DK0738273T3 - Monohydrat af (E) - 2' - (fluormethylen) -- cytidin - Google Patents
Monohydrat af (E) - 2' - (fluormethylen) -- cytidinInfo
- Publication number
- DK0738273T3 DK0738273T3 DK95907232T DK95907232T DK0738273T3 DK 0738273 T3 DK0738273 T3 DK 0738273T3 DK 95907232 T DK95907232 T DK 95907232T DK 95907232 T DK95907232 T DK 95907232T DK 0738273 T3 DK0738273 T3 DK 0738273T3
- Authority
- DK
- Denmark
- Prior art keywords
- fluoromethylene
- cytidine
- monohydrate
- deoxy
- neoplastic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17895294A | 1994-01-07 | 1994-01-07 | |
| PCT/US1994/014648 WO1995018815A1 (en) | 1994-01-07 | 1994-12-13 | Monohydrate of (e)-2'-deoxy-2'-(fluoromethylene)cytidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0738273T3 true DK0738273T3 (da) | 2000-04-17 |
Family
ID=22654587
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95907232T DK0738273T3 (da) | 1994-01-07 | 1994-12-13 | Monohydrat af (E) - 2' - (fluormethylen) -- cytidin |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0738273B1 (da) |
| JP (1) | JPH09511227A (da) |
| KR (1) | KR100330328B1 (da) |
| CN (1) | CN1043231C (da) |
| AT (1) | ATE186732T1 (da) |
| AU (1) | AU684604B2 (da) |
| CA (1) | CA2179987C (da) |
| DE (1) | DE69421721T2 (da) |
| DK (1) | DK0738273T3 (da) |
| ES (1) | ES2141330T3 (da) |
| FI (1) | FI114396B (da) |
| GR (1) | GR3032614T3 (da) |
| HU (1) | HU217849B (da) |
| IL (1) | IL112242A (da) |
| MX (1) | MX9500363A (da) |
| NO (1) | NO306409B1 (da) |
| NZ (1) | NZ279030A (da) |
| TW (1) | TW397838B (da) |
| WO (1) | WO1995018815A1 (da) |
| ZA (1) | ZA9512B (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100540046B1 (ko) | 1997-11-12 | 2006-01-10 | 미쓰비시 가가꾸 가부시키가이샤 | 퓨린유도체 및 이를 유효성분으로 함유하는 의약 |
| ES2206227T3 (es) | 1999-05-11 | 2004-05-16 | Mitsubishi Chemical Corporation | Dihidrato de un derivado de purina, farmacos que lo contienen como ingrediente activo, e intermedio en su preparacion. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2002648C (en) * | 1988-11-15 | 2000-02-29 | James R. Mccarthy | 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl cytidine, uridine and guanosine derivatives |
| FI95269C (fi) * | 1989-05-15 | 1996-01-10 | Squibb Bristol Myers Co | 2',3'-dideoksi-inosiinimonohydraatin, 2',3'-dideoksi-2',3'-didehydrot ymidiinimonohydraatin ja 2',3'-dideoksi-2'-fluori-inosiinihemihydraatin antiviraalisia, hyvin vesiliukoisia, stabiileja, kiteisiä suoloja |
| JPH0615557B2 (ja) * | 1990-02-19 | 1994-03-02 | ヤマサ醤油株式会社 | ２’―デオキシ―２’―メチリデンシチジンの２水和物結晶 |
| EP0640092B1 (en) * | 1992-05-12 | 1996-12-11 | Merrell Pharmaceuticals Inc. | A process for the preparation of ribonucleotide reductase inhibitors |
-
1994
- 1994-12-13 DE DE69421721T patent/DE69421721T2/de not_active Expired - Fee Related
- 1994-12-13 NZ NZ279030A patent/NZ279030A/en unknown
- 1994-12-13 ES ES95907232T patent/ES2141330T3/es not_active Expired - Lifetime
- 1994-12-13 DK DK95907232T patent/DK0738273T3/da active
- 1994-12-13 AU AU15532/95A patent/AU684604B2/en not_active Ceased
- 1994-12-13 EP EP95907232A patent/EP0738273B1/en not_active Expired - Lifetime
- 1994-12-13 AT AT95907232T patent/ATE186732T1/de not_active IP Right Cessation
- 1994-12-13 CA CA002179987A patent/CA2179987C/en not_active Expired - Fee Related
- 1994-12-13 CN CN94194779A patent/CN1043231C/zh not_active Expired - Fee Related
- 1994-12-13 WO PCT/US1994/014648 patent/WO1995018815A1/en active IP Right Grant
- 1994-12-13 KR KR1019960703658A patent/KR100330328B1/ko not_active IP Right Cessation
- 1994-12-13 HU HU9601848A patent/HU217849B/hu not_active IP Right Cessation
- 1994-12-13 JP JP7518503A patent/JPH09511227A/ja active Pending
-
1995
- 1995-01-03 ZA ZA9512A patent/ZA9512B/xx unknown
- 1995-01-04 IL IL11224295A patent/IL112242A/xx not_active IP Right Cessation
- 1995-01-04 TW TW084100012A patent/TW397838B/zh not_active IP Right Cessation
- 1995-01-06 MX MX9500363A patent/MX9500363A/es unknown
-
1996
- 1996-07-05 NO NO962848A patent/NO306409B1/no unknown
- 1996-07-05 FI FI962769A patent/FI114396B/fi active IP Right Grant
-
2000
- 2000-02-09 GR GR20000400313T patent/GR3032614T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ279030A (en) | 1997-05-26 |
| HU217849B (hu) | 2000-04-28 |
| AU684604B2 (en) | 1997-12-18 |
| FI962769A (fi) | 1996-07-05 |
| ES2141330T3 (es) | 2000-03-16 |
| FI114396B (fi) | 2004-10-15 |
| CN1141045A (zh) | 1997-01-22 |
| MX9500363A (es) | 1998-04-30 |
| CA2179987C (en) | 1999-01-19 |
| NO306409B1 (no) | 1999-11-01 |
| DE69421721D1 (de) | 1999-12-23 |
| IL112242A (en) | 2000-08-31 |
| HUT75055A (en) | 1997-03-28 |
| AU1553295A (en) | 1995-08-01 |
| WO1995018815A1 (en) | 1995-07-13 |
| ATE186732T1 (de) | 1999-12-15 |
| EP0738273B1 (en) | 1999-11-17 |
| GR3032614T3 (en) | 2000-05-31 |
| DE69421721T2 (de) | 2000-04-27 |
| CA2179987A1 (en) | 1995-07-13 |
| KR100330328B1 (ko) | 2002-12-05 |
| IL112242A0 (en) | 1995-03-30 |
| JPH09511227A (ja) | 1997-11-11 |
| HU9601848D0 (en) | 1996-09-30 |
| EP0738273A1 (en) | 1996-10-23 |
| NO962848D0 (no) | 1996-07-05 |
| ZA9512B (en) | 1995-09-11 |
| FI962769A0 (fi) | 1996-07-05 |
| TW397838B (en) | 2000-07-11 |
| CN1043231C (zh) | 1999-05-05 |
| NO962848L (no) | 1996-09-06 |
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