NO924847L - Dna-molekyler og verter - Google Patents

Dna-molekyler og verter

Info

Publication number
NO924847L
NO924847L NO92924847A NO924847A NO924847L NO 924847 L NO924847 L NO 924847L NO 92924847 A NO92924847 A NO 92924847A NO 924847 A NO924847 A NO 924847A NO 924847 L NO924847 L NO 924847L
Authority
NO
Norway
Prior art keywords
dna molecules
hosts
endoplasmic reticulum
dibasic
endoprotease
Prior art date
Application number
NO92924847A
Other languages
English (en)
Other versions
NO308619B1 (no
NO924847D0 (no
Inventor
Bhabatosh Chaudhuri
Christine Stephan
Peter Seeboth
Howard Riezman
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO924847D0 publication Critical patent/NO924847D0/no
Publication of NO924847L publication Critical patent/NO924847L/no
Publication of NO308619B1 publication Critical patent/NO308619B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/60—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/04—Fusion polypeptide containing a localisation/targetting motif containing an ER retention signal such as a C-terminal HDEL motif
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
NO924847A 1991-12-16 1992-12-15 Rekombinante DNA-molekyler og fremgangsmÕte for fremstilling av heterologt protein NO308619B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91810984 1991-12-16

Publications (3)

Publication Number Publication Date
NO924847D0 NO924847D0 (no) 1992-12-15
NO924847L true NO924847L (no) 1993-06-17
NO308619B1 NO308619B1 (no) 2000-10-02

Family

ID=8208912

Family Applications (1)

Application Number Title Priority Date Filing Date
NO924847A NO308619B1 (no) 1991-12-16 1992-12-15 Rekombinante DNA-molekyler og fremgangsmÕte for fremstilling av heterologt protein

Country Status (17)

Country Link
US (2) US5501975A (no)
EP (1) EP0548012B1 (no)
JP (1) JP3305781B2 (no)
KR (1) KR100270283B1 (no)
AT (1) ATE157703T1 (no)
AU (1) AU667852B2 (no)
CA (1) CA2085308C (no)
DE (1) DE69222013T2 (no)
DK (1) DK0548012T3 (no)
ES (1) ES2107520T3 (no)
FI (1) FI105482B (no)
GR (1) GR3025324T3 (no)
IL (1) IL104075A (no)
MX (1) MX9207291A (no)
NO (1) NO308619B1 (no)
NZ (1) NZ245469A (no)
ZA (1) ZA929711B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9404270D0 (en) * 1994-03-05 1994-04-20 Delta Biotechnology Ltd Yeast strains and modified albumins
EP0812362A1 (en) * 1995-02-27 1997-12-17 Abbott Laboratories A plasmid for expressing modified recombinant proteins in a bacterial system
US5942254A (en) * 1995-02-27 1999-08-24 Abbott Laboratories Phosphorylated recombinant human β-casein expressed in a bacterial system
EP0812361A1 (en) * 1995-02-27 1997-12-17 Abbott Laboratories A method for expressing modified recombinant proteins in a bacterial system
US5710044A (en) * 1995-02-27 1998-01-20 Abbott Laboratories Plasmid for expressing phosphorylated recombinant proteins in a bacterial system
US5807702A (en) * 1995-02-27 1998-09-15 Abbott Laboratories Method for expressing phosphorylated recombinant human β-casein in a bacterial system
AT404838B (de) * 1995-11-24 1999-03-25 Immuno Ag Herstellung von proteinen aus pro-proteinen durch fusionsproteine abgeleitet von furin oder furinanalogen
FR2751000B1 (fr) 1996-07-12 1998-10-30 Inst Nat Sante Rech Med Adn specifiques des bacteries de l'espece neisseria meningitidis, leurs procedes d'obtention et leurs applications biologiques
DE69939548D1 (de) * 1998-11-06 2008-10-23 Novo Nordisk Healthcare Ag Verfahren zur herstellung von faktor vii
AU7765801A (en) 2000-06-30 2002-01-08 Flanders Interuniversity Inst Protein glycosylation modification in pichia pastoris
DE10221411B4 (de) * 2002-05-14 2004-07-08 GSF-Forschungszentrum für Umwelt und Gesundheit GmbH Rekombinantes Fowlpox-Virus
US20040117874A1 (en) * 2002-10-15 2004-06-17 Jianjun Yang Methods for accumulating translocated proteins
US7507573B2 (en) 2003-11-14 2009-03-24 Vib, Vzw Modification of protein glycosylation in methylotrophic yeast
CA2567599C (en) * 2004-05-21 2015-07-21 Mo Bio Laboratories, Inc. Kits and processes for removing contaminants from nucleic acids in environmental and biological samples
US20080082338A1 (en) * 2006-09-29 2008-04-03 O'neil Michael P Systems and methods for secure voice identification and medical device interface
AU2014225678B2 (en) 2013-03-06 2016-11-17 Glaxosmithkline Llc Host cells and methods of use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0205404B1 (en) * 1985-06-11 1992-07-15 Ciba-Geigy Ag Hybrid interferons
US5391485A (en) * 1985-08-06 1995-02-21 Immunex Corporation DNAs encoding analog GM-CSF molecules displaying resistance to proteases which cleave at adjacent dibasic residues
FI100106B (fi) * 1986-12-05 1997-09-30 Novartis Ag Menetelmä plasminogeenin yksisäikeisen yhdistelmäaktivaattorin valmist amiseksi
JP2643968B2 (ja) * 1988-02-03 1997-08-25 サントリー株式会社 Ｋｅｘ２エンドプロテアーゼ及びその製造方法

