NO324601B1 - Fremgangsmate for fremstilling av distamycinderivater samt mellomprodukt for anvendelse deri. - Google Patents

Fremgangsmate for fremstilling av distamycinderivater samt mellomprodukt for anvendelse deri. Download PDF

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Publication number
NO324601B1
NO324601B1 NO20032297A NO20032297A NO324601B1 NO 324601 B1 NO324601 B1 NO 324601B1 NO 20032297 A NO20032297 A NO 20032297A NO 20032297 A NO20032297 A NO 20032297A NO 324601 B1 NO324601 B1 NO 324601B1
Authority
NO
Norway
Prior art keywords
formula
compound
acid
carried out
reaction
Prior art date
Application number
NO20032297A
Other languages
English (en)
Norwegian (no)
Other versions
NO20032297L (no
NO20032297D0 (no
Inventor
Ilaria Candiani
Francesco Caldarelli
Lucio Ceriani
Original Assignee
Nerviano Medical Sciences Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nerviano Medical Sciences Srl filed Critical Nerviano Medical Sciences Srl
Publication of NO20032297L publication Critical patent/NO20032297L/no
Publication of NO20032297D0 publication Critical patent/NO20032297D0/no
Publication of NO324601B1 publication Critical patent/NO324601B1/no

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/42Nitro radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrrole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
NO20032297A 2000-11-28 2003-05-21 Fremgangsmate for fremstilling av distamycinderivater samt mellomprodukt for anvendelse deri. NO324601B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0029004.9A GB0029004D0 (en) 2000-11-28 2000-11-28 Process for preparing distamycin derivatives
PCT/EP2001/013050 WO2002044147A1 (en) 2000-11-28 2001-11-07 Process for preparing distamycin derivatives

Publications (3)

Publication Number Publication Date
NO20032297L NO20032297L (no) 2003-05-21
NO20032297D0 NO20032297D0 (no) 2003-05-21
NO324601B1 true NO324601B1 (no) 2007-11-26

Family

ID=9904031

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20032297A NO324601B1 (no) 2000-11-28 2003-05-21 Fremgangsmate for fremstilling av distamycinderivater samt mellomprodukt for anvendelse deri.

Country Status (31)

Country Link
US (1) US6906199B2 (ru)
EP (1) EP1347958B1 (ru)
JP (1) JP4574944B2 (ru)
KR (1) KR100847234B1 (ru)
CN (1) CN1190418C (ru)
AR (1) AR035073A1 (ru)
AT (1) ATE287395T1 (ru)
AU (2) AU2069602A (ru)
BR (1) BR0115351A (ru)
CA (1) CA2427177C (ru)
CZ (1) CZ303461B6 (ru)
DE (1) DE60108528T2 (ru)
EA (1) EA005399B1 (ru)
EE (1) EE05218B1 (ru)
ES (1) ES2236365T3 (ru)
GB (1) GB0029004D0 (ru)
HK (1) HK1060732A1 (ru)
HU (1) HU229670B1 (ru)
IL (2) IL155385A0 (ru)
MX (1) MXPA03004679A (ru)
MY (1) MY134563A (ru)
NO (1) NO324601B1 (ru)
NZ (1) NZ525230A (ru)
PE (1) PE20020551A1 (ru)
PL (1) PL205821B1 (ru)
PT (1) PT1347958E (ru)
SI (1) SI1347958T1 (ru)
SK (1) SK286610B6 (ru)
TW (1) TWI287002B (ru)
WO (1) WO2002044147A1 (ru)
ZA (1) ZA200302771B (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100842363B1 (ko) * 2007-04-05 2008-07-02 김춘동 튜브 짜개
CA2907045C (en) * 2013-03-15 2020-12-08 Merial Limited Antimicrobial polyamide compositions and mastitis treatment
JP2015080906A (ja) * 2013-10-23 2015-04-27 セイコーエプソン株式会社 液体収容容器、液体噴射装置
WO2023149487A1 (ja) * 2022-02-02 2023-08-10 国立大学法人千葉大学 ピロール・イミダゾールポリアミドの製造方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8612218D0 (en) 1986-05-20 1986-06-25 Erba Farmitalia Site specific alkylating agents
DE3768419D1 (de) 1986-10-07 1991-04-11 Boehringer Biochemia Srl Pharmazeutische zusammensetzungen mit antineoplastischer wirkung.
GB8906709D0 (en) 1989-03-23 1989-05-10 Creighton Andrew M Acryloyl substituted pyrrole derivatives
JP2919867B2 (ja) 1989-09-27 1999-07-19 千寿製薬株式会社 抗腫瘍剤
IT1272234B (it) * 1994-05-02 1997-06-16 Consiglio Nazionale Ricerche Derivati glutationici delle antracicline e procedimento per ottenerli.
GB9416005D0 (en) 1994-08-08 1994-09-28 Erba Carlo Spa Peptidic compounds analogous to distamycin a and process for their preparation
US5880097A (en) * 1996-01-04 1999-03-09 Terrapin Techologies, Inc. Tethered prodrugs
GB9610079D0 (en) 1996-05-14 1996-07-17 Pharmacia Spa Distamycin deriratives process for preparing them and their use as antitumor and antiviral agents
KR100469778B1 (ko) * 1996-05-14 2005-05-16 파머시아 앤 업잔 에스.피.에이. 디스타마이신유도체,이의제조방법,및항종양성및항바이러스성제제로서의이들의용도
GB9615692D0 (en) * 1996-07-25 1996-09-04 Pharmacia Spa Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
GB9623522D0 (en) 1996-11-11 1997-01-08 Pharmacia & Upjohn Spa Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents
GB9727524D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Synergistic antitumor composition containing a biologically active ureido compound
GB9806689D0 (en) 1998-03-27 1998-05-27 Pharmacia & Upjohn Spa Acryloyl derivatives analogous to distamycin,process for preparing them,and their use as antitumour and antiviral agents
GB9806692D0 (en) 1998-03-27 1998-05-27 Pharmacia & Upjohn Spa Benzoheterocyclic distamycin derivatives, process for preparing them and their use as antitumour agents
GB9816653D0 (en) 1998-07-30 1998-09-30 Pharmacia & Upjohn Spa Oxidised sulfurated distamycin derivatives process for preparing them and their use as antitumor agents
GB9816652D0 (en) 1998-07-30 1998-09-30 Pharmacia & Upjohn Spa Sulfurated distamycin derivatives process for preparing them and their use as antitumor agents

