NO303388B1 - Indolderivater, farmas°ytisk preparat inneholdende dem og mellomprodukter ved fremstilling av dem - Google Patents
Indolderivater, farmas°ytisk preparat inneholdende dem og mellomprodukter ved fremstilling av demInfo
- Publication number
- NO303388B1 NO303388B1 NO943762A NO943762A NO303388B1 NO 303388 B1 NO303388 B1 NO 303388B1 NO 943762 A NO943762 A NO 943762A NO 943762 A NO943762 A NO 943762A NO 303388 B1 NO303388 B1 NO 303388B1
- Authority
- NO
- Norway
- Prior art keywords
- intermediates
- preparation
- pharmaceutical preparations
- preparations containing
- indole derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86473792A | 1992-04-07 | 1992-04-07 | |
PCT/US1993/001967 WO1993020073A1 (en) | 1992-04-07 | 1993-03-10 | Indole derivatives as 5-ht1 agonists |
Publications (3)
Publication Number | Publication Date |
---|---|
NO943762D0 NO943762D0 (no) | 1994-10-06 |
NO943762L NO943762L (no) | 1994-10-06 |
NO303388B1 true NO303388B1 (no) | 1998-07-06 |
Family
ID=25343950
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO943762A NO303388B1 (no) | 1992-04-07 | 1994-10-06 | Indolderivater, farmas°ytisk preparat inneholdende dem og mellomprodukter ved fremstilling av dem |
Country Status (26)
Country | Link |
---|---|
US (7) | US5747501A (no) |
EP (1) | EP0635017A1 (no) |
JP (1) | JP2644088B2 (no) |
KR (1) | KR0179072B1 (no) |
CN (2) | CN1050841C (no) |
AU (1) | AU670579B2 (no) |
BR (1) | BR9306201A (no) |
CA (1) | CA2133413C (no) |
CZ (1) | CZ281763B6 (no) |
EG (1) | EG20226A (no) |
FI (1) | FI931558A (no) |
HR (1) | HRP930752A2 (no) |
HU (1) | HUT64062A (no) |
IL (1) | IL105206A (no) |
MX (1) | MX9302011A (no) |
MY (1) | MY108909A (no) |
NO (1) | NO303388B1 (no) |
NZ (1) | NZ251086A (no) |
PL (1) | PL172405B1 (no) |
RU (1) | RU2101283C1 (no) |
SK (1) | SK280193B6 (no) |
TW (1) | TW341565B (no) |
UA (1) | UA27467C2 (no) |
WO (1) | WO1993020073A1 (no) |
YU (1) | YU48931B (no) |
ZA (1) | ZA932440B (no) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5607951A (en) * | 1990-10-15 | 1997-03-04 | Pfizer Inc | Indole derivatives |
US5559129A (en) * | 1990-10-15 | 1996-09-24 | Pfizer Inc | Indole derivatives |
US5559246A (en) * | 1990-10-15 | 1996-09-24 | Pfizer Inc. | Indole derivatives |
US5578612A (en) * | 1990-10-15 | 1996-11-26 | Pfizer Inc. | Indole derivatives |
US5545644A (en) * | 1990-10-15 | 1996-08-13 | Pfizer Inc. | Indole derivatives |
US5747501A (en) * | 1992-04-07 | 1998-05-05 | Pfizer, Inc. | Indole derivatives |
ES2070087B1 (es) * | 1993-08-13 | 1996-02-16 | Pfizer | Derivados de indol |
DK0716649T3 (da) * | 1993-08-31 | 1999-02-08 | Pfizer | 5-Arylindolderivater |
EP0759918A1 (en) * | 1994-05-19 | 1997-03-05 | MERCK SHARP & DOHME LTD. | Piperazine, piperidine and tetrahydropyridine derivatives of indol-3-ylalkyl as 5-ht1d-alpha agonists |
GB9415575D0 (en) * | 1994-08-02 | 1994-09-21 | Merck Sharp & Dohme | Therapeutic agents |
GB9417310D0 (en) * | 1994-08-27 | 1994-10-19 | Pfizer Ltd | Therapeutic agents |
GB9420529D0 (en) | 1994-10-12 | 1994-11-30 | Pfizer Ltd | Indoles |
GB9423682D0 (en) * | 1994-11-23 | 1995-01-11 | Merck Sharp & Dohme | Therapeutic agents |
CA2207201A1 (en) * | 1994-12-06 | 1996-06-13 | Caroline Henry | Azetidine, pyrrolidine and piperidine derivatives as 5ht1 receptor agonists |
AU707537B2 (en) * | 1995-07-31 | 1999-07-15 | Anthera Pharmaceuticals, Inc. | Pyrrolidine derivatives having phospholipase a2 inhibitory activity |
