DK217889D0 - Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for desacetoxycephalosporin c synthetase - Google Patents

Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for desacetoxycephalosporin c synthetase

Info

Publication number
DK217889D0
DK217889D0 DK217889A DK217889A DK217889D0 DK 217889 D0 DK217889 D0 DK 217889D0 DK 217889 A DK217889 A DK 217889A DK 217889 A DK217889 A DK 217889A DK 217889 D0 DK217889 D0 DK 217889D0
Authority
DK
Denmark
Prior art keywords
desacetoxycephalosporin
synthetase
coding
expression vectors
dna
Prior art date
Application number
DK217889A
Other languages
English (en)
Other versions
DK217889A (da
Inventor
Thomas Dominick Ingolia
Steven Kovacevic
James Robert Miller
Paul Luther Skatrud
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK217889D0 publication Critical patent/DK217889D0/da
Publication of DK217889A publication Critical patent/DK217889A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK217889A 1988-05-09 1989-05-03 Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for desacetoxycephalosporin c synthetase DK217889A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/192,273 US5070020A (en) 1988-05-09 1988-05-09 Recombinant dna expression vectors and dna compounds that encode deacetoxycephalosporin c synthetase

Publications (2)

Publication Number Publication Date
DK217889D0 true DK217889D0 (da) 1989-05-03
DK217889A DK217889A (da) 1989-11-13

Family

ID=22708994

Family Applications (1)

Application Number Title Priority Date Filing Date
DK217889A DK217889A (da) 1988-05-09 1989-05-03 Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for desacetoxycephalosporin c synthetase

Country Status (7)

