NO316388B1 - Rekombinant DNA-molekyl fra Aspergillus niger, og en ekspresjonskassett ogen hybridvektor inneholdende denne - Google Patents
Rekombinant DNA-molekyl fra Aspergillus niger, og en ekspresjonskassett ogen hybridvektor inneholdende denne Download PDFInfo
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- NO316388B1 NO316388B1 NO19903812A NO903812A NO316388B1 NO 316388 B1 NO316388 B1 NO 316388B1 NO 19903812 A NO19903812 A NO 19903812A NO 903812 A NO903812 A NO 903812A NO 316388 B1 NO316388 B1 NO 316388B1
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- Prior art keywords
- dna
- pgi
- gene
- sequence
- niger
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- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 description 1
- 229960000553 somatostatin Drugs 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 238000004114 suspension culture Methods 0.000 description 1
- 230000009897 systematic effect Effects 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 229940104230 thymidine Drugs 0.000 description 1
- LCJVIYPJPCBWKS-NXPQJCNCSA-N thymosin Chemical compound SC[C@@H](N)C(=O)N[C@H](CO)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CO)C(=O)N[C@H](CO)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@H](CCC(O)=O)C(O)=O LCJVIYPJPCBWKS-NXPQJCNCSA-N 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 239000001226 triphosphate Substances 0.000 description 1
- 235000011178 triphosphate Nutrition 0.000 description 1
- UNXRWKVEANCORM-UHFFFAOYSA-N triphosphoric acid Chemical compound OP(O)(=O)OP(O)(=O)OP(O)(O)=O UNXRWKVEANCORM-UHFFFAOYSA-N 0.000 description 1
- 101150016309 trpC gene Proteins 0.000 description 1
- 101150108727 trpl gene Proteins 0.000 description 1
- 239000002753 trypsin inhibitor Substances 0.000 description 1
- 102000003390 tumor necrosis factor Human genes 0.000 description 1
- 238000009281 ultraviolet germicidal irradiation Methods 0.000 description 1
- 241000701447 unidentified baculovirus Species 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
- 241001430294 unidentified retrovirus Species 0.000 description 1
- 229960005356 urokinase Drugs 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
- 238000003260 vortexing Methods 0.000 description 1
- NLIVDORGVGAOOJ-MAHBNPEESA-M xylene cyanol Chemical compound [Na+].C1=C(C)C(NCC)=CC=C1C(\C=1C(=CC(OS([O-])=O)=CC=1)OS([O-])=O)=C\1C=C(C)\C(=[NH+]/CC)\C=C/1 NLIVDORGVGAOOJ-MAHBNPEESA-M 0.000 description 1
- 210000005253 yeast cell Anatomy 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L21/00—Marmalades, jams, jellies or the like; Products from apiculture; Preparation or treatment thereof
- A23L21/10—Marmalades; Jams; Jellies; Other similar fruit or vegetable compositions; Simulated fruit products
- A23L21/11—Marmalades; Jams; Jellies; Other similar fruit or vegetable compositions; Simulated fruit products obtained by enzymatic digestion of fruit or vegetable compositions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01015—Polygalacturonase (3.2.1.15)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898919884A GB8919884D0 (en) | 1989-09-02 | 1989-09-02 | Fungal expression system |
GB909013616A GB9013616D0 (en) | 1989-09-02 | 1990-06-19 | Fungal expression system |
Publications (3)
Publication Number | Publication Date |
---|---|
NO903812D0 NO903812D0 (no) | 1990-08-31 |
NO903812L NO903812L (no) | 1991-03-04 |
NO316388B1 true NO316388B1 (no) | 2004-01-19 |
Family
ID=26295856
