NO317770B1 - Anvendelse av fankinon for behandling av Alzheimers sykdom - Google Patents
Anvendelse av fankinon for behandling av Alzheimers sykdom Download PDFInfo
- Publication number
- NO317770B1 NO317770B1 NO20000771A NO20000771A NO317770B1 NO 317770 B1 NO317770 B1 NO 317770B1 NO 20000771 A NO20000771 A NO 20000771A NO 20000771 A NO20000771 A NO 20000771A NO 317770 B1 NO317770 B1 NO 317770B1
- Authority
- NO
- Norway
- Prior art keywords
- clioquinol
- pharmaceutical composition
- vitamin
- fanquinone
- disease
- Prior art date
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- 238000011282 treatment Methods 0.000 title claims abstract description 20
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR97100330 | 1997-08-21 | ||
| GR97100507 | 1997-12-31 | ||
| PCT/IB1998/001095 WO1999009981A1 (en) | 1997-08-21 | 1998-07-17 | Use of phanquinone for the treatment of alzheimer's disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20000771D0 NO20000771D0 (no) | 2000-02-16 |
| NO20000771L NO20000771L (no) | 2000-04-25 |
| NO317770B1 true NO317770B1 (no) | 2004-12-13 |
Family
ID=26316681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20000771A NO317770B1 (no) | 1997-08-21 | 2000-02-16 | Anvendelse av fankinon for behandling av Alzheimers sykdom |
Country Status (24)
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|---|---|
| US (2) | US6670369B1 (cs) |
| EP (1) | EP1007040B1 (cs) |
| JP (1) | JP2001513558A (cs) |
| CN (1) | CN1145482C (cs) |
| AT (1) | ATE217191T1 (cs) |
| AU (1) | AU741782B2 (cs) |
| BG (1) | BG64300B1 (cs) |
| BR (1) | BR9814945A (cs) |
| CA (1) | CA2301706C (cs) |
| CZ (1) | CZ299739B6 (cs) |
| DE (1) | DE69805305T2 (cs) |
| DK (1) | DK1007040T3 (cs) |
| EA (1) | EA002526B1 (cs) |
| ES (1) | ES2177024T3 (cs) |
| HU (1) | HUP0004331A3 (cs) |
| IL (1) | IL134263A (cs) |
| IS (1) | IS1910B (cs) |
| NO (1) | NO317770B1 (cs) |
| NZ (1) | NZ502565A (cs) |
| PL (1) | PL191208B1 (cs) |
| PT (1) | PT1007040E (cs) |
| SK (1) | SK284708B6 (cs) |
| TR (1) | TR200000455T2 (cs) |
| WO (1) | WO1999009981A1 (cs) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7045531B1 (en) | 1997-03-11 | 2006-05-16 | The General Hospital Corporation | Composition comprising a metal chelator and a method of treating amyloidosis by administering the metal chelator |
| US5994323A (en) * | 1997-12-31 | 1999-11-30 | P.N. Gerolymatos S.A. | Pharmaceutical compositions comprising clioquinol in combination with vitamin B12 and therapeutic and prophylactic uses thereof |
| US6323218B1 (en) * | 1998-03-11 | 2001-11-27 | The General Hospital Corporation | Agents for use in the treatment of Alzheimer's disease |
| US6638711B1 (en) | 1999-04-29 | 2003-10-28 | The General Hospital Corporation | Methods for identifying an agent that inhibits oxygen-dependent hydrogen peroxide formation activity but does not inhibit superoxide-dependent hydrogen peroxide formation |
| WO2000040244A1 (en) * | 1999-01-07 | 2000-07-13 | P.N. Gerolymatos S.A. | Use of phanquinone for the treatment or prevention of memory impairment |
| WO2001082912A2 (en) * | 2000-04-28 | 2001-11-08 | Gerolymatos P N Sa | TREATMENT OF PATHOLOGICAL CONDITIONS INFLUENCED BY THE ACTION OF MATRIX METALLOPROTEINASES (MMPs) USING PHANQUINONE |
| AU2001250571A1 (en) * | 2000-04-28 | 2001-11-12 | P.N. Gerolymatos S.A. | Treatment of pathological conditions influenced by the action of matrix metalloproteinases (mmps) using clioquinol |
| CA2452346A1 (en) | 2000-08-18 | 2002-02-28 | The General Hospital Corporation | Method for the identification of agents that inhibit or promote cataracts and uses thereof |
| FR2818551B1 (fr) * | 2000-12-22 | 2007-06-01 | Claude Marc Pierre Hannoun | Utilisation de chelateurs pour le traitement des maladies a prions |
| AU2002950217A0 (en) * | 2002-07-16 | 2002-09-12 | Prana Biotechnology Limited | 8- Hydroxy Quinoline Derivatives |
| EP1602286B1 (en) * | 2003-03-11 | 2009-10-28 | Kaneka Corporation | Oil-in-water type emulsion containing coenzyme q10 and process for producing the same |
