NO308619B1 - Rekombinante DNA-molekyler og fremgangsmÕte for fremstilling av heterologt protein - Google Patents
Rekombinante DNA-molekyler og fremgangsmÕte for fremstilling av heterologt protein Download PDFInfo
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
- C12N9/60—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from yeast
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/04—Fusion polypeptide containing a localisation/targetting motif containing an ER retention signal such as a C-terminal HDEL motif
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP91810984 | 1991-12-16 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO924847D0 NO924847D0 (no) | 1992-12-15 |
| NO924847L NO924847L (no) | 1993-06-17 |
| NO308619B1 true NO308619B1 (no) | 2000-10-02 |
Family
ID=8208912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO924847A NO308619B1 (no) | 1991-12-16 | 1992-12-15 | Rekombinante DNA-molekyler og fremgangsmÕte for fremstilling av heterologt protein |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US5501975A (el) |
| EP (1) | EP0548012B1 (el) |
| JP (1) | JP3305781B2 (el) |
| KR (1) | KR100270283B1 (el) |
| AT (1) | ATE157703T1 (el) |
| AU (1) | AU667852B2 (el) |
| CA (1) | CA2085308C (el) |
| DE (1) | DE69222013T2 (el) |
| DK (1) | DK0548012T3 (el) |
| ES (1) | ES2107520T3 (el) |
| FI (1) | FI105482B (el) |
| GR (1) | GR3025324T3 (el) |
| IL (1) | IL104075A (el) |
| MX (1) | MX9207291A (el) |
| NO (1) | NO308619B1 (el) |
| NZ (1) | NZ245469A (el) |
| ZA (1) | ZA929711B (el) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9404270D0 (en) * | 1994-03-05 | 1994-04-20 | Delta Biotechnology Ltd | Yeast strains and modified albumins |
| NZ304538A (en) * | 1995-02-27 | 1999-08-30 | Abbott Lab | Process for producing a modified recombinant protein in a host cell comprising preparing a single vector encoding both the exogenous protein and an enzyme capable of modifying the exogenous protein |
| CA2213734A1 (en) * | 1995-02-27 | 1996-09-06 | Abbott Laboratories | A plasmid for expressing modified recombinant proteins in a bacterial system |
| US5942254A (en) * | 1995-02-27 | 1999-08-24 | Abbott Laboratories | Phosphorylated recombinant human β-casein expressed in a bacterial system |
| US5710044A (en) * | 1995-02-27 | 1998-01-20 | Abbott Laboratories | Plasmid for expressing phosphorylated recombinant proteins in a bacterial system |
| US5807702A (en) * | 1995-02-27 | 1998-09-15 | Abbott Laboratories | Method for expressing phosphorylated recombinant human β-casein in a bacterial system |
| AT404838B (de) * | 1995-11-24 | 1999-03-25 | Immuno Ag | Herstellung von proteinen aus pro-proteinen durch fusionsproteine abgeleitet von furin oder furinanalogen |
| FR2751000B1 (fr) | 1996-07-12 | 1998-10-30 | Inst Nat Sante Rech Med | Adn specifiques des bacteries de l'espece neisseria meningitidis, leurs procedes d'obtention et leurs applications biologiques |
| WO2000028065A1 (en) * | 1998-11-06 | 2000-05-18 | Novo Nordisk A/S | Method for the production of fvii |
| WO2002000856A2 (en) | 2000-06-30 | 2002-01-03 | Flanders Interuniversity Institute For Biotechnology (Vib) | Protein glycosylation modification in pichia pastoris |
| DE10221411B4 (de) * | 2002-05-14 | 2004-07-08 | GSF-Forschungszentrum für Umwelt und Gesundheit GmbH | Rekombinantes Fowlpox-Virus |
| US20040117874A1 (en) * | 2002-10-15 | 2004-06-17 | Jianjun Yang | Methods for accumulating translocated proteins |