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19903812A NO316388B1 (no) | 1989-09-02 | 1990-08-31 | Rekombinant DNA-molekyl fra Aspergillus niger, og en ekspresjonskassett ogen hybridvektor inneholdende denne |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0421919A3 (pt) |
JP (1) | JP3576549B2 (pt) |
AU (1) | AU640405B2 (pt) |
CA (1) | CA2024487C (pt) |
FI (1) | FI105206B (pt) |
HU (1) | HU220337B (pt) |
IE (1) | IE903180A1 (pt) |
IL (1) | IL95553A (pt) |
NO (1) | NO316388B1 (pt) |
NZ (1) | NZ235115A (pt) |
PT (1) | PT95171B (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5863783A (en) * | 1991-03-27 | 1999-01-26 | Gist-Brocades, N.V. | Cloning and expression of DNA molecules encoding arabinan-degrading enzymes of fungal origin |
JP2866739B2 (ja) * | 1991-12-09 | 1999-03-08 | ユニリーバー・ナームローゼ・ベンノートシヤープ | アスペルギルスエンドキシラナーゼ▲ii▼遺伝子に由来する発現/分泌調節領域を用い、形質転換したカビでタンパク質を産生して分泌させるための方法 |
WO1994014952A1 (en) * | 1992-12-23 | 1994-07-07 | Novo Nordisk A/S | An enzyme with polygalacturonase activity |
PL175670B1 (pl) * | 1992-12-24 | 1999-01-29 | Gist Brocades Nv | Oczyszczona i wyizolowana sekwencja DNA kodująca polipeptyd wykazujący aktywność enzymu poligalakturonazy (PGX) z Aspergillus tubigensis |
US5674728A (en) * | 1993-11-03 | 1997-10-07 | Novartis Corporation | Aspergillus niger vacuolar aspartyl protease |
WO1999041386A2 (en) * | 1998-02-10 | 1999-08-19 | Dsm N.V. | Novel endo-xylogalacturonase |
US6602696B1 (en) | 1998-09-18 | 2003-08-05 | Dsm N. V. | Aspergillus tubigensis polygalacturonase |
ATE389715T1 (de) | 1999-03-22 | 2008-04-15 | Novozymes As | Enzymatisches behandlungsverfahren |
EP2379717B1 (en) | 2008-12-19 | 2015-09-02 | DuPont Nutrition Biosciences ApS | Process for production of an enzyme product |
JP2023046320A (ja) * | 2021-09-22 | 2023-04-03 | 花王株式会社 | 糖化酵素の製造方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8626879D0 (en) * | 1986-11-11 | 1986-12-10 | Ici Plc | Dna |
GB8702475D0 (en) * | 1987-02-04 | 1987-03-11 | Ciba Geigy Ag | Expression system |
DE3908813A1 (de) * | 1989-03-17 | 1990-09-20 | Roehm Gmbh | Verfahren zur expression eines aus aspergillus niger stammenden gens in einem aspergillus |
-
1990
- 1990-08-24 EP EP19900810643 patent/EP0421919A3/en not_active Ceased
- 1990-08-31 FI FI904299A patent/FI105206B/fi active IP Right Grant
- 1990-08-31 IL IL9555390A patent/IL95553A/en active IP Right Grant
- 1990-08-31 CA CA002024487A patent/CA2024487C/en not_active Expired - Lifetime
- 1990-08-31 PT PT95171A patent/PT95171B/pt not_active IP Right Cessation
- 1990-08-31 NO NO19903812A patent/NO316388B1/no not_active IP Right Cessation
- 1990-08-31 IE IE318090A patent/IE903180A1/en unknown
- 1990-08-31 HU HU726/90A patent/HU220337B/hu unknown
- 1990-08-31 AU AU62054/90A patent/AU640405B2/en not_active Expired
- 1990-08-31 JP JP22848590A patent/JP3576549B2/ja not_active Expired - Lifetime
- 1990-08-31 NZ NZ235115A patent/NZ235115A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP0421919A3 (en) | 1992-04-15 |
EP0421919A2 (en) | 1991-04-10 |
JPH03224489A (ja) | 1991-10-03 |
NO903812D0 (no) | 1990-08-31 |
NZ235115A (en) | 1991-09-25 |
HUT54735A (en) | 1991-03-28 |
FI904299A0 (fi) | 1990-08-31 |
PT95171A (pt) | 1991-06-25 |
IE903180A1 (en) | 1991-03-13 |
AU6205490A (en) | 1991-03-07 |
CA2024487C (en) | 2008-04-29 |
JP3576549B2 (ja) | 2004-10-13 |
CA2024487A1 (en) | 1991-03-03 |
HU220337B (hu) | 2001-12-28 |
IL95553A (en) | 2005-12-18 |
AU640405B2 (en) | 1993-08-26 |
NO903812L (no) | 1991-03-04 |
PT95171B (pt) | 1997-09-30 |
FI105206B (fi) | 2000-06-30 |
IL95553A0 (en) | 1991-06-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK1K | Patent expired |