GB9519558D0 (en) * | 1995-09-26 | 1995-11-29 | Merck Sharp & Dohme | Therapeutic agents |
US6051593A (en) * | 1997-06-20 | 2000-04-18 | Sugen, Inc. | 3-(cycloalkanoheteroarylidenyl)-2- indolinone protein tyrosine kinase inhibitors |
EP1100501A4 (en) * | 1998-06-30 | 2002-12-04 | Lilly Co Eli | PYRROLIDINE AND PYRROLIDINE DERIVATIVES INFLUENTING THE SYSTEMS ASSOCIATED WITH SEROTONIN |
EP1103552A4 (en) * | 1998-08-07 | 2003-01-15 | Takeda Chemical Industries Ltd | BENZOTHIEPINE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE |
US5994352A (en) * | 1998-11-13 | 1999-11-30 | Pfizer Inc. | 5-arylindole derivatives |
US6326388B1 (en) * | 1999-12-21 | 2001-12-04 | Celgene Corporation | Substituted 1,3,4-oxadiazoles and a method of reducing TNF-alpha level |
US7041697B2 (en) * | 2002-09-12 | 2006-05-09 | Wyeth | Antidepressant cycloalkylamine derivatives of 2,3-dihydro-1,4-benzodioxan |
AU2006335110B2 (en) * | 2005-12-30 | 2011-04-14 | Merck Sharp & Dohme Corp. | CETP inhibitors |
EP2346505B1 (en) * | 2008-10-16 | 2014-04-23 | Janssen Pharmaceuticals, Inc. | Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors |
US20100217013A1 (en) * | 2008-12-15 | 2010-08-26 | Wenge Li | Enantioselective process for the preparation of zolmitriptan |
WO2014078568A1 (en) | 2012-11-14 | 2014-05-22 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
JP6947749B2 (ja) * | 2016-04-28 | 2021-10-13 | ジエンス ヘンルイ メデイシンカンパニー リミテッドJiangsu Hengrui Medicine Co.,Ltd. | チロシンキナーゼ阻害剤及びその誘導体を製造する方法 |
IL295374A (en) * | 2020-02-04 | 2022-10-01 | Mindset Pharma Inc | 3-pyrrolidine indole derivatives as serotonergic psychedelics for the treatment of central nervous system disorders |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA795239B (en) * | 1978-10-12 | 1980-11-26 | Glaxo Group Ltd | Heterocyclic compounds |
ZA815541B (en) * | 1980-08-12 | 1983-03-30 | Glaxo Group Ltd | Heterocyclic compounds |
US4689336A (en) * | 1981-01-02 | 1987-08-25 | Pfizer Inc. | Hypoglycemic 5-substituted oxazolidine 2,4-diones |
GB8600397D0 (en) * | 1986-01-08 | 1986-02-12 | Glaxo Group Ltd | Chemical compounds |
FR2601008B1 (fr) * | 1986-07-03 | 1990-03-30 | Sanofi Sa | Procede de synthese stereospecifique de derives de l'indole |
HU203330B (en) * | 1987-06-10 | 1991-07-29 | Pfizer | Process for producing oxazolidin-2-one derivatives and hypoglychemic pharmaceutical compositions containing them |
GB8719167D0 (en) * | 1987-08-13 | 1987-09-23 | Glaxo Group Ltd | Chemical compounds |
GB8724912D0 (en) * | 1987-10-23 | 1987-11-25 | Wellcome Found | Indole derivatives |
GB8819024D0 (en) * | 1988-08-10 | 1988-09-14 | Glaxo Group Ltd | Chemical compounds |
IL96891A0 (en) * | 1990-01-17 | 1992-03-29 | Merck Sharp & Dohme | Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them |
YU48855B (sh) * | 1990-06-07 | 2002-06-19 | The Wellcome Foundation Limited | Heterociklična jedinjenja i njihovi derivati koji su modifikatori dejstva 5-hidroksi-triptamina i postupak njihovog dobijanja |
US5578612A (en) | 1990-10-15 | 1996-11-26 | Pfizer Inc. | Indole derivatives |
US5545644A (en) | 1990-10-15 | 1996-08-13 | Pfizer Inc. | Indole derivatives |
WO1992006973A1 (en) * | 1990-10-15 | 1992-04-30 | Pfizer Inc. | Indole derivatives |
US5559246A (en) | 1990-10-15 | 1996-09-24 | Pfizer Inc. | Indole derivatives |
US5607951A (en) | 1990-10-15 | 1997-03-04 | Pfizer Inc | Indole derivatives |
