NO912860D0 - 3-(1,2,5,6-tetrahydropyridyl)-pyrrolopyridiner. - Google Patents

3-(1,2,5,6-tetrahydropyridyl)-pyrrolopyridiner.

Info

Publication number
NO912860D0
NO912860D0 NO1991912860A NO912860A NO912860D0 NO 912860 D0 NO912860 D0 NO 912860D0 NO 1991912860 A NO1991912860 A NO 1991912860A NO 912860 A NO912860 A NO 912860A NO 912860 D0 NO912860 D0 NO 912860D0
Authority
NO
Norway
Prior art keywords
alkyl
tetrahydropyridyl
alkoxy
formula
pyrrolopyridiner
Prior art date
Application number
NO1991912860A
Other languages
English (en)
Norwegian (no)
Other versions
NO912860L (no
Inventor
John Eugene Macor
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO912860L publication Critical patent/NO912860L/no
Publication of NO912860D0 publication Critical patent/NO912860D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO1991912860A 1989-01-20 1991-07-22 3-(1,2,5,6-tetrahydropyridyl)-pyrrolopyridiner. NO912860D0 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1989/000231 WO1990007926A1 (en) 1989-01-20 1989-01-20 3-(1,2,5,6-tetrahydropyridyl)-pyrrolopyridines

Publications (2)

Publication Number Publication Date
NO912860L NO912860L (no) 1991-07-22
NO912860D0 true NO912860D0 (no) 1991-07-22

Family

ID=22214793

Family Applications (1)

Application Number Title Priority Date Filing Date
NO1991912860A NO912860D0 (no) 1989-01-20 1991-07-22 3-(1,2,5,6-tetrahydropyridyl)-pyrrolopyridiner.

Country Status (26)

