SK284708B6 - Použitie fanchinónu na výrobu farmaceutického prípravku na liečenie alebo prevenciu Alzheimerovej choroby, farmaceutický prípravok a kit obsahujúce fanchinón - Google Patents

Použitie fanchinónu na výrobu farmaceutického prípravku na liečenie alebo prevenciu Alzheimerovej choroby, farmaceutický prípravok a kit obsahujúce fanchinón Download PDF

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Publication number
SK284708B6
SK284708B6 SK206-2000A SK2062000A SK284708B6 SK 284708 B6 SK284708 B6 SK 284708B6 SK 2062000 A SK2062000 A SK 2062000A SK 284708 B6 SK284708 B6 SK 284708B6
Authority
SK
Slovakia
Prior art keywords
clioquinol
pharmaceutical composition
vitamin
fanquinone
disease
Prior art date
Application number
SK206-2000A
Other languages
English (en)
Slovak (sk)
Other versions
SK2062000A3 (en
Inventor
Michel Xilinas
Panayotis Nikolas Gerolymatos
Original Assignee
P.N. Gerolymatos S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by P.N. Gerolymatos S.A. filed Critical P.N. Gerolymatos S.A.
Publication of SK2062000A3 publication Critical patent/SK2062000A3/sk
Publication of SK284708B6 publication Critical patent/SK284708B6/sk

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
SK206-2000A 1997-08-21 1998-07-17 Použitie fanchinónu na výrobu farmaceutického prípravku na liečenie alebo prevenciu Alzheimerovej choroby, farmaceutický prípravok a kit obsahujúce fanchinón SK284708B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GR97100330 1997-08-21
GR97100507 1997-12-31
PCT/IB1998/001095 WO1999009981A1 (en) 1997-08-21 1998-07-17 Use of phanquinone for the treatment of alzheimer's disease

Publications (2)

Publication Number Publication Date
SK2062000A3 SK2062000A3 (en) 2000-08-14
SK284708B6 true SK284708B6 (sk) 2005-09-08

Family

ID=26316681

Family Applications (1)

Application Number Title Priority Date Filing Date
SK206-2000A SK284708B6 (sk) 1997-08-21 1998-07-17 Použitie fanchinónu na výrobu farmaceutického prípravku na liečenie alebo prevenciu Alzheimerovej choroby, farmaceutický prípravok a kit obsahujúce fanchinón

Country Status (24)

Country Link
US (2) US6670369B1 (cs)
EP (1) EP1007040B1 (cs)
JP (1) JP2001513558A (cs)
CN (1) CN1145482C (cs)
AT (1) ATE217191T1 (cs)
AU (1) AU741782B2 (cs)
BG (1) BG64300B1 (cs)
BR (1) BR9814945A (cs)
CA (1) CA2301706C (cs)
CZ (1) CZ299739B6 (cs)
DE (1) DE69805305T2 (cs)
DK (1) DK1007040T3 (cs)
EA (1) EA002526B1 (cs)
ES (1) ES2177024T3 (cs)
HU (1) HUP0004331A3 (cs)
IL (1) IL134263A (cs)
IS (1) IS1910B (cs)
NO (1) NO317770B1 (cs)
NZ (1) NZ502565A (cs)
PL (1) PL191208B1 (cs)
PT (1) PT1007040E (cs)
SK (1) SK284708B6 (cs)
TR (1) TR200000455T2 (cs)
WO (1) WO1999009981A1 (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7045531B1 (en) 1997-03-11 2006-05-16 The General Hospital Corporation Composition comprising a metal chelator and a method of treating amyloidosis by administering the metal chelator
US5994323A (en) * 1997-12-31 1999-11-30 P.N. Gerolymatos S.A. Pharmaceutical compositions comprising clioquinol in combination with vitamin B12 and therapeutic and prophylactic uses thereof
US6638711B1 (en) 1999-04-29 2003-10-28 The General Hospital Corporation Methods for identifying an agent that inhibits oxygen-dependent hydrogen peroxide formation activity but does not inhibit superoxide-dependent hydrogen peroxide formation
US6323218B1 (en) * 1998-03-11 2001-11-27 The General Hospital Corporation Agents for use in the treatment of Alzheimer's disease
ATE285235T1 (de) * 1999-01-07 2005-01-15 Gerolymatos P N Sa Verwendung von phanquinon zur behandlung und vorbeugung von gedächtnisschwund
AU2001250571A1 (en) * 2000-04-28 2001-11-12 P.N. Gerolymatos S.A. Treatment of pathological conditions influenced by the action of matrix metalloproteinases (mmps) using clioquinol
WO2001082912A2 (en) * 2000-04-28 2001-11-08 Gerolymatos P N Sa TREATMENT OF PATHOLOGICAL CONDITIONS INFLUENCED BY THE ACTION OF MATRIX METALLOPROTEINASES (MMPs) USING PHANQUINONE
WO2002015942A1 (en) 2000-08-18 2002-02-28 The General Hospital Corporation Method for the identification of agents that inhibit or promote cataracts and uses thereof
FR2818551B1 (fr) * 2000-12-22 2007-06-01 Claude Marc Pierre Hannoun Utilisation de chelateurs pour le traitement des maladies a prions
AU2002950217A0 (en) 2002-07-16 2002-09-12 Prana Biotechnology Limited 8- Hydroxy Quinoline Derivatives
WO2004080208A1 (ja) * 2003-03-11 2004-09-23 Kaneka Corporation コエンザイムq10を含有した水中油型乳化組成物、及びその製法
US20080207673A1 (en) * 2005-05-04 2008-08-28 Michel Xilinas Method for Treating Cancer, Coronary, Inflammatory and Macular Disease, Combining the Modulation of Zinc-and/or Copper Dependent Proteins
ES2651537T3 (es) * 2014-04-29 2018-01-29 Affiris Ag Tratamiento y prevención de la enfermedad de Alzheimer (AD)

