NO319383B1 - FLT4-reseptor tyrosinkinase og dens anvendelse ved diagnose og terapi - Google Patents
FLT4-reseptor tyrosinkinase og dens anvendelse ved diagnose og terapi Download PDFInfo
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- NO319383B1 NO319383B1 NO19965231A NO965231A NO319383B1 NO 319383 B1 NO319383 B1 NO 319383B1 NO 19965231 A NO19965231 A NO 19965231A NO 965231 A NO965231 A NO 965231A NO 319383 B1 NO319383 B1 NO 319383B1
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- flt4
- lymphatic
- flt
- tissue
- vessels
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- 239000000758 substrate Substances 0.000 description 1
- 229910052713 technetium Inorganic materials 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 210000002978 thoracic duct Anatomy 0.000 description 1
- 229960004072 thrombin Drugs 0.000 description 1
- 210000001541 thymus gland Anatomy 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 210000003556 vascular endothelial cell Anatomy 0.000 description 1
- 239000013598 vector Substances 0.000 description 1
- 210000001631 vena cava inferior Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Zoology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25775494A | 1994-06-09 | 1994-06-09 | |
| PCT/FI1995/000337 WO1995033772A1 (en) | 1994-06-09 | 1995-06-09 | Flt4 receptor tyrosine kinase and its use in diagnosis and therapy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO965231L NO965231L (no) | 1996-12-06 |
| NO965231D0 NO965231D0 (no) | 1996-12-06 |
| NO319383B1 true NO319383B1 (no) | 2005-07-25 |
Family
ID=22977612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19965231A NO319383B1 (no) | 1994-06-09 | 1996-12-06 | FLT4-reseptor tyrosinkinase og dens anvendelse ved diagnose og terapi |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0807124B1 (es) |
| JP (4) | JP3723210B2 (es) |
| AT (1) | ATE326484T1 (es) |
| AU (1) | AU694524B2 (es) |
| CA (1) | CA2192235C (es) |
| DE (1) | DE69534996T2 (es) |
| DK (1) | DK0807124T3 (es) |
| ES (1) | ES2263152T3 (es) |
| FI (1) | FI964862A (es) |
| MX (1) | MX9606218A (es) |
| NO (1) | NO319383B1 (es) |
| NZ (1) | NZ288235A (es) |
| PT (1) | PT807124E (es) |
| WO (1) | WO1995033772A1 (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6824777B1 (en) | 1992-10-09 | 2004-11-30 | Licentia Ltd. | Flt4 (VEGFR-3) as a target for tumor imaging and anti-tumor therapy |
| US6107046A (en) * | 1992-10-09 | 2000-08-22 | Orion Corporation | Antibodies to Flt4, a receptor tyrosine kinase and uses thereof |
| US6130071A (en) * | 1997-02-05 | 2000-10-10 | Helsinki University Licensing, Ltd. | Vascular endothelial growth factor C (VEGF-C) ΔCys156 protein and gene, and uses thereof |
| US6645933B1 (en) * | 1995-08-01 | 2003-11-11 | Helsinki University Licensing Ltd. Oy | Receptor ligand VEGF-C |
| WO2002060950A2 (en) | 1994-11-14 | 2002-08-08 | Ludwig Institute For Cancer Research | Flt4(vegfr-3) as a target for tumor imaging and anti-tumor therapy |
| US6245530B1 (en) | 1995-08-01 | 2001-06-12 | Ludwig Institute For Cancer Research | Receptor ligand |
| US6221839B1 (en) | 1994-11-14 | 2001-04-24 | Helsinki University Licensing Ltd. Oy | FIt4 ligand and methods of use |
| US6403088B1 (en) | 1995-08-01 | 2002-06-11 | Helsinki University Licensing, Ltd. | Antibodies reactive with VEGF-C, a ligand for the Flt4 receptor tyrosine kinase (VEGFR-3) |
| US6818220B1 (en) | 1994-11-14 | 2004-11-16 | Licentia Ltd. | Vascular endothelial growth factor C (VEGF-C) protein and gene mutants thereof, and uses thereof |
| US7423125B2 (en) | 1995-08-01 | 2008-09-09 | Vegenics Limited | Antibodies to VEGF-C |
| US6361946B1 (en) | 1997-02-05 | 2002-03-26 | Licentia Ltd | Vascular endothelial growth factor C (VEGF-C) protein and gene, mutants thereof, and uses thereof |
| EP0848755B2 (en) | 1995-09-08 | 2011-02-09 | Genentech, Inc. | Vegf-related protein |
| US6100071A (en) | 1996-05-07 | 2000-08-08 | Genentech, Inc. | Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production |
