NO318352B1 - Triazolderivater med antifungal aktivitet, farmasoytiske preparater som omfatter slike forbindelser, samt anvendelse av forbindelsene ved fremstilling av medikamenter - Google Patents

Info

Publication number

NO318352B1

NO318352B1 NO20004511A NO20004511A NO318352B1 NO 318352 B1 NO318352 B1 NO 318352B1 NO 20004511 A NO20004511 A NO 20004511A NO 20004511 A NO20004511 A NO 20004511A NO 318352 B1 NO318352 B1 NO 318352B1

Authority

NO

Norway

Prior art keywords

doublet

compound

formula

doublets

group

Prior art date

1999-09-09

Links

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• 238000004519 manufacturing process Methods 0.000 title description 3
• 229940042055 systemic antimycotics triazole derivative Drugs 0.000 title description 3
• 239000008194 pharmaceutical composition Substances 0.000 title 1
• 150000003839 salts Chemical class 0.000 claims abstract description 65
• 150000002148 esters Chemical class 0.000 claims abstract description 52
• 125000001424 substituent group Chemical group 0.000 claims abstract description 24
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract description 13
• 125000005843 halogen group Chemical group 0.000 claims abstract description 12
• 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims abstract description 6
• 238000000034 method Methods 0.000 claims description 50
• XSRKBFUVSRRJDX-GGZJQHSXSA-N chembl475786 Chemical group C(/[C@H]1OC[C@@H](CO1)S[C@H](C)[C@](O)(CN1N=CN=C1)C=1C(=CC(F)=CC=1)F)=C\C=C\C1=CC=C(C#N)C=C1F XSRKBFUVSRRJDX-GGZJQHSXSA-N 0.000 claims description 18
• 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 10
• 241001465754 Metazoa Species 0.000 claims description 8
• 239000000843 powder Substances 0.000 claims description 8
• RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 7
• 229910052802 copper Inorganic materials 0.000 claims description 7
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• 125000004215 2,4-difluorophenyl group Chemical group [H]C1=C([H])C(*)=C(F)C([H])=C1F 0.000 claims description 6
• 238000002360 preparation method Methods 0.000 claims description 6
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