NO332089B1 - Anvendelse av et 7ß-hydroksysteroid eller en farmasoytisk aksepterbar ester eller et annet derivat for fremstilling av et medikament for beskyttelse mot neuronskade - Google Patents

Anvendelse av et 7ß-hydroksysteroid eller en farmasoytisk aksepterbar ester eller et annet derivat for fremstilling av et medikament for beskyttelse mot neuronskade Download PDF

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Publication number
NO332089B1
NO332089B1 NO20026244A NO20026244A NO332089B1 NO 332089 B1 NO332089 B1 NO 332089B1 NO 20026244 A NO20026244 A NO 20026244A NO 20026244 A NO20026244 A NO 20026244A NO 332089 B1 NO332089 B1 NO 332089B1
Authority
NO
Norway
Prior art keywords
group
carbon atoms
groups
hydroxy
atoms
Prior art date
Application number
NO20026244A
Other languages
English (en)
Norwegian (no)
Other versions
NO20026244D0 (no
NO20026244L (no
Inventor
Ernst Wuelfert
Ashley Ker Pringle
Lars Eric Sundstrom
Original Assignee
Hunter Fleming Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hunter Fleming Ltd filed Critical Hunter Fleming Ltd
Publication of NO20026244D0 publication Critical patent/NO20026244D0/no
Publication of NO20026244L publication Critical patent/NO20026244L/no
Publication of NO332089B1 publication Critical patent/NO332089B1/no

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO20026244A 2000-06-29 2002-12-27 Anvendelse av et 7ß-hydroksysteroid eller en farmasoytisk aksepterbar ester eller et annet derivat for fremstilling av et medikament for beskyttelse mot neuronskade NO332089B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0016027A GB2363984A (en) 2000-06-29 2000-06-29 Protection against neuronal damage using 3-hydroxy-7 -hydroxy steroids and 3-oxo-7 -hydroxy steroids
PCT/GB2001/002929 WO2002000224A1 (en) 2000-06-29 2001-06-29 Neuroprotective 7-beta-hydroxysteroids

Publications (3)

Publication Number Publication Date
NO20026244D0 NO20026244D0 (no) 2002-12-27
NO20026244L NO20026244L (no) 2003-02-27
NO332089B1 true NO332089B1 (no) 2012-06-18

Family

ID=9894710

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20026244A NO332089B1 (no) 2000-06-29 2002-12-27 Anvendelse av et 7ß-hydroksysteroid eller en farmasoytisk aksepterbar ester eller et annet derivat for fremstilling av et medikament for beskyttelse mot neuronskade

Country Status (23)

Country Link
US (2) US20030186953A1 (cs)
EP (1) EP1294381B1 (cs)
JP (1) JP2004501195A (cs)
KR (1) KR100829490B1 (cs)
CN (1) CN100441189C (cs)
AT (1) ATE303152T1 (cs)
AU (2) AU6770501A (cs)
CA (1) CA2414583C (cs)
CY (1) CY1105371T1 (cs)
CZ (1) CZ305306B6 (cs)
DE (1) DE60113112T2 (cs)
DK (1) DK1294381T3 (cs)
ES (1) ES2247141T3 (cs)
GB (1) GB2363984A (cs)
HK (1) HK1052299B (cs)
HU (1) HU229265B1 (cs)
IL (2) IL153540A0 (cs)
NO (1) NO332089B1 (cs)
PL (1) PL200698B1 (cs)
RU (1) RU2258511C2 (cs)
SI (1) SI1294381T1 (cs)
WO (1) WO2002000224A1 (cs)
ZA (1) ZA200210214B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2363983A (en) 2000-06-29 2002-01-16 Hunter Fleming Ltd Protection against neuronal damage using 7-hydroxyepiandrosterone
GB2378898A (en) 2001-08-14 2003-02-26 Hunter Fleming Ltd Prophylactic and therapeutic use of hydroxysteroids
CA2496867A1 (en) * 2002-08-28 2004-03-11 Hollis-Eden Pharmaceuticals, Inc. Therapeutic treatment methods
GB0409498D0 (en) * 2004-04-28 2004-06-02 Hunter Fleming Ltd Transdermal steroid formulation
US7910755B2 (en) * 2004-09-29 2011-03-22 Harbor Biosciences, Inc. Stem cell expansion and uses
CN101102767A (zh) * 2004-11-23 2008-01-09 细胞基因公司 用jnk抑制剂治疗和控制中枢神经系统损伤的方法和组合物
BR122013033954B8 (pt) 2006-11-21 2021-05-25 Umecrine Ab novos esteróides apresentando solubilidade em água e resistência contra metabolismo aumentadas, e métodos para sua produção
MX2009005753A (es) 2006-11-30 2009-09-28 Hunter Fleming Ltd Modulacion de trayectorias metabolicas de prostaglandina/ciclooxig enasa.
GB0623971D0 (en) * 2006-11-30 2007-01-10 Hunter Fleming Ltd Modulation of prostaglandin/cyclooxygenase metabolic pathways
CZ2008434A3 (cs) * 2008-07-10 2009-12-09 Ústav organické chemie a biochemie Akademie ved CR, v. v. i. Pregnanové anionické slouceniny, zpusob jejich výroby a jejich použití
CU20110244A7 (es) 2011-12-27 2013-08-29 Ct De Investigación Y Desarrollo De Medicamentos Cidem Sistemas espiroesteroidales con efectos neuroactivos y anti-inflamatorios
DE102012001361A1 (de) 2012-01-24 2013-07-25 Linde Aktiengesellschaft Verfahren zum Kaltgasspritzen
US20160362442A1 (en) * 2015-06-10 2016-12-15 IronMag Labs Method For DHEA Enanthate Processing

