NO306763B1 - Farmasöytiske sammensetninger for opplöseliggjöring av tungt opplöselige virkestoffer - Google Patents

Farmasöytiske sammensetninger for opplöseliggjöring av tungt opplöselige virkestoffer

Info

Publication number
NO306763B1
NO306763B1 NO960069A NO960069A NO306763B1 NO 306763 B1 NO306763 B1 NO 306763B1 NO 960069 A NO960069 A NO 960069A NO 960069 A NO960069 A NO 960069A NO 306763 B1 NO306763 B1 NO 306763B1
Authority
NO
Norway
Prior art keywords
active agent
component
solubilization
pharmaceutical compositions
active substances
Prior art date
Application number
NO960069A
Other languages
English (en)
Norwegian (no)
Other versions
NO960069L (no
NO960069D0 (no
Inventor
Ulrich Posanski
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6492300&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO306763(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO960069L publication Critical patent/NO960069L/no
Publication of NO960069D0 publication Critical patent/NO960069D0/no
Publication of NO306763B1 publication Critical patent/NO306763B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO960069A 1993-07-08 1996-01-05 Farmasöytiske sammensetninger for opplöseliggjöring av tungt opplöselige virkestoffer NO306763B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4322826A DE4322826A1 (de) 1993-07-08 1993-07-08 Pharmazeutisches Präparat
PCT/EP1994/002248 WO1995001786A1 (de) 1993-07-08 1994-07-08 Pharmazeutische präparate für schwerlösliche wirkstoffe

Publications (3)

Publication Number Publication Date
NO960069L NO960069L (no) 1996-01-05
NO960069D0 NO960069D0 (no) 1996-01-05
NO306763B1 true NO306763B1 (no) 1999-12-20

Family

ID=6492300

Family Applications (2)

Application Number Title Priority Date Filing Date
NO960062A NO306929B1 (no) 1993-07-08 1996-01-05 Farmasoeytiske preparater for opploeseliggjoering av cyklosporiner
NO960069A NO306763B1 (no) 1993-07-08 1996-01-05 Farmasöytiske sammensetninger for opplöseliggjöring av tungt opplöselige virkestoffer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO960062A NO306929B1 (no) 1993-07-08 1996-01-05 Farmasoeytiske preparater for opploeseliggjoering av cyklosporiner

Country Status (24)

