NO302686B1 - Osmotisk pumpe - Google Patents
Osmotisk pumpe Download PDFInfo
- Publication number
- NO302686B1 NO302686B1 NO914990A NO914990A NO302686B1 NO 302686 B1 NO302686 B1 NO 302686B1 NO 914990 A NO914990 A NO 914990A NO 914990 A NO914990 A NO 914990A NO 302686 B1 NO302686 B1 NO 302686B1
- Authority
- NO
- Norway
- Prior art keywords
- osmotic
- chamber
- fluid
- piston
- delivery
- Prior art date
Links
- 230000003204 osmotic effect Effects 0.000 title claims description 170
- 239000012530 fluid Substances 0.000 claims description 127
- 239000012528 membrane Substances 0.000 claims description 54
- 150000003839 salts Chemical class 0.000 claims description 49
- 230000004888 barrier function Effects 0.000 claims description 33
- 238000003860 storage Methods 0.000 claims description 33
- 239000011888 foil Substances 0.000 claims description 7
- 238000004891 communication Methods 0.000 claims description 4
- 235000002639 sodium chloride Nutrition 0.000 description 45
- 239000003795 chemical substances by application Substances 0.000 description 37
- 239000000243 solution Substances 0.000 description 12
- 239000007924 injection Substances 0.000 description 10
- 238000002347 injection Methods 0.000 description 10
- 239000007788 liquid Substances 0.000 description 9
- 230000004913 activation Effects 0.000 description 8
- 239000003814 drug Substances 0.000 description 8
- 239000008177 pharmaceutical agent Substances 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- 238000000926 separation method Methods 0.000 description 7
- 230000003213 activating effect Effects 0.000 description 6
- 230000007246 mechanism Effects 0.000 description 6
- 230000008878 coupling Effects 0.000 description 5
- 238000010168 coupling process Methods 0.000 description 5
- 238000005859 coupling reaction Methods 0.000 description 5
- 230000007423 decrease Effects 0.000 description 5
- 229940079593 drug Drugs 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 239000004033 plastic Substances 0.000 description 5
- 229920003023 plastic Polymers 0.000 description 5
- 230000002779 inactivation Effects 0.000 description 4
- 238000005192 partition Methods 0.000 description 4
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 3
- 229910052782 aluminium Inorganic materials 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 238000012377 drug delivery Methods 0.000 description 3
- 108090000765 processed proteins & peptides Proteins 0.000 description 3
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 239000012510 hollow fiber Substances 0.000 description 2
- 238000001990 intravenous administration Methods 0.000 description 2
- 239000008176 lyophilized powder Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 description 1
- 241000220317 Rosa Species 0.000 description 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 229940035676 analgesics Drugs 0.000 description 1
- 239000000730 antalgic agent Substances 0.000 description 1
- 239000000729 antidote Substances 0.000 description 1
- 229940075522 antidotes Drugs 0.000 description 1
- 238000007664 blowing Methods 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- MTAZNLWOLGHBHU-UHFFFAOYSA-N butadiene-styrene rubber Chemical compound C=CC=C.C=CC1=CC=CC=C1 MTAZNLWOLGHBHU-UHFFFAOYSA-N 0.000 description 1
- 229920005549 butyl rubber Polymers 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 229920006217 cellulose acetate butyrate Polymers 0.000 description 1
- 229920001727 cellulose butyrate Polymers 0.000 description 1
- 229920003086 cellulose ether Polymers 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 230000009849 deactivation Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 229920001903 high density polyethylene Polymers 0.000 description 1
- 239000004700 high-density polyethylene Substances 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 239000002502 liposome Substances 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229920001179 medium density polyethylene Polymers 0.000 description 1
- 239000004701 medium-density polyethylene Substances 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000003094 microcapsule Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920001195 polyisoprene Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 230000009291 secondary effect Effects 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- -1 such as in dry Substances 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M2005/14513—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons with secondary fluid driving or regulating the infusion
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Details Of Reciprocating Pumps (AREA)
- Reciprocating Pumps (AREA)
- External Artificial Organs (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909027422A GB9027422D0 (en) | 1990-12-18 | 1990-12-18 | Osmotically driven infusion device |
Publications (3)
Publication Number | Publication Date |
---|---|
NO914990D0 NO914990D0 (no) | 1991-12-17 |
NO914990L NO914990L (no) | 1992-06-19 |
NO302686B1 true NO302686B1 (no) | 1998-04-14 |
Family
ID=10687181
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO914990A NO302686B1 (no) | 1990-12-18 | 1991-12-17 | Osmotisk pumpe |
