NO300129B1 - Nye 9-amino-7-substituerte-6-demetyl-6-deoksytetracykliner, og fremgangsmåte til fremstilling derav - Google Patents
Nye 9-amino-7-substituerte-6-demetyl-6-deoksytetracykliner, og fremgangsmåte til fremstilling derav Download PDFInfo
- Publication number
- NO300129B1 NO300129B1 NO923856A NO923856A NO300129B1 NO 300129 B1 NO300129 B1 NO 300129B1 NO 923856 A NO923856 A NO 923856A NO 923856 A NO923856 A NO 923856A NO 300129 B1 NO300129 B1 NO 300129B1
- Authority
- NO
- Norway
- Prior art keywords
- methylpropyl
- ethyl
- dimethylamino
- amino
- octahydro
- Prior art date
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- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims description 44
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
- C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
- C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
- C07C2603/44—Naphthacenes; Hydrogenated naphthacenes
- C07C2603/46—1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/771,697 US5281628A (en) | 1991-10-04 | 1991-10-04 | 9-amino-7-(substituted)-6-demethyl-6-deoxytetracyclines |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO923856D0 NO923856D0 (no) | 1992-10-02 |
| NO923856L NO923856L (no) | 1993-04-05 |
| NO300129B1 true NO300129B1 (no) | 1997-04-14 |
Family
ID=25092681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO923856A NO300129B1 (no) | 1991-10-04 | 1992-10-02 | Nye 9-amino-7-substituerte-6-demetyl-6-deoksytetracykliner, og fremgangsmåte til fremstilling derav |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US5281628A (da) |
| EP (1) | EP0535346B1 (da) |
| JP (1) | JP3183729B2 (da) |
| KR (1) | KR100261528B1 (da) |
| CN (1) | CN1053182C (da) |
| AT (1) | ATE129697T1 (da) |
| AU (1) | AU651734B2 (da) |
| CA (1) | CA2079703C (da) |
| CZ (1) | CZ285015B6 (da) |
| DE (1) | DE69205792T2 (da) |
| DK (1) | DK0535346T3 (da) |
| ES (1) | ES2081005T3 (da) |
| FI (1) | FI111716B (da) |
| GR (1) | GR3017978T3 (da) |
| HK (1) | HK1000319A1 (da) |
| HU (2) | HU211214B (da) |
| IL (1) | IL103319A (da) |
| MX (1) | MX9205573A (da) |
| NO (1) | NO300129B1 (da) |
| NZ (1) | NZ244556A (da) |
| PH (1) | PH30343A (da) |
| PL (2) | PL170939B1 (da) |
| SK (1) | SK281113B6 (da) |
| TW (1) | TW222616B (da) |
| ZA (1) | ZA927608B (da) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE40183E1 (en) | 1991-10-04 | 2008-03-25 | Wyeth Holdings Corporation | 7-Substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines |
| US5494903A (en) | 1991-10-04 | 1996-02-27 | American Cyanamid Company | 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines |
| ATE271614T1 (de) * | 1992-05-28 | 2004-08-15 | Ct For Molecular Biology And M | Quinone-derivate zur verbesserung der zellulare bioenergie |
| US5328902A (en) * | 1992-08-13 | 1994-07-12 | American Cyanamid Co. | 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines |
| US5442059A (en) * | 1992-08-13 | 1995-08-15 | American Cyanamid Company | 9-[(substituted glycyl)amido)]-6-demethyl-6-deoxytetracyclines |
| US5420272A (en) * | 1992-08-13 | 1995-05-30 | American Cyanamid Company | 7-(substituted)-8-(substituted)-9-](substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines |
| US5371076A (en) * | 1993-04-02 | 1994-12-06 | American Cyanamid Company | 9-[(substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines |
| JP2784847B2 (ja) * | 1994-02-17 | 1998-08-06 | ファイザー インク． | ９−（置換アミノ）−アルファ−６−デオキシ−５−オキシテトラサイクリン誘導体、それらの製造及び、抗生物質としてのそれらの使用 |