Country Link
EP (3) EP0710104B1 (ja)
JP (4) JPH08512303A (ja)
KR (2) KR100359044B1 (ja)
CN (2) CN1313154C (ja)
AT (3) ATE201985T1 (ja)
AU (2) AU7385094A (ja)
BR (1) BR9407002A (ja)
CA (2) CA2166204C (ja)
CY (2) CY2308B1 (ja)
CZ (1) CZ291401B6 (ja)
DE (6) DE4322826A1 (ja)
DK (3) DK1092429T3 (ja)
ES (3) ES2218046T3 (ja)
FI (2) FI116197B (ja)
GR (1) GR3036571T3 (ja)
HU (2) HU223073B1 (ja)
NO (2) NO306929B1 (ja)
NZ (2) NZ269552A (ja)
PL (1) PL179717B1 (ja)
PT (2) PT710103E (ja)
RU (1) RU2140291C1 (ja)
SI (1) SI1092429T1 (ja)
SK (1) SK280615B6 (ja)
WO (2) WO1995001786A1 (ja)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH686761A5 (de) 1993-05-27 1996-06-28 Sandoz Ag Galenische Formulierungen.
DE4322826A1 (de) * 1993-07-08 1995-01-12 Galenik Labor Freiburg Gmbh Pharmazeutisches Präparat
GB9409778D0 (en) 1994-05-16 1994-07-06 Dumex Ltd As Compositions
US6413536B1 (en) * 1995-06-07 2002-07-02 Southern Biosystems, Inc. High viscosity liquid controlled delivery system and medical or surgical device
US6696413B2 (en) * 1995-06-16 2004-02-24 Hexal Ag Pharmaceutical preparation with cyclosporin A
BE1009856A5 (fr) 1995-07-14 1997-10-07 Sandoz Sa Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule.
GB9514878D0 (en) * 1995-07-20 1995-09-20 Danbiosyst Uk Vitamin E as a solubilizer for drugs contained in lipid vehicles
GB2317562B (en) * 1995-07-20 1999-08-18 Danbiosyst Uk Lipid vehicle drug delivery composition containing vitamin E
US5597582A (en) * 1995-09-12 1997-01-28 Sanofi Oral gel capsule formulation of 1,2,4-benzotriazine oxides
DE19544507B4 (de) * 1995-11-29 2007-11-15 Novartis Ag Cyclosporin enthaltende Präparate
CZ288631B6 (cs) * 1996-01-18 2001-08-15 Galena, A. S. Léčivé přípravky s obsahem cyklosporinu
CZ288739B6 (cs) * 1996-08-01 2001-08-15 Galena, A. S. Cyklosporin obsahující léčivé přípravky
US6458373B1 (en) 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
GB9705813D0 (en) * 1997-03-20 1997-05-07 Smithkline Beecham Plc Novel compositions
CA2284988A1 (en) * 1997-04-11 1998-10-22 Fujisawa Pharmaceutical Co., Ltd. Medicinal composition
US6365180B1 (en) * 1998-01-20 2002-04-02 Glenn A. Meyer Oral liquid compositions
ID25908A (id) * 1998-03-06 2000-11-09 Novartis Ag Prakonsentrat-prakonsentrat emulsi yang mengandung siklosporin atau makrolida
US7030155B2 (en) 1998-06-05 2006-04-18 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
GB2344520A (en) * 1998-12-08 2000-06-14 Phares Pharm Res Nv Pharmaceutical carriers comprising lipids and polymers
AU2878801A (en) * 1999-10-01 2001-05-10 Natco Pharma Limited An improved pharmaceutical composition and a process for its preparation
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
US20020035107A1 (en) 2000-06-20 2002-03-21 Stefan Henke Highly concentrated stable meloxicam solutions
WO2002041892A1 (fr) * 2000-11-24 2002-05-30 Yamanouchi Pharmaceutical Co., Ltd. Liquide hydrosoluble pour medecine interne
DE10161077A1 (de) 2001-12-12 2003-06-18 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion
AU2002231703B2 (en) 2001-12-14 2007-03-29 Jagotec Ag Pharmaceutical formulation comprising cyclosporin and use thereof
KR100533458B1 (ko) 2002-07-20 2005-12-07 대화제약 주식회사 파클리탁셀의 가용화용 조성물 및 그의 제조 방법
GB2391473B (en) * 2002-08-02 2004-07-07 Satishchandra Punambhai Patel Pharmaceutical compositions
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
WO2004069247A1 (en) 2003-02-06 2004-08-19 Cipla Ltd Topical immunotherapy and compositions for use therein
JPWO2004073692A1 (ja) * 2003-02-18 2006-06-01 山下　伸二 難水溶性薬物のハードカプセル剤
