NO300592B1 - Imidazopyridin PAF/H1 antagonister - Google Patents

Imidazopyridin PAF/H1 antagonister Download PDF

Info

Publication number
NO300592B1
NO300592B1 NO932889A NO932889A NO300592B1 NO 300592 B1 NO300592 B1 NO 300592B1 NO 932889 A NO932889 A NO 932889A NO 932889 A NO932889 A NO 932889A NO 300592 B1 NO300592 B1 NO 300592B1
Authority
NO
Norway
Prior art keywords
pyrid
methylimidazo
ylidene
piperidine
dihydro
Prior art date
Application number
NO932889A
Other languages
English (en)
Norwegian (no)
Other versions
NO932889L (no
NO932889D0 (no
Inventor
David Alker
Robert John Bass
Kelvin Cooper
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO932889L publication Critical patent/NO932889L/no
Publication of NO932889D0 publication Critical patent/NO932889D0/no
Publication of NO300592B1 publication Critical patent/NO300592B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Prostheses (AREA)
  • Steroid Compounds (AREA)
NO932889A 1991-02-13 1993-08-13 Imidazopyridin PAF/H1 antagonister NO300592B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919102997A GB9102997D0 (en) 1991-02-13 1991-02-13 Therapeutic agents
PCT/EP1992/000163 WO1992014734A1 (en) 1991-02-13 1992-01-24 Imidazopyridine paf/h1 antagonists

Publications (3)

Publication Number Publication Date
NO932889L NO932889L (no) 1993-08-13
NO932889D0 NO932889D0 (no) 1993-08-13
NO300592B1 true NO300592B1 (no) 1997-06-23

Family

ID=10689943

Family Applications (1)

Application Number Title Priority Date Filing Date
NO932889A NO300592B1 (no) 1991-02-13 1993-08-13 Imidazopyridin PAF/H1 antagonister

Country Status (29)

Country Link
US (1) US5358953A (Sortimente)
EP (1) EP0572425B1 (Sortimente)
JP (1) JP2506541B2 (Sortimente)
KR (1) KR970005302B1 (Sortimente)
CN (1) CN1040326C (Sortimente)
AT (1) ATE109482T1 (Sortimente)
AU (1) AU650322B2 (Sortimente)
BR (1) BR9205615A (Sortimente)
CA (1) CA2099381C (Sortimente)
CZ (1) CZ280504B6 (Sortimente)
DE (1) DE69200304T2 (Sortimente)
DK (1) DK0572425T3 (Sortimente)
EG (1) EG20085A (Sortimente)
ES (1) ES2059212T3 (Sortimente)
FI (1) FI933531L (Sortimente)
GB (1) GB9102997D0 (Sortimente)
HU (2) HUT65947A (Sortimente)
IE (1) IE65125B1 (Sortimente)
IL (1) IL100887A (Sortimente)
MX (1) MX9200589A (Sortimente)
MY (1) MY108437A (Sortimente)
NO (1) NO300592B1 (Sortimente)
NZ (1) NZ241597A (Sortimente)
PL (1) PL169304B1 (Sortimente)
RU (1) RU2114845C1 (Sortimente)
TW (1) TW227000B (Sortimente)
WO (1) WO1992014734A1 (Sortimente)
YU (1) YU48238B (Sortimente)
ZA (1) ZA921005B (Sortimente)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2042421B1 (es) * 1992-05-22 1994-08-01 Uriach & Cia Sa J Procedimiento para la obtencion de la 8-cloro-11-*1-*(5-metil-3-piridil)metil*-4-piperidiliden*-6,11-dihidro-5h-benzo*5,6*ciclohepta*1,2-b*piridina.
AU3186395A (en) * 1994-08-10 1996-03-07 British Biotech Pharmaceuticals Limited Imidazopyridine derivatives as dual histamine (h1) and platelet activating factor (paf) antagonists
ES2087038B1 (es) * 1994-11-07 1997-03-16 Uriach & Cia Sa J Nuevas piperidinas con actividad antagonista del paf.
US5567711A (en) * 1995-04-19 1996-10-22 Abbott Laboratories Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists
GB9508748D0 (en) * 1995-04-28 1995-06-14 British Biotech Pharm Benzimidazole derivatives
SK12798A3 (en) * 1995-08-05 1998-08-05 British Biotech Pharm Imidazopyridine derivatives, method for producing thereof, pharmaceutical composition containing same and their use
SE9801526D0 (sv) * 1998-04-29 1998-04-29 Astra Ab New compounds
CA2774959C (en) 2000-08-04 2016-05-31 Dmi Biosciences, Inc. Method of using diketopiperazines and composition containing them
EP2517722B1 (en) 2003-05-15 2016-03-02 Ampio Pharmaceuticals, Inc. Synthesis of diketopiperazines
US7687515B2 (en) * 2006-01-17 2010-03-30 N.V. Organon 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
RU2475485C2 (ru) 2008-01-30 2013-02-20 Ниппон Дзоки Фармасьютикал Ко., Лтд. Производное пиперидина
JP5856843B2 (ja) 2008-05-27 2016-02-10 アンピオ ファーマシューティカルズ，インコーポレイテッド ジケトピペラジンを用いた医薬組成物
JP5978296B2 (ja) * 2011-06-28 2016-08-24 フジアン・ミンドン・レジュヴネイション・ファーマスーティカル・カンパニー・リミテッド 抗アレルギ性ベンゾシクロヘプタチオフェン誘導体
EA028343B1 (ru) 2011-10-10 2017-11-30 Ампио Фармасьютикалз, Инк. Лечение дегенеративного заболевания сустава
PH12014500686A1 (en) 2011-10-10 2020-12-18 Ampio Pharmaceuticals Inc Implantable medical devices with increased immune tolerance, and methods for making and implanting
MX355446B (es) * 2011-10-28 2018-04-18 Ampio Pharmaceuticals Inc Tratamiento de rinitis.
US9808454B2 (en) 2013-03-15 2017-11-07 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
EP3183240A4 (en) 2014-08-18 2018-06-27 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
EP3310375A4 (en) 2015-06-22 2019-02-20 Ampio Pharmaceuticals, Inc. USE OF LOW-MOLECULAR FRACTIONS OF HUMAN SERUMALBUMINE IN THE TREATMENT OF ILLNESSES
CN113880801A (zh) * 2020-07-03 2022-01-04 合肥医工医药股份有限公司 一类三环化合物、其制备方法及其医药用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL132137C (Sortimente) * 1963-04-24
EP0404797B1 (en) * 1988-03-15 1995-02-01 G.D. Searle & Co. 1H/3H-[4-(N,N-CYCLOALKYL AND/OR BRANCHED-ALKYLCARBOXAMIDO) -BENZYL]IMIDAZO[4,5-c]PYRIDINES AS PAF ANTAGONISTS
NZ228889A (en) * 1988-04-28 1991-09-25 Schering Corp Fused tri- or tetracyclic heterocyclic compounds and pharmaceutical compositions
US5250681A (en) * 1988-06-02 1993-10-05 Ajinomoto Co., Inc. Piperidine derivatives and hypotensives containing the same
US5114919A (en) * 1990-02-26 1992-05-19 Merck & Co., Inc. Adjuncts in cancer chemotherapy
ES2061247T3 (es) * 1990-05-09 1994-12-01 Pfizer Imidazo (4,5-c) piridinas con actividad antagonista del paf.

