NO328575B1 - Anvendelse av suberoylanilidhydroksyaminsyre (SAHA) for fremstilling av et oralt medikament for behandling av mesoteliom - Google Patents
Anvendelse av suberoylanilidhydroksyaminsyre (SAHA) for fremstilling av et oralt medikament for behandling av mesoteliom Download PDFInfo
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- NO328575B1 NO328575B1 NO20061348A NO20061348A NO328575B1 NO 328575 B1 NO328575 B1 NO 328575B1 NO 20061348 A NO20061348 A NO 20061348A NO 20061348 A NO20061348 A NO 20061348A NO 328575 B1 NO328575 B1 NO 328575B1
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Prostheses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (3)
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US10/650,025 US7148257B2 (en) | 2002-03-04 | 2003-08-26 | Methods of treating mesothelioma with suberoylanilide hydroxamic acid |
US10/665,079 US20040127523A1 (en) | 2002-03-04 | 2003-09-16 | Methods of treating cancer with HDAC inhibitors |
PCT/US2004/027943 WO2005018578A2 (en) | 2003-08-26 | 2004-08-26 | Method of treating cancer with hdac inhibitors |
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NO20061348L NO20061348L (no) | 2006-05-23 |
NO328575B1 true NO328575B1 (no) | 2010-03-22 |
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NO20061348A NO328575B1 (no) | 2003-08-26 | 2006-03-24 | Anvendelse av suberoylanilidhydroksyaminsyre (SAHA) for fremstilling av et oralt medikament for behandling av mesoteliom |
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JP (2) | JP4338734B2 (zh) |
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CN (1) | CN102188415A (zh) |
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CA (1) | CA2535806C (zh) |
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DK (1) | DK1663194T3 (zh) |
EC (1) | ECSP066452A (zh) |
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HR (1) | HRP20060080A2 (zh) |
IL (1) | IL173846A0 (zh) |
MA (1) | MA28209A1 (zh) |
NO (1) | NO328575B1 (zh) |
NZ (2) | NZ560485A (zh) |
PL (2) | PL1663194T3 (zh) |
PT (1) | PT1663194E (zh) |
RU (1) | RU2356547C2 (zh) |
SI (1) | SI1663194T1 (zh) |
WO (1) | WO2005018578A2 (zh) |
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US6777217B1 (en) | 1996-03-26 | 2004-08-17 | President And Fellows Of Harvard College | Histone deacetylases, and uses related thereto |
US20030129724A1 (en) | 2000-03-03 | 2003-07-10 | Grozinger Christina M. | Class II human histone deacetylases, and uses related thereto |
US7244853B2 (en) | 2001-05-09 | 2007-07-17 | President And Fellows Of Harvard College | Dioxanes and uses thereof |
US20040132825A1 (en) * | 2002-03-04 | 2004-07-08 | Bacopoulos Nicholas G. | Methods of treating cancer with HDAC inhibitors |
US7456219B2 (en) * | 2002-03-04 | 2008-11-25 | Merck Hdac Research, Llc | Polymorphs of suberoylanilide hydroxamic acid |
BR0308250A (pt) * | 2002-03-04 | 2005-01-11 | Aton Pharma Inc | Métodos de indução de diferenciação terminal |
AU2003226408B2 (en) * | 2002-04-15 | 2007-06-14 | Sloan-Kettering Institute For Cancer Research | Combination therapy for the treatment of cancer |
CA2520611A1 (en) | 2003-04-01 | 2004-10-21 | Memorial Sloan-Kettering Cancer Center | Hydroxamic acid compounds and methods of use thereof |
US7901675B2 (en) * | 2004-10-13 | 2011-03-08 | U.S. Department Of Veterans Affairs | Method of using coenzyme Q10 to treat Huntington's disease |
US20060135612A1 (en) * | 2004-12-17 | 2006-06-22 | U.S. Department Of Veterans Affairs | Method of ameliorating or abrogating the effects of a neurodegenerative disorder, such as amyotrophic lateral sclerosis (ALS), by using a HDAC inhibiting agent |
AU2006210746B2 (en) | 2005-02-03 | 2012-04-26 | Topotarget Uk Limited | Combination therapies using HDAC inhibitors |
EP2491926B1 (en) | 2005-03-22 | 2018-05-09 | President and Fellows of Harvard College | Treatment of protein degradation disorders |
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