NO311965B1 - Anvendelse av antistoffer rettet mot variant -CD44- (vCD44)- overflateprotein for fremstilling av et farmasöytisk preparat - Google Patents
Anvendelse av antistoffer rettet mot variant -CD44- (vCD44)- overflateprotein for fremstilling av et farmasöytisk preparat Download PDFInfo
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- NO311965B1 NO311965B1 NO19924103A NO924103A NO311965B1 NO 311965 B1 NO311965 B1 NO 311965B1 NO 19924103 A NO19924103 A NO 19924103A NO 924103 A NO924103 A NO 924103A NO 311965 B1 NO311965 B1 NO 311965B1
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- 238000007920 subcutaneous administration Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 238000010189 synthetic method Methods 0.000 description 1
- 238000007910 systemic administration Methods 0.000 description 1
- 238000000954 titration curve Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
- 239000011534 wash buffer Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2884—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD44
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Biotechnology (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4134982A DE4134982A1 (de) | 1991-10-23 | 1991-10-23 | Verwendung von antikoerper enthaltenden praeparationen zur immunsuppression |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO924103D0 NO924103D0 (no) | 1992-10-22 |
| NO924103L NO924103L (no) | 1993-04-26 |
| NO311965B1 true NO311965B1 (no) | 2002-02-25 |
Family
ID=6443260
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19924103A NO311965B1 (no) | 1991-10-23 | 1992-10-22 | Anvendelse av antistoffer rettet mot variant -CD44- (vCD44)- overflateprotein for fremstilling av et farmasöytisk preparat |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5951982A (es) |
| EP (1) | EP0538754B1 (es) |
| JP (1) | JPH05310596A (es) |
| KR (1) | KR100252620B1 (es) |
| AT (1) | ATE162079T1 (es) |
| AU (1) | AU659687B2 (es) |
| CA (1) | CA2081150C (es) |
| DE (2) | DE4134982A1 (es) |
| DK (1) | DK0538754T3 (es) |
| ES (1) | ES2111031T3 (es) |
| GR (1) | GR3026526T3 (es) |
| HU (1) | HU216020B (es) |
| IL (1) | IL103510A0 (es) |
| NO (1) | NO311965B1 (es) |
| NZ (1) | NZ244851A (es) |
| TW (1) | TW273514B (es) |
| ZA (1) | ZA928162B (es) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5589458A (en) * | 1992-11-13 | 1996-12-31 | Thomas Jefferson University | Compounds that inhibit T cell proliferation and methods for using the same |
| WO1995000658A1 (en) * | 1993-06-18 | 1995-01-05 | Sirpa Jalkanen | COMPOSITIONS AND DIAGNOSTIC METHODS USING MONOCLONAL ANTIBODIES AGAINST CD44v6 |
| DE4326573A1 (de) * | 1993-08-07 | 1995-02-23 | Boehringer Ingelheim Int | Durch Exon v5 des CD44-Gens kodierte Polypeptide als Targets für Immuntherapie und Immunszintigraphie von Tumoren |
| DE4431297A1 (de) * | 1994-09-02 | 1996-03-07 | Boehringer Ingelheim Int | Monoklonaler Antikörper gegen CD44v6 |
| DE19540515C1 (de) * | 1995-10-31 | 1997-02-06 | Boehringer Ingelheim Int | Tumortherapie durch adoptiven Transfer CD44v-spezifischer zytotoxischer T-Lymphozyten |
| US6440733B1 (en) * | 1996-02-15 | 2002-08-27 | Chugai Seiyaku Kabushiki Kaisha | Monoclonal antibodies recognizing antigens on the surface of endothelial cells of tumor vessel |
| US6136311A (en) | 1996-05-06 | 2000-10-24 | Cornell Research Foundation, Inc. | Treatment and diagnosis of cancer |
| DE19652815C2 (de) * | 1996-12-18 | 1999-11-11 | Karlsruhe Forschzent | Mittel zur Identifizierung und Therapie metastasierender Tumore |
| DE19653607A1 (de) | 1996-12-20 | 1998-06-25 | Boehringer Ingelheim Int | Verfahren zur Diagnose und Therapie von Hodgkin-Lymphomen |
| DE19708713C2 (de) * | 1997-03-04 | 2002-11-28 | Boehringer Ingelheim Int | Verwendung von anti-CD44 Antikörpern enthaltenden Präparationen zur Behandlung bestimmter Tumore und zur Unterdrückung von Immunreaktionen |
| IL121656A0 (en) * | 1997-08-29 | 1998-02-08 | Yissum Res Dev Co | Diagnosis prevention and treatment of diabetes |
| US7534605B2 (en) | 1999-06-08 | 2009-05-19 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases |
| US20040110933A1 (en) * | 2002-09-13 | 2004-06-10 | Dyax Corporation | CD44-binding ligands |
| US9701754B1 (en) | 2002-10-23 | 2017-07-11 | City Of Hope | Covalent disulfide-linked diabodies and uses thereof |
| CA2560200A1 (en) * | 2004-03-17 | 2005-09-22 | Academisch Ziekenhuis Bij De Universiteit Van Amsterdam | Cd44-targeting for reducing/preventing ischemia-reperfusion-injury |