| US20080207673A1 (en) * | 2005-05-04 | 2008-08-28 | Michel Xilinas | Method for Treating Cancer, Coronary, Inflammatory and Macular Disease, Combining the Modulation of Zinc-and/or Copper Dependent Proteins |
| US10478454B2 (en) * | 2014-04-29 | 2019-11-19 | Affiris Ag | Treatment of Alzheimer's disease (AD) with aluminum oxyhydroxide |
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| DE1617417A1 (de) * | 1966-12-08 | 1971-03-25 | Ciba Geigy | Pharmazeutisches Praeparat |
| DE1804736A1 (de) | 1967-11-02 | 1969-06-26 | Ciba Geigy | Pharmazeutisches Praeparat |
| IL40311A (en) | 1972-09-06 | 1973-04-30 | Pharmaplantex Ltd | Pharmaceutical preparation for the treatment of gastro-intestinal troubles containing phanquone and furazolidone |
| GB1472257A (en) * | 1973-09-10 | 1977-05-04 | Christiaens Sa A | Derivative of 4-hydroxy-5-azacoumarin |
| US5719197A (en) | 1988-03-04 | 1998-02-17 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| US5656286A (en) | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| US4981844A (en) * | 1988-10-04 | 1991-01-01 | University Of Cincinnati | Method to improve immune response and resistance to infection following surgery by diet composition |
| US5091391A (en) * | 1990-08-16 | 1992-02-25 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Method of resisting neurodegenerative disorders |
| US6165500A (en) | 1990-08-24 | 2000-12-26 | Idea Ag | Preparation for the application of agents in mini-droplets |
| AP387A (en) * | 1991-09-13 | 1995-07-31 | Siegbert Heinrich Bissbort | Therapeutical uses of L-methionine and compositions thereof. |
| DE69227380T3 (de) | 1991-11-12 | 2007-01-11 | Prana Biotechnology Ltd., South Melbourne | Verfahren zur bestimmung und behandlung von alzheimer-krankheit |
| GB9126874D0 (en) * | 1991-12-18 | 1992-02-19 | Wellcome Found | Medicaments |
| WO1995031199A1 (en) * | 1994-05-11 | 1995-11-23 | P.N. Gerolymatos S.A. | Use of clioquinol for treating helicobacter, including h. pylori, infections and related diseases |
| AU1153097A (en) * | 1996-06-07 | 1998-01-05 | Eisai Co. Ltd. | Stable polymorphs of donepezil (1-benzyl-4-{(5,6-dimethoxy-1-indanon)-2-yl}methylpiperidine ) hydrochloride and process for production |
| BR9711194A (pt) * | 1996-08-13 | 2000-01-11 | Gerolymatos P N Sa | Uso de agente quelante clioquinol para a fabricação de uma composição farmacêutica para o tratamento de doença de alzheimer. |
| JP2001514661A (ja) | 1997-03-11 | 2001-09-11 | ザ ジェネラル ホスピタル コーポレイション | アルツハイマー病の処置における使用のための薬剤の同定 |
| US5980882A (en) | 1997-04-16 | 1999-11-09 | Medeva Pharmaceuticals Manufacturing | Drug-resin complexes stabilized by chelating agents |
| US5980914A (en) | 1997-08-22 | 1999-11-09 | P.N. Gerolymatos S.A. | Clioquinol for the treatment of Parkinson's disease |
| US5994323A (en) | 1997-12-31 | 1999-11-30 | P.N. Gerolymatos S.A. | Pharmaceutical compositions comprising clioquinol in combination with vitamin B12 and therapeutic and prophylactic uses thereof |
| WO2000040244A1 (en) | 1999-01-07 | 2000-07-13 | P.N. Gerolymatos S.A. | Use of phanquinone for the treatment or prevention of memory impairment |
| AU2001250571A1 (en) | 2000-04-28 | 2001-11-12 | P.N. Gerolymatos S.A. | Treatment of pathological conditions influenced by the action of matrix metalloproteinases (mmps) using clioquinol |
| WO2001082912A2 (en) | 2000-04-28 | 2001-11-08 | Gerolymatos P N Sa | TREATMENT OF PATHOLOGICAL CONDITIONS INFLUENCED BY THE ACTION OF MATRIX METALLOPROTEINASES (MMPs) USING PHANQUINONE |
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- 1998-07-17 US US09/485,909 patent/US6670369B1/en not_active Expired - Fee Related
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- 1998-07-17 JP JP2000507371A patent/JP2001513558A/ja active Pending
- 1998-07-17 BR BR9814945-8A patent/BR9814945A/pt not_active Application Discontinuation
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