NO306409B1 - Monohydrat av (E)-2'-deoxy-2'-(fluormethylen)cytidin - Google Patents
Monohydrat av (E)-2'-deoxy-2'-(fluormethylen)cytidinInfo
- Publication number
- NO306409B1 NO306409B1 NO962848A NO962848A NO306409B1 NO 306409 B1 NO306409 B1 NO 306409B1 NO 962848 A NO962848 A NO 962848A NO 962848 A NO962848 A NO 962848A NO 306409 B1 NO306409 B1 NO 306409B1
- Authority
- NO
- Norway
- Prior art keywords
- fluoromethylene
- cytidine
- deoxy
- monohydrate
- neoplastic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17895294A | 1994-01-07 | 1994-01-07 | |
PCT/US1994/014648 WO1995018815A1 (en) | 1994-01-07 | 1994-12-13 | Monohydrate of (e)-2'-deoxy-2'-(fluoromethylene)cytidine |
Publications (3)
Publication Number | Publication Date |
---|---|
NO962848D0 NO962848D0 (no) | 1996-07-05 |
NO962848L NO962848L (no) | 1996-09-06 |
NO306409B1 true NO306409B1 (no) | 1999-11-01 |
Family
ID=22654587
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO962848A NO306409B1 (no) | 1994-01-07 | 1996-07-05 | Monohydrat av (E)-2'-deoxy-2'-(fluormethylen)cytidin |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP0738273B1 (ja) |
JP (1) | JPH09511227A (ja) |
KR (1) | KR100330328B1 (ja) |
CN (1) | CN1043231C (ja) |
AT (1) | ATE186732T1 (ja) |
AU (1) | AU684604B2 (ja) |
CA (1) | CA2179987C (ja) |
DE (1) | DE69421721T2 (ja) |
DK (1) | DK0738273T3 (ja) |
ES (1) | ES2141330T3 (ja) |
FI (1) | FI114396B (ja) |
GR (1) | GR3032614T3 (ja) |
HU (1) | HU217849B (ja) |
IL (1) | IL112242A (ja) |
MX (1) | MX9500363A (ja) |
NO (1) | NO306409B1 (ja) |
NZ (1) | NZ279030A (ja) |
TW (1) | TW397838B (ja) |
WO (1) | WO1995018815A1 (ja) |
ZA (1) | ZA9512B (ja) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1130363C (zh) | 1997-11-12 | 2003-12-10 | 三菱化学株式会社 | 嘌呤衍生物以及含有其作为有效成分的药物 |
ATE254616T1 (de) | 1999-05-11 | 2003-12-15 | Mitsubishi Chem Corp | Dihydrat eines purinderivates, medikamente die dieses als aktiven wirkstoff enthalten und zwischenprodukte zu dessen herstellung |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2002648C (en) * | 1988-11-15 | 2000-02-29 | James R. Mccarthy | 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl cytidine, uridine and guanosine derivatives |
FI95269C (fi) * | 1989-05-15 | 1996-01-10 | Squibb Bristol Myers Co | 2',3'-dideoksi-inosiinimonohydraatin, 2',3'-dideoksi-2',3'-didehydrot ymidiinimonohydraatin ja 2',3'-dideoksi-2'-fluori-inosiinihemihydraatin antiviraalisia, hyvin vesiliukoisia, stabiileja, kiteisiä suoloja |
JPH0615557B2 (ja) * | 1990-02-19 | 1994-03-02 | ヤマサ醤油株式会社 | 2’―デオキシ―2’―メチリデンシチジンの2水和物結晶 |
KR100255258B1 (ko) * | 1992-05-12 | 2000-05-01 | 슈테펜 엘. 네스비트 | 리보뉴클레오티드 환원 효소 억제제의 제조방법 |
-
1994
- 1994-12-13 DE DE69421721T patent/DE69421721T2/de not_active Expired - Fee Related
- 1994-12-13 CA CA002179987A patent/CA2179987C/en not_active Expired - Fee Related
- 1994-12-13 DK DK95907232T patent/DK0738273T3/da active
- 1994-12-13 JP JP7518503A patent/JPH09511227A/ja active Pending
- 1994-12-13 HU HU9601848A patent/HU217849B/hu not_active IP Right Cessation
- 1994-12-13 AU AU15532/95A patent/AU684604B2/en not_active Ceased
- 1994-12-13 ES ES95907232T patent/ES2141330T3/es not_active Expired - Lifetime
- 1994-12-13 EP EP95907232A patent/EP0738273B1/en not_active Expired - Lifetime
- 1994-12-13 CN CN94194779A patent/CN1043231C/zh not_active Expired - Fee Related
- 1994-12-13 KR KR1019960703658A patent/KR100330328B1/ko not_active IP Right Cessation
- 1994-12-13 WO PCT/US1994/014648 patent/WO1995018815A1/en active IP Right Grant
- 1994-12-13 NZ NZ279030A patent/NZ279030A/en unknown
- 1994-12-13 AT AT95907232T patent/ATE186732T1/de not_active IP Right Cessation
-
1995
- 1995-01-03 ZA ZA9512A patent/ZA9512B/xx unknown
- 1995-01-04 IL IL11224295A patent/IL112242A/xx not_active IP Right Cessation
- 1995-01-04 TW TW084100012A patent/TW397838B/zh not_active IP Right Cessation
- 1995-01-06 MX MX9500363A patent/MX9500363A/es unknown
-
1996
- 1996-07-05 NO NO962848A patent/NO306409B1/no unknown
- 1996-07-05 FI FI962769A patent/FI114396B/fi active IP Right Grant
-
2000
- 2000-02-09 GR GR20000400313T patent/GR3032614T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FI114396B (fi) | 2004-10-15 |
EP0738273A1 (en) | 1996-10-23 |
HUT75055A (en) | 1997-03-28 |
NO962848D0 (no) | 1996-07-05 |
IL112242A0 (en) | 1995-03-30 |
EP0738273B1 (en) | 1999-11-17 |
NZ279030A (en) | 1997-05-26 |
ES2141330T3 (es) | 2000-03-16 |
TW397838B (en) | 2000-07-11 |
GR3032614T3 (en) | 2000-05-31 |
CN1141045A (zh) | 1997-01-22 |
CN1043231C (zh) | 1999-05-05 |
WO1995018815A1 (en) | 1995-07-13 |
KR100330328B1 (ko) | 2002-12-05 |
JPH09511227A (ja) | 1997-11-11 |
AU1553295A (en) | 1995-08-01 |
ZA9512B (en) | 1995-09-11 |
MX9500363A (es) | 1998-04-30 |
FI962769A0 (fi) | 1996-07-05 |
CA2179987C (en) | 1999-01-19 |
CA2179987A1 (en) | 1995-07-13 |
FI962769A (fi) | 1996-07-05 |
AU684604B2 (en) | 1997-12-18 |
DK0738273T3 (da) | 2000-04-17 |
HU9601848D0 (en) | 1996-09-30 |
DE69421721T2 (de) | 2000-04-27 |
ATE186732T1 (de) | 1999-12-15 |
HU217849B (hu) | 2000-04-28 |
DE69421721D1 (de) | 1999-12-23 |
IL112242A (en) | 2000-08-31 |
NO962848L (no) | 1996-09-06 |
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