| CA2318580A1 (en) * | 1998-01-23 | 1999-07-29 | Mark L. Nelson | Pharmaceutically active compounds and methods of use thereof |
| EP2327686A3 (en) * | 1999-09-14 | 2012-08-22 | Trustees Of Tufts College | Methods of preparing substituted tetracyclines with transition metal-based chemistries |
| US8106225B2 (en) * | 1999-09-14 | 2012-01-31 | Trustees Of Tufts College | Methods of preparing substituted tetracyclines with transition metal-based chemistries |
| US6686365B2 (en) * | 2000-02-04 | 2004-02-03 | Eli Lilly And Company | Pharmaceutical composition |
| WO2001098236A2 (en) * | 2000-06-16 | 2001-12-27 | Trustees Of Tufts College | 7-phenyl-substituted tetracycline compounds |
| US20020132798A1 (en) * | 2000-06-16 | 2002-09-19 | Nelson Mark L. | 7-phenyl-substituted tetracycline compounds |
| AU2001271642B2 (en) * | 2000-07-07 | 2006-01-05 | Paratek Pharmaceuticals, Inc. | 7-substituted tetracycline compounds |
| US7094806B2 (en) | 2000-07-07 | 2006-08-22 | Trustees Of Tufts College | 7, 8 and 9-substituted tetracycline compounds |
| MXPA03000055A (es) * | 2000-07-07 | 2003-07-14 | Tufts College | Compuestos de monociclina sustituidos en posicion 9.. |
| US7553828B2 (en) | 2001-03-13 | 2009-06-30 | Paratek Pharmaceuticals, Inc. | 9-aminomethyl substituted minocycline compounds |
| WO2002072506A2 (en) | 2001-03-13 | 2002-09-19 | Paratek Pharmaceuticals, Inc. | 7-pyrollyl tetracycline compounds and methods of use thereof |
| EP1241160A1 (en) * | 2001-03-13 | 2002-09-18 | Glaxo Group Limited | Tetracycline derivatives and their use as antibiotic agents |
| JP2005506291A (ja) * | 2001-03-13 | 2005-03-03 | パラテック ファーマシューティカルズ， インク． | ７，９−置換テトラサイクリン化合物 |
| EP2332550A1 (en) | 2001-07-13 | 2011-06-15 | Paratek Pharmaceuticals, Inc. | Tetracyclines for the treatment of neurodegenerative diseases |
| US20060194773A1 (en) * | 2001-07-13 | 2006-08-31 | Paratek Pharmaceuticals, Inc. | Tetracyline compounds having target therapeutic activities |
| WO2003055441A2 (en) * | 2001-08-02 | 2003-07-10 | Paratek Pharmaceuticals, Inc. | Medicaments |
| US20030181371A1 (en) * | 2001-12-28 | 2003-09-25 | Angiotech Pharmaceuticals, Inc. | Compositions and methods of using collajolie |
| EP2311799A1 (en) * | 2002-01-08 | 2011-04-20 | Paratek Pharmaceuticals, Inc. | 4-dedimethylamino tetracycline compounds |
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1991
- 1991-10-04 US US07/771,697 patent/US5281628A/en not_active Expired - Lifetime
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1992
- 1992-08-18 DK DK92114054.7T patent/DK0535346T3/da active
- 1992-08-18 AT AT92114054T patent/ATE129697T1/de not_active IP Right Cessation
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- 1992-08-19 TW TW081106574A patent/TW222616B/zh active
- 1992-09-28 JP JP28114692A patent/JP3183729B2/ja not_active Expired - Fee Related
- 1992-09-29 SK SK2972-92A patent/SK281113B6/sk unknown
- 1992-09-29 CZ CS922972A patent/CZ285015B6/cs not_active IP Right Cessation
- 1992-09-30 NZ NZ244556A patent/NZ244556A/xx unknown
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- 1992-10-02 NO NO923856A patent/NO300129B1/no not_active IP Right Cessation
- 1992-10-02 PH PH45040A patent/PH30343A/en unknown
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- 1992-10-02 KR KR1019920018123A patent/KR100261528B1/ko not_active IP Right Cessation
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