NO892303L - Stabilisert fgf-sammensetning og fremstilling derav. - Google Patents
Stabilisert fgf-sammensetning og fremstilling derav.Info
- Publication number
- NO892303L NO892303L NO89892303A NO892303A NO892303L NO 892303 L NO892303 L NO 892303L NO 89892303 A NO89892303 A NO 89892303A NO 892303 A NO892303 A NO 892303A NO 892303 L NO892303 L NO 892303L
- Authority
- NO
- Norway
- Prior art keywords
- mutein
- fgf
- sulfate
- glucan
- amino acid
- Prior art date
Links
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
- C07K14/503—Fibroblast growth factor [FGF] basic FGF [bFGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Inorganic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13890788 | 1988-06-06 | ||
| JP18577288 | 1988-07-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO892303D0 NO892303D0 (no) | 1989-06-05 |
| NO892303L true NO892303L (no) | 1989-12-07 |
Family
ID=26471846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO89892303A NO892303L (no) | 1988-06-06 | 1989-06-05 | Stabilisert fgf-sammensetning og fremstilling derav. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5314872A (zh) |
| EP (1) | EP0345660B1 (zh) |
| JP (1) | JP2929200B2 (zh) |
| KR (1) | KR910001044A (zh) |
| CN (1) | CN1038765A (zh) |
| AT (1) | ATE79762T1 (zh) |
| AU (1) | AU614137B2 (zh) |
| CA (1) | CA1329763C (zh) |
| DE (1) | DE68902583T2 (zh) |
| DK (1) | DK246589A (zh) |
| FI (1) | FI892727A (zh) |
| HU (1) | HU205144B (zh) |
| IL (1) | IL90348A0 (zh) |
| NO (1) | NO892303L (zh) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5175147A (en) * | 1988-08-19 | 1992-12-29 | Takeda Chemical Industries, Ltd | Acid-resistant fgf composition and method of treating ulcerating diseases of the gastrointestinal tract |
| US5202311A (en) * | 1988-08-19 | 1993-04-13 | Children's Medical Center Corporation | Stabilized fgf composition |
| US5217954A (en) * | 1990-04-04 | 1993-06-08 | Scios Nova Inc. | Formulations for stabilizing fibroblast growth factor |
| GB9015824D0 (en) * | 1990-07-18 | 1990-09-05 | Erba Carlo Spa | Stable pharmaceutical compositions containing a fibroblast growth factor |
| US5714458A (en) * | 1990-07-18 | 1998-02-03 | Farmitalia Carlo Erba S.R.L. | Stable pharmaceutical compositions containing a fibroblast growth factor |
| AU1052492A (en) * | 1991-01-31 | 1992-08-06 | Farmitalia Carlo Erba S.R.L. | Synergistic composition comprising a fibroblast growth factor and a sulfated polylsaccharide, for use as antiviral agent |
| GB9102107D0 (en) * | 1991-01-31 | 1991-03-13 | Erba Carlo Spa | Stabilisation of fibroblast growth factor using a polysaccharide |
| JPH0771459B2 (ja) * | 1991-05-15 | 1995-08-02 | 三協食品工業株式会社 | 機能性食品素材とその製造方法 |
| US5605938A (en) * | 1991-05-31 | 1997-02-25 | Gliatech, Inc. | Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate |
| US5705178A (en) * | 1991-05-31 | 1998-01-06 | Gliatech, Inc. | Methods and compositions based on inhibition of cell invasion and fibrosis by anionic polymers |
| DE4121043A1 (de) * | 1991-06-26 | 1993-01-07 | Merck Patent Gmbh | Knochenersatzmaterial mit fgf |
| CA2080537A1 (en) * | 1991-10-21 | 1993-04-22 | David B. Volkin | Stabilized topical acidic fibroblast growth factor formulation |
