BR0313217A - Método para isolar uma protéina de ligação do colesterol intestinal - Google Patents

Método para isolar uma protéina de ligação do colesterol intestinal

Info

Publication number
BR0313217A
BR0313217A BR0313217-0A BR0313217A BR0313217A BR 0313217 A BR0313217 A BR 0313217A BR 0313217 A BR0313217 A BR 0313217A BR 0313217 A BR0313217 A BR 0313217A
Authority
BR
Brazil
Prior art keywords
isolating
binding protein
intestinal cholesterol
cholesterol binding
intestinal
Prior art date
Application number
BR0313217-0A
Other languages
English (en)
Inventor
Werner Kramer
Wendelin Frick
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of BR0313217A publication Critical patent/BR0313217A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

"MéTODO PARA ISOLAR UMA PROTEìNA DE LIGAçãO DO COLESTEROL INTESTINAL". A presente invenção refere-se a um método para isolar uma proteína intestinal a qual é capaz de ligar colesterol e/ou inibidores da absorção do colesterol.
BR0313217-0A 2002-08-06 2003-07-28 Método para isolar uma protéina de ligação do colesterol intestinal BR0313217A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02017504 2002-08-06
PCT/EP2003/008290 WO2004014947A1 (en) 2002-08-06 2003-07-28 Method for isolating an intestinal cholesterol binding protein

Publications (1)

Publication Number Publication Date
BR0313217A true BR0313217A (pt) 2005-06-14

Family

ID=31502689

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0313217-0A BR0313217A (pt) 2002-08-06 2003-07-28 Método para isolar uma protéina de ligação do colesterol intestinal

Country Status (17)

Country Link
US (2) US7435727B2 (pt)
EP (1) EP1529061B1 (pt)
JP (1) JP4575772B2 (pt)
KR (1) KR101095288B1 (pt)
CN (1) CN1330667C (pt)
AT (1) ATE386053T1 (pt)
AU (1) AU2003253341C1 (pt)
BR (1) BR0313217A (pt)
CA (1) CA2493487C (pt)
DE (1) DE60319093T2 (pt)
HK (1) HK1082509A1 (pt)
IL (2) IL166492A (pt)
MX (1) MXPA05001264A (pt)
NO (2) NO333437B1 (pt)
RU (1) RU2345089C2 (pt)
WO (1) WO2004014947A1 (pt)
ZA (1) ZA200500053B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0215579D0 (en) 2002-07-05 2002-08-14 Astrazeneca Ab Chemical compounds
US7135556B2 (en) 2002-07-19 2006-11-14 Schering Corporation NPC1L1 (NPC3) and methods of use thereof
DE602004029715D1 (de) 2003-12-23 2010-12-02 Astrazeneca Ab Diphenylazetidinonderivate mit die cholesterinabsorption hemmender wirkung
JP4590417B2 (ja) 2004-01-16 2010-12-01 メルク・シャープ・エンド・ドーム・コーポレイション Ｎｐｃ１ｌ１（ｎｐｃ３）およびこのリガンドの同定方法
JP2008546784A (ja) 2005-06-20 2008-12-25 シェーリング コーポレイション ヒスタミンｈ３アンタゴニストとして有用なピペリジン誘導体
SA06270191B1 (ar) 2005-06-22 2010-03-29 استرازينيكا ايه بي مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم
WO2007100807A2 (en) 2006-02-24 2007-09-07 Schering Corporation Npc1l1 orthologues
AR060623A1 (es) 2006-04-27 2008-07-02 Astrazeneca Ab Compuestos derivados de 2-azetidinona y un metodo de preparacion
CN1869704B (zh) * 2006-06-14 2010-06-30 厦门大学 快速鉴定与病原菌互作的宿主蛋白的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4710469A (en) * 1986-05-02 1987-12-01 Merck & Co., Inc. Novel phosphotyrosyl protein phosphatase
ATE140483T1 (de) * 1988-11-10 1996-08-15 Genetics Inst Natürlicher killerzellen-stimulationsfaktor
ATE209251T1 (de) 1990-05-16 2001-12-15 Genetics Inst Knochen- und knorpel-bildung hervorrufende proteine
US5264372A (en) * 1991-03-15 1993-11-23 Amylin Pharmaceuticals, Inc. Receptor-based screening methods for amylin agonists and antagonists
US5518911A (en) * 1995-01-06 1996-05-21 Onyx Pharmaceuticals, Inc. Human PAK65
JP3088681B2 (ja) * 1997-05-22 2000-09-18 宮城県 形質膜局在シアリダーゼ及びそれをコードするｄｎａ
US6383734B1 (en) * 1998-09-30 2002-05-07 Advanced Research And Technology Institute, Inc. Method to determine inhibition of PAK3 activation of Raf-1
JP2000166545A (ja) * 1998-12-07 2000-06-20 Snow Brand Milk Prod Co Ltd 胆汁酸活性化リパーゼ
AU3566200A (en) 1999-04-01 2000-10-23 Astrazeneca Uk Limited Human signal transduction serine/threonine protein kinase
WO2000063703A1 (en) * 1999-04-16 2000-10-26 Schering Corporation Use of azetidinone compounds
DE10042447A1 (de) * 2000-08-29 2002-03-28 Aventis Pharma Gmbh Protein aus dem Darm von Wirbeltieren, welches Cholesterin absorbiert, sowie Verwendung dieses Proteins zur Identifizierung von Inhibitoren des intestinalen Cholesterintransports