Country Status (33)
Country | Link |
---|---|
US (1) | US5279608A (pt) |
JP (1) | JP3058738B2 (pt) |
KR (1) | KR920011529A (pt) |
AR (1) | AR244091A1 (pt) |
AT (1) | AT403884B (pt) |
AU (1) | AU652199B2 (pt) |
BE (1) | BE1004788A4 (pt) |
CA (1) | CA2057817A1 (pt) |
CH (1) | CH686871A5 (pt) |
CZ (1) | CZ282437B6 (pt) |
DE (1) | DE4141819B4 (pt) |
DK (1) | DK174860B1 (pt) |
DZ (1) | DZ1548A1 (pt) |
ES (1) | ES2055649B1 (pt) |
FI (1) | FI107434B (pt) |
FR (1) | FR2670387B1 (pt) |
GB (1) | GB9027422D0 (pt) |
GR (1) | GR1001122B (pt) |
HK (1) | HK111895A (pt) |
IE (1) | IE67181B1 (pt) |
IT (1) | IT1252243B (pt) |
LU (1) | LU88040A1 (pt) |
MA (1) | MA22368A1 (pt) |
MY (1) | MY131056A (pt) |
NL (1) | NL194432C (pt) |
NO (1) | NO302686B1 (pt) |
NZ (1) | NZ240824A (pt) |
OA (1) | OA09413A (pt) |
PT (1) | PT99828B (pt) |
RU (1) | RU2098141C1 (pt) |
SE (1) | SE503662C2 (pt) |
TN (1) | TNSN91121A1 (pt) |
ZA (1) | ZA919342B (pt) |
Families Citing this family (122)
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US6132420A (en) * | 1996-02-02 | 2000-10-17 | Alza Corporation | Osmotic delivery system and method for enhancing start-up and performance of osmotic delivery systems |
US6395292B2 (en) * | 1996-02-02 | 2002-05-28 | Alza Corporation | Sustained delivery of an active agent using an implantable system |
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US6331311B1 (en) * | 1996-12-20 | 2001-12-18 | Alza Corporation | Injectable depot gel composition and method of preparing the composition |
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US6610042B2 (en) | 1997-12-05 | 2003-08-26 | Felton Medical, Inc. | Disposable unit-dose jet-injection syringe for pre-filled and/or transfilled liquid injectable medical drug or vaccine products and method thereof |
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US7074210B2 (en) * | 1999-10-11 | 2006-07-11 | Felton International, Inc. | Universal protector cap with auto-disable features for needle-free injectors |
US6770054B1 (en) | 1999-11-23 | 2004-08-03 | Felton International, Inc. | Injector assembly with driving means and locking means |
US7887506B1 (en) | 1999-11-23 | 2011-02-15 | Pulse Needlefree Systems, Inc. | Safety mechanism to prevent accidental patient injection and methods of same |
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DK1409044T3 (da) * | 2001-07-16 | 2008-01-02 | Lilly Co Eli | Injektionsapparat uden patron til flerfoldige doser |
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US9447781B2 (en) * | 2005-07-22 | 2016-09-20 | University Of Utah Research Foundation | Osmotically driven dispense pump and related components for use in high pressure applications |
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-
1991
- 1991-11-22 NL NL9101964A patent/NL194432C/nl not_active IP Right Cessation
- 1991-11-26 ZA ZA919342A patent/ZA919342B/xx unknown
- 1991-11-27 GR GR910100481A patent/GR1001122B/el not_active IP Right Cessation
- 1991-11-29 AR AR91321277A patent/AR244091A1/es active
- 1991-12-02 NZ NZ240824A patent/NZ240824A/en unknown
- 1991-12-03 CH CH03552/91A patent/CH686871A5/fr not_active IP Right Cessation
- 1991-12-04 US US07/802,326 patent/US5279608A/en not_active Expired - Fee Related
- 1991-12-10 IT ITMI913307A patent/IT1252243B/it active IP Right Grant
- 1991-12-10 BE BE9101123A patent/BE1004788A4/fr not_active IP Right Cessation
- 1991-12-11 MY MYPI91002293A patent/MY131056A/en unknown
- 1991-12-12 LU LU88040A patent/LU88040A1/fr unknown
- 1991-12-16 SE SE9103717A patent/SE503662C2/sv not_active IP Right Cessation
- 1991-12-16 AT AT0248891A patent/AT403884B/de not_active IP Right Cessation
- 1991-12-16 FI FI915904A patent/FI107434B/fi not_active IP Right Cessation
- 1991-12-16 MA MA22652A patent/MA22368A1/fr unknown
- 1991-12-17 KR KR1019910023193A patent/KR920011529A/ko not_active Application Discontinuation
- 1991-12-17 PT PT99828A patent/PT99828B/pt not_active IP Right Cessation
- 1991-12-17 CA CA002057817A patent/CA2057817A1/en not_active Abandoned
- 1991-12-17 NO NO914990A patent/NO302686B1/no unknown
- 1991-12-17 DZ DZ910168A patent/DZ1548A1/fr active
- 1991-12-17 IE IE438591A patent/IE67181B1/en not_active IP Right Cessation
- 1991-12-17 ES ES09102800A patent/ES2055649B1/es not_active Expired - Fee Related
- 1991-12-17 RU SU915010426A patent/RU2098141C1/ru not_active IP Right Cessation
- 1991-12-17 AU AU89727/91A patent/AU652199B2/en not_active Ceased
- 1991-12-17 DK DK199102019A patent/DK174860B1/da not_active IP Right Cessation
- 1991-12-18 DE DE4141819A patent/DE4141819B4/de not_active Expired - Fee Related
- 1991-12-18 TN TNTNSN91121A patent/TNSN91121A1/fr unknown
- 1991-12-18 CZ CS913877A patent/CZ282437B6/cs not_active IP Right Cessation
- 1991-12-18 JP JP3334996A patent/JP3058738B2/ja not_active Expired - Fee Related
- 1991-12-18 FR FR9115698A patent/FR2670387B1/fr not_active Expired - Fee Related
- 1991-12-18 OA OA60116A patent/OA09413A/xx unknown
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1995
- 1995-07-06 HK HK111895A patent/HK111895A/xx not_active IP Right Cessation
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