Country Link
US (2) US5051412A (cs)
EP (1) EP0379314B1 (cs)
JP (1) JPH0751576B2 (cs)
KR (1) KR920010642B1 (cs)
CN (1) CN1025998C (cs)
AT (1) ATE103282T1 (cs)
CA (1) CA2008016A1 (cs)
CS (1) CS277611B6 (cs)
DD (2) DD291559A5 (cs)
DE (1) DE69007501T2 (cs)
DK (1) DK0379314T3 (cs)
EG (1) EG18945A (cs)
ES (1) ES2062319T3 (cs)
FI (1) FI94641C (cs)
HU (1) HU206349B (cs)
IE (1) IE62757B1 (cs)
IL (1) IL93041A (cs)
MX (1) MX19185A (cs)
MY (1) MY106305A (cs)
NO (1) NO912860D0 (cs)
NZ (1) NZ232166A (cs)
PL (2) PL163626B1 (cs)
PT (1) PT92889A (cs)
WO (1) WO1990007926A1 (cs)
YU (1) YU47553B (cs)
ZA (1) ZA90393B (cs)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX19185A (es) * 1989-01-20 1993-12-01 Pfizer Procedimiento para preparar 3-(1,2,5,6-tretrahidropiridil)-pirrolopiridinas.
US5451566A (en) * 1993-11-17 1995-09-19 Zeneca Limited Herbicidal pyrrolopyridine compounds
US6586458B1 (en) 1996-08-16 2003-07-01 Pozen Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
ZA979961B (en) * 1996-11-15 1999-05-05 Lilly Co Eli 5-HT1F agonists
EP1082958A3 (en) * 1996-11-15 2002-12-11 Eli Lilly And Company 5-HT1F agonists in chronic pain
EP0875513A1 (en) * 1997-04-14 1998-11-04 Eli Lilly And Company Substituted heteroaromatic 5-HT 1F agonists
US5905084A (en) * 1997-11-14 1999-05-18 Eli Lilly And Company 5-HTIF -agonists effective in treating migraine
ZA989389B (en) * 1997-11-14 2000-04-14 Lilly Co Eli Pyrrolo [3,2-b] pyridine processes and intermediates.
US6476034B2 (en) 2000-02-22 2002-11-05 Bristol-Myers Squibb Company Antiviral azaindole derivatives
EP1575566B1 (en) 2002-12-26 2012-02-22 Pozen, Inc. Multilayer dosage forms containing naproxen and triptans
CN102786482A (zh) * 2003-11-21 2012-11-21 阿雷生物药品公司 Akt蛋白激酶抑制剂
US7361764B2 (en) 2004-07-27 2008-04-22 Sgx Pharmaceuticals, Inc. Pyrrolo-pyridine kinase modulators
US7626021B2 (en) * 2004-07-27 2009-12-01 Sgx Pharmaceuticals, Inc. Fused ring heterocycle kinase modulators
EP2264033A1 (en) 2004-07-27 2010-12-22 SGX Pharmaceuticals, Inc. 3,5-DIPHENYL-SUBSTITUTED PYRROLO[2,3b]PYRIDINES USEFUL AS KINASE INHIBITORS
BRPI0513899A (pt) 2004-07-27 2008-05-20 Sgx Pharmaceuticals Inc moduladores de cinase heterocìclica de anel fundido
US20060100432A1 (en) 2004-11-09 2006-05-11 Matiskella John D Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione
US7851476B2 (en) 2005-12-14 2010-12-14 Bristol-Myers Squibb Company Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-YL)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-C]pyridin-3-YL]-1,2-dioxoethyl]-piperazine
US7807671B2 (en) 2006-04-25 2010-10-05 Bristol-Myers Squibb Company Diketo-piperazine and piperidine derivatives as antiviral agents
US8063050B2 (en) 2006-07-06 2011-11-22 Array Biopharma Inc. Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors
DE602007011628D1 (de) 2006-07-06 2011-02-10 Array Biopharma Inc Dihydrofuropyrimidine als akt-proteinkinaseinhibitoren
JP5268904B2 (ja) 2006-07-06 2013-08-21 アレイ バイオファーマ、インコーポレイテッド Ａｋｔプロテインキナーゼ阻害剤としてのシクロペンタ［ｄ］ピリミジン
CN101516891B (zh) 2006-07-06 2013-06-05 阵列生物制药公司 作为akt蛋白激酶抑制剂的二氢噻吩并嘧啶
EP2114955B1 (en) * 2006-12-29 2013-02-13 Rigel Pharmaceuticals, Inc. Bridged bicyclic aryl and bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors
NZ582692A (en) 2007-07-05 2012-05-25 Array Biopharma Inc Pyrimidyl cyclopentanes as akt protein kinase inhibitors
US9409886B2 (en) 2007-07-05 2016-08-09 Array Biopharma Inc. Pyrimidyl cyclopentanes as AKT protein kinase inhibitors
KR20150091196A (ko) * 2007-07-05 2015-08-07 어레이 바이오파마 인크. Ａｋｔ 단백질 키나제 억제제로서의 피리미딜 시클로펜탄
US8846683B2 (en) 2007-07-05 2014-09-30 Array Biopharma, Inc. Pyrimidyl cyclopentanes as Akt protein kinase inhibitors
CN101932565B (zh) * 2008-01-09 2013-06-12 阵列生物制药公司 作为akt蛋白激酶抑制剂的羟基化嘧啶基环戊烷
BRPI0906798A2 (pt) * 2008-01-09 2015-07-14 Array Biopharma Inc Pirimidil ciclopentanos hidroxilados como inibidores de proteína quinase akt
CA2749843C (en) 2009-01-16 2017-09-05 Rigel Pharmaceuticals, Inc. Axl inhibitors for use in combination therapy for preventing, treating or managing metastatic cancer
EP2442809B1 (en) 2009-06-17 2016-08-31 Vertex Pharmaceuticals Incorporated Inhibitors of influenza viruses replication
EP2651940A1 (en) 2010-12-16 2013-10-23 Vertex Pharmaceuticals Incorporated Inhibitors of influenza viruses replication
PL2694073T3 (pl) 2011-04-01 2019-06-28 Genentech, Inc. Kombinacje inhibitorów AKT i MEK do leczenia nowotworu
RU2631240C2 (ru) 2011-04-01 2017-09-20 Дженентек, Инк. Комбинации соединений-ингибиторов акт и абиратерона, и способы применения
UA118010C2 (uk) 2011-08-01 2018-11-12 Вертекс Фармасьютікалз Інкорпорейтед Інгібітори реплікації вірусів грипу
EP3610890A1 (en) 2012-11-14 2020-02-19 The Johns Hopkins University Methods and compositions for treating schizophrenia
HUE052178T2 (hu) 2013-11-13 2021-04-28 Vertex Pharma Eljárások influenzavírus-replikáció inhibitorainak elõállítására
HRP20191525T1 (hr) 2013-11-13 2019-11-29 Vertex Pharma Inhibitori replikacije virusa influence
MX371152B (es) * 2014-10-23 2020-01-20 Janssen Pharmaceutica Nv Nuevos derivados de pirazolopirimidina como inhibidores de la cinasa inductora de nf-kb (nk).
KR102524622B1 (ko) 2014-10-23 2023-04-20 얀센 파마슈티카 엔.브이. Ｎｉｋ 억제제로서의 신규 티에노피리미딘 유도체
MA42422A (fr) 2015-05-13 2018-05-23 Vertex Pharma Inhibiteurs de la réplication des virus de la grippe
WO2016183116A1 (en) 2015-05-13 2016-11-17 Vertex Pharmaceuticals Incorporated Methods of preparing inhibitors of influenza viruses replication