| US7507573B2 (en) | 2003-11-14 | 2009-03-24 | Vib, Vzw | Modification of protein glycosylation in methylotrophic yeast |
| JP5112064B2 (ja) * | 2004-05-21 | 2013-01-09 | エムオー バイオ ラボラトリーズ インコーポレイテッド | 環境サンプルおよび生物学的サンプル中の核酸から夾雑物を除去するためのキットおよび方法 |
| US20080082338A1 (en) * | 2006-09-29 | 2008-04-03 | O'neil Michael P | Systems and methods for secure voice identification and medical device interface |
| RU2663587C2 (ru) | 2013-03-06 | 2018-08-07 | ГЛЭКСОСМИТКЛАЙН ЭлЭлСи | Клетки-хозяева и способы использования |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4885166A (en) * | 1985-06-11 | 1989-12-05 | Ciba-Geigy Corporation | Hybrid interferons |
| US5391485A (en) * | 1985-08-06 | 1995-02-21 | Immunex Corporation | DNAs encoding analog GM-CSF molecules displaying resistance to proteases which cleave at adjacent dibasic residues |
| FI100106B (fi) * | 1986-12-05 | 1997-09-30 | Novartis Ag | Menetelmä plasminogeenin yksisäikeisen yhdistelmäaktivaattorin valmist amiseksi |
| JP2643968B2 (ja) * | 1988-02-03 | 1997-08-25 | サントリー株式会社 | Ｋｅｘ２エンドプロテアーゼ及びその製造方法 |
-
1992
- 1992-12-08 DK DK92810964.4T patent/DK0548012T3/da active
- 1992-12-08 DE DE69222013T patent/DE69222013T2/de not_active Expired - Lifetime
- 1992-12-08 ES ES92810964T patent/ES2107520T3/es not_active Expired - Lifetime
- 1992-12-08 EP EP92810964A patent/EP0548012B1/en not_active Expired - Lifetime
- 1992-12-08 AT AT92810964T patent/ATE157703T1/de active
- 1992-12-10 AU AU30071/92A patent/AU667852B2/en not_active Expired
- 1992-12-13 IL IL10407592A patent/IL104075A/xx not_active IP Right Cessation
- 1992-12-14 FI FI925678A patent/FI105482B/fi not_active IP Right Cessation
- 1992-12-14 CA CA002085308A patent/CA2085308C/en not_active Expired - Lifetime
- 1992-12-14 NZ NZ245469A patent/NZ245469A/en unknown
- 1992-12-14 KR KR1019920024117A patent/KR100270283B1/ko not_active IP Right Cessation
- 1992-12-15 JP JP33410492A patent/JP3305781B2/ja not_active Expired - Lifetime
- 1992-12-15 MX MX9207291A patent/MX9207291A/es unknown
- 1992-12-15 NO NO924847A patent/NO308619B1/no not_active IP Right Cessation
- 1992-12-15 ZA ZA929711A patent/ZA929711B/xx unknown
-
1994
- 1994-10-24 US US08/328,961 patent/US5501975A/en not_active Expired - Lifetime
-
1995
- 1995-06-05 US US08/462,397 patent/US5618690A/en not_active Expired - Lifetime
-
1997
- 1997-11-07 GR GR970402966T patent/GR3025324T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2085308A1 (en) | 1993-06-17 |
| IL104075A (en) | 2003-01-12 |
| IL104075A0 (en) | 1993-05-13 |
| FI925678A (fi) | 1993-06-17 |
| ZA929711B (en) | 1993-06-16 |
| NO924847L (no) | 1993-06-17 |
| NZ245469A (en) | 1995-03-28 |
| EP0548012B1 (en) | 1997-09-03 |
| MX9207291A (es) | 1993-07-01 |
| DE69222013T2 (de) | 1998-01-29 |
| DE69222013D1 (de) | 1997-10-09 |
| NO924847D0 (no) | 1992-12-15 |
| KR100270283B1 (ko) | 2000-11-01 |
| US5501975A (en) | 1996-03-26 |
| AU667852B2 (en) | 1996-04-18 |
| US5618690A (en) | 1997-04-08 |
| AU3007192A (en) | 1993-06-17 |
| FI105482B (fi) | 2000-08-31 |
| DK0548012T3 (da) | 1998-04-14 |
| FI925678A0 (fi) | 1992-12-14 |
| ES2107520T3 (es) | 1997-12-01 |
| JPH06197787A (ja) | 1994-07-19 |
| KR930013115A (ko) | 1993-07-21 |
| JP3305781B2 (ja) | 2002-07-24 |
| EP0548012A1 (en) | 1993-06-23 |
| GR3025324T3 (en) | 1998-02-27 |
| ATE157703T1 (de) | 1997-09-15 |
| CA2085308C (en) | 2003-12-02 |
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| MK1K | Patent expired |