| CA2080538A1 (en) * | 1991-10-21 | 1993-04-22 | Joseph V. Bondi | Lyophilized acidic fibroblast growth factor |
| BR9206736A (pt) * | 1991-11-11 | 1995-10-31 | Univ Pennsylvania | Composição para afetar o crescimento de tecido vivo em mamíferos processos para promover a angiogenese em mamíferos para tratar tecido transplantado ou órgãos em mamíferos e para tratar osso danificado ou transplantado |
| US5482929A (en) * | 1991-12-26 | 1996-01-09 | Kaken Pharmaceutical Co., Ltd. | Composition of stabilized fibroblast growth factor |
| EP0580874A4 (en) * | 1992-02-14 | 1997-02-26 | Kaken Pharma Co Ltd | Remedy for airway diseases |
| DE4242889A1 (de) * | 1992-12-18 | 1994-06-23 | Merck Patent Gmbh | Hohlendoprothesen mit Knochenwachstumsfördernder Füllung |
| US5464815A (en) * | 1993-09-08 | 1995-11-07 | Genentech, Inc. | Inhibition of heparin-binding |
| JPH11130636A (ja) * | 1997-10-28 | 1999-05-18 | Noevir Co Ltd | 毛髪用化粧料 |
| CN1379681A (zh) * | 1998-04-17 | 2002-11-13 | 安乔格尼克斯公司 | 治疗性的血管生成因子及其使用方法 |
| US6440934B1 (en) * | 1998-10-13 | 2002-08-27 | Chiron Corporation | Angiogenically effective unit dose of FGF-2 and method of use |
| US8618052B2 (en) | 1998-10-13 | 2013-12-31 | Novartis Vaccines And Diagnostics, Inc. | Method of treating coronary artery disease by administering FGF-5 |
| EP1121141A2 (en) | 1998-10-13 | 2001-08-08 | Chiron Corporation | Angiogenically effective unit dose of fgf and method of administering |
| US20030166550A1 (en) | 1999-08-27 | 2003-09-04 | Chiron Corporation | Angiogenically effective unit dose of FGF-2 and method of use |
| US20020072489A1 (en) * | 1998-10-13 | 2002-06-13 | Whitehouse Martha J. | Angiogenically effective unit dose of FGF-2 and method of use |
| WO2001013031A2 (en) * | 1999-08-13 | 2001-02-22 | Chiron Corporation | Dose of an angiogenic factor and method of administering to improve myocardial blood flow |
| US7754686B2 (en) * | 2000-08-31 | 2010-07-13 | Novartis Vaccines And Diagnostics, Inc. | Stabilized FGF formulations containing reducing agents |
| JP5296531B2 (ja) | 2005-05-05 | 2013-09-25 | センシエント フレイバーズ エルエルシー | βグルカン及びマンナンの製造 |
| US20080032343A1 (en) | 2005-12-22 | 2008-02-07 | Genentech, Inc. | Recombinant Production of Heparin Binding Proteins |
| WO2009132457A1 (en) * | 2008-05-02 | 2009-11-05 | University Of Western Ontario | Fgf-9 and its use relating to blood vessels |
| FR2948286B1 (fr) | 2009-07-27 | 2011-08-26 | Jean-Noel Thorel | Composition injectable associant un agent de comblement et un milieu de croissance des fibroblastes |
| FR2954165B1 (fr) * | 2009-12-18 | 2012-01-13 | Jean-Noel Thorel | Compositions injectables a usage intra-articulaire associant un agent de viscosupplementation et un milieu de croissance des fibroblastes |
| EP2832848B1 (en) * | 2012-03-30 | 2019-02-13 | Ajinomoto Co., Inc. | Culture medium for proliferating stem cell, which contains sulfated compound |
| CN105288591A (zh) * | 2015-10-29 | 2016-02-03 | 段懿玲 | 碱性成纤维细胞生长因子组合物及其在制备治疗脊髓损伤的药物中的应用 |
| LT3380508T (lt) | 2015-11-27 | 2020-11-10 | Masarykova Univerzita | Termostabilus fgf2 polipeptidas, jo panaudojimas |
