NO329956B1 - Nye insulinanaloger med okt sinkbinding og forloper til denne, fremgangsmate for fremstilling, DNA sekvens, ekspresjonsvektor og isolert vertscelle, insulin-sink-kompleks, farmasoytisk preparat, injiserbar opplosning og anvendelse av insulinanalogene. - Google Patents
Nye insulinanaloger med okt sinkbinding og forloper til denne, fremgangsmate for fremstilling, DNA sekvens, ekspresjonsvektor og isolert vertscelle, insulin-sink-kompleks, farmasoytisk preparat, injiserbar opplosning og anvendelse av insulinanalogene. Download PDFInfo
- Publication number
- NO329956B1 NO329956B1 NO20006177A NO20006177A NO329956B1 NO 329956 B1 NO329956 B1 NO 329956B1 NO 20006177 A NO20006177 A NO 20006177A NO 20006177 A NO20006177 A NO 20006177A NO 329956 B1 NO329956 B1 NO 329956B1
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- Prior art keywords
- insulin
- gly
- leu
- ala
- glu
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19825447A DE19825447A1 (de) | 1998-06-06 | 1998-06-06 | Neue Insulinanaloga mit erhöhter Zinkbildung |
PCT/EP1999/003490 WO1999064598A2 (de) | 1998-06-06 | 1999-05-21 | Neue insulinanaloga mit erhöhter zinkbindung |
Publications (3)
Publication Number | Publication Date |
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NO20006177D0 NO20006177D0 (no) | 2000-12-05 |
NO20006177L NO20006177L (no) | 2000-12-05 |
NO329956B1 true NO329956B1 (no) | 2011-01-31 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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NO20006177A NO329956B1 (no) | 1998-06-06 | 2000-12-05 | Nye insulinanaloger med okt sinkbinding og forloper til denne, fremgangsmate for fremstilling, DNA sekvens, ekspresjonsvektor og isolert vertscelle, insulin-sink-kompleks, farmasoytisk preparat, injiserbar opplosning og anvendelse av insulinanalogene. |
Country Status (24)
Country | Link |
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US (1) | US6686177B1 (hu) |
EP (1) | EP1084248B1 (hu) |
JP (1) | JP4402296B2 (hu) |
KR (1) | KR100649339B1 (hu) |
CN (1) | CN1304450B (hu) |
AR (1) | AR019852A1 (hu) |
AT (1) | ATE334201T1 (hu) |
AU (1) | AU757275B2 (hu) |
BR (1) | BR9910978A (hu) |
CA (1) | CA2330183C (hu) |
CZ (1) | CZ301377B6 (hu) |
DE (2) | DE19825447A1 (hu) |
DK (1) | DK1084248T3 (hu) |
ES (1) | ES2268871T3 (hu) |
HK (1) | HK1036808A1 (hu) |
HU (1) | HU228908B1 (hu) |
MX (1) | MXPA00011456A (hu) |
NO (1) | NO329956B1 (hu) |
PL (1) | PL198190B1 (hu) |
PT (1) | PT1084248E (hu) |
RU (1) | RU2225723C2 (hu) |
TR (1) | TR200003606T2 (hu) |
WO (1) | WO1999064598A2 (hu) |
ZA (1) | ZA200006835B (hu) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19825447A1 (de) * | 1998-06-06 | 1999-12-09 | Hoechst Marion Roussel De Gmbh | Neue Insulinanaloga mit erhöhter Zinkbildung |
AU2002248464A1 (en) | 2001-02-21 | 2002-09-12 | Medtronic Minimed, Inc. | Stabilized insulin formulations |
US20040038864A1 (en) * | 2002-06-27 | 2004-02-26 | Per Balschmidt | Use of dimethyl sulfone as isotonicity agent |
CN101027318B (zh) | 2004-07-19 | 2016-05-25 | 比奥孔有限公司 | 胰岛素-低聚物共轭物,制剂及其用途 |
US7833513B2 (en) | 2004-12-03 | 2010-11-16 | Rhode Island Hospital | Treatment of Alzheimer's Disease |
WO2009050738A2 (en) * | 2007-10-16 | 2009-04-23 | Biocon Limited | An orally administerable solid pharmaceutical composition and a process thereof |
JP5241849B2 (ja) * | 2007-11-16 | 2013-07-17 | ノボ・ノルデイスク・エー/エス | インスリン及びインスリン分泌性ペプチドを含む薬学的組成物 |
