NO333437B1 - Fremgangsmate for a isolere et intestinalt kolesterolbindende protein, sammensetning samt anvendelse av sammensetningen - Google Patents

Fremgangsmate for a isolere et intestinalt kolesterolbindende protein, sammensetning samt anvendelse av sammensetningen Download PDF

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Publication number
NO333437B1
NO333437B1 NO20051169A NO20051169A NO333437B1 NO 333437 B1 NO333437 B1 NO 333437B1 NO 20051169 A NO20051169 A NO 20051169A NO 20051169 A NO20051169 A NO 20051169A NO 333437 B1 NO333437 B1 NO 333437B1
Authority
NO
Norway
Prior art keywords
cholesterol
protein
compound
kda
biological material
Prior art date
Application number
NO20051169A
Other languages
English (en)
Norwegian (no)
Other versions
NO20051169L (no
Inventor
Wendelin Frick
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of NO20051169L publication Critical patent/NO20051169L/no
Publication of NO333437B1 publication Critical patent/NO333437B1/no

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO20051169A 2002-08-06 2005-03-04 Fremgangsmate for a isolere et intestinalt kolesterolbindende protein, sammensetning samt anvendelse av sammensetningen NO333437B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02017504 2002-08-06
PCT/EP2003/008290 WO2004014947A1 (en) 2002-08-06 2003-07-28 Method for isolating an intestinal cholesterol binding protein

Publications (2)

Publication Number Publication Date
NO20051169L NO20051169L (no) 2005-05-02
NO333437B1 true NO333437B1 (no) 2013-06-03

Family

ID=31502689

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20051169A NO333437B1 (no) 2002-08-06 2005-03-04 Fremgangsmate for a isolere et intestinalt kolesterolbindende protein, sammensetning samt anvendelse av sammensetningen
NO20130115A NO20130115L (no) 2002-08-06 2013-01-18 Farmasøytisk sammensetning omfattende et intestinalt kolesterolbindende protein.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20130115A NO20130115L (no) 2002-08-06 2013-01-18 Farmasøytisk sammensetning omfattende et intestinalt kolesterolbindende protein.

Country Status (17)

Country Link
US (2) US7435727B2 (es)
EP (1) EP1529061B1 (es)
JP (1) JP4575772B2 (es)
KR (1) KR101095288B1 (es)
CN (1) CN1330667C (es)
AT (1) ATE386053T1 (es)
AU (1) AU2003253341C1 (es)
BR (1) BR0313217A (es)
CA (1) CA2493487C (es)
DE (1) DE60319093T2 (es)
HK (1) HK1082509A1 (es)
IL (2) IL166492A (es)
MX (1) MXPA05001264A (es)
NO (2) NO333437B1 (es)
RU (1) RU2345089C2 (es)
WO (1) WO2004014947A1 (es)
ZA (1) ZA200500053B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0215579D0 (en) 2002-07-05 2002-08-14 Astrazeneca Ab Chemical compounds
US7135556B2 (en) 2002-07-19 2006-11-14 Schering Corporation NPC1L1 (NPC3) and methods of use thereof
US7871998B2 (en) 2003-12-23 2011-01-18 Astrazeneca Ab Diphenylazetidinone derivatives possessing cholesterol absorption inhibitory activity
MXPA06008124A (es) 2004-01-16 2007-01-26 Merck & Co Inc Npc1l1 (npc3) y metodos para identificar ligandos del mismo.
AU2006262441A1 (en) 2005-06-20 2007-01-04 Schering Corporation Piperidine derivatives useful as histamine H3 antagonists
SA06270191B1 (ar) 2005-06-22 2010-03-29 استرازينيكا ايه بي مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم
EP1986489A2 (en) 2006-02-24 2008-11-05 Schering Corporation Npc1l1 orthologues
TW200811098A (en) 2006-04-27 2008-03-01 Astrazeneca Ab Chemical compounds
CN1869704B (zh) * 2006-06-14 2010-06-30 厦门大学 快速鉴定与病原菌互作的宿主蛋白的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4710469A (en) * 1986-05-02 1987-12-01 Merck & Co., Inc. Novel phosphotyrosyl protein phosphatase
JP2893653B2 (ja) * 1988-11-10 1999-05-24 ジェネティックス・インスティテュート・インコーポレイテッド ナチュラルキラー細胞刺激因子
JPH06500991A (ja) 1990-05-16 1994-01-27 ジェネティックス・インスティテュート・インコーポレイテッド 骨および軟骨誘導蛋白質
US5264372A (en) * 1991-03-15 1993-11-23 Amylin Pharmaceuticals, Inc. Receptor-based screening methods for amylin agonists and antagonists
US5518911A (en) * 1995-01-06 1996-05-21 Onyx Pharmaceuticals, Inc. Human PAK65
JP3088681B2 (ja) * 1997-05-22 2000-09-18 宮城県 形質膜局在シアリダーゼ及びそれをコードするdna
US6383734B1 (en) * 1998-09-30 2002-05-07 Advanced Research And Technology Institute, Inc. Method to determine inhibition of PAK3 activation of Raf-1
JP2000166545A (ja) * 1998-12-07 2000-06-20 Snow Brand Milk Prod Co Ltd 胆汁酸活性化リパーゼ
WO2000060062A2 (en) 1999-04-01 2000-10-12 Astrazeneca Uk Limited Human signal transduction serine/threonine protein kinase
US6593078B1 (en) * 1999-04-16 2003-07-15 Schering Corporation Use of azetidinone compounds
DE10042447A1 (de) * 2000-08-29 2002-03-28 Aventis Pharma Gmbh Protein aus dem Darm von Wirbeltieren, welches Cholesterin absorbiert, sowie Verwendung dieses Proteins zur Identifizierung von Inhibitoren des intestinalen Cholesterintransports

Also Published As

Publication number Publication date
DE60319093D1 (de) 2008-03-27
NO20130115L (no) 2005-05-02
EP1529061A1 (en) 2005-05-11
AU2003253341B2 (en) 2009-04-23
JP4575772B2 (ja) 2010-11-04
JP2006512054A (ja) 2006-04-13
US7435727B2 (en) 2008-10-14
CN1330667C (zh) 2007-08-08
CA2493487C (en) 2013-01-22
WO2004014947A1 (en) 2004-02-19
AU2003253341C1 (en) 2009-09-24
RU2345089C2 (ru) 2009-01-27
KR20060015443A (ko) 2006-02-17
RU2005106238A (ru) 2005-08-27
US20040126812A1 (en) 2004-07-01
CA2493487A1 (en) 2004-02-19
US20080167451A1 (en) 2008-07-10
BR0313217A (pt) 2005-06-14
KR101095288B1 (ko) 2011-12-16
HK1082509A1 (en) 2006-06-09
IL166492A (en) 2010-12-30
IL166492A0 (en) 2006-01-15
MXPA05001264A (es) 2005-04-28
DE60319093T2 (de) 2009-02-05
IL199409A (en) 2010-12-30
CN1668642A (zh) 2005-09-14
NO20051169L (no) 2005-05-02
ZA200500053B (en) 2006-07-26
AU2003253341A1 (en) 2004-02-25
EP1529061B1 (en) 2008-02-13
ATE386053T1 (de) 2008-03-15
US7786103B2 (en) 2010-08-31

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