| WO2017104567A1 (ja) * | 2015-12-15 | 2017-06-22 | 協和メデックス株式会社 | 線維芽細胞増殖因子－２３の安定化剤 |
| EP3612637A4 (en) * | 2017-04-21 | 2021-01-27 | Yuhan Corporation | DOUBLE-FUNCTION PROTEIN PRODUCTION PROCESS AND ITS DERIVATIVES |
| US20200080995A1 (en) * | 2017-05-31 | 2020-03-12 | Hitachi Chemical Diagnostics Systems Co., Ltd. | Measurement Method for Fibroblast Growth Factor-23, Measurement Reagent, and Measurement Kit |
| JP7177696B2 (ja) * | 2018-12-28 | 2022-11-24 | 日清ファルマ株式会社 | 生理活性ペプチド又は生理活性タンパク質の活性低下抑制剤 |
| CN110151977B (zh) * | 2019-05-29 | 2022-11-29 | 新乡医学院 | 一种保护aFGF蛋白药物稳定性和活性的方法 |
| TW202233225A (zh) * | 2020-11-16 | 2022-09-01 | 雅祥生技醫藥股份有限公司 | 穩定的酸性纖維母細胞生長因子組合物 |
| EP4183796A1 (en) | 2021-11-19 | 2023-05-24 | Enantis s.r.o. | Thermostable fgf10 polypeptide or fragment thereof use thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4296100A (en) * | 1980-06-30 | 1981-10-20 | Franco Wayne P | Method of treating the heart for myocardial infarction |
| NZ222413A (en) * | 1986-11-05 | 1991-06-25 | Ethicon Inc | Compositions containing a polypeptide growth factor and a water-soluble cellulose polymer stabiliser |
| US4717717A (en) * | 1986-11-05 | 1988-01-05 | Ethicon, Inc. | Stabilized compositions containing epidermal growth factor |
| US5013714A (en) * | 1988-12-15 | 1991-05-07 | Lindstrom Richard L | Viscoelastic solution |
-
1989
- 1989-05-18 AU AU34969/89A patent/AU614137B2/en not_active Ceased
- 1989-05-19 IL IL90348A patent/IL90348A0/xx unknown
- 1989-05-22 DK DK246589A patent/DK246589A/da not_active Application Discontinuation
- 1989-06-02 DE DE8989110016T patent/DE68902583T2/de not_active Expired - Fee Related
- 1989-06-02 FI FI892727A patent/FI892727A/fi not_active IP Right Cessation
- 1989-06-02 AT AT89110016T patent/ATE79762T1/de not_active IP Right Cessation
- 1989-06-02 US US07/360,602 patent/US5314872A/en not_active Expired - Fee Related
- 1989-06-02 EP EP89110016A patent/EP0345660B1/en not_active Expired - Lifetime
- 1989-06-02 JP JP1141998A patent/JP2929200B2/ja not_active Expired - Fee Related
- 1989-06-05 CA CA000601806A patent/CA1329763C/en not_active Expired - Fee Related
- 1989-06-05 KR KR1019890007758A patent/KR910001044A/ko not_active Application Discontinuation
- 1989-06-05 NO NO89892303A patent/NO892303L/no unknown
- 1989-06-05 CN CN89103971A patent/CN1038765A/zh active Pending
- 1989-06-06 HU HU892895A patent/HU205144B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO892303D0 (no) | 1989-06-05 |
| CN1038765A (zh) | 1990-01-17 |
| DE68902583D1 (de) | 1992-10-01 |
| EP0345660A1 (en) | 1989-12-13 |
| HUT52393A (en) | 1990-07-28 |
| DK246589A (da) | 1989-12-07 |
| FI892727A (fi) | 1989-12-07 |
| EP0345660B1 (en) | 1992-08-26 |
| FI892727A0 (fi) | 1989-06-02 |
| JPH02138223A (ja) | 1990-05-28 |
| CA1329763C (en) | 1994-05-24 |
| JP2929200B2 (ja) | 1999-08-03 |
| IL90348A0 (en) | 1989-12-15 |
| KR910001044A (ko) | 1991-01-30 |
| AU614137B2 (en) | 1991-08-22 |
| AU3496989A (en) | 1989-12-07 |
| HU205144B (en) | 1992-03-30 |
| DK246589D0 (da) | 1989-05-22 |
| US5314872A (en) | 1994-05-24 |
| ATE79762T1 (de) | 1992-09-15 |
| DE68902583T2 (de) | 1993-01-21 |
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