NO322962B1 - Anvendelse av et rekombinant protein for fremstilling av et preparat for behandling av tilstander relatert til eksokrin bukspyttkjertelinsuffisiens - Google Patents

Anvendelse av et rekombinant protein for fremstilling av et preparat for behandling av tilstander relatert til eksokrin bukspyttkjertelinsuffisiens Download PDF

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Publication number
NO322962B1
NO322962B1 NO19924528A NO924528A NO322962B1 NO 322962 B1 NO322962 B1 NO 322962B1 NO 19924528 A NO19924528 A NO 19924528A NO 924528 A NO924528 A NO 924528A NO 322962 B1 NO322962 B1 NO 322962B1
Authority
NO
Norway
Prior art keywords
bssl
protein
amino acid
treatment
sequence
Prior art date
Application number
NO19924528A
Other languages
English (en)
Norwegian (no)
Other versions
NO924528D0 (no
NO924528L (no
Inventor
Gunnar Bjursell
Jeanette Nilsson
Lars Blackberg
Olle Hernell
Peter Carlsson
Sven Enerback
Thomas Olivecrona
Original Assignee
Arexis Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arexis Ab filed Critical Arexis Ab
Publication of NO924528D0 publication Critical patent/NO924528D0/no
Publication of NO924528L publication Critical patent/NO924528L/no
Publication of NO322962B1 publication Critical patent/NO322962B1/no

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • C12N9/20Triglyceride splitting, e.g. by means of lipase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/442Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/596Mixtures of surface active compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO19924528A 1990-06-01 1992-11-24 Anvendelse av et rekombinant protein for fremstilling av et preparat for behandling av tilstander relatert til eksokrin bukspyttkjertelinsuffisiens NO322962B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9001985A SE9001985D0 (sv) 1990-06-01 1990-06-01 New chemical products
PCT/SE1991/000381 WO1991018923A1 (en) 1990-06-01 1991-05-30 Derivatives of human bile-salt stimulated lipase, and pharmaceutical compositions containing them

Publications (3)

Publication Number Publication Date
NO924528D0 NO924528D0 (no) 1992-11-24
NO924528L NO924528L (no) 1992-11-24
NO322962B1 true NO322962B1 (no) 2006-12-18

Family

ID=20379662

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19924528A NO322962B1 (no) 1990-06-01 1992-11-24 Anvendelse av et rekombinant protein for fremstilling av et preparat for behandling av tilstander relatert til eksokrin bukspyttkjertelinsuffisiens

Country Status (44)

Country Link
EP (1) EP0535048B1 (es)
JP (1) JPH05507201A (es)
KR (1) KR100212411B1 (es)
CN (2) CN1075113C (es)
AP (1) AP207A (es)
AT (1) ATE151077T1 (es)
AU (1) AU651979B2 (es)
BG (1) BG61165B1 (es)
CA (1) CA2083396C (es)
CZ (1) CZ287470B6 (es)
DE (1) DE69125489T2 (es)
DK (1) DK0535048T3 (es)
DZ (1) DZ1503A1 (es)
EG (1) EG19937A (es)
ES (1) ES2099159T3 (es)
FI (1) FI114639B (es)
GR (1) GR3023618T3 (es)
HK (1) HK62497A (es)
HR (1) HRP920771B1 (es)
HU (1) HU215258B (es)
IE (1) IE911844A1 (es)
IL (1) IL98273A (es)
IS (1) IS1751B (es)
JO (1) JO1694B1 (es)
LT (1) LT4020B (es)
LV (1) LV10292B (es)
MA (1) MA22166A1 (es)
MY (1) MY111245A (es)
NO (1) NO322962B1 (es)
NZ (1) NZ238223A (es)
PH (1) PH30761A (es)
PL (1) PL166534B1 (es)
PT (1) PT97836B (es)
RO (1) RO114793B1 (es)
RU (1) RU2140983C1 (es)
SE (1) SE9001985D0 (es)
SG (1) SG48078A1 (es)
SK (1) SK281089B6 (es)
TN (1) TNSN91041A1 (es)
TW (1) TW221712B (es)
UA (1) UA39165C2 (es)
WO (1) WO1991018923A1 (es)
YU (1) YU49138B (es)
ZA (1) ZA913778B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP930935A2 (en) * 1992-06-11 1994-12-31 Astra Ab New dna sequences
SE9300686D0 (sv) 1993-03-01 1993-03-01 Astra Ab Novel polypeptides
IS4130A (is) * 1993-03-01 1994-09-02 Ab Astra Ný fjölpeptíð
FR2754827B1 (fr) * 1996-10-17 1998-12-24 Biocem Lipases pancreatiques et/ou colipases recombinantes et polypeptides dervies produits par les plantes, leurs procedes d'obtention et leurs utilisations
JP2000026311A (ja) * 1998-07-02 2000-01-25 Amano Pharmaceut Co Ltd 胃排出能亢進剤組成物
US20090226904A1 (en) * 2005-12-01 2009-09-10 University Of Bergen Diagnosis and treatment of exocrine pancreatic dysfunction and diabetes
SI2561069T1 (sl) 2010-04-23 2017-07-31 Alexion Pharmaceuticals, Inc. Encim za bolezen lizosomskega shranjevanja
KR20150038636A (ko) 2010-09-09 2015-04-08 시나게바 바이오파르마, 코포레이션 환자에서 리소좀 산 리파제 결핍증의 치료를 위한 리소좀 산 리파제의 용도
RU2013123053A (ru) 2010-10-21 2014-11-27 Сведиш Орфан Биовитрум Аб (Пабл) Способ увеличения скорости роста новорожденных детей
CA2812852A1 (en) 2010-10-21 2012-04-26 Swedish Orphan Biovitrum Ab (Publ) Method to increase the absorption of unsaturated fatty acids by human infants
BR112019025973A2 (pt) * 2017-06-19 2020-07-07 Swedish Orphan Biovitrum Ab (Publ) proteína de fusão com polipeptídeo de extensão de meia-vida
EP4022049A4 (en) 2019-08-30 2023-11-01 Codexis, Inc. MODIFIED LIPASE VARIANTS

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0131418A1 (en) * 1983-07-01 1985-01-16 Celltech Limited Proteins, pharmaceutical compositons, genes, vectors, host organisms and processes for their production

Also Published As

Publication number Publication date
BG61165B1 (bg) 1997-01-31
GR3023618T3 (en) 1997-08-29
AU651979B2 (en) 1994-08-11
ZA913778B (en) 1992-02-26
HU9203774D0 (en) 1993-03-29
CN1326782A (zh) 2001-12-19
IL98273A (en) 2005-11-20
HU215258B (hu) 1998-11-30
IS3710A7 (is) 1991-12-02
HK62497A (en) 1997-05-16
CZ164491A3 (cs) 1999-07-14
YU95191A (sh) 1994-06-10
SE9001985D0 (sv) 1990-06-01
IL98273A0 (en) 1992-06-21
PH30761A (en) 1997-10-17
SK281089B6 (sk) 2000-11-07
JO1694B1 (en) 1992-08-09
JPH05507201A (ja) 1993-10-21
PT97836A (pt) 1992-02-28
ES2099159T3 (es) 1997-05-16
SG48078A1 (en) 1998-04-17
WO1991018923A1 (en) 1991-12-12
TW221712B (es) 1994-03-11
EP0535048B1 (en) 1997-04-02
EG19937A (en) 2000-12-31
IE911844A1 (en) 1991-12-04
LTIP1736A (en) 1995-08-25
KR100212411B1 (en) 1999-08-02
FI114639B (fi) 2004-11-30
UA39165C2 (uk) 2001-06-15
LT4020B (en) 1996-08-26
BG97123A (bg) 1993-12-24
FI925453A0 (fi) 1992-11-30
CA2083396A1 (en) 1991-12-02
MY111245A (en) 1999-10-30
YU49138B (sh) 2004-03-12
HRP920771B1 (en) 1999-10-31
IS1751B (is) 2000-07-21
MA22166A1 (fr) 1991-12-31
CN1064313A (zh) 1992-09-09
LV10292A (lv) 1994-10-20
TNSN91041A1 (fr) 1992-10-25
NO924528D0 (no) 1992-11-24
AP9100270A0 (en) 1991-07-31
FI925453A (fi) 1992-11-30
NO924528L (no) 1992-11-24
HRP920771A2 (en) 1997-04-30
DZ1503A1 (fr) 2004-09-13
RU2140983C1 (ru) 1999-11-10
PL166534B1 (pl) 1995-05-31
ATE151077T1 (de) 1997-04-15
RO114793B1 (ro) 1999-07-30
CN1075113C (zh) 2001-11-21
CA2083396C (en) 2006-09-19
HUT63184A (en) 1993-07-28
CZ287470B6 (cs) 2000-12-13
EP0535048A1 (en) 1993-04-07
SK164491A3 (en) 1995-07-11
AU7964591A (en) 1991-12-31
PT97836B (pt) 1998-11-30
LV10292B (en) 1995-08-20
DE69125489T2 (de) 1997-08-14
AP207A (en) 1992-08-18
DE69125489D1 (de) 1997-05-07
NZ238223A (en) 1993-05-26
DK0535048T3 (da) 1997-09-29

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