ES2111031T3 - Uso de preparaciones que contienen anticuerpos para la inmunosupresion. - Google Patents

Uso de preparaciones que contienen anticuerpos para la inmunosupresion.

Info

Publication number
ES2111031T3
ES2111031T3 ES92117775T ES92117775T ES2111031T3 ES 2111031 T3 ES2111031 T3 ES 2111031T3 ES 92117775 T ES92117775 T ES 92117775T ES 92117775 T ES92117775 T ES 92117775T ES 2111031 T3 ES2111031 T3 ES 2111031T3
Authority
ES
Spain
Prior art keywords
immunosuppression
preparations containing
containing antibodies
preparations
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92117775T
Other languages
English (en)
Inventor
Margot Zoeller
Peter Herrlich
Helmut Ponta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deutsches Krebsforschungszentrum DKFZ
Boehringer Ingelheim International GmbH
Forschungszentrum Karlsruhe GmbH
Original Assignee
Kernforschungszentrum Karlsruhe GmbH
Deutsches Krebsforschungszentrum DKFZ
Boehringer Ingelheim International GmbH
Forschungszentrum Karlsruhe GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kernforschungszentrum Karlsruhe GmbH, Deutsches Krebsforschungszentrum DKFZ, Boehringer Ingelheim International GmbH, Forschungszentrum Karlsruhe GmbH filed Critical Kernforschungszentrum Karlsruhe GmbH
Application granted granted Critical
Publication of ES2111031T3 publication Critical patent/ES2111031T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2884—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD44
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Abstract

LA PRESENTE INVENCION SE REFIERE AL EMPLEO DE PREPARADOS QUE CONTIENEN ANTICUERPOS DIRIGIDOS CONTRA EL VCD44 PARA LA INMUNOSUPRESION.
ES92117775T 1991-10-23 1992-10-17 Uso de preparaciones que contienen anticuerpos para la inmunosupresion. Expired - Lifetime ES2111031T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4134982A DE4134982A1 (de) 1991-10-23 1991-10-23 Verwendung von antikoerper enthaltenden praeparationen zur immunsuppression

Publications (1)

Publication Number Publication Date
ES2111031T3 true ES2111031T3 (es) 1998-03-01

Family

ID=6443260

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92117775T Expired - Lifetime ES2111031T3 (es) 1991-10-23 1992-10-17 Uso de preparaciones que contienen anticuerpos para la inmunosupresion.

Country Status (17)

