NO811119L - Forbedrede baerere, samt fremgangsmaate ved fremstilling av disse og for aa uttrykke klonede gener - Google Patents

Forbedrede baerere, samt fremgangsmaate ved fremstilling av disse og for aa uttrykke klonede gener

Info

Publication number
NO811119L
NO811119L NO811119A NO811119A NO811119L NO 811119 L NO811119 L NO 811119L NO 811119 A NO811119 A NO 811119A NO 811119 A NO811119 A NO 811119A NO 811119 L NO811119 L NO 811119L
Authority
NO
Norway
Prior art keywords
promoter
fragment
gene
dna
bamhi
Prior art date
Application number
NO811119A
Other languages
English (en)
Norwegian (no)
Inventor
Walter Charles Fiers
Erik Rene Remaut
Original Assignee
Biogen Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27260930&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO811119(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Nv filed Critical Biogen Nv
Publication of NO811119L publication Critical patent/NO811119L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/565IFN-beta
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • C12N15/73Expression systems using phage (lambda) regulatory sequences
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/22011Polyomaviridae, e.g. polyoma, SV40, JC
    • C12N2710/22022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
NO811119A 1980-06-06 1981-04-01 Forbedrede baerere, samt fremgangsmaate ved fremstilling av disse og for aa uttrykke klonede gener NO811119L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB8018701 1980-06-06
GB8026661 1980-08-15
GB8028983 1980-09-08

Publications (1)

Publication Number Publication Date
NO811119L true NO811119L (no) 1981-12-07

Family

ID=27260930

Family Applications (1)

Application Number Title Priority Date Filing Date
NO811119A NO811119L (no) 1980-06-06 1981-04-01 Forbedrede baerere, samt fremgangsmaate ved fremstilling av disse og for aa uttrykke klonede gener

Country Status (17)