Also Published As

Publication number Publication date
EE05218B1 (et) 2009-10-15
CZ303461B6 (cs) 2012-09-26
US6906199B2 (en) 2005-06-14
ATE287395T1 (de) 2005-02-15
PL362179A1 (en) 2004-10-18
TWI287002B (en) 2007-09-21
NZ525230A (en) 2004-06-25
ZA200302771B (en) 2004-04-13
CN1476431A (zh) 2004-02-18
WO2002044147A1 (en) 2002-06-06
EE200300204A (et) 2003-08-15
EA005399B1 (ru) 2005-02-24
SI1347958T1 (ru) 2005-08-31
CZ20031132A3 (cs) 2003-08-13
AU2002220696B2 (en) 2006-11-30
JP4574944B2 (ja) 2010-11-04
HK1060732A1 (en) 2004-08-20
EP1347958B1 (en) 2005-01-19
PE20020551A1 (es) 2002-06-12
HU229670B1 (en) 2014-04-28
CA2427177A1 (en) 2002-06-06
NO20032297L (no) 2003-05-21
GB0029004D0 (en) 2001-01-10
PL205821B1 (pl) 2010-05-31
MXPA03004679A (es) 2003-09-05
SK286610B6 (sk) 2009-02-05
PT1347958E (pt) 2005-05-31
AR035073A1 (es) 2004-04-14
DE60108528T2 (de) 2006-03-23
EA200300617A1 (ru) 2003-10-30
DE60108528D1 (de) 2005-02-24
ES2236365T3 (es) 2005-07-16
IL155385A0 (en) 2003-11-23
SK8322003A3 (en) 2003-10-07
AU2069602A (en) 2002-06-11
HUP0302158A2 (hu) 2003-09-29
IL155385A (en) 2009-02-11
JP2004517830A (ja) 2004-06-17
BR0115351A (pt) 2003-08-26
US20040077550A1 (en) 2004-04-22
EP1347958A1 (en) 2003-10-01
KR20030066681A (ko) 2003-08-09
KR100847234B1 (ko) 2008-07-18
CA2427177C (en) 2010-01-19
CN1190418C (zh) 2005-02-23
NO20032297D0 (no) 2003-05-21
MY134563A (en) 2007-12-31

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