US5559129A (en) | 1990-10-15 | 1996-09-24 | Pfizer Inc | Indole derivatives |
US5208248A (en) * | 1991-01-11 | 1993-05-04 | Merck Sharpe & Dohme, Ltd. | Indazole-substituted five-membered heteroaromatic compounds |
CZ283018B6 (cs) * | 1991-02-01 | 1997-12-17 | Merck Sharp And Dohme Limited | Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi |
TW263508B (no) * | 1991-02-12 | 1995-11-21 | Pfizer | |
BR9206810A (pt) | 1991-11-25 | 1995-10-31 | Pfizer | Derivados de indol |
EP0545478A1 (en) * | 1991-12-03 | 1993-06-09 | MERCK SHARP & DOHME LTD. | Heterocyclic compounds as tachykinin antagonists |
US5409941A (en) | 1992-02-03 | 1995-04-25 | Pfizer Inc. | 5-heteroyl indole derivatives |
TW288010B (no) | 1992-03-05 | 1996-10-11 | Pfizer | |
US5747501A (en) * | 1992-04-07 | 1998-05-05 | Pfizer, Inc. | Indole derivatives |
AU670270B2 (en) | 1992-04-10 | 1996-07-11 | Pfizer Inc. | Acylaminoindole derivatives as 5-HT1 agonists |
-
1993
- 1993-03-10 US US08/295,798 patent/US5747501A/en not_active Expired - Fee Related
- 1993-03-10 WO PCT/US1993/001967 patent/WO1993020073A1/en not_active Application Discontinuation
- 1993-03-10 RU RU94045897/04A patent/RU2101283C1/ru not_active IP Right Cessation
- 1993-03-10 UA UA94105899A patent/UA27467C2/uk unknown
- 1993-03-10 JP JP5517443A patent/JP2644088B2/ja not_active Expired - Fee Related
- 1993-03-10 NZ NZ251086A patent/NZ251086A/en unknown
- 1993-03-10 PL PL93305555A patent/PL172405B1/pl not_active IP Right Cessation
- 1993-03-10 SK SK1206-94A patent/SK280193B6/sk unknown
- 1993-03-10 AU AU37898/93A patent/AU670579B2/en not_active Ceased
- 1993-03-10 EP EP93907216A patent/EP0635017A1/en not_active Ceased
- 1993-03-10 CZ CZ942464A patent/CZ281763B6/cs not_active IP Right Cessation
- 1993-03-10 CA CA002133413A patent/CA2133413C/en not_active Expired - Fee Related
- 1993-03-10 BR BR9306201A patent/BR9306201A/pt not_active Application Discontinuation
- 1993-03-10 KR KR1019940703552A patent/KR0179072B1/ko not_active IP Right Cessation
- 1993-03-29 IL IL10520693A patent/IL105206A/en not_active IP Right Cessation
- 1993-04-02 HR HR930752A patent/HRP930752A2/hr not_active Application Discontinuation
- 1993-04-05 MY MYPI93000616A patent/MY108909A/en unknown
- 1993-04-05 EG EG20593A patent/EG20226A/xx active
- 1993-04-05 ZA ZA932440A patent/ZA932440B/xx unknown
- 1993-04-06 HU HU9301003A patent/HUT64062A/hu unknown
- 1993-04-06 YU YU23893A patent/YU48931B/sh unknown
- 1993-04-06 CN CN93105697A patent/CN1050841C/zh not_active Expired - Fee Related
- 1993-04-06 FI FI931558A patent/FI931558A/fi not_active IP Right Cessation
- 1993-04-06 MX MX9302011A patent/MX9302011A/es unknown
- 1993-04-09 TW TW082102651A patent/TW341565B/zh active
-
1994
- 1994-10-06 NO NO943762A patent/NO303388B1/no not_active IP Right Cessation
-
1998
- 1998-04-14 US US09/059,799 patent/US6150388A/en not_active Expired - Fee Related
- 1998-07-08 CN CN98116024A patent/CN1083443C/zh not_active Expired - Fee Related
-
2000
- 2000-10-23 US US09/694,387 patent/US6436957B1/en not_active Expired - Fee Related
- 2000-10-23 US US09/694,588 patent/US6465500B1/en not_active Expired - Fee Related
- 2000-10-23 US US09/694,394 patent/US6387937B1/en not_active Expired - Fee Related
- 2000-10-23 US US09/694,808 patent/US6410739B1/en not_active Expired - Fee Related
- 2000-10-23 US US09/694,809 patent/US6387941B1/en not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |