NO2776305T3 - - Google Patents

Info

Publication number
NO2776305T3
NO2776305T3 NO12790406A NO12790406A NO2776305T3 NO 2776305 T3 NO2776305 T3 NO 2776305T3 NO 12790406 A NO12790406 A NO 12790406A NO 12790406 A NO12790406 A NO 12790406A NO 2776305 T3 NO2776305 T3 NO 2776305T3
Authority
NO
Norway
Application number
NO12790406A
Other languages
Norwegian (no)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NO2776305T3 publication Critical patent/NO2776305T3/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
NO12790406A 2014-04-23 2012-11-06 NO2776305T3 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461983152P 2014-04-23 2014-04-23

Publications (1)

Publication Number Publication Date
NO2776305T3 true NO2776305T3 (tr) 2018-01-27

Family

ID=53055121

Family Applications (1)

Application Number Title Priority Date Filing Date
NO12790406A NO2776305T3 (tr) 2014-04-23 2012-11-06

Country Status (37)

Country Link
US (3) US9908927B2 (tr)
EP (2) EP3366699A1 (tr)
JP (2) JP6523331B2 (tr)
KR (2) KR102079919B1 (tr)
CN (2) CN106459221B (tr)
AR (1) AR100168A1 (tr)
AU (3) AU2015249649B2 (tr)
BR (1) BR112016024515B1 (tr)
CA (2) CA3184067A1 (tr)
CL (1) CL2016002683A1 (tr)
CR (1) CR20160516A (tr)
CY (1) CY1120281T1 (tr)
DK (1) DK3134430T3 (tr)
DO (1) DOP2016000284A (tr)
EC (1) ECSP16089579A (tr)
ES (1) ES2672368T3 (tr)
HR (1) HRP20180950T1 (tr)
HU (1) HUE038914T2 (tr)
IL (2) IL248244B (tr)
LT (1) LT3134430T (tr)
MA (2) MA39770A (tr)
MX (2) MX2016013858A (tr)
MY (1) MY181986A (tr)
NO (1) NO2776305T3 (tr)
PE (1) PE20170299A1 (tr)
PH (1) PH12016502079B1 (tr)
PL (1) PL3134430T3 (tr)
PT (1) PT3134430T (tr)
RS (1) RS57153B1 (tr)
RU (1) RU2699285C2 (tr)
SG (3) SG11201608767XA (tr)
SI (1) SI3134430T1 (tr)
TR (1) TR201806912T4 (tr)
TW (2) TWI683825B (tr)
UA (1) UA118286C2 (tr)
UY (1) UY36095A (tr)
WO (1) WO2015164588A1 (tr)

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CA2984350A1 (en) * 2015-05-04 2016-11-10 Apogenix Ag Single-chain cd40-receptor agonist proteins
EP3365363A1 (en) * 2015-10-23 2018-08-29 Apogenix AG Single-chain gitr-receptor agonist proteins
AU2016342420B2 (en) * 2015-10-23 2020-10-01 Apogenix Ag Single-chain LIGHT receptor agonist proteins
JP6917368B2 (ja) 2015-10-23 2021-08-11 アポジェニックス アーゲー 一本鎖cd27受容体アゴニストタンパク質
WO2017102010A1 (en) * 2015-12-17 2017-06-22 Biontech Rna Pharmaceuticals Gmbh Novel cytokine fusion proteins
WO2017151707A1 (en) 2016-03-01 2017-09-08 The Board Of Trustees Of The University Of Illinois L-asparaginase variants and fusion proteins with reduced l-glutaminase activity and enhanced stability
AU2017234679A1 (en) * 2016-03-16 2018-08-30 Merrimack Pharmaceuticals, Inc. Engineered trail for cancer therapy
US10501744B2 (en) 2016-05-04 2019-12-10 Indiana University Research And Technology Corporation Presentation of bioactive proteins
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Hdac抑制劑與pd-l1抑制劑之組合治療
CA3027380A1 (en) * 2016-06-13 2017-12-21 Merrimack Pharmaceuticals, Inc. Methods for selecting and treating patients with a trail-based therapeutic or death receptor agonist
EP3360898A1 (en) 2017-02-14 2018-08-15 Boehringer Ingelheim International GmbH Bispecific anti-tnf-related apoptosis-inducing ligand receptor 2 and anti-cadherin 17 binding molecules for the treatment of cancer
US11578315B2 (en) 2017-08-11 2023-02-14 The Board Of Trustees Of The University Of Illinois Truncated guinea pig L-asparaginase variants and methods of use
TW202003553A (zh) * 2018-03-15 2020-01-16 美商艾伯維有限公司 用於治療癌症之abbv-621與抗癌劑之組合
TW202002952A (zh) * 2018-03-15 2020-01-16 美商艾伯維有限公司 用於治療胰臟癌之abbv-621與抗癌劑之組合
US20230212260A1 (en) 2020-05-15 2023-07-06 Apogenix Ag Multi-specific immune modulators
WO2022248662A1 (en) 2021-05-28 2022-12-01 Julius-Maximilians-Universität Würzburg Recombinant proteinaceous binding molecules
WO2023088876A1 (en) 2021-11-16 2023-05-25 Apogenix Ag Multi-specific immune modulators