Country Link
EP (1) EP0041767B1 (fr)
JP (6) JPH0787785B2 (fr)
KR (1) KR860001557B1 (fr)
BG (1) BG60443B2 (fr)
BR (1) BR8101972A (fr)
CA (1) CA1207251A (fr)
DD (1) DD158918A5 (fr)
DE (1) DE3177298T2 (fr)
DK (1) DK171301B1 (fr)
ES (1) ES8302774A1 (fr)
FI (1) FI811009L (fr)
GR (1) GR74282B (fr)
IE (1) IE63126B1 (fr)
IL (1) IL62553A (fr)
NO (1) NO811119L (fr)
PH (1) PH22618A (fr)
YU (1) YU87581A (fr)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5554513A (en) * 1979-11-21 1996-09-10 Yeda Research & Development Co. Ltd. Production of recombinant human interferon-beta2
IL58765A (en) * 1979-11-21 1986-09-30 Yeda Res & Dev Process for the production of essentially pure messenger rna of human fibroblast interferon and process for the production of interferon beta
US5510472A (en) * 1979-11-21 1996-04-23 Yeda Research And Development Co. Ltd. Production of recombinant human interferon-beta2
YU45104B (en) 1980-04-03 1992-03-10 Biogen Nv Process for producing recombinant dnk molecule, capable of inducting polypeptide expression in an one-cell host
IL65475A0 (en) * 1981-04-17 1982-07-30 Meloy Lab Production of immune interferon and its mrna
EP0068693A3 (fr) * 1981-06-16 1983-07-20 Genentech, Inc. Production d'un vaccin contre la fièvre aphteuse à partir d'antigènes entraits micro-biologiquement
JPS5835198A (ja) * 1981-08-28 1983-03-01 Mitsubishi Petrochem Co Ltd 新規ベクター
ZA831854B (en) * 1982-03-26 1984-01-25 Biogen Nv Small peptides with the specificity of foot and mouth disease viral antigens
EP0090433A1 (fr) * 1982-03-31 1983-10-05 Genetics Institute, Inc. Création des séquences d'ADN codant des précurseurs de proinsuline modifiée
FR2526661B1 (fr) * 1982-05-13 1986-02-21 Transgene Sa Nouveaux vecteurs d'expression de la proteine antigenique de la rage et leur application a la preparation de vaccins
US4582800A (en) * 1982-07-12 1986-04-15 Hoffmann-La Roche Inc. Novel vectors and method for controlling interferon expression
CA1209501A (fr) * 1982-09-16 1986-08-12 Nikos Panayotatos Vecteur d'expression
CA1341012C (fr) * 1982-09-27 2000-06-06 Biogen, Inc. Sequences d'adn, molecules d'adn recombinant, ainsi que des procedes de synthese de polypeptides aux proprietes analogues a l'hormone de croissance porcine
EP0121569B1 (fr) * 1982-10-08 1990-08-22 Kyowa Hakko Kogyo Co., Ltd. Nouveau vecteur
FR2539758B1 (fr) * 1983-01-21 1985-11-15 Transgene Sa Nouveaux vecteurs d'expression et leur application a la preparation d'une proteine ayant l'activite de l'antitrypsine-a1 humaine
CA1303530C (fr) * 1983-01-21 1992-06-16 Michael Courtney VECTEURS D'EXPRESSION ET LEUR UTILISATION POUR LA PREPARATION D'UNE PROTEINE AYANT UNE ACTIVITE .alpha. -ANTITRYPSINE HUMAINE
GB8308235D0 (en) * 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
DE3319242A1 (de) * 1983-05-27 1984-11-29 Battelle-Institut E.V., 6000 Frankfurt Verfahren und plasmid zur steuerung der expression von klonierten genen
US5670371A (en) * 1983-07-15 1997-09-23 Bio-Technology General Corp. Bacterial expression of superoxide dismutase
BG49718A3 (en) * 1983-07-15 1992-01-15 Bio Technology General Corp Method for preparing of polypeptid with superoxiddismutasne activitty
US5162216A (en) * 1983-09-23 1992-11-10 Enzon Labs Inc. Hybrid gene regulatory region operable in E. coli
FR2556365B1 (fr) * 1983-12-09 1987-07-31 Transgene Sa Vecteurs de clonage et d'expression de l'interferon-g, bacteries transformees et procede de preparation de l'interferon-g
US4711845A (en) * 1984-08-31 1987-12-08 Cetus Corporation Portable temperature-sensitive control cassette
DE3587730T2 (de) * 1984-02-08 1994-05-05 Cetus Oncology Corp Kontrollsysteme für rekombinant-manipulationen.
US5081020A (en) * 1984-08-27 1992-01-14 Bio-Technology General Corp. Expression vectors containing λPL promoter, T1 T2 rRNA termination sequence and origin of replication derived from a constitutive high copy number plasmid hosts and related methods
US5143836A (en) * 1984-08-27 1992-09-01 Bio-Technology General Corp. Plasmids for expression of human superoxide dismutase (SOD) analogs containing lambda pl promoter with engineered restriction site for substituting ribosomal binding sites and methods of use thereof
US5162217A (en) * 1984-08-27 1992-11-10 Bio-Technology General Corp. Plasmids for expression of human superoxide dismutase (SOD) analogs containing lambda PL promoter with engineered restriction site for substituting ribosomal binding sites and methods of use thereof
CA1340597C (fr) * 1984-08-27 1999-06-22 Haim Aviv Vecteurs d'expression renfermant le promoteur pl et site de restriction synthetique facilitant le remplacement du site de liaison aux ribosomes; plasmides contenant les vecteurs, hotes contenant les plasmides et methodes connexes
US5112744A (en) * 1984-08-27 1992-05-12 Bio-Technology General Corp. Plasmids for the production of human Cu-Zn superoxide dismutase, bacterial hosts containing the plasmids and methods for production and recovery of such superoxide dismutase
US5059529A (en) * 1984-08-27 1991-10-22 Bio-Technology General Corp. Stabilized expression vectors containing λPL promoter and the gene for the cI434 repressor, plasmids containing the vectors, hosts containing the plasmids and related methods
US5126252A (en) * 1984-08-27 1992-06-30 Bio-Technology General Corp. Expressions vectors containing Lambda PL promoter and T1 T2 RNA termination sequence, plasmids containing the vectors, hosts containing the plasmids and relatedmethods
US5759816A (en) * 1984-08-27 1998-06-02 Bio-Technology General Corp. Expression vectors containing λPL promoter and T1 T2 rRNA termination sequence plasmids containing the vectors hosts containing the plasmids and related methods
US4766066A (en) * 1984-09-27 1988-08-23 Eli Lilly And Company Method of using bacteriophage lambda p1 promoter to produce a functional polypeptide in streptomyces
US5510238A (en) * 1984-10-26 1996-04-23 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Production of human T-cell leukemia (lymphotropic) retrovirus (HTLV-I) envelope protein fragments in bacteria and use in seroepidemiological studies
ATE73856T1 (de) 1984-12-21 1992-04-15 Biogen Inc Reinigung, herstellung und verwendung von tumor- nekrosisfaktoren.
US5182196A (en) * 1985-10-09 1993-01-26 Biogen, Inc. Expression systems for overproduction of desired proteins
ATE123526T1 (de) * 1987-08-17 1995-06-15 Hoffmann La Roche Hochreprimierbare expressionskontrollsequenzen.
JP2003204783A (ja) * 1999-07-19 2003-07-22 Ajinomoto Co Inc 発酵法による目的物質の製造法
US7579005B2 (en) 2005-11-28 2009-08-25 E. I. Du Pont De Nemours And Company Process for recombinant expression and purification of antimicrobial peptides using periplasmic targeting signals as precipitable hydrophobic tags