PT2279729T (pt) * 2003-07-17 2016-09-22 Banner Life Sciences Llc Preparações de libertação controlada
EP1568369A1 (en) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
TW200616681A (en) * 2004-10-05 2006-06-01 Recordati Ireland Ltd Lercanidipine capsules
GB0425255D0 (en) * 2004-11-16 2004-12-15 Novartis Ag Pharmaceutical composition
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
BRPI0614417A2 (pt) * 2005-07-28 2011-03-29 Reliant Pharmaceuticals Inc composições farmacêuticas compreendendo bloqueadores de canais de cálcio de dihidropiridina e ácidos graxos de Èmega-3 e métodos de tratamento utilizando as mesmas
GB0526419D0 (en) * 2005-12-23 2006-02-08 Cyclacel Ltd Formulation
US8337883B2 (en) 2006-11-03 2012-12-25 Durect Corporation Transdermal delivery systems
EP1952807A1 (en) * 2007-01-24 2008-08-06 LEK Pharmaceuticals D.D. Sirolimus formulation
ITMI20070720A1 (it) * 2007-04-06 2008-10-07 Monteresearch Srl Composizioni orali contenenti tacrolimus in forma amorfa
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
KR20120061081A (ko) * 2009-04-10 2012-06-12 하이얀 치 새로운 노화 방지 물질 및 그 확인 방법
CN102647971B (zh) 2009-10-12 2016-03-16 贝林格尔.英格海姆维特梅迪卡有限公司 用于包含美洛昔康的组合物的容器
WO2011107150A1 (en) 2010-03-03 2011-09-09 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
JP5970224B2 (ja) 2011-07-11 2016-08-17 株式会社日本自動車部品総合研究所 内燃機関用のスパークプラグ
KR20140071913A (ko) * 2012-12-04 2014-06-12 삼성정밀화학 주식회사 식품 조성물 및 이를 포함하는 연질 캡슐
WO2014169078A2 (en) * 2013-04-09 2014-10-16 Boston Biomedical, Inc. Methods for treating cancer
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
WO2016033556A1 (en) 2014-08-28 2016-03-03 Lipocine Inc. BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS
EA036036B1 (ru) * 2014-11-07 2020-09-16 Сигмойд Фарма Лимитед Композиции, содержащие циклоспорин
US20170072058A1 (en) 2014-11-21 2017-03-16 Solipharma Llc Pharmaceutical composition containing tacrolimus and preparation methods thereof
DK3445362T3 (da) 2016-04-20 2021-10-11 Veroscience Llc Sammensætning og fremgangsmåde til behandling af stofskiftesygdomme
JP2020503269A (ja) 2016-11-28 2020-01-30 リポカイン インコーポレーテッド 経口ウンデカン酸テストステロン療法
EP4233913A3 (en) 2017-10-18 2023-10-18 VeroScience LLC Improved bromocriptine formulations
UA128159C2 (uk) * 2018-03-14 2024-04-24 Канді Терап'Ютікс Лімітед Фармацевтичний препарат для капсули з м'якого желатину, який містить подвійний антагоніст рецептора nk-1/nk-3
CN108853044B (zh) * 2018-07-06 2020-11-06 郑州明泽医药科技有限公司 一种硝苯地平缓释片及其制备方法
KR20220140711A (ko) 2020-01-13 2022-10-18 듀렉트 코퍼레이션 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법
WO2022131656A1 (ko) * 2020-12-15 2022-06-23 윤관식 알칼로이드 함유 수용성 유화 조성물
KR102524312B1 (ko) * 2020-12-15 2023-04-21 윤관식 엑디스테로이드 함유 수용성 유화 조성물
KR102583074B1 (ko) * 2021-01-25 2023-09-25 윤관식 천연 폴리페놀 화합물 함유 수용성 유화 조성물
CN113041236B (zh) * 2021-03-23 2023-03-10 广州新济药业科技有限公司 氟比洛芬巴布剂及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1132518A (en) * 1965-02-18 1968-11-06 Richardson Merrell Inc Medicinal composition
IT1090703B (it) * 1976-12-03 1985-06-26 Scherer Ltd R P Perfezionamento nelle composizioni utili quali veicolo per farmaci
GB8903804D0 (en) * 1989-02-20 1989-04-05 Sandoz Ltd Improvements in or relating to organic compounds
GB8630273D0 (en) * 1986-12-18 1987-01-28 Til Medical Ltd Pharmaceutical delivery systems
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
HU212924B (en) * 1989-05-25 1996-12-30 Chiron Corp Adjuvant formulation comprising a submicron oil droplet emulsion
JPH0525037A (ja) * 1991-07-01 1993-02-02 Upjohn Co:The 経口投与酵素感受性腸溶製剤
DE4322826A1 (de) * 1993-07-08 1995-01-12 Galenik Labor Freiburg Gmbh Pharmazeutisches Präparat

