NO326135B1 - Stereoselektiv metode for fremstilling av nukleosider - Google Patents

Stereoselektiv metode for fremstilling av nukleosider Download PDF

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Publication number
NO326135B1
NO326135B1 NO20035556A NO20035556A NO326135B1 NO 326135 B1 NO326135 B1 NO 326135B1 NO 20035556 A NO20035556 A NO 20035556A NO 20035556 A NO20035556 A NO 20035556A NO 326135 B1 NO326135 B1 NO 326135B1
Authority
NO
Norway
Prior art keywords
alkyl
formula
optionally substituted
group
bromine
Prior art date
Application number
NO20035556A
Other languages
English (en)
Norwegian (no)
Other versions
NO20035556D0 (no
Inventor
Qing Yu
Original Assignee
Shire Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shire Canada Inc filed Critical Shire Canada Inc
Publication of NO20035556D0 publication Critical patent/NO20035556D0/no
Publication of NO326135B1 publication Critical patent/NO326135B1/no

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D411/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
NO20035556A 2001-06-15 2003-12-12 Stereoselektiv metode for fremstilling av nukleosider NO326135B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29807901P 2001-06-15 2001-06-15
PCT/CA2002/000899 WO2002102796A1 (en) 2001-06-15 2002-06-14 Stereoselective method for the preparation of nucleoside analogues

Publications (2)

Publication Number Publication Date
NO20035556D0 NO20035556D0 (no) 2003-12-12
NO326135B1 true NO326135B1 (no) 2008-10-06

Family

ID=23148927

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20035556A NO326135B1 (no) 2001-06-15 2003-12-12 Stereoselektiv metode for fremstilling av nukleosider

Country Status (29)

Country Link
US (2) US7109334B2 (zh)
EP (2) EP1406896B8 (zh)
JP (1) JP4542776B2 (zh)
KR (1) KR100832617B1 (zh)
CN (1) CN1297553C (zh)
AP (1) AP1559A (zh)
AT (2) ATE370945T1 (zh)
AU (2) AU2002344862C1 (zh)
BR (2) BR0210444A (zh)
CA (1) CA2449338C (zh)
CO (1) CO5550497A2 (zh)
CY (1) CY1107805T1 (zh)
DE (2) DE60222031T2 (zh)
DK (2) DK1632490T3 (zh)
EA (1) EA006372B1 (zh)
ES (2) ES2254695T3 (zh)
HK (1) HK1070652A1 (zh)
HR (1) HRP20031021B1 (zh)
IL (2) IL159139A0 (zh)
MX (1) MXPA03011627A (zh)
NO (1) NO326135B1 (zh)
NZ (1) NZ529906A (zh)
OA (1) OA12628A (zh)
PL (2) PL215267B1 (zh)
PT (1) PT1632490E (zh)
RS (1) RS50868B (zh)
SI (2) SI1632490T1 (zh)
WO (1) WO2002102796A1 (zh)
ZA (1) ZA200309307B (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7501514B1 (en) 2003-10-15 2009-03-10 Shire Biochem, Inc. Enantiomeric resolution of 2-substituted 4-substituted 1,3-oxathiolanes nucleosides
JP4653966B2 (ja) * 2004-04-19 2011-03-16 ダイセル化学工業株式会社 2−ベンゾイルオキシアセトアルデヒド誘導体の製造法
IN2015DN02599A (zh) * 2007-09-28 2015-09-18 Avexa Ltd
US20130165350A1 (en) * 2011-12-22 2013-06-27 Affymetrix, Inc. Surface linkers for array synthesis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR840001591A (ko) 1981-09-29 1984-05-07 구라바야시 이꾸시로 당케탈류의 제조방법
US5587480A (en) * 1990-11-13 1996-12-24 Biochem Pharma, Inc. Substituted 1,3-oxathiolanes and substituted 1,3-dithiolanes with antiviral properties
ES2091948T3 (es) * 1990-11-13 1996-11-16 Iaf Biochem Int 1,3-oxatiolanos sustituidos con propiedades antiviricas.
US5532349A (en) 1993-07-20 1996-07-02 Mitsui Toatsu Chemicals, Inc. Process for producing 1-(2'-deoxy-β-D-erythro-pentofuranosyl)-5-trifluoromethyluracil derivatives
EP1104415B1 (en) 1998-08-12 2004-11-10 Gilead Sciences, Inc. Method of manufacture of 1,3-oxathiolane nucleosides

Also Published As

Publication number Publication date
RS50868B (sr) 2010-08-31
ATE313542T1 (de) 2006-01-15
US7109334B2 (en) 2006-09-19
US20030135048A1 (en) 2003-07-17
AP1559A (en) 2006-01-24
IL159139A0 (en) 2004-06-01
HRP20031021A2 (en) 2004-06-30
HK1070652A1 (en) 2005-06-24
CY1107805T1 (el) 2013-06-19
DE60222031D1 (de) 2007-10-04
EP1632490A1 (en) 2006-03-08
US7230100B2 (en) 2007-06-12
DE60222031T2 (de) 2008-05-21
DK1406896T3 (da) 2006-05-08
PL366907A1 (en) 2005-02-07
YU97503A (sh) 2006-05-25
ATE370945T1 (de) 2007-09-15
SI1406896T1 (sl) 2006-04-30
DE60208202D1 (de) 2006-01-26
KR20040017233A (ko) 2004-02-26
CN1543463A (zh) 2004-11-03
AU2002344862B2 (en) 2008-05-01
IL159139A (en) 2010-04-15
HRP20031021B1 (en) 2007-09-30
SI1632490T1 (sl) 2008-02-29
AU2002344862C1 (en) 2009-02-19
CN1297553C (zh) 2007-01-31
KR100832617B1 (ko) 2008-05-27
EP1406896B8 (en) 2006-11-15
PL401835A1 (pl) 2013-02-18
DE60208202T2 (de) 2006-08-17
OA12628A (en) 2006-06-13
ES2254695T3 (es) 2006-06-16
AU2008203443B2 (en) 2011-06-16
ZA200309307B (en) 2005-02-23
DK1632490T3 (da) 2008-01-28
WO2002102796A8 (en) 2003-09-18
PL218777B1 (pl) 2015-01-30
CO5550497A2 (es) 2005-08-31
EP1406896A1 (en) 2004-04-14
EA200400042A1 (ru) 2004-06-24
EA006372B1 (ru) 2005-12-29
BR0210444A (pt) 2004-08-17
JP2004535428A (ja) 2004-11-25
MXPA03011627A (es) 2005-03-07
AU2008203443A1 (en) 2008-08-21
NZ529906A (en) 2006-03-31
ES2293445T3 (es) 2008-03-16
CA2449338A1 (en) 2002-12-27
WO2002102796A1 (en) 2002-12-27
BRPI0210444B1 (pt) 2017-06-20
US20060183899A1 (en) 2006-08-17
EP1632490B1 (en) 2007-08-22
NO20035556D0 (no) 2003-12-12
JP4542776B2 (ja) 2010-09-15
PT1632490E (pt) 2007-11-07
CA2449338C (en) 2012-02-07
PL215267B1 (pl) 2013-11-29
EP1406896B1 (en) 2005-12-21

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NO326135B1 (no) Stereoselektiv metode for fremstilling av nukleosider
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