Country Link
US (1) US5951982A (es)
EP (1) EP0538754B1 (es)
JP (1) JPH05310596A (es)
KR (1) KR100252620B1 (es)
AT (1) ATE162079T1 (es)
AU (1) AU659687B2 (es)
CA (1) CA2081150C (es)
DE (2) DE4134982A1 (es)
DK (1) DK0538754T3 (es)
ES (1) ES2111031T3 (es)
GR (1) GR3026526T3 (es)
HU (1) HU216020B (es)
IL (1) IL103510A0 (es)
NO (1) NO311965B1 (es)
NZ (1) NZ244851A (es)
TW (1) TW273514B (es)
ZA (1) ZA928162B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589458A (en) * 1992-11-13 1996-12-31 Thomas Jefferson University Compounds that inhibit T cell proliferation and methods for using the same
DE69406664T2 (de) * 1993-06-18 1998-06-04 Biotie Therapies Oy Zusammensetzungen und diagnostische verfahren unter verwendung von monoklonalen antikoerpern gegen cd44v6
DE4326573A1 (de) * 1993-08-07 1995-02-23 Boehringer Ingelheim Int Durch Exon v5 des CD44-Gens kodierte Polypeptide als Targets für Immuntherapie und Immunszintigraphie von Tumoren
DE4431297A1 (de) * 1994-09-02 1996-03-07 Boehringer Ingelheim Int Monoklonaler Antikörper gegen CD44v6
DE19540515C1 (de) * 1995-10-31 1997-02-06 Boehringer Ingelheim Int Tumortherapie durch adoptiven Transfer CD44v-spezifischer zytotoxischer T-Lymphozyten
EP0881299A4 (en) * 1996-02-15 2004-12-15 Chugai Seiyakukabushiki Kaisha MONOCLONAL ANTIBODIES RECOGNIZING ANTIGENS PRESENT ON THE SURFACE OF ENDOTHELIAL CELLS OF A TUMOR VESSEL
US6136311A (en) 1996-05-06 2000-10-24 Cornell Research Foundation, Inc. Treatment and diagnosis of cancer
DE19652815C2 (de) * 1996-12-18 1999-11-11 Karlsruhe Forschzent Mittel zur Identifizierung und Therapie metastasierender Tumore
DE19653607A1 (de) 1996-12-20 1998-06-25 Boehringer Ingelheim Int Verfahren zur Diagnose und Therapie von Hodgkin-Lymphomen
DE19708713C2 (de) * 1997-03-04 2002-11-28 Boehringer Ingelheim Int Verwendung von anti-CD44 Antikörpern enthaltenden Präparationen zur Behandlung bestimmter Tumore und zur Unterdrückung von Immunreaktionen
IL121656A0 (en) * 1997-08-29 1998-02-08 Yissum Res Dev Co Diagnosis prevention and treatment of diabetes
US7534605B2 (en) * 1999-06-08 2009-05-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases
AU2003272511A1 (en) * 2002-09-13 2004-04-30 Dyax Corporation Cd44-binding ligands
US9701754B1 (en) 2002-10-23 2017-07-11 City Of Hope Covalent disulfide-linked diabodies and uses thereof
CA2560200A1 (en) * 2004-03-17 2005-09-22 Academisch Ziekenhuis Bij De Universiteit Van Amsterdam Cd44-targeting for reducing/preventing ischemia-reperfusion-injury
EP1924606A4 (en) 2005-08-25 2010-01-13 Repair Technologies Inc DEVICES, COMPOSITIONS AND METHODS FOR PROTECTING AND REPAIRING CELLS AND TISSUE
EP1996716B1 (en) 2006-03-20 2011-05-11 The Regents of the University of California Engineered anti-prostate stem cell antigen (psca) antibodies for cancer targeting
JP6126773B2 (ja) 2007-09-04 2017-05-10 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 癌のターゲッティングおよび検出のための高親和性抗前立腺幹細胞抗原（ｐｓｃａ）抗体
WO2010058396A1 (en) 2008-11-19 2010-05-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. A cd44vra antibody and diagnostic and therapeutic methods using same
WO2010096486A1 (en) 2009-02-17 2010-08-26 Cornell Research Foundation, Inc. Methods and kits for diagnosis of cancer and prediction of therapeutic value
CA2782333C (en) 2009-12-02 2019-06-04 Imaginab, Inc. J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen (psma) and methods for their use
PL2886126T3 (pl) 2013-12-23 2017-11-30 Exchange Imaging Technologies Gmbh Nanocząstka sprzężona z peptydami wiążącymi CD44
HUE049261T2 (hu) 2014-07-15 2020-09-28 Yissum Research And Development Company Of The Hebrew Univ Of Jerusalem Ltd CD44 izolált polipeptidek és alkalmazásaik
NZ739721A (en) 2015-08-07 2019-09-27 Imaginab Inc Antigen binding constructs to target molecules
WO2018147960A1 (en) 2017-02-08 2018-08-16 Imaginab, Inc. Extension sequences for diabodies
US11313243B2 (en) 2018-07-12 2022-04-26 Rolls-Royce North American Technologies, Inc. Non-continuous abradable coatings

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE114478T1 (de) * 1987-08-11 1994-12-15 Univ Leland Stanford Junior Verfahren zur kontrolle der leukozyten- extravasation.
DE4014510A1 (de) * 1990-05-07 1991-11-14 Kernforschungsz Karlsruhe Variante cd44-oberflaechenproteine, diese kodierende c-dna-sequenzen, antikoerper gegen diese proteine sowie ihre verwendung in der diagnostik und therapie
CA2059824A1 (en) * 1991-02-26 1992-08-27 Thomas M. Aune Hybridomas and monoclonal antibodies that inhibit anti-cd3-stimulated t cell proliferation
DE69406664T2 (de) * 1993-06-18 1998-06-04 Biotie Therapies Oy Zusammensetzungen und diagnostische verfahren unter verwendung von monoklonalen antikoerpern gegen cd44v6

Also Published As

Publication number Publication date
EP0538754A2 (de) 1993-04-28
NO924103D0 (no) 1992-10-22
ATE162079T1 (de) 1998-01-15
NO924103L (no) 1993-04-26
CA2081150A1 (en) 1993-04-24
IL103510A0 (en) 1993-03-15
KR930007460A (ko) 1993-05-20
JPH05310596A (ja) 1993-11-22
AU2724492A (en) 1993-04-29
DE59209129D1 (de) 1998-02-19
CA2081150C (en) 2001-04-10
GR3026526T3 (en) 1998-07-31
DE4134982A1 (de) 1993-04-29
US5951982A (en) 1999-09-14
EP0538754A3 (en) 1994-05-25
NO311965B1 (no) 2002-02-25
HUT63063A (en) 1993-07-28
EP0538754B1 (de) 1998-01-14
NZ244851A (en) 1997-07-27
TW273514B (es) 1996-04-01
KR100252620B1 (ko) 2000-09-01
HU216020B (hu) 1999-04-28
ZA928162B (en) 1993-05-05
AU659687B2 (en) 1995-05-25
DK0538754T3 (da) 1998-03-30

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