FI962769A - (E)-2'deoxi-2'(fluormetylen)cytidinmonohydrat - Google Patents

(E)-2'deoxi-2'(fluormetylen)cytidinmonohydrat Download PDF

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Publication number
FI962769A
FI962769A FI962769A FI962769A FI962769A FI 962769 A FI962769 A FI 962769A FI 962769 A FI962769 A FI 962769A FI 962769 A FI962769 A FI 962769A FI 962769 A FI962769 A FI 962769A
Authority
FI
Finland
Prior art keywords
fluoromethylene
cytidinmonohydrat
deoxi
cytidine
deoxy
Prior art date
Application number
FI962769A
Other languages
English (en)
Finnish (fi)
Other versions
FI962769A0 (sv
FI114396B (sv
Inventor
Richard Eugene Donaldson
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of FI962769A0 publication Critical patent/FI962769A0/sv
Publication of FI962769A publication Critical patent/FI962769A/sv
Application granted granted Critical
Publication of FI114396B publication Critical patent/FI114396B/sv

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI962769A 1994-01-07 1996-07-05 Förfarande för framställning av (E)-2'-deoxi-2'-(fluormetylen)sytidinmonohydrat FI114396B (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US17895294A 1994-01-07 1994-01-07
US17895294 1994-01-07
PCT/US1994/014648 WO1995018815A1 (en) 1994-01-07 1994-12-13 Monohydrate of (e)-2'-deoxy-2'-(fluoromethylene)cytidine
US9414648 1994-12-13

Publications (3)

Publication Number Publication Date
FI962769A0 FI962769A0 (sv) 1996-07-05
FI962769A true FI962769A (sv) 1996-07-05
FI114396B FI114396B (sv) 2004-10-15

Family

ID=22654587

Family Applications (1)

Application Number Title Priority Date Filing Date
FI962769A FI114396B (sv) 1994-01-07 1996-07-05 Förfarande för framställning av (E)-2'-deoxi-2'-(fluormetylen)sytidinmonohydrat

Country Status (20)

Country Link
EP (1) EP0738273B1 (sv)
JP (1) JPH09511227A (sv)
KR (1) KR100330328B1 (sv)
CN (1) CN1043231C (sv)
AT (1) ATE186732T1 (sv)
AU (1) AU684604B2 (sv)
CA (1) CA2179987C (sv)
DE (1) DE69421721T2 (sv)
DK (1) DK0738273T3 (sv)
ES (1) ES2141330T3 (sv)
FI (1) FI114396B (sv)
GR (1) GR3032614T3 (sv)
HU (1) HU217849B (sv)
IL (1) IL112242A (sv)
MX (1) MX9500363A (sv)
NO (1) NO306409B1 (sv)
NZ (1) NZ279030A (sv)
TW (1) TW397838B (sv)
WO (1) WO1995018815A1 (sv)
ZA (1) ZA9512B (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2222614T3 (es) 1997-11-12 2005-02-01 Mitsubishi Chemical Corporation Derivados de purina y medicina que los contiene como ingrediente activo.
DE60006663T2 (de) 1999-05-11 2004-10-07 Mitsubishi Chem Corp Dihydrat eines purinderivates, medikamente die dieses als aktiven wirkstoff enthalten und zwischenprodukte zu dessen herstellung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA898567B (en) * 1988-11-15 1990-08-29 Merrell Dow Pharma Novel 2'-halomethylidene,2'-ethenylidene and 2'-ethynyl cytidine,uridine and guanosine derivatives
FI95269C (sv) * 1989-05-15 1996-01-10 Squibb Bristol Myers Co Antivirala, ytterst vattenlösliga, stabila, kristallina salter av 2',3'-dideoxiinosinmonohydrat, 2',3'-dideoxi-2',3'-didehydrotymidinmonohydrat och 2',3'-dideoxi-2'-fluorinosinhemihydrat
JPH0615557B2 (ja) * 1990-02-19 1994-03-02 ヤマサ醤油株式会社 2’―デオキシ―2’―メチリデンシチジンの2水和物結晶
NZ251886A (en) * 1992-05-12 1996-02-27 Merrell Dow Pharma Ribonucleotide reductase inhibitors and their production

Also Published As

Publication number Publication date
HUT75055A (en) 1997-03-28
AU1553295A (en) 1995-08-01
DK0738273T3 (da) 2000-04-17
NO962848L (no) 1996-09-06
MX9500363A (es) 1998-04-30
EP0738273B1 (en) 1999-11-17
ES2141330T3 (es) 2000-03-16
TW397838B (en) 2000-07-11
DE69421721D1 (de) 1999-12-23
HU217849B (hu) 2000-04-28
FI962769A0 (sv) 1996-07-05
AU684604B2 (en) 1997-12-18
IL112242A (en) 2000-08-31
WO1995018815A1 (en) 1995-07-13
CA2179987C (en) 1999-01-19
CN1141045A (zh) 1997-01-22
NO962848D0 (no) 1996-07-05
HU9601848D0 (en) 1996-09-30
NZ279030A (en) 1997-05-26
JPH09511227A (ja) 1997-11-11
FI114396B (sv) 2004-10-15
IL112242A0 (en) 1995-03-30
ZA9512B (en) 1995-09-11
KR100330328B1 (ko) 2002-12-05
GR3032614T3 (en) 2000-05-31
ATE186732T1 (de) 1999-12-15
NO306409B1 (no) 1999-11-01
CN1043231C (zh) 1999-05-05
EP0738273A1 (en) 1996-10-23
CA2179987A1 (en) 1995-07-13
DE69421721T2 (de) 2000-04-27

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