| US7125714B2 (en) | 1997-02-05 | 2006-10-24 | Licentia Ltd. | Progenitor cell materials and methods |
| FR2783325A1 (fr) * | 1998-09-11 | 2000-03-17 | Inst Nat Sante Rech Med | Moyens pour le controle de la regulation negative d'une activation transmise par un rtk |
| ATE489108T1 (de) * | 1998-10-09 | 2010-12-15 | Vegenics Ltd | Flt4 (vegfr-3) als ziel für tumornachweis (imaging) und antitumortherapie |
| WO2000062063A1 (en) * | 1999-04-13 | 2000-10-19 | Northwest Biotherapeutics, Inc. | Methods for the diagnosis and treatment of metastatic prostate tumors |
| EP1553414A1 (en) * | 1999-04-13 | 2005-07-13 | Medarex, Inc. | Methods for the diagnosis and treatment of metastatic prostate tumors |
| US6927203B1 (en) | 1999-08-17 | 2005-08-09 | Purdue Research Foundation | Treatment of metastatic disease |
| US6599717B1 (en) * | 1999-10-01 | 2003-07-29 | Exelixis, Inc. | Invertebrate vascular endothelial growth factor receptor |
| EP2025686A4 (en) * | 2006-05-29 | 2009-12-23 | Consejo Superior Investigacion | ANTI-CHOLINE KINASE ALPHA MONOCLONAL ANTIBODIES AND THEIR APPLICATION IN CANCER DIAGNOSTIC ANALYSIS, ANALYSIS AND DRUG PREPARATION TECHNIQUES |
| WO2008093246A2 (en) | 2007-02-02 | 2008-08-07 | Vegenics Limited | Vegf receptor antagonist for treating organ transplant alloimmunity and arteriosclerosis |
| AU2014218318B2 (en) | 2013-02-18 | 2018-02-15 | Vegenics Pty Limited | Ligand binding molecules and uses thereof |
| EP2994758B1 (en) | 2013-05-08 | 2017-12-20 | Opthea Limited | Biomarkers for age-related macular degeneration (amd) |
| CN114262683B (zh) * | 2022-03-01 | 2022-06-17 | 中国科学院动物研究所 | 一种表达vegfr3 d2多肽的细菌制剂及其构建方法和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR940703857A (ko) * | 1992-01-09 | 1994-12-12 | 티모 에스코 | 타이, 새로운 내피 세포 수용체 티로신 키나제(tie, a novel endothelial cell receptor tyrosine kinase) |
| DK0666868T4 (da) * | 1992-10-28 | 2006-09-18 | Genentech Inc | Anvendelse af anti-VEGF-antistoffer til behandling af cancer |
-
1995
- 1995-06-09 EP EP95922533A patent/EP0807124B1/en not_active Expired - Lifetime
- 1995-06-09 CA CA2192235A patent/CA2192235C/en not_active Expired - Lifetime
- 1995-06-09 WO PCT/FI1995/000337 patent/WO1995033772A1/en active IP Right Grant
- 1995-06-09 AU AU27388/95A patent/AU694524B2/en not_active Expired
- 1995-06-09 AT AT95922533T patent/ATE326484T1/de not_active IP Right Cessation
- 1995-06-09 DK DK95922533T patent/DK0807124T3/da active
- 1995-06-09 ES ES95922533T patent/ES2263152T3/es not_active Expired - Lifetime
- 1995-06-09 JP JP50041096A patent/JP3723210B2/ja not_active Expired - Fee Related
- 1995-06-09 MX MX9606218A patent/MX9606218A/es unknown
- 1995-06-09 NZ NZ288235A patent/NZ288235A/xx unknown
- 1995-06-09 DE DE69534996T patent/DE69534996T2/de not_active Expired - Lifetime
- 1995-06-09 PT PT95922533T patent/PT807124E/pt unknown
-
1996
- 1996-12-04 FI FI964862A patent/FI964862A/fi unknown
- 1996-12-06 NO NO19965231A patent/NO319383B1/no unknown
-
2005
- 2005-01-06 JP JP2005001867A patent/JP2005139199A/ja active Pending
-
2009
- 2009-02-04 JP JP2009023515A patent/JP2009102415A/ja active Pending
-
2012
- 2012-06-20 JP JP2012138421A patent/JP2012193191A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DK0807124T3 (da) | 2006-08-28 |
| FI964862A0 (fi) | 1996-12-04 |
| WO1995033772A1 (en) | 1995-12-14 |
| CA2192235A1 (en) | 1995-12-14 |
| NO965231L (no) | 1996-12-06 |
| ES2263152T3 (es) | 2006-12-01 |
| ATE326484T1 (de) | 2006-06-15 |
| NO965231D0 (no) | 1996-12-06 |
| EP0807124B1 (en) | 2006-05-17 |
| JPH10500858A (ja) | 1998-01-27 |
| MX9606218A (es) | 1998-02-28 |
| DE69534996D1 (de) | 2006-06-22 |
| JP2009102415A (ja) | 2009-05-14 |
| PT807124E (pt) | 2006-08-31 |
| FI964862A (fi) | 1997-02-10 |
| JP2012193191A (ja) | 2012-10-11 |
| JP2005139199A (ja) | 2005-06-02 |
| DE69534996T2 (de) | 2007-05-10 |
| AU694524B2 (en) | 1998-07-23 |
| JP3723210B2 (ja) | 2005-12-07 |
| NZ288235A (en) | 1999-05-28 |
| AU2738895A (en) | 1996-01-04 |
| CA2192235C (en) | 2011-02-15 |
| EP0807124A1 (en) | 1997-11-19 |
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