NO300843B1 - Aryliden-l-azacykloalkaner og arylalkyl-l-azacykloalkaner, salter av disse, og legemidler som inneholder disse forbindelser - Google Patents

Aryliden-l-azacykloalkaner og arylalkyl-l-azacykloalkaner, salter av disse, og legemidler som inneholder disse forbindelser Download PDF

Info

Publication number
NO300843B1
NO300843B1 NO933790A NO933790A NO300843B1 NO 300843 B1 NO300843 B1 NO 300843B1 NO 933790 A NO933790 A NO 933790A NO 933790 A NO933790 A NO 933790A NO 300843 B1 NO300843 B1 NO 300843B1
Authority
NO
Norway
Prior art keywords
group
piperidine
benzylidene
oxazolin
hydrogen atom
Prior art date
Application number
NO933790A
Other languages
English (en)
Norwegian (no)
Other versions
NO933790D0 (no
NO933790L (no
Inventor
Roland Maier
Peter Mueller
Eberhard Woitun
Rudolf Hurnaus
Michael Mark
Bernhard Eisele
Ralph-Michael Budzinski
Gerhard Hallermayer
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4235590A external-priority patent/DE4235590A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO933790D0 publication Critical patent/NO933790D0/no
Publication of NO933790L publication Critical patent/NO933790L/no
Publication of NO300843B1 publication Critical patent/NO300843B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Catalysts (AREA)
  • Ink Jet (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO933790A 1992-10-22 1993-10-21 Aryliden-l-azacykloalkaner og arylalkyl-l-azacykloalkaner, salter av disse, og legemidler som inneholder disse forbindelser NO300843B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4235590A DE4235590A1 (de) 1992-10-22 1992-10-22 Aryliden-l-azacycloalkane, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
DE4303840A DE4303840A1 (de) 1992-10-22 1993-02-10 Aryliden-1-azacycloalkane und Arylalkyl-1-azacycloalkane, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung

Publications (3)

Publication Number Publication Date
NO933790D0 NO933790D0 (no) 1993-10-21
NO933790L NO933790L (no) 1994-04-25
NO300843B1 true NO300843B1 (no) 1997-08-04

Family

ID=25919689

Family Applications (1)

Application Number Title Priority Date Filing Date
NO933790A NO300843B1 (no) 1992-10-22 1993-10-21 Aryliden-l-azacykloalkaner og arylalkyl-l-azacykloalkaner, salter av disse, og legemidler som inneholder disse forbindelser

Country Status (21)

Country Link
EP (1) EP0596326B1 (sk)
JP (1) JP3396517B2 (sk)
KR (1) KR100306520B1 (sk)
CN (1) CN1040873C (sk)
AT (1) ATE126797T1 (sk)
AU (1) AU665648B2 (sk)
CA (1) CA2108817C (sk)
CZ (1) CZ286025B6 (sk)
DE (2) DE4303840A1 (sk)
DK (1) DK0596326T3 (sk)
ES (1) ES2078787T3 (sk)
FI (1) FI934665A (sk)
GR (1) GR3017692T3 (sk)
HK (1) HK1000285A1 (sk)
HU (1) HU221630B1 (sk)
IL (1) IL107342A (sk)
NO (1) NO300843B1 (sk)
NZ (1) NZ250018A (sk)
PL (1) PL173775B1 (sk)
RU (1) RU2126400C1 (sk)
SK (1) SK281222B6 (sk)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4234295A1 (de) * 1992-10-12 1994-04-14 Thomae Gmbh Dr K Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
IL110943A (en) * 1994-09-13 1997-02-18 Univ Ramot Compositions comprising an inhibitor of cholesterol synthesis for the treatment of skin disorders
DE19754795A1 (de) * 1997-12-10 1999-06-17 Boehringer Ingelheim Pharma Neue Urethane, ihre Thio- und Dithioanaloga, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
US6228868B1 (en) 1998-07-27 2001-05-08 Abbott Laboratories Oxazoline antiproliferative agents
WO2000006556A1 (en) * 1998-07-27 2000-02-10 Abbott Laboratories Substituted oxazolines as antiproliferative agents
US7667053B2 (en) 2002-04-12 2010-02-23 Merck & Co., Inc. Bicyclic amides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4863932A (en) * 1988-03-11 1989-09-05 Somatogenetics International, Inc. Squalene oxide cyclase inhibitors and therapeutic use thereof
CA2025490C (en) * 1989-09-22 2003-09-16 James R. Mccarthy Novel substituted alkyl piperidines and their use as inhibitors of cholesterol synthesis
CA2047375C (en) * 1990-07-25 2003-04-15 Charlotte L. Barney Piperidyl ethers and thioethers as inhibitors of cholesterol biosynthesis
US5084461A (en) * 1991-03-27 1992-01-28 Merrell Dow Pharmaceuticals Inc. Azadecalin amides and thioamides as inhibitors of cholesterol biosynthesis

Also Published As

Publication number Publication date
AU665648B2 (en) 1996-01-11
CZ286025B6 (cs) 1999-12-15
FI934665A0 (fi) 1993-10-22
EP0596326A1 (de) 1994-05-11
ES2078787T3 (es) 1995-12-16
IL107342A0 (en) 1994-01-25
NO933790D0 (no) 1993-10-21
EP0596326B1 (de) 1995-08-23
NO933790L (no) 1994-04-25
IL107342A (en) 1997-07-13
ATE126797T1 (de) 1995-09-15
CN1090849A (zh) 1994-08-17
SK281222B6 (sk) 2001-01-18
PL300834A1 (en) 1994-05-16
DE4303840A1 (de) 1994-08-11
HK1000285A1 (en) 1998-02-20
FI934665A (fi) 1994-04-23
JP3396517B2 (ja) 2003-04-14
CA2108817C (en) 2004-12-07
PL173775B1 (pl) 1998-04-30
JPH06192256A (ja) 1994-07-12
SK107393A3 (en) 1994-09-07
HU221630B1 (hu) 2002-12-28
AU4913593A (en) 1994-05-05
GR3017692T3 (en) 1996-01-31
CZ223693A3 (en) 1994-05-18
CN1040873C (zh) 1998-11-25
KR100306520B1 (ko) 2001-11-30
RU2126400C1 (ru) 1999-02-20
HUT68958A (en) 1995-08-28
CA2108817A1 (en) 1994-04-23
DK0596326T3 (da) 1996-01-15
KR940009181A (ko) 1994-05-20
NZ250018A (en) 1995-07-26
DE59300507D1 (de) 1995-09-28
HU9302986D0 (en) 1994-01-28

Similar Documents

Publication Publication Date Title
DE602004006431T2 (de) Derivate von n-äheteroaryl(piperidin-2-yl)methylübenzamid, verfahren zu deren herstellung und deren anwendung in therapeutika
AU617139B2 (en) New phenylethanolamines
EP1690858B1 (en) Monohydrochloride salt of 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-piperidine
CN103068800B (zh) 作为趋化因子受体活性调节剂的哌啶基化合物
CN100516040C (zh) 具有2,6-二取代苯乙烯基的含氮杂环衍生物
US4935419A (en) Novel 1-piperazinecarboxamide derivatives
NO300843B1 (no) Aryliden-l-azacykloalkaner og arylalkyl-l-azacykloalkaner, salter av disse, og legemidler som inneholder disse forbindelser
US5466687A (en) Arylidene-1-azacycloalkanes and arylalkyl-1-azacyclo-alkanes, their salts, medicaments containing these compounds and their use, and processes for their preparation
US5726205A (en) O-acyl-4-phenyl-cyclohexanols, their salts, medicaments containing such compounds and their use, as well as a method of preparing them
EP1060162B1 (de) Von azacycloalkanen abgeleitete urethane, ihre thio- und dithioanaloga, deren herstellung und deren verwendung als 2,3-epoxisqualen-lanosterol-cyclase inhibitoren
JP4001317B2 (ja) 新規ウレタン、それらのチオ類似体及びジチオ類似体、これらの塩、これらの化合物を含む医薬組成物並びにそれらの使用及びそれらの調製方法
DE4407138A1 (de) Aryliden-1-azacycloalkane und Arylalkyl-1-azacycloalkane, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
DE4407139A1 (de) Aryl-1-azacycloalkane und deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
DE4235590A1 (de) Aryliden-l-azacycloalkane, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
DE4438083A1 (de) Basisch substituierte Acylpyrrolidine und Acylpiperidine, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
DE4412691A1 (de) Heteroaryliden-1-azacycloalkane und Heteroarylalkyl-1-azacycloalkane, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
DE4407135A1 (de) Arylcycloalkylamine, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
DE19806713A1 (de) Neue Urethane, ihre Thio- und Dithioanaloga, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
CZ20002149A3 (cs) Od azacykloalkanů odvozené urethany a jejich thio- a dithioanaloga
NZ227196A (en) Phenylethanolamine derivatives and their pharmaceutical and veterinary compositions
DE19806714A1 (de) Neue Thio- und Dithiocarbonate, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
CA2188784A1 (en) O-acyl-4-phenyl-cycloalkanols, their salts, medicaments containing such compounds, and their use, as well as a method of preparing them
DE19806717A1 (de) Neue Urethane, ihre Thio- und Dithioanaloga, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
WO1996031483A1 (en) Novel heterocyclic compounds
DE19806715A1 (de) Neue Urethane, ihre Thio- und Dithioanaloga, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees