Inflazome Ltd | Sulfonilureas y sulfoniltioureas útiles como inhibidores de nlrp3 |
CA3071150A1 (en) | 2017-08-15 | 2019-02-21 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as nlrp3 inhibitors |
AU2018363771A1 (en) | 2017-11-09 | 2020-05-14 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
EP3759077A1 (en) | 2018-03-02 | 2021-01-06 | Inflazome Limited | Novel compounds |
CN109384764B (zh) * | 2018-12-12 | 2021-09-03 | 中国科学院上海有机化学研究所 | 苯基噻吩磺酰胺类化合物、药物组合物、其制备方法和应用 |
WO2022022646A1 (zh) * | 2020-07-29 | 2022-02-03 | 南京明德新药研发有限公司 | 含硒五元杂芳环化合物 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3083207A (en) * | 1963-03-26 | Indolinesulfonylureas | ||
DE1144259B (de) * | 1956-05-29 | 1963-02-28 | Hoechst Ag | Verfahren zur Herstellung von Sulfonylharnstoffen |
US3097242A (en) * | 1960-06-29 | 1963-07-09 | Olin Mathieson | Hydrindene sulfonylureas |
US3102121A (en) * | 1961-06-29 | 1963-08-27 | Olin Mathieson | Novel cumaransulfonylureas and 2,3-dihydrothionaphthenesulfonylureas |
DE1240866B (de) * | 1961-06-29 | 1967-05-24 | Heyden Chem Fab | Verfahren zur Herstellung von Indolin-6-sulfonylharnstoffen |
NL295122A (sh) * | 1962-04-11 | |||
US3849110A (en) * | 1963-01-07 | 1974-11-19 | Lilly Co Eli | Herbicidal method employing aryl-sulfonylureas or salts thereof |
US3736122A (en) * | 1969-04-10 | 1973-05-29 | C Tung | Method of controlling plant growth |
IL69621A0 (en) * | 1982-09-02 | 1983-12-30 | Duphar Int Res | Pharmaceutical compositions having antitumor activity,comprising certain phenylurea derivatives |
CA1208561A (en) * | 1984-01-19 | 1986-07-29 | Marius S. Brouwer | Pharmaceutical compositions containing benzoylurea compounds |
US4845128A (en) * | 1984-06-27 | 1989-07-04 | Eli Lilly And Company | N([(4-trifluoromethylphenyl)amino]carbonyl)benzene sulfonamides |
GR862353B (en) * | 1985-09-23 | 1987-01-19 | Lilly Co Eli | Anti-tumor method and compounds |
CA1331464C (en) * | 1987-05-12 | 1994-08-16 | Eli Lilly And Company | Anti-tumor method and compounds |
NZ238911A (en) * | 1990-07-17 | 1993-10-26 | Lilly Co Eli | Furyl, pyrrolyl and thienyl sulphonyl urea derivatives, pharmaceutical compositions and intermediates therefor |
-
1992
- 1992-03-13 US US07/850,531 patent/US5169860A/en not_active Expired - Fee Related
- 1992-04-08 TW TW081102695A patent/TW215083B/zh active
-
1993
- 1993-03-08 ZA ZA931645A patent/ZA931645B/xx unknown
- 1993-03-08 NZ NZ247083A patent/NZ247083A/en unknown
- 1993-03-08 EP EP93301732A patent/EP0560554A2/en not_active Withdrawn
- 1993-03-08 IL IL104981A patent/IL104981A0/xx unknown
- 1993-03-08 CA CA002091207A patent/CA2091207A1/en not_active Abandoned
- 1993-03-08 CZ CZ93368A patent/CZ36893A3/cs unknown
- 1993-03-09 MX MX9301296A patent/MX9301296A/es unknown
- 1993-03-10 HU HU9300688A patent/HUT63830A/hu unknown
- 1993-03-11 AU AU35198/93A patent/AU662605B2/en not_active Ceased
- 1993-03-11 MY MYPI93000440A patent/MY111178A/en unknown
- 1993-03-11 NO NO93930891A patent/NO930891L/no unknown
- 1993-03-11 KR KR1019930003657A patent/KR930019655A/ko not_active Application Discontinuation
- 1993-03-11 BR BR9301137A patent/BR9301137A/pt not_active Application Discontinuation
- 1993-03-11 FI FI931085A patent/FI931085A/fi not_active Application Discontinuation
- 1993-03-11 YU YU16893A patent/YU16893A/sh unknown
- 1993-03-12 JP JP5051911A patent/JPH0649052A/ja active Pending
- 1993-03-12 CN CN93101988A patent/CN1076447A/zh active Pending
-
1995
- 1995-12-07 AU AU40289/95A patent/AU4028995A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
MX9301296A (es) | 1993-10-01 |
BR9301137A (pt) | 1993-09-28 |
MY111178A (en) | 1999-09-30 |
AU4028995A (en) | 1996-02-15 |
TW215083B (sh) | 1993-10-21 |
CZ36893A3 (en) | 1994-04-13 |
NO930891L (no) | 1993-09-14 |
CA2091207A1 (en) | 1993-09-14 |
FI931085A (fi) | 1993-09-14 |
CN1076447A (zh) | 1993-09-22 |
EP0560554A3 (sh) | 1994-01-19 |
KR930019655A (ko) | 1993-10-18 |
US5169860A (en) | 1992-12-08 |
AU662605B2 (en) | 1995-09-07 |
NZ247083A (en) | 1995-09-26 |
ZA931645B (en) | 1994-09-08 |
IL104981A0 (en) | 1993-07-08 |
HU9300688D0 (en) | 1993-05-28 |
JPH0649052A (ja) | 1994-02-22 |
HUT63830A (en) | 1993-10-28 |
AU3519893A (en) | 1993-09-16 |
NO930891D0 (no) | 1993-03-11 |
EP0560554A2 (en) | 1993-09-15 |
FI931085A0 (fi) | 1993-03-11 |
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