Also Published As

Publication number Publication date
JP2006512054A (ja) 2006-04-13
US7786103B2 (en) 2010-08-31
CA2493487A1 (en) 2004-02-19
CA2493487C (en) 2013-01-22
NO20051169L (no) 2005-05-02
IL199409A (en) 2010-12-30
RU2345089C2 (ru) 2009-01-27
KR101095288B1 (ko) 2011-12-16
ATE386053T1 (de) 2008-03-15
RU2005106238A (ru) 2005-08-27
WO2004014947A1 (en) 2004-02-19
EP1529061A1 (en) 2005-05-11
KR20060015443A (ko) 2006-02-17
NO333437B1 (no) 2013-06-03
US20040126812A1 (en) 2004-07-01
US20080167451A1 (en) 2008-07-10
CN1668642A (zh) 2005-09-14
IL166492A0 (en) 2006-01-15
AU2003253341C1 (en) 2009-09-24
US7435727B2 (en) 2008-10-14
CN1330667C (zh) 2007-08-08
AU2003253341B2 (en) 2009-04-23
EP1529061B1 (en) 2008-02-13
MXPA05001264A (es) 2005-04-28
DE60319093T2 (de) 2009-02-05
AU2003253341A1 (en) 2004-02-25
DE60319093D1 (de) 2008-03-27
JP4575772B2 (ja) 2010-11-04
HK1082509A1 (en) 2006-06-09
IL166492A (en) 2010-12-30
ZA200500053B (en) 2006-07-26
NO20130115L (no) 2005-05-02

Similar Documents

Publication Publication Date Title
HK1082509A1 (en) Method for isolating an intestinal cholesterol binding protein
NO20052547D0 (no) System og fremgangsmate for foretrukken applikasjonsinstallasjon og -eksekvering.
CA2545989A1 (en) Method and device for purifying nucleic acids
DE60321162D1 (de) Text-zu-sprache für handgeräte
DE60304628D1 (de) Gaspedalanordnung und Verfahren zum Einstellen von dessen Reaktionskraft
DE60325210D1 (de) Verfahren und systeme zur bereitstellung von ergänzendem kontextinhalt
DE60226797D1 (de) Instrument zum Einbringen von Befestigungselementen für Transplantate
IL150855A0 (en) Intratubular anastomosis apparatus
NO20071309L (no) Fremgangsmate for ekspansjon
WO2008030892A3 (en) Drug design for tubulin inhibitors, compositions, and methods of treatment thereof
AU2002210446A1 (en) Protein extracted from the intestines of vertebrates, which absorbs cholesterol, and the use of this protein for identifying inhibitors of intestinal cholesterol transport
ATE514673T1 (de) Verfahren zur trennung von pentennitril-isomeren
DE602006018035D1 (de) Verfahren und kit zur quantitativen bestimmung von small, dense ldl cholesterol
ATA19522003A (de) Gag-bindungsproteine
EP1909602A4 (en) SYSTEMS AND METHOD FOR SEPARATING PROTEINS FROM COMPOUND FABRICS
BRPI0417992B8 (pt) métodos para purificar fsh humano recombinante ou uma variante de fsh
BR0204916B1 (pt) mÉtodo para produzir uma olefina.
NO20043705L (no) System og fremgangsmate for kjoring av foring
DE60319959D1 (de) Verfahren zur härtung von cyanoacrylat-klebstoffen
DE602004022042D1 (de) Verfahren und kit zur identifizierung antibiotikaresistenter mikroorganismen
DE602004004334D1 (de) Bearbeitungsverfahren zur Bearbeitung von gewölbten Oberflächen
AU2003290735A1 (en) Inhibitors of monoamine uptake
WO2004024082A3 (en) Highly specific modulators of gtpases for target validation
AU2003304409A8 (en) Evaluating protein signatures
DE602004016193D1 (de) Verfahren zur bekämpfung von unkräutern

Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: SANOFI-AVENTIS DEUTSCHLAND GMBH (DE)

Free format text: ALTERADO DE: AVENTIS PHARMA DEUTSCHLAND GMBH

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2316 DE 26-05-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.