ZA929711B - Novel DNA molecules and hosts. - Google Patents

Novel DNA molecules and hosts.

Info

Publication number
ZA929711B
ZA929711B ZA929711A ZA929711A ZA929711B ZA 929711 B ZA929711 B ZA 929711B ZA 929711 A ZA929711 A ZA 929711A ZA 929711 A ZA929711 A ZA 929711A ZA 929711 B ZA929711 B ZA 929711B
Authority
ZA
South Africa
Prior art keywords
dna molecules
hosts
novel dna
endoplasmic reticulum
dibasic
Prior art date
Application number
ZA929711A
Other languages
English (en)
Inventor
Bhabatosh Chaudhuri
Christine Stephan
Peter Seeboth
Howard Riezman
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of ZA929711B publication Critical patent/ZA929711B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/60—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/04—Fusion polypeptide containing a localisation/targetting motif containing an ER retention signal such as a C-terminal HDEL motif
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Analytical Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
ZA929711A 1991-12-16 1992-12-15 Novel DNA molecules and hosts. ZA929711B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91810984 1991-12-16

Publications (1)

Publication Number Publication Date
ZA929711B true ZA929711B (en) 1993-06-16

Family

ID=8208912

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA929711A ZA929711B (en) 1991-12-16 1992-12-15 Novel DNA molecules and hosts.

Country Status (17)

Country Link
US (2) US5501975A (xx)
EP (1) EP0548012B1 (xx)
JP (1) JP3305781B2 (xx)
KR (1) KR100270283B1 (xx)
AT (1) ATE157703T1 (xx)
AU (1) AU667852B2 (xx)
CA (1) CA2085308C (xx)
DE (1) DE69222013T2 (xx)
DK (1) DK0548012T3 (xx)
ES (1) ES2107520T3 (xx)
FI (1) FI105482B (xx)
GR (1) GR3025324T3 (xx)
IL (1) IL104075A (xx)
MX (1) MX9207291A (xx)
NO (1) NO308619B1 (xx)
NZ (1) NZ245469A (xx)
ZA (1) ZA929711B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9404270D0 (en) * 1994-03-05 1994-04-20 Delta Biotechnology Ltd Yeast strains and modified albumins
US5807702A (en) * 1995-02-27 1998-09-15 Abbott Laboratories Method for expressing phosphorylated recombinant human β-casein in a bacterial system
WO1996027017A1 (en) * 1995-02-27 1996-09-06 Abbott Laboratories A method for expressing modified recombinant proteins in a bacterial system
US5942254A (en) * 1995-02-27 1999-08-24 Abbott Laboratories Phosphorylated recombinant human β-casein expressed in a bacterial system
NZ303621A (en) * 1995-02-27 1999-04-29 Abbott Lab A plasmid contains recombinant proteins such as human beta-casein with an encoded exogenous enzyme such as human kinase capable of phosphorylating recombinant beta-casein in a bacterial system
US5710044A (en) * 1995-02-27 1998-01-20 Abbott Laboratories Plasmid for expressing phosphorylated recombinant proteins in a bacterial system
AT404838B (de) * 1995-11-24 1999-03-25 Immuno Ag Herstellung von proteinen aus pro-proteinen durch fusionsproteine abgeleitet von furin oder furinanalogen
FR2751000B1 (fr) 1996-07-12 1998-10-30 Inst Nat Sante Rech Med Adn specifiques des bacteries de l'espece neisseria meningitidis, leurs procedes d'obtention et leurs applications biologiques
JP4463988B2 (ja) * 1998-11-06 2010-05-19 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト Ｖｉｉ因子の生産方法
JP4092194B2 (ja) 2000-06-30 2008-05-28 フランダース インターユニバーシティ インスティテュート フォア バイオテクノロジー （ヴィーアイビー） ピキアパストリス（ＰｉｃｈｉａＰａｓｔｏｒｉｓ）におけるタンパク質糖鎖修飾
DE10221411B4 (de) * 2002-05-14 2004-07-08 GSF-Forschungszentrum für Umwelt und Gesundheit GmbH Rekombinantes Fowlpox-Virus
US20040117874A1 (en) * 2002-10-15 2004-06-17 Jianjun Yang Methods for accumulating translocated proteins
US7507573B2 (en) 2003-11-14 2009-03-24 Vib, Vzw Modification of protein glycosylation in methylotrophic yeast
WO2006073472A2 (en) * 2004-05-21 2006-07-13 Mo Bio Laboratories, Inc. Kits and processes for removing contaminants from nucleic acids in environmental and biological samples
US20080082338A1 (en) * 2006-09-29 2008-04-03 O'neil Michael P Systems and methods for secure voice identification and medical device interface
US9926570B2 (en) 2013-03-06 2018-03-27 Glaxosmithkline Llc Host cells and methods of use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3685996T2 (de) * 1985-06-11 1993-01-14 Ciba Geigy Ag Hybrid-interferone.
US5391485A (en) * 1985-08-06 1995-02-21 Immunex Corporation DNAs encoding analog GM-CSF molecules displaying resistance to proteases which cleave at adjacent dibasic residues
FI100106B (fi) * 1986-12-05 1997-09-30 Novartis Ag Menetelmä plasminogeenin yksisäikeisen yhdistelmäaktivaattorin valmist amiseksi
JP2643968B2 (ja) * 1988-02-03 1997-08-25 サントリー株式会社 Ｋｅｘ２エンドプロテアーゼ及びその製造方法