Also Published As

Publication number Publication date
FI925678A (fi) 1993-06-17
AU3007192A (en) 1993-06-17
NO308619B1 (no) 2000-10-02
CA2085308C (en) 2003-12-02
US5501975A (en) 1996-03-26
AU667852B2 (en) 1996-04-18
ES2107520T3 (es) 1997-12-01
JPH06197787A (ja) 1994-07-19
KR100270283B1 (ko) 2000-11-01
MX9207291A (es) 1993-07-01
US5618690A (en) 1997-04-08
DE69222013D1 (de) 1997-10-09
DE69222013T2 (de) 1998-01-29
DK0548012T3 (da) 1998-04-14
CA2085308A1 (en) 1993-06-17
EP0548012A1 (en) 1993-06-23
FI105482B (fi) 2000-08-31
FI925678A0 (fi) 1992-12-14
KR930013115A (ko) 1993-07-21
NZ245469A (en) 1995-03-28
NO924847D0 (no) 1992-12-15
ZA929711B (en) 1993-06-16
GR3025324T3 (en) 1998-02-27
EP0548012B1 (en) 1997-09-03
ATE157703T1 (de) 1997-09-15
IL104075A (en) 2003-01-12
JP3305781B2 (ja) 2002-07-24
IL104075A0 (en) 1993-05-13

Similar Documents

Publication Publication Date Title
NO924847D0 (no) Dna-molekyler og verter
DK0939767T3 (da) Procin faktor VIII og hybrider deraf
DK217889D0 (da) Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for desacetoxycephalosporin c synthetase
EP0795605A4 (en) DENAHRED LOW-DENSITY LIPOPROTEIN (LDL) RECEPTOR
SG43128A1 (en) Code excitation linear predictive (celp) encoder and decoder
MX9201571A (es) Resinas curables con agentes anti-espuma soportados en material solido.
DK0550895T3 (da) 4,13-dioxabicyclo(8.2.1)-tridecenonderivater, fremgangsmåde og mellemprodukter til fremstilling deraf og lægemidler, der indeholder disse forbindelser
ATE252156T1 (de) Neue schimmel-protease
ES2196019T3 (es) Proteasa fungica.
EP0669396A4 (en) Novel polypeptides and DNA coding for them.
DK0648836T3 (da) MHC-klasse II-transaktivator (CIITA) og anvendelser deraf
ATE116007T1 (de) Gasspülstein.
SE9303475L (sv) Pumphus för virvelströmspump
DE69227661T2 (de) Lineare Plasmide von Pichia pastoris und Fragmente davon
DK130290D0 (da) Lymfokiner, dna-sekvenser, som koder for disse lymfokiner og farmaceutiske midler indeholdende disse lymfokiner
EP0659884A3 (en) Carrot 16kd protein, gene encoding this protein, and plazmid containing this gene.
MX9203684A (es) Benzotiazepinas.
SE9002213D0 (sv) Albumin binding proteins
NO20011961D0 (no) PRV-1-genet og anvendelsen av dette
DK52893D0 (da) Polypeptides, dna coding for the polypeptides, and uses thereof
DK104692D0 (da) A polypeptide, dna coding for the polypeptide, and uses thereof
DK111892D0 (da) A polypeptide, dna coding for the polypeptide, and uses thereof

Legal Events

Date Code Title Description
MK1K Patent expired