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3272804A (en) * 1963-12-23 1966-09-13 Sterling Drug Inc Process and intermediates for preparing indoles
GB1141949A (en) * 1966-02-23 1969-02-05 Sterling Drug Inc 7-azaindole derivatives
IL48508A (en) * 1974-12-09 1979-10-31 Roussel Uclaf Pharmaceutical compositions comprising piperidylindole derivatives
FR2362628A1 (fr) * 1976-08-26 1978-03-24 Roussel Uclaf Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments
FR2421899A1 (fr) * 1978-01-16 1979-11-02 Roussel Uclaf Nouveaux derives du tetrahydropyridinyl-indole et leurs sels, le procede de preparation et l'application a titre de medicaments de ces nouveaux produits
FR2444678A2 (fr) * 1978-12-22 1980-07-18 Roussel Uclaf Nouveau procede de preparation de derives du piperidyl-indole et de leurs sels
US5025096A (en) * 1985-08-22 1991-06-18 Mine Safety Appliances Company Preparation of indole and indole derivatives
MX19185A (es) * 1989-01-20 1993-12-01 Pfizer Procedimiento para preparar 3-(1,2,5,6-tretrahidropiridil)-pirrolopiridinas.

Also Published As

Publication number Publication date
MX19185A (es) 1993-12-01
IE62757B1 (en) 1995-02-22
IE900210L (en) 1990-07-23
MY106305A (en) 1995-04-29
HUT57762A (en) 1991-12-30
PT92889A (pt) 1990-07-31
ATE103282T1 (de) 1994-04-15
YU47553B (sh) 1995-10-03
IL93041A0 (en) 1990-11-05
KR900011772A (ko) 1990-08-02
FI94641B (fi) 1995-06-30
DK0379314T3 (da) 1994-05-09
CN1044465A (zh) 1990-08-08
CA2008016A1 (en) 1990-07-20
AU613259B2 (en) 1991-07-25
US5051412A (en) 1991-09-24
NZ232166A (en) 1992-10-28
KR920010642B1 (ko) 1992-12-12
IL93041A (en) 1994-02-27
AU4867390A (en) 1990-07-26
US5169947A (en) 1992-12-08
DE69007501D1 (de) 1994-04-28
JPH02247175A (ja) 1990-10-02
WO1990007926A1 (en) 1990-07-26
CN1025998C (zh) 1994-09-28
DD291559A5 (de) 1991-07-04
ES2062319T3 (es) 1994-12-16
CS26090A3 (en) 1992-02-19
CS277611B6 (en) 1993-03-17
EP0379314A1 (en) 1990-07-25
NO912860L (no) 1991-07-22
EG18945A (en) 1994-09-29
EP0379314B1 (en) 1994-03-23
FI94641C (fi) 1995-10-10
PL163626B1 (pl) 1994-04-29
ZA90393B (en) 1991-08-28
PL287840A1 (en) 1991-07-15
HU206349B (en) 1992-10-28
JPH0751576B2 (ja) 1995-06-05
DD298398A5 (de) 1992-02-20
DE69007501T2 (de) 1994-06-30
YU9990A (en) 1992-05-28
PL283354A1 (en) 1991-08-12
FI913509A0 (fi) 1991-07-22

Similar Documents

Publication Publication Date Title
ATE103282T1 (de) 3-(1,2,5,6-tetrahydropyridyl)-pyrrolopyridine.
CS845583A2 (en) Zpusob pripravy 4 ep homoerythromycinu a
AU2215588A (en) Substituted cycloalkanols
ES2057899T3 (es) Procedimiento para la preparacion estereoselectiva de derivados de la fenilisoserina.
NZ228632A (en) Topical otopathic preparations containing ofloxacin
GR3024925T3 (en) Antifungal agent, its preparation and microorganism therefor
GR3036754T3 (en) Use of isoxazole- and crotonamide derivatives for the manufacture of a medicament for the treatment of cancers
ATE61353T1 (de) 2,3-diaminoacrylonitrilderivate.
FR2263752A1 (en) 1,8-Naphthyridine derivs - tranquillizers and anti-convulsants
HU0002288D0 (en) New compounds of 7-oxo-2,3,7,14-tetrahydro-1h-benzo[b]pyrano[3,2-4]acridin carboxylate, a process for their preparation and pharmaceutical compositions containing them
DK0468504T3 (da) Et nye antibiotikum, balhimycin, en fremgangsmåde til dets fremstilling samt dets anvendelse som lægemiddel
PT81324A (en) Process for the preparation of s-aralkyltrithiophosphonate having an insecticidal effect
IT1240836B (it) Impiego di attivatori dei canali potassici per la profilassi dell'asma
EP0171812A3 (en) Cephem derivatives
CH503682A (de) Verfahren zur Herstellung von carbocyclischen Verbindungen
CS153685A1 (en) Treatment method of staple yarn spinned by rotor system
ES8609254A1 (es) Un procedimiento para preparar un derivado de piridinodicar-boxilato
IT8584116A0 (it) Dispositivo per regolare la planarita' di un'anta, particolarmente di armadio.
ITMI910339U1 (it) Distributore d'aria a lamelle multiple per l'alimentazione al minimo d i un motore a c. i .