NO2776305T3 - - Google Patents

Info

Publication number
NO2776305T3
NO2776305T3 NO12790406A NO12790406A NO2776305T3 NO 2776305 T3 NO2776305 T3 NO 2776305T3 NO 12790406 A NO12790406 A NO 12790406A NO 12790406 A NO12790406 A NO 12790406A NO 2776305 T3 NO2776305 T3 NO 2776305T3
Authority
NO
Norway
Application number
NO12790406A
Other languages
Norwegian (no)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NO2776305T3 publication Critical patent/NO2776305T3/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
NO12790406A 2014-04-23 2012-11-06 NO2776305T3 (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461983152P 2014-04-23 2014-04-23

Publications (1)

Publication Number Publication Date
NO2776305T3 true NO2776305T3 (ko) 2018-01-27

Family

ID=53055121

Family Applications (1)

Application Number Title Priority Date Filing Date
NO12790406A NO2776305T3 (ko) 2014-04-23 2012-11-06

Country Status (37)

Country Link
US (4) US9908927B2 (ko)
EP (2) EP3366699A1 (ko)
JP (2) JP6523331B2 (ko)
KR (2) KR102079919B1 (ko)
CN (2) CN111718424A (ko)
AR (1) AR100168A1 (ko)
AU (3) AU2015249649B2 (ko)
BR (1) BR112016024515B1 (ko)
CA (2) CA3184067A1 (ko)
CL (1) CL2016002683A1 (ko)
CR (1) CR20160516A (ko)
CY (1) CY1120281T1 (ko)
DK (1) DK3134430T3 (ko)
DO (1) DOP2016000284A (ko)
EC (1) ECSP16089579A (ko)
ES (1) ES2672368T3 (ko)
HR (1) HRP20180950T1 (ko)
HU (1) HUE038914T2 (ko)
IL (2) IL248244B (ko)
LT (1) LT3134430T (ko)
MA (2) MA39770A (ko)
MX (2) MX2016013858A (ko)
MY (1) MY181986A (ko)
NO (1) NO2776305T3 (ko)
PE (1) PE20170299A1 (ko)
PH (1) PH12016502079B1 (ko)
PL (1) PL3134430T3 (ko)
PT (1) PT3134430T (ko)
RS (1) RS57153B1 (ko)
RU (1) RU2699285C2 (ko)
SG (3) SG10201806465TA (ko)
SI (1) SI3134430T1 (ko)
TR (1) TR201806912T4 (ko)
TW (2) TWI747178B (ko)
UA (1) UA118286C2 (ko)
UY (1) UY36095A (ko)
WO (1) WO2015164588A1 (ko)

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EP3292143B1 (en) * 2015-05-04 2019-08-21 Apogenix AG Single-chain cd40-receptor agonist proteins
CN108430492B (zh) 2015-10-23 2022-05-03 阿珀吉科吉尼科斯股份公司 单链cd27受体激动剂蛋白
WO2017068180A1 (en) * 2015-10-23 2017-04-27 Apogenix Ag Single-chain light receptor agonist proteins
WO2017068185A1 (en) * 2015-10-23 2017-04-27 Apogenix Ag Single-chain gitr-receptor agonist proteins
WO2017102010A1 (en) * 2015-12-17 2017-06-22 Biontech Rna Pharmaceuticals Gmbh Novel cytokine fusion proteins
EP3423480A1 (en) 2016-03-01 2019-01-09 The Board of Trustees of the University of Illinois L-asparaginase variants and fusion proteins with reduced l-glutaminase activity and enhanced stability
WO2017161173A1 (en) * 2016-03-16 2017-09-21 Merrimack Pharmaceuticals, Inc. Engineered trail for cancer therapy
US10501744B2 (en) 2016-05-04 2019-12-10 Indiana University Research And Technology Corporation Presentation of bioactive proteins
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Hdac抑制劑與pd-l1抑制劑之組合治療
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
WO2017218540A1 (en) * 2016-06-13 2017-12-21 Merrimack Pharmaceuticals, Inc. Methods for selecting and treating patients with a trail-based therapeutic or death receptor agonist
EP3360898A1 (en) 2017-02-14 2018-08-15 Boehringer Ingelheim International GmbH Bispecific anti-tnf-related apoptosis-inducing ligand receptor 2 and anti-cadherin 17 binding molecules for the treatment of cancer
US11578315B2 (en) 2017-08-11 2023-02-14 The Board Of Trustees Of The University Of Illinois Truncated guinea pig L-asparaginase variants and methods of use
WO2019178433A1 (en) 2018-03-15 2019-09-19 Abbvie Inc. Abbv-621 in combination with anti-cancer agents for the treatment of pancreatic cancer
WO2019178438A1 (en) 2018-03-15 2019-09-19 Abbvie Inc. Abbv-621 in combination with anti-cancer agents for the treatment of cancer
CN115836084A (zh) 2020-05-15 2023-03-21 阿珀吉尼科斯股份公司 多特异性免疫调节剂
US20240294673A1 (en) 2021-05-28 2024-09-05 Julius-Maximilians-Universitaet Wuerzburg Recombinant proteinaceous binding molecules
WO2023088876A1 (en) 2021-11-16 2023-05-25 Apogenix Ag Multi-specific immune modulators

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001025277A1 (en) 1999-10-07 2001-04-12 Maxygen Aps Single-chain antagonist polypeptides
DE19963859A1 (de) 1999-12-30 2001-07-12 Apotech Res & Dev Ltd Bi- oder Oligomer eines Di-, Tri-, Quattro- oder Pentamers von rekombinanten Fusionsproteinen
CA2314199A1 (en) 2000-07-21 2002-01-21 Robert Simoneau C-chip
CZ306180B6 (cs) 2000-12-07 2016-09-14 Eli Lilly And Company GLP-1 fúzní proteiny
US7317091B2 (en) 2002-03-01 2008-01-08 Xencor, Inc. Optimized Fc variants
WO2003091447A2 (en) 2002-04-26 2003-11-06 California Institute Of Technology D1-1 nucleic acids, polypeptides and related methods
DE102004014983A1 (de) 2004-03-26 2005-10-20 Univ Stuttgart Rekombinante Polypeptide der Mitglieder der TNF Ligandenfamilie und deren Verwendung
US20060188498A1 (en) * 2005-02-18 2006-08-24 Genentech, Inc. Methods of using death receptor agonists and EGFR inhibitors
MX2007010484A (es) 2005-04-15 2007-10-15 Rappaport Family Inst For Res Moleculas y metodos para usarlas para tratar enfermedades asociadas con mcp-1/ccr2.
US8008443B2 (en) 2005-04-26 2011-08-30 Medimmune, Llc Modulation of antibody effector function by hinge domain engineering
EP1894940A1 (en) 2006-08-28 2008-03-05 Apogenix GmbH TNF superfamily fusion proteins
EP2176288B1 (en) 2007-07-10 2015-11-04 Apogenix GmbH Tnf superfamily collectin fusion proteins
EP2297209A4 (en) 2008-06-03 2012-08-01 Abbott Lab IMMUNOGLOBULINS WITH TWO VARIABLE DOMAINS AND USES THEREOF
CA3092223C (en) 2008-07-21 2023-01-03 Apogenix Ag Tnfsf single chain molecules
AU2009293545A1 (en) 2008-09-22 2010-03-25 Amgen Inc. Method of treatment
US20100105620A1 (en) * 2008-10-10 2010-04-29 Anaphore, Inc. Polypeptides that bind Trail-R1 and Trail-R2
US8664366B2 (en) 2009-01-09 2014-03-04 Apogenix Gmbh Fusion proteins forming trimers
JP2012515556A (ja) * 2009-01-23 2012-07-12 バイオジェン・アイデック・エムエイ・インコーポレイテッド 低下したエフェクタ機能を有する安定化Fcポリペプチドおよび使用方法
JP2013514795A (ja) * 2009-12-22 2013-05-02 ノバルティス アーゲー 治療における使用のための四価cd47抗体定常領域融合タンパク質
US20130079280A1 (en) * 2010-04-13 2013-03-28 Medlmmune, Llc Fibronectin type iii domain-based multimeric scaffolds
EP2793949B1 (en) * 2011-12-23 2018-08-22 Innate Pharma Enzymatic conjugation of antibodies
CN104640876A (zh) 2012-07-18 2015-05-20 阿珀吉尼科斯有限公司 包含CD95-Fc同种型的混合物的组合物