| EP1924606A4 (en) | 2005-08-25 | 2010-01-13 | Repair Technologies Inc | DEVICES, COMPOSITIONS AND METHODS FOR PROTECTING AND REPAIRING CELLS AND TISSUE |
| ES2363891T3 (es) | 2006-03-20 | 2011-08-18 | The Regents Of The University Of California | Anticuerpos contra el antígeno de células troncales de la próstata (psca) modificados genéticamente para el direccionamiento al cáncer. |
| WO2009032949A2 (en) | 2007-09-04 | 2009-03-12 | The Regents Of The University Of California | High affinity anti-prostate stem cell antigen (psca) antibodies for cancer targeting and detection |
| WO2010058396A1 (en) | 2008-11-19 | 2010-05-27 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | A cd44vra antibody and diagnostic and therapeutic methods using same |
| EP2398504B1 (en) | 2009-02-17 | 2018-11-28 | Cornell Research Foundation, Inc. | Methods and kits for diagnosis of cancer and prediction of therapeutic value |
| WO2011069019A2 (en) | 2009-12-02 | 2011-06-09 | David Ho | J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen (psma) and methods for their use |
| PT2886126T (pt) | 2013-12-23 | 2017-09-13 | Exchange Imaging Tech Gmbh | Nanopartícula conjugada a péptidos de ligação a cd44 |
| RU2017104284A (ru) | 2014-07-15 | 2018-08-15 | Йиссум Рисеч Девелопмент Компани Оф Зе Хебрю Юниверсити Оф Джерусалем Лтд. | Выделенные полипептиды cd44 и их применение |
| KR20180050321A (ko) | 2015-08-07 | 2018-05-14 | 이미지냅 인코포레이티드 | 분자를 표적화하기 위한 항원 결합 구조체 |
| US11266745B2 (en) | 2017-02-08 | 2022-03-08 | Imaginab, Inc. | Extension sequences for diabodies |
| US11313243B2 (en) | 2018-07-12 | 2022-04-26 | Rolls-Royce North American Technologies, Inc. | Non-continuous abradable coatings |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3852236T2 (de) * | 1987-08-11 | 1995-04-06 | Univ Leland Stanford Junior | Verfahren zur Kontrolle der Leukozyten-Extravasation. |
| DE4014510A1 (de) * | 1990-05-07 | 1991-11-14 | Kernforschungsz Karlsruhe | Variante cd44-oberflaechenproteine, diese kodierende c-dna-sequenzen, antikoerper gegen diese proteine sowie ihre verwendung in der diagnostik und therapie |
| CA2059824A1 (en) * | 1991-02-26 | 1992-08-27 | Thomas M. Aune | Hybridomas and monoclonal antibodies that inhibit anti-cd3-stimulated t cell proliferation |
| WO1995000658A1 (en) * | 1993-06-18 | 1995-01-05 | Sirpa Jalkanen | COMPOSITIONS AND DIAGNOSTIC METHODS USING MONOCLONAL ANTIBODIES AGAINST CD44v6 |
-
1991
- 1991-10-23 DE DE4134982A patent/DE4134982A1/de not_active Withdrawn
-
1992
- 1992-10-07 TW TW081107971A patent/TW273514B/zh active
- 1992-10-17 ES ES92117775T patent/ES2111031T3/es not_active Expired - Lifetime
- 1992-10-17 EP EP92117775A patent/EP0538754B1/de not_active Expired - Lifetime
- 1992-10-17 DE DE59209129T patent/DE59209129D1/de not_active Expired - Fee Related
- 1992-10-17 DK DK92117775.4T patent/DK0538754T3/da active
- 1992-10-17 AT AT92117775T patent/ATE162079T1/de not_active IP Right Cessation
- 1992-10-21 NZ NZ244851A patent/NZ244851A/en unknown
- 1992-10-22 AU AU27244/92A patent/AU659687B2/en not_active Ceased
- 1992-10-22 NO NO19924103A patent/NO311965B1/no not_active IP Right Cessation
- 1992-10-22 CA CA002081150A patent/CA2081150C/en not_active Expired - Fee Related
- 1992-10-22 IL IL103510A patent/IL103510A0/xx unknown
- 1992-10-22 KR KR1019920019468A patent/KR100252620B1/ko not_active IP Right Cessation
- 1992-10-22 ZA ZA928162A patent/ZA928162B/xx unknown
- 1992-10-22 HU HUP9203337A patent/HU216020B/hu not_active IP Right Cessation
- 1992-10-23 JP JP4307913A patent/JPH05310596A/ja active Pending
-
1994
- 1994-12-20 US US08/359,850 patent/US5951982A/en not_active Expired - Lifetime
-
1998
- 1998-04-03 GR GR980400710T patent/GR3026526T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0538754A2 (de) | 1993-04-28 |
| DE4134982A1 (de) | 1993-04-29 |
| IL103510A0 (en) | 1993-03-15 |
| KR100252620B1 (ko) | 2000-09-01 |
| EP0538754B1 (de) | 1998-01-14 |
| DE59209129D1 (de) | 1998-02-19 |
| ZA928162B (en) | 1993-05-05 |
| GR3026526T3 (en) | 1998-07-31 |
| ATE162079T1 (de) | 1998-01-15 |
| KR930007460A (ko) | 1993-05-20 |
| CA2081150A1 (en) | 1993-04-24 |
| JPH05310596A (ja) | 1993-11-22 |
| HUT63063A (en) | 1993-07-28 |
| AU659687B2 (en) | 1995-05-25 |
| TW273514B (es) | 1996-04-01 |
| CA2081150C (en) | 2001-04-10 |
| NO924103L (no) | 1993-04-26 |
| ES2111031T3 (es) | 1998-03-01 |
| EP0538754A3 (en) | 1994-05-25 |
| US5951982A (en) | 1999-09-14 |
| AU2724492A (en) | 1993-04-29 |
| DK0538754T3 (da) | 1998-03-30 |
| HU216020B (hu) | 1999-04-28 |
| NO924103D0 (no) | 1992-10-22 |
| NZ244851A (en) | 1997-07-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |