NO323642B1 - Trekloverpeptiddimer, fremgangsmate for fremstilling derav, farmasoytisk preparat som omfatter en slik, og anvendelse av en trekloverpeptiddimer til fremstilling av et medikament for profylakse eller behandling av mave- og tarmkanalsykdommer - Google Patents

Trekloverpeptiddimer, fremgangsmate for fremstilling derav, farmasoytisk preparat som omfatter en slik, og anvendelse av en trekloverpeptiddimer til fremstilling av et medikament for profylakse eller behandling av mave- og tarmkanalsykdommer Download PDF

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Publication number
NO323642B1
NO323642B1 NO19970844A NO970844A NO323642B1 NO 323642 B1 NO323642 B1 NO 323642B1 NO 19970844 A NO19970844 A NO 19970844A NO 970844 A NO970844 A NO 970844A NO 323642 B1 NO323642 B1 NO 323642B1
Authority
NO
Norway
Prior art keywords
trefoil
dimer
trefoil peptide
peptide
monomer
Prior art date
Application number
NO19970844A
Other languages
English (en)
Norwegian (no)
Other versions
NO970844L (no
NO970844D0 (no
Inventor
Lars Thim
Helle Fabricius Woeldike
Per Franklin Nielsen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO970844D0 publication Critical patent/NO970844D0/no
Publication of NO970844L publication Critical patent/NO970844L/no
Publication of NO323642B1 publication Critical patent/NO323642B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
NO19970844A 1994-08-26 1997-02-25 Trekloverpeptiddimer, fremgangsmate for fremstilling derav, farmasoytisk preparat som omfatter en slik, og anvendelse av en trekloverpeptiddimer til fremstilling av et medikament for profylakse eller behandling av mave- og tarmkanalsykdommer NO323642B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK98394 1994-08-26
PCT/DK1995/000343 WO1996006861A1 (en) 1994-08-26 1995-08-25 Trefoil peptide dimer

Publications (3)

Publication Number Publication Date
NO970844D0 NO970844D0 (no) 1997-02-25
NO970844L NO970844L (no) 1997-04-28
NO323642B1 true NO323642B1 (no) 2007-06-18

Family

ID=8099704

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19970844A NO323642B1 (no) 1994-08-26 1997-02-25 Trekloverpeptiddimer, fremgangsmate for fremstilling derav, farmasoytisk preparat som omfatter en slik, og anvendelse av en trekloverpeptiddimer til fremstilling av et medikament for profylakse eller behandling av mave- og tarmkanalsykdommer

Country Status (21)

Country Link
EP (2) EP0777687B1 (hu)
JP (3) JPH10504720A (hu)
KR (1) KR100255911B1 (hu)
CN (1) CN1070867C (hu)
AT (1) ATE329929T1 (hu)
AU (1) AU694796B2 (hu)
BR (1) BR9508773A (hu)
CA (1) CA2196876C (hu)
CZ (2) CZ289705B6 (hu)
DE (1) DE69535060T2 (hu)
DK (1) DK0777687T3 (hu)
ES (1) ES2267104T3 (hu)
FI (1) FI119989B (hu)
HU (1) HU226921B1 (hu)
MX (1) MX9701239A (hu)
NO (1) NO323642B1 (hu)
PL (1) PL184516B1 (hu)
PT (1) PT777687E (hu)
RU (1) RU2162857C2 (hu)
UA (1) UA68324C2 (hu)
WO (1) WO1996006861A1 (hu)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6063755A (en) 1991-02-14 2000-05-16 The General Hospital Corporation Intestinal trefoil proteins
US6221840B1 (en) * 1991-02-14 2001-04-24 The General Hospital Corporation Intestinal trefoil proteins
US6337195B1 (en) 1995-06-06 2002-01-08 Human Genome Sciences, Inc. Colon specific genes and proteins
US6525018B1 (en) 1999-05-17 2003-02-25 The General Hospital Corp. Treating eye disorders using intestinal trefoil proteins
US6426404B1 (en) 1997-08-25 2002-07-30 The General Hospital Corporation Receptor for intestinal trefoil factor
WO2001092528A2 (en) * 2000-05-26 2001-12-06 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating colon cancer
WO2002046226A2 (en) * 2000-12-08 2002-06-13 Novo Nordisk A/S Trefoil factor 2 (tff2) peptides with moiety attached to asn15
EP1842858A3 (en) * 2001-04-24 2008-04-02 The General Hospital Corporation Methods and compositions for treating oral and esophageal lesions
US7538082B2 (en) 2001-04-24 2009-05-26 The General Hospital Corporation Methods and compositions for treating oral and esophageal lesions
MXPA03009772A (es) * 2001-04-24 2004-02-23 Gen Hospital Corp Metodos y composiciones para tratar lesiones orales y del esofago.
JP2004534075A (ja) * 2001-06-14 2004-11-11 ノボ ノルディスク アクティーゼルスカブ Tffダイマーペプチドによる粘膜修復
WO2003068817A1 (en) * 2002-02-11 2003-08-21 Novo Nordisk A/S Management of mucosal viscosity by tff monomer peptides
WO2003082196A2 (en) * 2002-03-26 2003-10-09 The General Hospital Corporation Combination therapy using trefoil peptides
ATE550041T1 (de) 2004-01-21 2012-04-15 Novo Nordisk Healthcare Ag Transglutaminase-vermittelte konjugation von peptiden
EP2575864A1 (en) 2010-06-04 2013-04-10 Trifoilium ApS Trefoil factors (tff) for the treatment of chronic pulmonary diseases
CN102526702A (zh) * 2010-12-23 2012-07-04 中国医学科学院基础医学研究所 小肽tff3治疗代谢综合征的用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992014837A1 (en) * 1991-02-14 1992-09-03 The General Hospital Corporation Intestinal trefoil proteins

Also Published As

Publication number Publication date
FI970783A0 (fi) 1997-02-25
CA2196876C (en) 2007-04-17
ATE329929T1 (de) 2006-07-15
CN1156459A (zh) 1997-08-06
DK0777687T3 (da) 2006-10-16
AU694796B2 (en) 1998-07-30
KR100255911B1 (ko) 2000-05-01
NO970844L (no) 1997-04-28
HUT77917A (hu) 1998-10-28
FI970783A (fi) 1997-02-25
BR9508773A (pt) 1997-12-30
DE69535060D1 (de) 2006-07-27
CN1070867C (zh) 2001-09-12
CZ54897A3 (en) 1997-08-13
FI119989B (fi) 2009-05-29
UA68324C2 (en) 2004-08-16
HU226921B1 (en) 2010-03-01
CA2196876A1 (en) 1996-03-07
ES2267104T3 (es) 2007-03-01
EP0777687B1 (en) 2006-06-14
JP4156829B2 (ja) 2008-09-24
DE69535060T2 (de) 2006-12-28
NO970844D0 (no) 1997-02-25
MX9701239A (es) 1997-05-31
RU2162857C2 (ru) 2001-02-10
WO1996006861A1 (en) 1996-03-07
JP2002191385A (ja) 2002-07-09
CZ289864B6 (cs) 2002-04-17
PL318785A1 (en) 1997-07-07
PL184516B1 (pl) 2002-11-29
EP0777687A1 (en) 1997-06-11
JP2007161720A (ja) 2007-06-28
AU3341595A (en) 1996-03-22
PT777687E (pt) 2006-10-31
CZ289705B6 (cs) 2002-03-13
JPH10504720A (ja) 1998-05-12
EP1739091A1 (en) 2007-01-03

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