Also Published As

Publication number Publication date
IE920449A1 (en) 1992-08-12
MX9200589A (es) 1992-10-01
FI933531A7 (fi) 1993-08-10
MY108437A (en) 1996-09-30
HU211202A9 (en) 1995-11-28
DE69200304D1 (de) 1994-09-08
BR9205615A (pt) 1994-05-17
CN1064275A (zh) 1992-09-09
EG20085A (en) 1997-05-31
WO1992014734A1 (en) 1992-09-03
CZ280504B6 (cs) 1996-02-14
EP0572425A1 (en) 1993-12-08
YU14392A (sh) 1994-11-15
CN1040326C (zh) 1998-10-21
HU9302327D0 (en) 1993-10-28
EP0572425B1 (en) 1994-08-03
CA2099381A1 (en) 1992-08-14
DE69200304T2 (de) 1994-12-08
NO932889L (no) 1993-08-13
CS42592A3 (en) 1992-09-16
PL169304B1 (pl) 1996-06-28
JPH06504992A (ja) 1994-06-09
ZA921005B (en) 1993-08-12
FI933531A0 (fi) 1993-08-10
AU650322B2 (en) 1994-06-16
IL100887A (en) 1996-01-19
YU48238B (sh) 1997-08-22
HUT65947A (en) 1994-08-29
TW227000B (Sortimente) 1994-07-21
US5358953A (en) 1994-10-25
JP2506541B2 (ja) 1996-06-12
IL100887A0 (en) 1992-11-15
CA2099381C (en) 1996-07-09
KR970005302B1 (ko) 1997-04-15
IE65125B1 (en) 1995-10-04
ES2059212T3 (es) 1994-11-01
NZ241597A (en) 1993-04-28
DK0572425T3 (da) 1994-09-12
AU1168392A (en) 1992-09-15
RU2114845C1 (ru) 1998-07-10
NO932889D0 (no) 1993-08-13
GB9102997D0 (en) 1991-03-27
FI933531L (fi) 1993-08-10
ATE109482T1 (de) 1994-08-15

Similar Documents

Publication Publication Date Title
NO300592B1 (no) Imidazopyridin PAF/H1 antagonister
US4879293A (en) Pyrrols [3,4-8]pyrazine derivatives, their production and use as anti-anxiety agents
US5089496A (en) Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies
EP1343761B1 (en) Piperidine mch antagonists and their use in the treatment of obesity
JPH0678316B2 (ja) ベンゾ〔５，６〕シクロヘプタピリジン類、組成物および使用法
JPH0761998B2 (ja) ビス―ベンゾまたはベンゾピリドシクロヘプタピペリジン、ピペリジリデンおよびピペラジン化合物および組成物
MXPA04007743A (es) Nuevos derivados de piridina y quinolina.
JP2008525416A (ja) Ｇタンパク質共役受容体（ｇｐｒ１１６）作動薬および肥満および糖尿病治療のためのその使用
JPH0678315B2 (ja) 新規なベンゾピリド‐ピペリジン、ピペリジリデンおよびピペラジン化合物、組成物、製造法および利用法
SK70899A3 (en) 6-phenylpyridyl-2-amine derivatives useful as nos inhibitors
US5250531A (en) Dihydropyrimidine antiallergy agents
JP2003527426A (ja) トロンビン阻害薬
JPH07505394A (ja) 橋渡しビスアリールカルビノール誘導体，組成物および使用法
US6040309A (en) Benzothiophene derivatives useful in therapy
US4192944A (en) Optionally substituted 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-N-(1H-tetrazol-4-yl)carboxamides and their use as antiallergy agents
CZ111192A3 (en) Condensed diazepinones, process of their preparation and pharmaceutical compositions in which they are comprised
AU2006201994A1 (en) New phenylpyridinylpiperazine compounds, a process for their preparation and pharmaceutical compositions containing them
US5438062A (en) Benzo(5,6)cycloheptapyridines, compositions and methods of use
FI101225B (fi) Menetelmä terapeuttisesti käyttökelpoisten 2-metyyli-imidatso£4,5-c|py rid-1-yylijohdannaisten valmistamiseksi
US5665726A (en) Benzo[5,6]cycloheptapyridines, compositions and methods of use
JPH064637B2 (ja) 新規なインドール誘導体
KR20000069063A (ko) Ｎ-(이미다졸릴부틸)벤젠설폰아미드 유도체, 이들의 제법 및치료에의 응용
JPH05507932A (ja) イミダゾピリジンｐａｆ拮抗薬
JPH11503130A (ja) 新規方法
PT100223B (pt) Processo para a preparacao de imidazopiridinas antagonistas de paf/h1