PL219335B1 (pl) * | 2008-07-04 | 2015-04-30 | Inst Biotechnologii I Antybiotyków | Pochodna insuliny lub jej farmaceutycznie dopuszczalna sól, jej zastosowanie oraz zawierająca ją kompozycja farmaceutyczna |
RU2555557C2 (ru) * | 2008-07-31 | 2015-07-10 | Кейз Вестерн Ризев Юнивесити | Инсулин, стабилизированный галогеном |
WO2011103575A1 (en) * | 2010-02-22 | 2011-08-25 | Case Western Reserve University | Long-acting insulin analogue preparations in soluble and crystalline forms |
PL222975B1 (pl) | 2012-05-23 | 2016-09-30 | Inst Biotechnologii I Antybiotyków | Analog insuliny lub jego farmaceutycznie dopuszczalna sól, kompozycja farmaceutyczna o przedłużonym działaniu terapeutycznym oraz zastosowanie analogu insuliny |
FR3013049B1 (fr) | 2013-11-14 | 2015-11-13 | You-Ping Chan | Analogue de l'insuline glargine |
WO2016144658A1 (en) * | 2015-03-10 | 2016-09-15 | Merck Sharp & Dohme Corp. | Process for preparing recombinant insulin using microfiltration |
UY36870A (es) * | 2015-08-28 | 2017-03-31 | Hanmi Pharm Ind Co Ltd | Análogos de insulina novedosos |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
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FI78616C (fi) | 1982-02-05 | 1989-09-11 | Novo Industri As | Foerfarande foer framstaellning av en foer infusionsaendamaol avsedd stabiliserad insulinloesning, som har en foerhoejd zinkhalt. |
DE3326472A1 (de) | 1983-07-22 | 1985-02-14 | Hoechst Ag, 6230 Frankfurt | Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus |
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-
1998
- 1998-06-06 DE DE19825447A patent/DE19825447A1/de not_active Withdrawn
-
1999
- 1999-05-21 US US09/701,968 patent/US6686177B1/en not_active Expired - Lifetime
- 1999-05-21 AU AU41454/99A patent/AU757275B2/en not_active Ceased
- 1999-05-21 DE DE59913711T patent/DE59913711D1/de not_active Expired - Lifetime
- 1999-05-21 PT PT99925023T patent/PT1084248E/pt unknown
- 1999-05-21 DK DK99925023T patent/DK1084248T3/da active
- 1999-05-21 PL PL345898A patent/PL198190B1/pl unknown
- 1999-05-21 CZ CZ20004525A patent/CZ301377B6/cs not_active IP Right Cessation
- 1999-05-21 AT AT99925023T patent/ATE334201T1/de active
- 1999-05-21 MX MXPA00011456A patent/MXPA00011456A/es not_active IP Right Cessation
- 1999-05-21 CN CN998070688A patent/CN1304450B/zh not_active Expired - Fee Related
- 1999-05-21 CA CA002330183A patent/CA2330183C/en not_active Expired - Fee Related
- 1999-05-21 EP EP99925023A patent/EP1084248B1/de not_active Expired - Lifetime
- 1999-05-21 BR BR9910978-6A patent/BR9910978A/pt active Search and Examination
- 1999-05-21 ES ES99925023T patent/ES2268871T3/es not_active Expired - Lifetime
- 1999-05-21 TR TR2000/03606T patent/TR200003606T2/xx unknown
- 1999-05-21 KR KR1020007013862A patent/KR100649339B1/ko not_active IP Right Cessation
- 1999-05-21 WO PCT/EP1999/003490 patent/WO1999064598A2/de active IP Right Grant
- 1999-05-21 HU HU0102217A patent/HU228908B1/hu not_active IP Right Cessation
- 1999-05-21 JP JP2000553588A patent/JP4402296B2/ja not_active Expired - Fee Related
- 1999-05-21 RU RU2001101164/15A patent/RU2225723C2/ru not_active IP Right Cessation
- 1999-06-03 AR ARP990102631A patent/AR019852A1/es active IP Right Grant
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2000
- 2000-11-22 ZA ZA200006835A patent/ZA200006835B/xx unknown
- 2000-12-05 NO NO20006177A patent/NO329956B1/no not_active IP Right Cessation
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2001
- 2001-11-06 HK HK01107736.3A patent/HK1036808A1/xx not_active IP Right Cessation
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