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU45104B (en) * 1980-04-03 1992-03-10 Biogen Nv Process for producing recombinant dnk molecule, capable of inducting polypeptide expression in an one-cell host
AU547096B2 (en) * 1980-05-12 1985-10-03 Biogen N.V. Foot-and mouth disease viral antigens

Also Published As

Publication number Publication date
YU87581A (en) 1984-04-30
JPH0838179A (ja) 1996-02-13
KR860001557B1 (ko) 1986-10-04
IE810757L (en) 1981-12-06
KR830005353A (ko) 1983-08-13
JP2001136966A (ja) 2001-05-22
JPH0838176A (ja) 1996-02-13
ES500967A0 (es) 1983-01-16
JP3158953B2 (ja) 2001-04-23
JPH0787785B2 (ja) 1995-09-27
BR8101972A (pt) 1982-08-17
IL62553A (en) 1984-12-31
DE3177298T2 (de) 1993-07-01
IL62553A0 (en) 1981-06-29
ES8302774A1 (es) 1983-01-16
EP0041767A2 (fr) 1981-12-16
EP0041767A3 (en) 1982-09-29
JP3158952B2 (ja) 2001-04-23
EP0041767B1 (fr) 1993-03-03
JP3158951B2 (ja) 2001-04-23
IE63126B1 (en) 1995-03-22
BG60443B2 (bg) 1995-03-31
DD158918A5 (de) 1983-02-09
PH22618A (en) 1988-10-28
DK171301B1 (da) 1996-08-26
JPS5714599A (en) 1982-01-25
CA1207251A (fr) 1986-07-08
JPH0838177A (ja) 1996-02-13
GR74282B (fr) 1984-06-21
DK148681A (da) 1981-12-07
JPH10304876A (ja) 1998-11-17
FI811009L (fi) 1981-12-07
DE3177298D1 (de) 1993-04-08

Similar Documents

Publication Publication Date Title
NO811119L (no) Forbedrede baerere, samt fremgangsmaate ved fremstilling av disse og for aa uttrykke klonede gener
US4758512A (en) Hosts and methods for producing recombinant products in high yields
EP0013828B1 (fr) ADN recombinant, hôtes transformés avec le dit-ADN recombinant et procédés pour la préparation des polypeptides
US7635466B1 (en) DNA sequences, recombinant DNA molecules and processes for producing human fibroblast interferon-like polypeptides
US5401642A (en) Vectors and methods for making such vectors and for expressing cloned genes
NO850733L (no) Alfa-type interferon
JPH07170978A (ja) レンニンの製造方法
DK159976B (da) Plasmidvektorer, fremgangsmaade til fremstilling deraf, bakterieceller transformeret med plasmidvektorer samt udtrykkelse af protein i transformerede bakterieceller
NO810986L (no) Bakteriell polypeptid-ekspresjon under anvendelse av tryptofon-promoter-operator
US4716112A (en) Vectors for increased expression of cloned genes
JP2579619B2 (ja) 組換えリシン毒素フラグメント
JP2905921B2 (ja) 細菌中に含まれるプラスミドの安定化方法
US5182196A (en) Expression systems for overproduction of desired proteins
JP2515488B2 (ja) ポリペプチドの製造方法
EP0179786B1 (fr) Vecteurs d'expression a nombre de reproduction eleve
JP2595205B2 (ja) 発現カセット
US4845031A (en) Recombinant DNA process for producing useful polypeptides
NO164664B (no) Rekombinante dna-molekyler som omfatter en dna-sekvens som koder for et polypeptid av interferon alpha (ifn-alfa) type.
HU196236B (en) Process for producing polypeptides showing hepatitis b virus antigenicity