Also Published As

Publication number Publication date
MX2016013858A (es) 2017-08-02
IL248244A0 (en) 2016-11-30
UY36095A (es) 2015-10-30
PL3134430T3 (pl) 2018-08-31
AU2015249649B2 (en) 2018-10-04
UA118286C2 (uk) 2018-12-26
PH12016502079A1 (en) 2016-12-19
CN111718424A (zh) 2020-09-29
US20180222962A1 (en) 2018-08-09
DK3134430T3 (en) 2018-05-22
RU2016145608A3 (ko) 2018-12-26
SG10201806465TA (en) 2018-08-30
SI3134430T1 (en) 2018-05-31
TW201620928A (zh) 2016-06-16
US20150337027A1 (en) 2015-11-26
RU2699285C2 (ru) 2019-09-04
PE20170299A1 (es) 2017-05-06
MX2019013587A (es) 2020-01-13
IL272612A (en) 2020-03-31
TWI683825B (zh) 2020-02-01
TW202024123A (zh) 2020-07-01
JP6714751B2 (ja) 2020-06-24
US20210040178A1 (en) 2021-02-11
LT3134430T (lt) 2018-05-10
CA2946402A1 (en) 2015-10-29
AU2015249649A1 (en) 2016-11-10
JP6523331B2 (ja) 2019-05-29
HRP20180950T1 (hr) 2018-08-10
JP2019162114A (ja) 2019-09-26
AU2018271369B2 (en) 2020-01-02
DOP2016000284A (es) 2017-02-15
RS57153B1 (sr) 2018-07-31
KR20190135546A (ko) 2019-12-06
NZ725476A (en) 2023-09-29
EP3134430A1 (en) 2017-03-01
EP3134430B1 (en) 2018-03-21
ES2672368T3 (es) 2018-06-14
ECSP16089579A (es) 2018-05-31
AU2018271369A1 (en) 2018-12-20
CY1120281T1 (el) 2019-07-10
CN106459221A (zh) 2017-02-22
BR112016024515B1 (pt) 2020-03-31
US9908927B2 (en) 2018-03-06
MA45069A (fr) 2019-04-03
EP3366699A1 (en) 2018-08-29
HUE038914T2 (hu) 2018-12-28
AR100168A1 (es) 2016-09-14
MY181986A (en) 2021-01-18
SG10202111785VA (en) 2021-12-30
JP2017513503A (ja) 2017-06-01
CA2946402C (en) 2023-02-28
KR20170012257A (ko) 2017-02-02
RU2016145608A (ru) 2018-05-28
TWI747178B (zh) 2021-11-21
SG11201608767XA (en) 2016-11-29
CR20160516A (es) 2017-05-10
AU2020202247A1 (en) 2020-04-23
PH12016502079B1 (en) 2016-12-19
CL2016002683A1 (es) 2017-07-07
PT3134430T (pt) 2018-04-20
IL248244B (en) 2020-03-31
TR201806912T4 (tr) 2018-06-21
US20240174731A1 (en) 2024-05-30
CA3184067A1 (en) 2015-10-29
BR112016024515A2 (pt) 2017-10-10
KR102079919B1 (ko) 2020-02-24
CN106459221B (zh) 2020-09-01
MA39770A (fr) 2015-10-29
WO2015164588A1 (en) 2015-10-29

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