Country Link
US (1) US5070020A (da)
EP (1) EP0341892A1 (da)
JP (1) JPH0227984A (da)
AU (1) AU622662B2 (da)
DK (1) DK217889A (da)
HU (1) HU209581B (da)
IL (1) IL90129A0 (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3789880T2 (de) * 1986-01-31 1994-09-08 Beecham Group Plc Isolierung und Expression von bei der Biosynthese von Beta-Laktamen beteiligten Genen.
US6709859B1 (en) 1986-01-31 2004-03-23 Beecham Group P.L.C. Chromosomal DNA Fragments Encoding Enzymes for Encoding B-Lactam Biosynthesis Enzymes, and Vector and Transformants for Their Expression
CA2045951A1 (en) * 1990-07-06 1992-01-07 Steven Kovacevic Recombinant dna expression vectors and dna compounds that encode deacetylcephalosporin c synthase activity
US5318896A (en) * 1991-09-11 1994-06-07 Merck & Co., Inc. Recombinant expandase bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid (7-ADCA)
KR100227711B1 (ko) * 1991-10-15 1999-12-01 한스 발터 라벤 7-아미노세팔로스포란산 및 7-아미노데아세틸세팔로스포란산 제조를 위한 신규한 생물학적 공정
US5554507A (en) * 1992-07-30 1996-09-10 American Cyanamid Company Bacillus subtilis siderophore genes
HU219265B (en) * 1993-07-30 2001-03-28 Gist Brocades Bv Process for the efficient production of 7-adca via 3-(carboxyethylthio)propionyl-7-adca, recombinant dna vectors and host cells
CA2188257A1 (en) * 1994-04-22 1995-11-02 Juan Jose R. Coque Dna encoding cephamycin biosynthesis late enzymes
EP0777737B1 (en) * 1994-06-30 2005-05-04 Novozymes Biotech, Inc. Non-toxic, non-toxigenic, non-pathogenic fusarium expression system and promoters and terminators for use therein
CN1084791C (zh) * 1995-06-02 2002-05-15 吉斯特·布罗卡迪斯股份有限公司 通过扩环酶活性作用于青霉素g生产7－adca的方法
US5731165A (en) * 1995-06-02 1998-03-24 Gist-Brocades, B.V. Process for the production of 7-ADCA via expandase activity on penicillin G
WO1997020053A2 (en) * 1995-11-27 1997-06-05 Gist-Brocades B.V. Improved process for the production of semi-synthetic cephalosporins via expandase activity on penicillin g
WO1998002551A2 (en) * 1996-07-16 1998-01-22 Gist-Brocades B.V. Process for the production of adipoyl cephalosporins
US6074847A (en) * 1996-12-13 2000-06-13 Eli Lilly And Company Streptococcus pneumoniae gene sequence HI1146
BR9910532A (pt) 1998-05-19 2001-10-16 Dsm Nv Produção melhorada in vivo de cefalosporina
US6720479B1 (en) * 1998-05-29 2004-04-13 Iowa State University Research Foundation, Inc. Plant retroelements and methods related thereto
US7094953B2 (en) 1998-05-29 2006-08-22 Iowa State University Research Foundation, Inc. Plant retroelements and methods related thereto
US6284483B1 (en) * 1999-10-06 2001-09-04 Board Of Trustees Operating Michigan State University Modified synthetases to produce penicillins and cephalosporins under the control of bicarbonate
WO2003000715A1 (en) * 2001-06-22 2003-01-03 Ceres, Inc. Chimeric histone acetyltransferase polypeptides
WO2003006477A1 (en) 2001-07-12 2003-01-23 University Of Massachusetts IN VIVO PRODUCTION OF SMALL INTERFERING RNAs THAT MEDIATE GENE SILENCING
EP1900815B1 (en) 2001-07-12 2016-09-07 University of Massachusetts In vivo production of small interfering RNAs that mediate gene silencing
US6699699B2 (en) 2002-03-26 2004-03-02 Synmax Biochemical Co., Ltd. Mutated penicillin expandases
US20070093465A1 (en) 2003-05-28 2007-04-26 Van Den Berg Marco A Cephem compound
ATE485394T1 (de) 2003-06-02 2010-11-15 Univ Massachusetts Verfahren und zusammensetzungen zur verbesserung der wirksamkeit und spezifität von fnai
EP3502252B1 (en) 2003-06-02 2023-04-05 University of Massachusetts Methods and compositions for controlling efficacy of rna silencing
WO2007107810A1 (en) * 2006-03-20 2007-09-27 Council Of Scientific And Industrial Research A method for detecting the presence of water born pathogens and indicator microorganism
EP2376619A4 (en) 2008-12-15 2012-07-04 Greenlight Biosciences Inc METHODS FOR CONTROLLING FLOWS IN METABOLIC PATHWAYS
WO2010074760A1 (en) * 2008-12-22 2010-07-01 Greenlight Biosciences Compositions and methods for the production of a compound
EP2566953B1 (en) 2010-05-07 2019-01-02 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through enzyme relocation
JP6280367B2 (ja) 2010-08-31 2018-02-14 グリーンライト バイオサイエンシーズ インコーポレーテッドＧｒｅｅｎｌｉｇｈｔ Ｂｉｏｓｃｉｅｎｃｅｓ，Ｉｎｃ． プロテアーゼ操作を介した代謝経路におけるフラックスの制御のための方法
SG2014014377A (en) 2011-09-09 2014-05-29 Greenlight Biosciences Inc Cell-free preparation of carbapenems
JP6483687B2 (ja) 2013-08-05 2019-03-13 グリーンライト バイオサイエンシーズ インコーポレーテッドＧｒｅｅｎｌｉｇｈｔ Ｂｉｏｓｃｉｅｎｃｅｓ，Ｉｎｃ． プロテアーゼ切断部位を有する操作されたタンパク質
MY193444A (en) 2015-03-30 2022-10-13 Greenlight Biosciences Inc Cell-free production of ribonucleic acid
SG11201808721YA (en) 2016-04-06 2018-11-29 Greenlight Biosciences Inc Cell-free production of ribonucleic acid
AR113764A1 (es) 2017-10-11 2020-06-10 Greenlight Biosciences Inc Métodos y composiciones para la producción de nucleósido trifosfato y ácido ribonucleico

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4510246A (en) * 1982-08-23 1985-04-09 Queen's University At Kingston Isolation of cyclase, epimerase and a ring expansion enzyme for producing unnatural cephalosporins
US4536476A (en) * 1982-08-23 1985-08-20 Queen's University At Kingston Stable epimerase reagent, cyclase reagent and ring expansion reagent for cell-free production of cephalosporins
DE3789880T2 (de) * 1986-01-31 1994-09-08 Beecham Group Plc Isolierung und Expression von bei der Biosynthese von Beta-Laktamen beteiligten Genen.

Also Published As

Publication number Publication date
IL90129A0 (en) 1989-12-15
AU622662B2 (en) 1992-04-16
HUT51672A (en) 1990-05-28
US5070020A (en) 1991-12-03
AU3408289A (en) 1989-11-09
HU209581B (en) 1994-08-29
DK217889A (da) 1989-11-13
EP0341892A1 (en) 1989-11-15
JPH0227984A (ja) 1990-01-30

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