Also Published As

Publication number Publication date
JP2011153150A (ja) 2011-08-11
WO1995001785A1 (de) 1995-01-19
CA2166204C (en) 2009-04-14
FI960032A (fi) 1996-02-09
AU689486B2 (en) 1998-04-02
HU9503965D0 (en) 1996-03-28
ES2124420T3 (es) 1999-02-01
SK1996A3 (en) 1997-04-09
PL179717B1 (pl) 2000-10-31
HU9503868D0 (en) 1996-02-28
NO960062D0 (no) 1996-01-05
DE4494850D2 (de) 1996-08-22
NO960069L (no) 1996-01-05
DE4322826A1 (de) 1995-01-12
CN1496743A (zh) 2004-05-19
HU223073B1 (hu) 2004-03-01
CN1128495A (zh) 1996-08-07
CZ291401B6 (cs) 2003-03-12
PT710103E (pt) 2001-11-30
HUT73661A (en) 1996-09-30
WO1995001786A1 (de) 1995-01-19
PL312255A1 (en) 1996-04-01
FI960042A0 (fi) 1996-01-04
CY2308B1 (en) 2003-11-14
HUT73427A (en) 1996-07-29
JP2009138008A (ja) 2009-06-25
CN1313154C (zh) 2007-05-02
DE59409787D1 (de) 2001-07-19
AU7345794A (en) 1995-02-06
ATE172876T1 (de) 1998-11-15
ATE261720T1 (de) 2004-04-15
DE59407239D1 (de) 1998-12-10
KR100386533B1 (ko) 2003-08-21
JPH08512301A (ja) 1996-12-24
RU2140291C1 (ru) 1999-10-27
ATE201985T1 (de) 2001-06-15
BR9407002A (pt) 1996-09-03
FI960032A0 (fi) 1996-01-03
DE59410365D1 (de) 2004-04-22
ES2218046T3 (es) 2004-11-16
CZ4596A3 (en) 1996-04-17
DK0710104T3 (da) 1999-07-19
EP0710104A1 (de) 1996-05-08
FI116197B (fi) 2005-10-14
CY2604B2 (en) 2010-04-28
ES2159564T3 (es) 2001-10-16
FI116714B (fi) 2006-02-15
HU228127B1 (en) 2012-12-28
DK0710103T3 (da) 2001-09-24
CN1121853C (zh) 2003-09-24
CA2164100A1 (en) 1995-01-19
AU7385094A (en) 1995-02-06
NO960069D0 (no) 1996-01-05
EP1092429A1 (de) 2001-04-18
NZ269808A (en) 1996-07-26
EP0710103A1 (de) 1996-05-08
SK280615B6 (sk) 2000-05-16
FI960042A (fi) 1996-01-04
DE4494851D2 (de) 1996-12-19
GR3036571T3 (en) 2001-12-31
EP0710103B1 (de) 2001-06-13
KR100359044B1 (ko) 2003-02-05
PT1092429E (pt) 2004-08-31
NO306929B1 (no) 2000-01-17
NZ269552A (en) 1996-07-26
SI1092429T1 (en) 2004-08-31
DK1092429T3 (da) 2004-07-19
EP0710104B1 (de) 1998-11-04
EP1092429B1 (de) 2004-03-17
NO960062L (no) 1996-01-05
JPH08512303A (ja) 1996-12-24
CA2166204A1 (en) 1995-01-19

Similar Documents

Publication Publication Date Title
NO306763B1 (no) Farmasöytiske sammensetninger for opplöseliggjöring av tungt opplöselige virkestoffer
TR199501321A2 (tr) Farmasötik bilesimler.
ATE265847T1 (de) Selbstemulgierbare formulierung enthaltend lipophile verbindungen
ES2148694T3 (es) Asociacion de fenofibrato y vitamina e y su uso en terapeutica.
NZ512287A (en) Pharmaceutical compositions comprising a lipophilic drug in a propylene glycol ester of a higher fatty acid carrier, where 60% of the ester is a monoester
DK1154759T3 (da) Dispergerbart koncentrat til indgift af cyclosporin
EA200200415A1 (ru) Композиция фармацевтического носителя
KR960033448A (ko) 도코사헥사엔산(dha) 함유 수용액 조성물
KR960033453A (ko) 비타민 e 제제조성물

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees