FI962769A - (E)-2'-deoksi-2'(fluorimetyleeni)sytidiinin monohydraatti - Google Patents
(E)-2'-deoksi-2'(fluorimetyleeni)sytidiinin monohydraatti Download PDFInfo
- Publication number
- FI962769A FI962769A FI962769A FI962769A FI962769A FI 962769 A FI962769 A FI 962769A FI 962769 A FI962769 A FI 962769A FI 962769 A FI962769 A FI 962769A FI 962769 A FI962769 A FI 962769A
- Authority
- FI
- Finland
- Prior art keywords
- fluoromethylene
- cytidinmonohydrat
- deoxi
- cytidine
- deoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17895294A | 1994-01-07 | 1994-01-07 | |
US17895294 | 1994-01-07 | ||
US9414648 | 1994-12-13 | ||
PCT/US1994/014648 WO1995018815A1 (en) | 1994-01-07 | 1994-12-13 | Monohydrate of (e)-2'-deoxy-2'-(fluoromethylene)cytidine |
Publications (3)
Publication Number | Publication Date |
---|---|
FI962769A0 FI962769A0 (fi) | 1996-07-05 |
FI962769A true FI962769A (fi) | 1996-07-05 |
FI114396B FI114396B (fi) | 2004-10-15 |
Family
ID=22654587
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI962769A FI114396B (fi) | 1994-01-07 | 1996-07-05 | Menetelmä (E)-2'-deoksi-2'-(fluorimetyleeni)sytidiininmonohydraatin valmistamiseksi |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP0738273B1 (fi) |
JP (1) | JPH09511227A (fi) |
KR (1) | KR100330328B1 (fi) |
CN (1) | CN1043231C (fi) |
AT (1) | ATE186732T1 (fi) |
AU (1) | AU684604B2 (fi) |
CA (1) | CA2179987C (fi) |
DE (1) | DE69421721T2 (fi) |
DK (1) | DK0738273T3 (fi) |
ES (1) | ES2141330T3 (fi) |
FI (1) | FI114396B (fi) |
GR (1) | GR3032614T3 (fi) |
HU (1) | HU217849B (fi) |
IL (1) | IL112242A (fi) |
MX (1) | MX9500363A (fi) |
NO (1) | NO306409B1 (fi) |
NZ (1) | NZ279030A (fi) |
TW (1) | TW397838B (fi) |
WO (1) | WO1995018815A1 (fi) |
ZA (1) | ZA9512B (fi) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1043324B1 (en) | 1997-11-12 | 2004-06-16 | Mitsubishi Chemical Corporation | Purine derivatives and medicine containing the same as the active ingredient |
KR100747106B1 (ko) | 1999-05-11 | 2007-08-08 | 미쯔비시 가가꾸 가부시끼가이샤 | 퓨린 유도체 이수화물, 이를 유효성분으로 함유하는 의약및 이의 제조 중간체 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2002648C (en) * | 1988-11-15 | 2000-02-29 | James R. Mccarthy | 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl cytidine, uridine and guanosine derivatives |
FI95269C (fi) * | 1989-05-15 | 1996-01-10 | Squibb Bristol Myers Co | 2',3'-dideoksi-inosiinimonohydraatin, 2',3'-dideoksi-2',3'-didehydrot ymidiinimonohydraatin ja 2',3'-dideoksi-2'-fluori-inosiinihemihydraatin antiviraalisia, hyvin vesiliukoisia, stabiileja, kiteisiä suoloja |
JPH0615557B2 (ja) * | 1990-02-19 | 1994-03-02 | ヤマサ醤油株式会社 | 2’―デオキシ―2’―メチリデンシチジンの2水和物結晶 |
JP3265548B2 (ja) * | 1992-05-12 | 2002-03-11 | メレルファーマス−ティカルズ インコーポレイテッド | リボヌクレオチド還元酵素阻害剤の製法 |
-
1994
- 1994-12-13 AT AT95907232T patent/ATE186732T1/de not_active IP Right Cessation
- 1994-12-13 ES ES95907232T patent/ES2141330T3/es not_active Expired - Lifetime
- 1994-12-13 AU AU15532/95A patent/AU684604B2/en not_active Ceased
- 1994-12-13 HU HU9601848A patent/HU217849B/hu not_active IP Right Cessation
- 1994-12-13 WO PCT/US1994/014648 patent/WO1995018815A1/en active IP Right Grant
- 1994-12-13 CA CA002179987A patent/CA2179987C/en not_active Expired - Fee Related
- 1994-12-13 DK DK95907232T patent/DK0738273T3/da active
- 1994-12-13 DE DE69421721T patent/DE69421721T2/de not_active Expired - Fee Related
- 1994-12-13 KR KR1019960703658A patent/KR100330328B1/ko not_active IP Right Cessation
- 1994-12-13 JP JP7518503A patent/JPH09511227A/ja active Pending
- 1994-12-13 EP EP95907232A patent/EP0738273B1/en not_active Expired - Lifetime
- 1994-12-13 NZ NZ279030A patent/NZ279030A/en unknown
- 1994-12-13 CN CN94194779A patent/CN1043231C/zh not_active Expired - Fee Related
-
1995
- 1995-01-03 ZA ZA9512A patent/ZA9512B/xx unknown
- 1995-01-04 IL IL11224295A patent/IL112242A/xx not_active IP Right Cessation
- 1995-01-04 TW TW084100012A patent/TW397838B/zh not_active IP Right Cessation
- 1995-01-06 MX MX9500363A patent/MX9500363A/es unknown
-
1996
- 1996-07-05 FI FI962769A patent/FI114396B/fi active IP Right Grant
- 1996-07-05 NO NO962848A patent/NO306409B1/no unknown
-
2000
- 2000-02-09 GR GR20000400313T patent/GR3032614T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
GR3032614T3 (en) | 2000-05-31 |
TW397838B (en) | 2000-07-11 |
NZ279030A (en) | 1997-05-26 |
DE69421721D1 (de) | 1999-12-23 |
IL112242A (en) | 2000-08-31 |
HUT75055A (en) | 1997-03-28 |
WO1995018815A1 (en) | 1995-07-13 |
CA2179987C (en) | 1999-01-19 |
DE69421721T2 (de) | 2000-04-27 |
AU684604B2 (en) | 1997-12-18 |
NO306409B1 (no) | 1999-11-01 |
IL112242A0 (en) | 1995-03-30 |
FI114396B (fi) | 2004-10-15 |
JPH09511227A (ja) | 1997-11-11 |
NO962848D0 (no) | 1996-07-05 |
HU9601848D0 (en) | 1996-09-30 |
ES2141330T3 (es) | 2000-03-16 |
NO962848L (no) | 1996-09-06 |
CN1043231C (zh) | 1999-05-05 |
FI962769A0 (fi) | 1996-07-05 |
CN1141045A (zh) | 1997-01-22 |
AU1553295A (en) | 1995-08-01 |
ATE186732T1 (de) | 1999-12-15 |
MX9500363A (es) | 1998-04-30 |
HU217849B (hu) | 2000-04-28 |
DK0738273T3 (da) | 2000-04-17 |
EP0738273B1 (en) | 1999-11-17 |
EP0738273A1 (en) | 1996-10-23 |
ZA9512B (en) | 1995-09-11 |
KR100330328B1 (ko) | 2002-12-05 |
CA2179987A1 (en) | 1995-07-13 |
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