ZA9512B - Monohydrate of (E)-2'-deoxy-2'-(fluoromethylene)cytidine - Google Patents
Monohydrate of (E)-2'-deoxy-2'-(fluoromethylene)cytidineInfo
- Publication number
- ZA9512B ZA9512B ZA9512A ZA9512A ZA9512B ZA 9512 B ZA9512 B ZA 9512B ZA 9512 A ZA9512 A ZA 9512A ZA 9512 A ZA9512 A ZA 9512A ZA 9512 B ZA9512 B ZA 9512B
- Authority
- ZA
- South Africa
- Prior art keywords
- fluoromethylene
- cytidine
- deoxy
- monohydrate
- neoplastic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17895294A | 1994-01-07 | 1994-01-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA9512B true ZA9512B (en) | 1995-09-11 |
Family
ID=22654587
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9512A ZA9512B (en) | 1994-01-07 | 1995-01-03 | Monohydrate of (E)-2'-deoxy-2'-(fluoromethylene)cytidine |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0738273B1 (ja) |
| JP (1) | JPH09511227A (ja) |
| KR (1) | KR100330328B1 (ja) |
| CN (1) | CN1043231C (ja) |
| AT (1) | ATE186732T1 (ja) |
| AU (1) | AU684604B2 (ja) |
| CA (1) | CA2179987C (ja) |
| DE (1) | DE69421721T2 (ja) |
| DK (1) | DK0738273T3 (ja) |
| ES (1) | ES2141330T3 (ja) |
| FI (1) | FI114396B (ja) |
| GR (1) | GR3032614T3 (ja) |
| HU (1) | HU217849B (ja) |
| IL (1) | IL112242A (ja) |
| MX (1) | MX9500363A (ja) |
| NO (1) | NO306409B1 (ja) |
| NZ (1) | NZ279030A (ja) |
| TW (1) | TW397838B (ja) |
| WO (1) | WO1995018815A1 (ja) |
| ZA (1) | ZA9512B (ja) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2309350C (en) | 1997-11-12 | 2007-04-03 | Mitsubishi Chemical Corporation | Purine derivatives and medicaments comprising the same as active ingredient |
| DE60006663T2 (de) | 1999-05-11 | 2004-10-07 | Mitsubishi Chem Corp | Dihydrat eines purinderivates, medikamente die dieses als aktiven wirkstoff enthalten und zwischenprodukte zu dessen herstellung |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2002648C (en) * | 1988-11-15 | 2000-02-29 | James R. Mccarthy | 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl cytidine, uridine and guanosine derivatives |
| FI95269C (fi) * | 1989-05-15 | 1996-01-10 | Squibb Bristol Myers Co | 2',3'-dideoksi-inosiinimonohydraatin, 2',3'-dideoksi-2',3'-didehydrot ymidiinimonohydraatin ja 2',3'-dideoksi-2'-fluori-inosiinihemihydraatin antiviraalisia, hyvin vesiliukoisia, stabiileja, kiteisiä suoloja |
| JPH0615557B2 (ja) * | 1990-02-19 | 1994-03-02 | ヤマサ醤油株式会社 | ２’―デオキシ―２’―メチリデンシチジンの２水和物結晶 |
| EP0640092B1 (en) * | 1992-05-12 | 1996-12-11 | Merrell Pharmaceuticals Inc. | A process for the preparation of ribonucleotide reductase inhibitors |
-
1994
- 1994-12-13 CA CA002179987A patent/CA2179987C/en not_active Expired - Fee Related
- 1994-12-13 AU AU15532/95A patent/AU684604B2/en not_active Ceased
- 1994-12-13 NZ NZ279030A patent/NZ279030A/en unknown
- 1994-12-13 AT AT95907232T patent/ATE186732T1/de not_active IP Right Cessation
- 1994-12-13 WO PCT/US1994/014648 patent/WO1995018815A1/en active IP Right Grant
- 1994-12-13 DK DK95907232T patent/DK0738273T3/da active
- 1994-12-13 ES ES95907232T patent/ES2141330T3/es not_active Expired - Lifetime
- 1994-12-13 DE DE69421721T patent/DE69421721T2/de not_active Expired - Fee Related
- 1994-12-13 CN CN94194779A patent/CN1043231C/zh not_active Expired - Fee Related
- 1994-12-13 EP EP95907232A patent/EP0738273B1/en not_active Expired - Lifetime
- 1994-12-13 HU HU9601848A patent/HU217849B/hu not_active IP Right Cessation
- 1994-12-13 KR KR1019960703658A patent/KR100330328B1/ko not_active IP Right Cessation
- 1994-12-13 JP JP7518503A patent/JPH09511227A/ja active Pending
-
1995
- 1995-01-03 ZA ZA9512A patent/ZA9512B/xx unknown
- 1995-01-04 TW TW084100012A patent/TW397838B/zh not_active IP Right Cessation
- 1995-01-04 IL IL11224295A patent/IL112242A/xx not_active IP Right Cessation
- 1995-01-06 MX MX9500363A patent/MX9500363A/es unknown
-
1996
- 1996-07-05 FI FI962769A patent/FI114396B/fi active IP Right Grant
- 1996-07-05 NO NO962848A patent/NO306409B1/no unknown
-
2000
- 2000-02-09 GR GR20000400313T patent/GR3032614T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0738273A1 (en) | 1996-10-23 |
| NZ279030A (en) | 1997-05-26 |
| ES2141330T3 (es) | 2000-03-16 |
| IL112242A0 (en) | 1995-03-30 |
| NO962848D0 (no) | 1996-07-05 |
| CA2179987A1 (en) | 1995-07-13 |
| FI114396B (fi) | 2004-10-15 |
| EP0738273B1 (en) | 1999-11-17 |
| GR3032614T3 (en) | 2000-05-31 |
| AU684604B2 (en) | 1997-12-18 |
| CA2179987C (en) | 1999-01-19 |
| AU1553295A (en) | 1995-08-01 |
| NO306409B1 (no) | 1999-11-01 |
| CN1141045A (zh) | 1997-01-22 |
| WO1995018815A1 (en) | 1995-07-13 |
| ATE186732T1 (de) | 1999-12-15 |
| TW397838B (en) | 2000-07-11 |
| JPH09511227A (ja) | 1997-11-11 |
| HU217849B (hu) | 2000-04-28 |
| MX9500363A (es) | 1998-04-30 |
| CN1043231C (zh) | 1999-05-05 |
| FI962769A0 (fi) | 1996-07-05 |
| FI962769A (fi) | 1996-07-05 |
| DE69421721T2 (de) | 2000-04-27 |
| HU9601848D0 (en) | 1996-09-30 |
| HUT75055A (en) | 1997-03-28 |
| NO962848L (no) | 1996-09-06 |
| KR100330328B1 (ko) | 2002-12-05 |
| DK0738273T3 (da) | 2000-04-17 |
| DE69421721D1 (de) | 1999-12-23 |
| IL112242A (en) | 2000-08-31 |
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