Also Published As

Publication number Publication date
AU667852B2 (en) 1996-04-18
AU3007192A (en) 1993-06-17
DK0548012T3 (da) 1998-04-14
ATE157703T1 (de) 1997-09-15
JP3305781B2 (ja) 2002-07-24
US5501975A (en) 1996-03-26
ES2107520T3 (es) 1997-12-01
FI925678A0 (fi) 1992-12-14
EP0548012A1 (en) 1993-06-23
MX9207291A (es) 1993-07-01
KR930013115A (ko) 1993-07-21
JPH06197787A (ja) 1994-07-19
EP0548012B1 (en) 1997-09-03
DE69222013T2 (de) 1998-01-29
CA2085308A1 (en) 1993-06-17
DE69222013D1 (de) 1997-10-09
NO308619B1 (no) 2000-10-02
NO924847L (no) 1993-06-17
NO924847D0 (no) 1992-12-15
NZ245469A (en) 1995-03-28
FI925678A (fi) 1993-06-17
US5618690A (en) 1997-04-08
IL104075A (en) 2003-01-12
GR3025324T3 (en) 1998-02-27
CA2085308C (en) 2003-12-02
FI105482B (fi) 2000-08-31
KR100270283B1 (ko) 2000-11-01
IL104075A0 (en) 1993-05-13

Similar Documents

Publication Publication Date Title
IL104075A0 (en) Novel dna molecules and hosts
AU693289B2 (en) Denatured low-density lipoprotein receptor
IL96309A0 (en) Polypeptides,dna sequences coding therefor and their preparation
EP0644263A3 (en) Delta-9 desaturase and the gene encoding it.
IL117459A0 (en) DNA encoding papillomavirus type 18
EP0574129A3 (en) Bar code printing apparatus.
DE69333249D1 (de) Neue Schimmel-Protease
IL111482A (en) Aspergillus niger aspartic protease
EP0669396A4 (en) Novel polypeptides and DNA coding for them.
AU2717992A (en) Compact bar code scanning arrangement
IL107880A0 (en) A dna molecule coding for an s-type lectin protein and the protein encoded thereby
IE960874L (en) Macif protein, genes coding therefor, expression vectors¹containing said genes, and transformant cells containing¹said protein
EP0637888A3 (en) Code recording apparatus.
CA2084384A1 (en) Dna coding for uricase and process for producing uricase
DE69227661D1 (de) Lineare Plasmide von Pichia pastoris und Fragmente davon
EP0367641A3 (en) Lymphokines, dna sequences encoding these lymphokines and pharmaceutical compositions containing these lymphokines
NZ218148A (en) E.coli expression vector coding for alpha-1-antitrypsin
Akritas Akritas
TW198014B (xx)
DK111892D0 (da) A polypeptide, dna coding for the polypeptide, and uses thereof
DK104692D0 (da) A polypeptide, dna coding for the polypeptide, and uses thereof
DK52893D0 (da) Polypeptides, dna coding for the polypeptides, and uses thereof
IT1234404B (it) Procedimento di produzione di astucci per occhiali con resine poliuretaniche.