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR025984A1 (es) 1999-10-07 2002-12-26 Maxygen Aps Polipeptidos oligomericos de cadena simple
DE19963859A1 (de) 1999-12-30 2001-07-12 Apotech Res & Dev Ltd Bi- oder Oligomer eines Di-, Tri-, Quattro- oder Pentamers von rekombinanten Fusionsproteinen
CA2314199A1 (en) 2000-07-21 2002-01-21 Robert Simoneau C-chip
KR100942864B1 (ko) * 2000-12-07 2010-02-17 일라이 릴리 앤드 캄파니 Glp-1 융합 단백질
US7317091B2 (en) 2002-03-01 2008-01-08 Xencor, Inc. Optimized Fc variants
AU2003234274A1 (en) 2002-04-26 2003-11-10 California Institute Of Technology D1-1 nucleic acids, polypeptides and related methods
DE102004014983A1 (de) 2004-03-26 2005-10-20 Univ Stuttgart Rekombinante Polypeptide der Mitglieder der TNF Ligandenfamilie und deren Verwendung
US20060188498A1 (en) * 2005-02-18 2006-08-24 Genentech, Inc. Methods of using death receptor agonists and EGFR inhibitors
CN101160323A (zh) * 2005-04-15 2008-04-09 拉帕波特家族医学科学研究所 用于治疗mcp-1/ccr2相关疾病的分子及其使用方法
EP1874816A4 (en) 2005-04-26 2010-08-25 Medimmune Inc MODULATION OF THE ANTIBODY EFFECTOR FUNCTION BY "HINGE" DOMENGINE ENGINEERING
EP1894940A1 (en) 2006-08-28 2008-03-05 Apogenix GmbH TNF superfamily fusion proteins
EP3321277B1 (en) 2007-07-10 2019-09-18 Apogenix AG Tnf superfamily collectin fusion proteins
CA2726087A1 (en) 2008-06-03 2009-12-10 Tariq Ghayur Dual variable domain immunoglobulins and uses thereof
PL2310509T3 (pl) 2008-07-21 2015-08-31 Apogenix Ag Jednołańcuchowe cząsteczki TNFSF
CA2737280A1 (en) * 2008-09-22 2010-03-25 Amgen Inc. Method of treatment
AU2009303304A1 (en) * 2008-10-10 2010-04-15 Anaphore, Inc. Polypeptides that bind TRAIL-RI and TRAIL-R2
WO2010078966A1 (en) 2009-01-09 2010-07-15 Apogenix Gmbh Fusion proteins forming trimers
JP2012515556A (ja) * 2009-01-23 2012-07-12 バイオジェン・アイデック・エムエイ・インコーポレイテッド 低下したエフェクタ機能を有する安定化Fcポリペプチドおよび使用方法
EP2516458A1 (en) 2009-12-22 2012-10-31 Novartis AG Tetravalent cd47-antibody constant region fusion protein for use in therapy
KR101747991B1 (ko) 2010-04-13 2017-06-19 메디뮨 엘엘씨 Trail r2 특이적 다량체 스캐폴드
CA2858806A1 (en) * 2011-12-23 2013-06-27 Innate Pharma Enzymatic conjugation of polypeptides
CA2877989C (en) * 2012-07-18 2021-05-25 Apogenix Gmbh Shortened cd95-fc variants

