FI119989B - Apilapeptididimeeri, menetelmä sen valmistamiseksi ja tällaisen dimeerin sisältävä farmaseuttinen koostumus sekä sen käyttö - Google Patents

Apilapeptididimeeri, menetelmä sen valmistamiseksi ja tällaisen dimeerin sisältävä farmaseuttinen koostumus sekä sen käyttö Download PDF

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Publication number
FI119989B
FI119989B FI970783A FI970783A FI119989B FI 119989 B FI119989 B FI 119989B FI 970783 A FI970783 A FI 970783A FI 970783 A FI970783 A FI 970783A FI 119989 B FI119989 B FI 119989B
Authority
FI
Finland
Prior art keywords
clover
peptide
dimer
monomer
peptide dimer
Prior art date
Application number
FI970783A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI970783A0 (fi
FI970783A (fi
Inventor
Helle Fabricius Woeldike
Lars Thim
Per Franklin Nielsen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of FI970783A0 publication Critical patent/FI970783A0/fi
Publication of FI970783A publication Critical patent/FI970783A/fi
Application granted granted Critical
Publication of FI119989B publication Critical patent/FI119989B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
FI970783A 1994-08-26 1997-02-25 Apilapeptididimeeri, menetelmä sen valmistamiseksi ja tällaisen dimeerin sisältävä farmaseuttinen koostumus sekä sen käyttö FI119989B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK98394 1994-08-26
DK98394 1994-08-26
PCT/DK1995/000343 WO1996006861A1 (en) 1994-08-26 1995-08-25 Trefoil peptide dimer
DK9500343 1995-08-25

Publications (3)

Publication Number Publication Date
FI970783A0 FI970783A0 (fi) 1997-02-25
FI970783A FI970783A (fi) 1997-02-25
FI119989B true FI119989B (fi) 2009-05-29

Family

ID=8099704

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970783A FI119989B (fi) 1994-08-26 1997-02-25 Apilapeptididimeeri, menetelmä sen valmistamiseksi ja tällaisen dimeerin sisältävä farmaseuttinen koostumus sekä sen käyttö

Country Status (21)

Country Link
EP (2) EP0777687B1 (hu)
JP (3) JPH10504720A (hu)
KR (1) KR100255911B1 (hu)
CN (1) CN1070867C (hu)
AT (1) ATE329929T1 (hu)
AU (1) AU694796B2 (hu)
BR (1) BR9508773A (hu)
CA (1) CA2196876C (hu)
CZ (2) CZ289705B6 (hu)
DE (1) DE69535060T2 (hu)
DK (1) DK0777687T3 (hu)
ES (1) ES2267104T3 (hu)
FI (1) FI119989B (hu)
HU (1) HU226921B1 (hu)
MX (1) MX9701239A (hu)
NO (1) NO323642B1 (hu)
PL (1) PL184516B1 (hu)
PT (1) PT777687E (hu)
RU (1) RU2162857C2 (hu)
UA (1) UA68324C2 (hu)
WO (1) WO1996006861A1 (hu)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6063755A (en) 1991-02-14 2000-05-16 The General Hospital Corporation Intestinal trefoil proteins
US6221840B1 (en) * 1991-02-14 2001-04-24 The General Hospital Corporation Intestinal trefoil proteins
US6337195B1 (en) 1995-06-06 2002-01-08 Human Genome Sciences, Inc. Colon specific genes and proteins
US6525018B1 (en) 1999-05-17 2003-02-25 The General Hospital Corp. Treating eye disorders using intestinal trefoil proteins
US6426404B1 (en) 1997-08-25 2002-07-30 The General Hospital Corporation Receptor for intestinal trefoil factor
WO2001092528A2 (en) * 2000-05-26 2001-12-06 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating colon cancer
WO2002046226A2 (en) * 2000-12-08 2002-06-13 Novo Nordisk A/S Trefoil factor 2 (tff2) peptides with moiety attached to asn15
EP1842858A3 (en) * 2001-04-24 2008-04-02 The General Hospital Corporation Methods and compositions for treating oral and esophageal lesions
US7538082B2 (en) 2001-04-24 2009-05-26 The General Hospital Corporation Methods and compositions for treating oral and esophageal lesions
MXPA03009772A (es) * 2001-04-24 2004-02-23 Gen Hospital Corp Metodos y composiciones para tratar lesiones orales y del esofago.
JP2004534075A (ja) * 2001-06-14 2004-11-11 ノボ　ノルディスク　アクティーゼルスカブ Ｔｆｆダイマーペプチドによる粘膜修復
WO2003068817A1 (en) * 2002-02-11 2003-08-21 Novo Nordisk A/S Management of mucosal viscosity by tff monomer peptides
WO2003082196A2 (en) * 2002-03-26 2003-10-09 The General Hospital Corporation Combination therapy using trefoil peptides
ATE550041T1 (de) 2004-01-21 2012-04-15 Novo Nordisk Healthcare Ag Transglutaminase-vermittelte konjugation von peptiden
EP2575864A1 (en) 2010-06-04 2013-04-10 Trifoilium ApS Trefoil factors (tff) for the treatment of chronic pulmonary diseases
CN102526702A (zh) * 2010-12-23 2012-07-04 中国医学科学院基础医学研究所 小肽tff3治疗代谢综合征的用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992014837A1 (en) * 1991-02-14 1992-09-03 The General Hospital Corporation Intestinal trefoil proteins

Also Published As

Publication number Publication date
FI970783A0 (fi) 1997-02-25
CA2196876C (en) 2007-04-17
ATE329929T1 (de) 2006-07-15
CN1156459A (zh) 1997-08-06
DK0777687T3 (da) 2006-10-16
AU694796B2 (en) 1998-07-30
KR100255911B1 (ko) 2000-05-01
NO970844L (no) 1997-04-28
HUT77917A (hu) 1998-10-28
FI970783A (fi) 1997-02-25
BR9508773A (pt) 1997-12-30
DE69535060D1 (de) 2006-07-27
CN1070867C (zh) 2001-09-12
CZ54897A3 (en) 1997-08-13
UA68324C2 (en) 2004-08-16
HU226921B1 (en) 2010-03-01
CA2196876A1 (en) 1996-03-07
ES2267104T3 (es) 2007-03-01
EP0777687B1 (en) 2006-06-14
JP4156829B2 (ja) 2008-09-24
DE69535060T2 (de) 2006-12-28
NO970844D0 (no) 1997-02-25
NO323642B1 (no) 2007-06-18
MX9701239A (es) 1997-05-31
RU2162857C2 (ru) 2001-02-10
WO1996006861A1 (en) 1996-03-07
JP2002191385A (ja) 2002-07-09
CZ289864B6 (cs) 2002-04-17
PL318785A1 (en) 1997-07-07
PL184516B1 (pl) 2002-11-29
EP0777687A1 (en) 1997-06-11
JP2007161720A (ja) 2007-06-28
AU3341595A (en) 1996-03-22
PT777687E (pt) 2006-10-31
CZ289705B6 (cs) 2002-03-13
JPH10504720A (ja) 1998-05-12
EP1739091A1 (en) 2007-01-03

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