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1617417A1 (de) * 1966-12-08 1971-03-25 Ciba Geigy Pharmazeutisches Praeparat
DE1804736A1 (de) * 1967-11-02 1969-06-26 Ciba Geigy Pharmazeutisches Praeparat
IL40311A (en) 1972-09-06 1973-04-30 Pharmaplantex Ltd Pharmaceutical preparation for the treatment of gastro-intestinal troubles containing phanquone and furazolidone
GB1472257A (en) 1973-09-10 1977-05-04 Christiaens Sa A Derivative of 4-hydroxy-5-azacoumarin
US5719197A (en) * 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US4981844A (en) * 1988-10-04 1991-01-01 University Of Cincinnati Method to improve immune response and resistance to infection following surgery by diet composition
US5091391A (en) 1990-08-16 1992-02-25 University Of Pittsburgh Of The Commonwealth System Of Higher Education Method of resisting neurodegenerative disorders
US6165500A (en) * 1990-08-24 2000-12-26 Idea Ag Preparation for the application of agents in mini-droplets
AP387A (en) * 1991-09-13 1995-07-31 Siegbert Heinrich Bissbort Therapeutical uses of L-methionine and compositions thereof.
WO1993010459A1 (en) 1991-11-12 1993-05-27 The University Of Melbourne A method for assaying and treating alzheimer's disease
GB9126874D0 (en) * 1991-12-18 1992-02-19 Wellcome Found Medicaments
WO1995031199A1 (en) * 1994-05-11 1995-11-23 P.N. Gerolymatos S.A. Use of clioquinol for treating helicobacter, including h. pylori, infections and related diseases
WO1997046526A1 (en) * 1996-06-07 1997-12-11 Eisai Co., Ltd. Stable polymorphs of donepezil (1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine) hydrochloride and process for production
TR199900293T2 (xx) * 1996-08-13 1999-06-21 P.N. Gerolymatos S.A. Alzheimer hastal��� tedavisi i�in bir farmas�tik bile�im �retmek �zere �elat maddesi clioquil'un kullan�m�.
WO1998040071A1 (en) 1997-03-11 1998-09-17 The General Hospital Corporation Identification of agents for use in the treatment of alzheimer's disease
US5980882A (en) * 1997-04-16 1999-11-09 Medeva Pharmaceuticals Manufacturing Drug-resin complexes stabilized by chelating agents
US5980914A (en) 1997-08-22 1999-11-09 P.N. Gerolymatos S.A. Clioquinol for the treatment of Parkinson's disease
US5994323A (en) 1997-12-31 1999-11-30 P.N. Gerolymatos S.A. Pharmaceutical compositions comprising clioquinol in combination with vitamin B12 and therapeutic and prophylactic uses thereof
ATE285235T1 (de) * 1999-01-07 2005-01-15 Gerolymatos P N Sa Verwendung von phanquinon zur behandlung und vorbeugung von gedächtnisschwund
AU2001250571A1 (en) 2000-04-28 2001-11-12 P.N. Gerolymatos S.A. Treatment of pathological conditions influenced by the action of matrix metalloproteinases (mmps) using clioquinol
WO2001082912A2 (en) 2000-04-28 2001-11-08 Gerolymatos P N Sa TREATMENT OF PATHOLOGICAL CONDITIONS INFLUENCED BY THE ACTION OF MATRIX METALLOPROTEINASES (MMPs) USING PHANQUINONE

Also Published As

Publication number Publication date
US6670369B1 (en) 2003-12-30
ATE217191T1 (de) 2002-05-15
EA200000242A1 (ru) 2000-08-28
IL134263A0 (en) 2001-04-30
CN1145482C (zh) 2004-04-14
HUP0004331A2 (hu) 2001-05-28
CA2301706C (en) 2005-10-04
EP1007040B1 (en) 2002-05-08
DE69805305D1 (de) 2002-06-13
HUP0004331A3 (en) 2001-09-28
CN1267218A (zh) 2000-09-20
NO20000771L (no) 2000-04-25
PL191208B1 (pl) 2006-03-31
IL134263A (en) 2006-04-10
AU741782B2 (en) 2001-12-06
IS5366A (is) 2000-01-28
EP1007040A1 (en) 2000-06-14
BG104179A (en) 2000-10-31
TR200000455T2 (tr) 2000-09-21
BG64300B1 (bg) 2004-09-30
BR9814945A (pt) 2000-09-05
WO1999009981A1 (en) 1999-03-04
NZ502565A (en) 2002-03-01
EA002526B1 (ru) 2002-06-27
AU8124198A (en) 1999-03-16
CA2301706A1 (en) 1999-03-04
HK1029937A1 (en) 2001-04-20
PT1007040E (pt) 2002-10-31
ES2177024T3 (es) 2002-12-01
IS1910B (is) 2003-12-31
DK1007040T3 (da) 2002-08-26
JP2001513558A (ja) 2001-09-04
CZ299739B6 (cs) 2008-11-05
US7629354B2 (en) 2009-12-08
NO317770B1 (no) 2004-12-13
CZ2000611A3 (cs) 2000-08-16
SK2062000A3 (en) 2000-08-14
US20050003018A1 (en) 2005-01-06
PL338673A1 (en) 2000-11-20
NO20000771D0 (no) 2000-02-16
DE69805305T2 (de) 2002-12-05

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20100717