BR0313217A - Method for Isolating an Intestinal Cholesterol Binding Protein - Google Patents

Method for Isolating an Intestinal Cholesterol Binding Protein

Info

Publication number
BR0313217A
BR0313217A BR0313217-0A BR0313217A BR0313217A BR 0313217 A BR0313217 A BR 0313217A BR 0313217 A BR0313217 A BR 0313217A BR 0313217 A BR0313217 A BR 0313217A
Authority
BR
Brazil
Prior art keywords
isolating
binding protein
intestinal cholesterol
cholesterol binding
intestinal
Prior art date
Application number
BR0313217-0A
Other languages
Portuguese (pt)
Inventor
Werner Kramer
Wendelin Frick
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of BR0313217A publication Critical patent/BR0313217A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention describes a method for isolating an intestinal protein which is able to bind cholesterol and/or cholesterol uptake inhibitors.
BR0313217-0A 2002-08-06 2003-07-28 Method for Isolating an Intestinal Cholesterol Binding Protein BR0313217A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02017504 2002-08-06
PCT/EP2003/008290 WO2004014947A1 (en) 2002-08-06 2003-07-28 Method for isolating an intestinal cholesterol binding protein

Publications (1)

Publication Number Publication Date
BR0313217A true BR0313217A (en) 2005-06-14

Family

ID=31502689

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0313217-0A BR0313217A (en) 2002-08-06 2003-07-28 Method for Isolating an Intestinal Cholesterol Binding Protein

Country Status (17)

Country Link
US (2) US7435727B2 (en)
EP (1) EP1529061B1 (en)
JP (1) JP4575772B2 (en)
KR (1) KR101095288B1 (en)
CN (1) CN1330667C (en)
AT (1) ATE386053T1 (en)
AU (1) AU2003253341C1 (en)
BR (1) BR0313217A (en)
CA (1) CA2493487C (en)
DE (1) DE60319093T2 (en)
HK (1) HK1082509A1 (en)
IL (2) IL166492A (en)
MX (1) MXPA05001264A (en)
NO (2) NO333437B1 (en)
RU (1) RU2345089C2 (en)
WO (1) WO2004014947A1 (en)
ZA (1) ZA200500053B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0215579D0 (en) 2002-07-05 2002-08-14 Astrazeneca Ab Chemical compounds
US7135556B2 (en) 2002-07-19 2006-11-14 Schering Corporation NPC1L1 (NPC3) and methods of use thereof
WO2005061452A1 (en) 2003-12-23 2005-07-07 Astrazeneca Ab Diphenylazetidinone derivates possessing cholesterol absorption inhibitory activity
US7901893B2 (en) 2004-01-16 2011-03-08 Merck Sharp & Dohme Corp. NPC1L1 (NPC3) and methods of identifying ligands thereof
KR20080021082A (en) 2005-06-20 2008-03-06 쉐링 코포레이션 Piperidine derivatives useful as histamine h3 antagonists
SA06270191B1 (en) 2005-06-22 2010-03-29 استرازينيكا ايه بي Novel 2-Azetidinone Derivatives as Cholesterol Absorption Inhibitors for the Treatment of Hyperlipidaemic Conditions
WO2007100807A2 (en) 2006-02-24 2007-09-07 Schering Corporation Npc1l1 orthologues
TW200811098A (en) 2006-04-27 2008-03-01 Astrazeneca Ab Chemical compounds
CN1869704B (en) * 2006-06-14 2010-06-30 厦门大学 Method for quickly determining host protein interaction with pathogenic bacteria

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4710469A (en) 1986-05-02 1987-12-01 Merck & Co., Inc. Novel phosphotyrosyl protein phosphatase
ATE140483T1 (en) 1988-11-10 1996-08-15 Genetics Inst NATURAL KILLER CELL STIMULATION FACTOR
ES2168091T3 (en) * 1990-05-16 2002-06-01 Genetics Inst OSEA AND CARTILAGINOUS INDUCTION PROTEINS.
US5264372A (en) * 1991-03-15 1993-11-23 Amylin Pharmaceuticals, Inc. Receptor-based screening methods for amylin agonists and antagonists
US5518911A (en) * 1995-01-06 1996-05-21 Onyx Pharmaceuticals, Inc. Human PAK65
JP3088681B2 (en) * 1997-05-22 2000-09-18 宮城県 Plasma membrane-localized sialidase and DNA encoding the same
US6383734B1 (en) * 1998-09-30 2002-05-07 Advanced Research And Technology Institute, Inc. Method to determine inhibition of PAK3 activation of Raf-1
JP2000166545A (en) * 1998-12-07 2000-06-20 Snow Brand Milk Prod Co Ltd Bile salt-activated lipase
WO2000060062A2 (en) 1999-04-01 2000-10-12 Astrazeneca Uk Limited Human signal transduction serine/threonine protein kinase
US6593078B1 (en) * 1999-04-16 2003-07-15 Schering Corporation Use of azetidinone compounds
DE10042447A1 (en) * 2000-08-29 2002-03-28 Aventis Pharma Gmbh Vertebrate intestinal protein that absorbs cholesterol and use of this protein to identify inhibitors of intestinal cholesterol transport

Also Published As

Publication number Publication date
RU2005106238A (en) 2005-08-27
CN1668642A (en) 2005-09-14
IL199409A (en) 2010-12-30
JP2006512054A (en) 2006-04-13
JP4575772B2 (en) 2010-11-04
NO333437B1 (en) 2013-06-03
US20080167451A1 (en) 2008-07-10
ATE386053T1 (en) 2008-03-15
CA2493487C (en) 2013-01-22
KR101095288B1 (en) 2011-12-16
NO20051169L (en) 2005-05-02
US7435727B2 (en) 2008-10-14
IL166492A0 (en) 2006-01-15
MXPA05001264A (en) 2005-04-28
WO2004014947A1 (en) 2004-02-19
AU2003253341B2 (en) 2009-04-23
CA2493487A1 (en) 2004-02-19
NO20130115L (en) 2005-05-02
EP1529061B1 (en) 2008-02-13
HK1082509A1 (en) 2006-06-09
IL166492A (en) 2010-12-30
KR20060015443A (en) 2006-02-17
EP1529061A1 (en) 2005-05-11
US7786103B2 (en) 2010-08-31
CN1330667C (en) 2007-08-08
ZA200500053B (en) 2006-07-26
DE60319093T2 (en) 2009-02-05
RU2345089C2 (en) 2009-01-27
US20040126812A1 (en) 2004-07-01
AU2003253341C1 (en) 2009-09-24
AU2003253341A1 (en) 2004-02-25
DE60319093D1 (en) 2008-03-27

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: SANOFI-AVENTIS DEUTSCHLAND GMBH (DE)

Free format text: ALTERADO DE: AVENTIS PHARMA DEUTSCHLAND GMBH

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2316 DE 26-05-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.