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292730A (en) * 1990-08-29 1994-03-08 Humanetics Corporation Modulation of immune system with Δ5-androstenes
FR2696934B1 (fr) * 1992-10-20 1995-06-02 Conservatoire Nal Arts Metiers Dérivés de stéroïdes naturels 3B hydroxyles ayant des propriétés de déclenchement et de stimulation de l'immunité, composition les contenant et procédé pour les obtenir.
CA2153895A1 (en) * 1993-03-09 1994-09-15 Raymond A. Daynes Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome
EP0837874B1 (en) * 1995-06-06 2004-12-15 Euro-Celtique S.A. Neuroactive steroids of the androstane and pregnane series
GB2317826B (en) * 1995-08-29 1999-12-15 Univ Edinburgh Regulation of intracellular glucocorticoid concentrations
US5985242A (en) * 1995-10-27 1999-11-16 Praecis Pharmaceuticals, Inc. Modulators of β-amyloid peptide aggregation comprising D-amino acids
CN1222851A (zh) * 1996-04-09 1999-07-14 英国技术集团国际有限公司 7α-取代的类固醇用于治疗神经精神病、免疫或内分泌疾病的用途
DE69737791D1 (de) * 1996-04-09 2007-07-19 Univ Edinburgh Verwendung von 7-alpha-substituierten steroiden zur behandlung von neuropsychiatrischen erkrankungen
DK0929574T3 (da) * 1996-08-27 2005-10-31 Praecis Pharm Inc Modulatorer af beta-amyloidpeptidaggregering, som omfatter D-aminosyrer
RU2142802C1 (ru) * 1997-02-13 1999-12-20 Обут Тимофей Александрович Гипотензивное средство
US6544972B1 (en) * 1997-09-25 2003-04-08 Regents Of The University Of Minnesota Methods of limiting apoptosis of cells
WO1999024400A1 (en) * 1997-11-10 1999-05-20 Vyrex Corporation Probucol esters and uses thereof
CA2309855A1 (en) * 1997-11-24 1999-06-03 Katherine D. Gordon Testosterone inhibitors and use for the protection of neurons
AU3467699A (en) * 1998-04-14 1999-11-01 Pharmadigm, Inc. Method for reducing central nervous system impairment
US6667299B1 (en) * 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
DE50014299D1 (de) * 1999-11-02 2007-06-14 Bayer Schering Pharma Ag 18-nor-steroide als selektiv wirksame estrogene
GB0003524D0 (en) * 2000-02-15 2000-04-05 Btg Int Ltd Cytoprotective steroids (II)
GB2363983A (en) * 2000-06-29 2002-01-16 Hunter Fleming Ltd Protection against neuronal damage using 7-hydroxyepiandrosterone

Also Published As

Publication number Publication date
WO2002000224A1 (en) 2002-01-03
HK1052299B (en) 2006-01-27
US20100130459A1 (en) 2010-05-27
ES2247141T3 (es) 2006-03-01
ATE303152T1 (de) 2005-09-15
PL359105A1 (en) 2004-08-23
NO20026244D0 (no) 2002-12-27
HUP0301317A2 (hu) 2003-08-28
JP2004501195A (ja) 2004-01-15
DK1294381T3 (da) 2005-10-31
CN1443071A (zh) 2003-09-17
US20030186953A1 (en) 2003-10-02
DE60113112D1 (de) 2005-10-06
IL153540A (en) 2008-07-08
AU2001267705B2 (en) 2005-08-18
EP1294381A1 (en) 2003-03-26
GB0016027D0 (en) 2000-08-23
ZA200210214B (en) 2004-03-17
AU6770501A (en) 2002-01-08
CA2414583A1 (en) 2002-01-03
CY1105371T1 (el) 2010-04-28
NO20026244L (no) 2003-02-27
SI1294381T1 (sl) 2006-04-30
RU2258511C2 (ru) 2005-08-20
DE60113112T2 (de) 2006-07-13
EP1294381B1 (en) 2005-08-31
KR20030034112A (ko) 2003-05-01
HUP0301317A3 (en) 2006-06-28
HK1052299A1 (en) 2003-09-11
GB2363984A (en) 2002-01-16
IL153540A0 (en) 2003-07-06
CN100441189C (zh) 2008-12-10
PL200698B1 (pl) 2009-01-30
HU229265B1 (en) 2013-10-28
KR100829490B1 (ko) 2008-05-16
CA2414583C (en) 2010-08-24
CZ305306B6 (cs) 2015-07-22

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US20100173883A1 (en) 7-hydroxyepiandrosterone having neuroprotective activity
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