Also Published As

Publication number Publication date
MA45069A (fr) 2019-04-03
MX2016013858A (es) 2017-08-02
AR100168A1 (es) 2016-09-14
ES2672368T3 (es) 2018-06-14
CR20160516A (es) 2017-05-10
US20180222962A1 (en) 2018-08-09
ECSP16089579A (es) 2018-05-31
HRP20180950T1 (hr) 2018-08-10
PL3134430T3 (pl) 2018-08-31
DK3134430T3 (en) 2018-05-22
TW202024123A (zh) 2020-07-01
CY1120281T1 (el) 2019-07-10
IL248244B (en) 2020-03-31
CN111718424A (zh) 2020-09-29
IL272612A (en) 2020-03-31
TW201620928A (zh) 2016-06-16
WO2015164588A1 (en) 2015-10-29
JP6523331B2 (ja) 2019-05-29
RU2016145608A (ru) 2018-05-28
RU2016145608A3 (tr) 2018-12-26
JP2019162114A (ja) 2019-09-26
US20150337027A1 (en) 2015-11-26
AU2018271369B2 (en) 2020-01-02
RS57153B1 (sr) 2018-07-31
US20210040178A1 (en) 2021-02-11
DOP2016000284A (es) 2017-02-15
NZ725476A (en) 2023-09-29
BR112016024515A2 (pt) 2017-10-10
RU2699285C2 (ru) 2019-09-04
AU2015249649B2 (en) 2018-10-04
KR20170012257A (ko) 2017-02-02
PH12016502079A1 (en) 2016-12-19
TWI747178B (zh) 2021-11-21
PT3134430T (pt) 2018-04-20
SI3134430T1 (en) 2018-05-31
KR102079919B1 (ko) 2020-02-24
EP3134430B1 (en) 2018-03-21
CA2946402C (en) 2023-02-28
US9908927B2 (en) 2018-03-06
CL2016002683A1 (es) 2017-07-07
UY36095A (es) 2015-10-30
MY181986A (en) 2021-01-18
TR201806912T4 (tr) 2018-06-21
PH12016502079B1 (en) 2016-12-19
CA2946402A1 (en) 2015-10-29
SG10202111785VA (en) 2021-12-30
SG10201806465TA (en) 2018-08-30
JP2017513503A (ja) 2017-06-01
UA118286C2 (uk) 2018-12-26
CA3184067A1 (en) 2015-10-29
CN106459221A (zh) 2017-02-22
AU2018271369A1 (en) 2018-12-20
LT3134430T (lt) 2018-05-10
IL248244A0 (en) 2016-11-30
MX2019013587A (es) 2020-01-13
AU2015249649A1 (en) 2016-11-10
CN106459221B (zh) 2020-09-01
EP3366699A1 (en) 2018-08-29
KR20190135546A (ko) 2019-12-06
EP3134430A1 (en) 2017-03-01
TWI683825B (zh) 2020-02-01
AU2020202247A1 (en) 2020-04-23
HUE038914T2 (hu) 2018-12-28
JP6714751B2 (ja) 2020-06-24
PE20170299A1 (es) 2017-05-06
BR112016024515B1 (pt) 2020-03-31
SG11201608767XA (en) 2016-11-29
MA39770A (fr) 2015-10-29

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